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Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 2010, Volume 118, Issue 3, pp. 177 - 187
Aldo-keto reductase (AKR) 1C3 (type 5 17β-hydroxysteroid dehydrogenase and prostaglandin F synthase), may stimulate proliferation via steroid hormone and... 
Estrogen receptor | Peroxisome proliferator activated receptor γ | Prostaglandin F synthase | Prostaglandin D 2 | 17β-Hydroxysteroid dehydrogenase | Prostaglandin D | SIGNALING PATHWAYS | 17-BETA-HYDROXYSTEROID DEHYDROGENASES | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKR1C3 | PROLIFERATOR-ACTIVATED RECEPTOR | RISK | Prostaglandin D-2 | CELECOXIB | ENDOCRINOLOGY & METABOLISM | PROGNOSTIC MARKER | F SYNTHASE | INHIBITORS | 17 beta-Hydroxysteroid dehydrogenase | AROMATASE | Peroxisome proliferator activated receptor | gamma | Up-Regulation | Prostaglandins - pharmacology | Humans | Gene Expression Regulation, Neoplastic | Dinoprost - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Androstenedione - metabolism | Breast Neoplasms - metabolism | Testosterone - metabolism | Breast Neoplasms - enzymology | Transfection | Prostaglandin D2 - metabolism | Prostaglandin D2 - analogs & derivatives | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | 5-alpha-Dihydroprogesterone - metabolism | Dinoprost - pharmacology | Etiocholanolone - metabolism | Estradiol - pharmacology | Dihydrotestosterone - metabolism | Recombinant Proteins - metabolism | Estradiol - metabolism | Estrone - pharmacology | Gonadal Steroid Hormones - metabolism | Biocatalysis | Etiocholanolone - analogs & derivatives | Gonadal Steroid Hormones - pharmacology | Progesterone - analogs & derivatives | Recombinant Proteins - genetics | 20-alpha-Dihydroprogesterone - metabolism | Androsterone - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Breast Neoplasms - genetics | Aldo-Keto Reductase Family 1 Member C3 | Estrone - metabolism | Progesterone - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Prostaglandin D2 - pharmacology | Ketosteroids - metabolism | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Prostaglandins - metabolism | Physiological aspects | Testosterone | Breast cancer | Progesterone | Estradiol | Synthetic prostaglandins F | Index Medicus
Journal Article
Steroids, ISSN 0039-128X, 2012, Volume 77, Issue 1, pp. 10 - 26
Dehydroepiandrosterone (DHEA) is a multifunctional steroid with a broad range of biological effects in humans and animals. DHEA can be converted to multiple... 
DHEA metabolites activities | Oxidative DHEA metabolism | Hydroxy-EpiA | Hydroxy-DHEA | Oxygenated DHEA metabolites | Epiandrosterone | SYSTEMIC-LUPUS-ERYTHEMATOSUS | MALIGNANT GLIOMA-CELLS | ANDROGEN RECEPTOR MODULATORS | BONE-MINERAL DENSITY | 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1 | HUMAN CYTOCHROME P4507B1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEX-STEROID-RECEPTORS | LIVER MICROSOMAL FRACTIONS | PROSTATE-CANCER CELLS | ENDOCRINOLOGY & METABOLISM | CHROMATOGRAPHY-MASS SPECTROMETRY | Neoplasms - metabolism | Receptors, Estrogen - metabolism | Reactive Oxygen Species - metabolism | Humans | Receptors, Androgen - metabolism | Male | Intestines - metabolism | Dehydroepiandrosterone - analogs & derivatives | Brain - metabolism | Inflammation - metabolism | Osteoporosis - metabolism | Female | Neoplasms - physiopathology | Dehydroepiandrosterone - metabolism | Osteoporosis - physiopathology | Rabbits | Cardiovascular Diseases - physiopathology | Cardiovascular Diseases - metabolism | Hydroxylation | Oxidation-Reduction | Liver - metabolism | Rats | Neurodegenerative Diseases - metabolism | Androsterone - metabolism | Androsterone - analogs & derivatives | Animals | Neurodegenerative Diseases - physiopathology | Mice | Inflammation - physiopathology | Physiological aspects | Osteoporosis | Androgens | Dehydroepiandrosterone | Metabolites | Alzheimer's disease
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2013, Volume 9, Issue 1, pp. 649 - n/a
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 04/2018, Volume 465, pp. 4 - 26
Androgens play an important role in metabolic homeostasis and reproductive health in both men and women. Androgen signalling is dependent on androgen receptor... 
Testosterone | Androgens | Steroid biosynthesis | Hormone-dependent cancer | 11-oxygenated androgens | Intracrinology | Dehydroepiandrosterone | Corticosteroids | Metabolites | Stein-Leventhal syndrome | Cytochrome P-450 | Physiological aspects | Progesterone | Hormones | Sulfates | Estradiol | Blood proteins | 11OHT, 11β-hydroxy-testosterone | E1S, estrone sulfate | STS, steroid sulfatase | CRPC, castration resistant prostate cancer | 17αHP, 5α-pregnane-17α-ol-3,20-one | CHOL, cholesterol | 11KA4, 11-keto-androstenedione | DHEA, dehydroepiandrosterone (androst-5-ene-3β-ol-17-one) | EpiAST, 5α-androstan-3β-ol-17-one | 5-diol, androst-5-ene-3β,17β-diol | Pdiol, 5α-pregnane-3α,17α-diol-20-one | PORD, cytochrome P450 oxidoreductase deficiency | 5α-dione, 5α-androstane-3,17-dione | EpiT, epitestosterone (17α-hydroxy-testosterone, androst-4-ene-17α-ol-3-one) | OATP, organic anion-transporting polypeptide | A4, androstenedione (androst-4-ene-3,17-dione) | SULT, sulfotransferase | ETIO, etiochonanolone (5β-androstan-3α-ol-17-one) | SHBG, sex hormone-binding globulin | T, testosterone (androst-4-ene-17β-ol-3-one) | CYP, cytochrome P450 | 3α-adiol, 5α-androstan-3α,17β-diol | 17OHPROG, 17α-hydroxy-progesterone | StAR, steroidogenic acute regulatory protein | UGT, uridine diphosphate-glucuronosyl transferase | PAPS, 3′-phospho-adenosine-5′-phosphosulfate | 11OHDHT, 11β-hydroxy-5α-dihydrotestosterone | DHEAS, dehydroepiandrosterone sulfate | 11KT, 11-keto-testosterone | HSD, hydroxysteroid dehydrogenase | 11OHA4, 11β-hydroxy-androstenedione | PROG, progesterone | AST, androsterone (5α-androstan-3α-ol-17-one) | AKR, aldo-keto reductase | PCOS, polycystic ovary syndrome | PREG, pregnenolone | E1, estrone | 11KDHT, 11-keto-5α-dihydrotestosterone | AR, androgen receptor | E2, estradiol | DHT, 5α-dihydrotestosterone (5α-androstan-17β-ol-3-one)
Journal Article
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 04/2013, Volume 65, Issue 4, pp. 521 - 527
Journal Article