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Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 16, pp. 12705 - 12717
Lung cancer is the most common malignant tumor with increasing angiopoietin-2 (Ang-2) and a high rate of metastasis. However, the mechanism of Ang-2 enhancing... 
Ang-2 | Prognosis | RNA interference | EMT | Lung cancer
Journal Article
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 11/2017, Volume 18, Issue 11, pp. 2937 - 2944
Objective: Carcinoma of the uterine cervix is either the first or second most common malignancy in Indian women, depending on the registry. Tumor growth and... 
Ang-2 | laminin | chemotherapy | VEGF | Cervical cancer
Journal Article
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, ISSN 2210-7789, 04/2019, Volume 16, pp. 105 - 111
Preeclampsia affects 3–5% of pregnancies worldwide and is the primary cause of maternal-fetal and neonatal mortality. Previous studies show that alterations in... 
ANG-1/ANG-2 | Cohort | Preeclampsia | ANG-1 | ANG-2 | PDGF AA | PlGF | Predictors | DIAGNOSIS | CAROLINA | ANGIOGENIC FACTORS | OBSTETRICS & GYNECOLOGY | UTERINE ARTERY DOPPLER | PERIPHERAL VASCULAR DISEASE
Journal Article
BMB Reports, ISSN 1976-6696, 2015, Volume 48, Issue 8, p. 429
Angiogenesis is a complex process involving dynamic interaction of various cell to cell interactions. Endothelial cell interactions regulated by growth... 
Angiogenesis | Endothelial junction | ANG-2 | VE-cadherin | YAP | Akt
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 03/2018, Volume 478, pp. 18 - 27
We estimated the diagnostic and prognostic value of serum angiopoietin-2 (Ang-2) in liver cancer patients. Tissue Ang-2 was measured using immunohistochemistry... 
Tumor marker | Ang-2 | Liver cancer | Liver function | Overall survival | PROTEIN | ANGIOGENESIS | PROGNOSIS | RECURRENCE | MEDICAL LABORATORY TECHNOLOGY | HUMAN HEPATOCELLULAR-CARCINOMA | EXPRESSION | Immunohistochemistry | Enzymes | Glycoproteins | Analysis
Journal Article
Life Sciences, ISSN 0024-3205, 10/2018, Volume 210, pp. 86 - 95
Acute respiratory distress syndrome (ARDS) is characterized by acute hypoxemia with diffuse alveolar damage and increased pulmonary microvascular permeability.... 
Honokiol | Sirt3 | Ang-2 | Pulmonary microvascular endothelial barrier | ARDS | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | OXIDATIVE STRESS | ACTIVATION | PERMEABILITY | KINASE | MUSCLE | ACUTE LUNG INJURY | RESPIRATORY-DISTRESS-SYNDROME | SHOCK | PHARMACOLOGY & PHARMACY | MICE | Acute respiratory distress syndrome | Permeability | Mitogens | Analysis | Endothelium
Journal Article
MOLECULES, ISSN 1420-3049, 08/2019, Volume 24, Issue 16, p. 2865
Vascular endothelial growth factor (VEGF) inhibition by the addition of bevacizumab to the chemotherapy regimen of metastatic colorectal cancer leads to an... 
anti-angiogenic therapy | ANGPT2 | colorectal cancer | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | CrossMab | vanucizumab | ANTITUMOR | CANCER | CHEMISTRY, MULTIDISCIPLINARY | SERUM ANGIOPOIETIN-2 | PATHWAY | ANGIOGENIC THERAPY | Ang-2 | bispecific antibody | bevacizumab | NORMALIZATION | EXPRESSION | MEDIATES RESISTANCE | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Medical Journal of Wuhan University, ISSN 1671-8852, 07/2017, Volume 38, Issue 4, pp. 552 - 555
Journal Article
by Xu, XF and Yan, YH and Xun, QY and Shi, JY and Kong, XY and Wu, J and Zhou, HJ
ONCOTARGETS AND THERAPY, ISSN 1178-6930, 2019, Volume 12, pp. 1215 - 1223
Background: Angiogenesis is critical for the growth and metastasis of solid tumors and is, therefore, an important therapeutic target. Despite the great... 
PATHWAYS | METASTASIS | angiogenesis | siRNA | TUMOR ANGIOGENESIS | COMBINATION | DELIVERY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LYMPH-NODE | MOUSE MODEL | Ang-2 | RESISTANCE | drug resistance | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Cancer Cell International, ISSN 1475-2867, 08/2016, Volume 16, Issue 1, p. 65
Background: Pancreatic cancer is currently one of the leading causes of cancer deaths without any effective therapies. Mir-145 has been found to be... 
Ang-2 | Angiogenesis | Pancreatic cancer | MiR-145 | METASTASIS | ANTIBODY | VEGF-A | HEPATOCELLULAR-CARCINOMA | INVASION | ONCOLOGY | DIRECTLY TARGETS | miR-145 | GROWTH-FACTOR | INHIBITORS | MICRORNA
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 380, Issue 2, pp. 525 - 533
Highlights • Anti-angiogenic therapies such as Ang-2 and VEGF targeted agents have been heavily pursued in oncologic settings. • Angiopoietin/Tie2 system plays... 
Hematology, Oncology and Palliative Medicine | Ang-2 targeting | Angiogenesis | Anti-angiogenic therapy | Combination therapy | VEGF targeting | VASCULAR DISRUPTING AGENTS | INHIBITS TUMOR-GROWTH | COMBRETASTATIN A4 PHOSPHATE | BREAST-CANCER | ANTIANGIOGENIC THERAPY | RECEPTOR TYROSINE KINASES | ONCOLOGY | TIE-2 LIGAND ANGIOPOIETIN-2 | ENDOTHELIAL GROWTH-FACTOR | DISEASE PROGRESSION | Neoplasms - metabolism | Receptor, TIE-2 - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Tumor Microenvironment | Drug Resistance, Neoplasm | Neoplasms - blood supply | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Molecular Targeted Therapy | Angiopoietin-2 - metabolism | Drug Discovery | Neoplasms - drug therapy | Animals | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Angiogenesis Inhibitors - therapeutic use | Receptor, TIE-2 - metabolism | Angiopoietin-2 - antagonists & inhibitors | Neoplasms - pathology | Angiogenesis Inhibitors - adverse effects | Vascular endothelial growth factor | Diabetic retinopathy | Phosphorylation | Colorectal cancer | FDA approval | Permeability | Metastasis | Kinases | Cancer therapies | Clinical outcomes | Liver cancer | Thyroid cancer | Conflicts of interest | Ligands | Tumors
Journal Article
Turkish Journal of Hematology, ISSN 1300-7777, 2010, Volume 27, Issue 4, pp. 282 - 288
Journal Article
SpringerPlus, ISSN 2193-1801, 12/2016, Volume 5, Issue 1, pp. 1518 - 11
Objective: The aim of this study was to investigate the effects of docosahexaenoic acid (DHA) on the generation of angiopoietin-2 (Ang-2) by rat brain... 
Ang-2 | OGD environment | COX-2 | DHA | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | BARRIER | INJURY | SUPPLEMENTATION | IN-VIVO | SUBARACHNOID HEMORRHAGE | GROWTH-FACTOR | EXPRESSION
Journal Article
American Journal of Translational Research, ISSN 1943-8141, 2019, Volume 11, Issue 3, pp. 1895 - 1907
The fate of neural stem cells (NSCs) is decided by numerous growth factors. Among these factors, the well-known angiogenic factor angiopoietin-2 (Ang-2) has... 
Ang-2 | Neuronal differentiation | Rapamycin | MTOR | Neural stem cell | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | VALPROIC ACID | SUBVENTRICULAR ZONE | neuronal differentiation | STIMULATES NEUROGENESIS | IN-VITRO | NEURITE OUTGROWTH | PI3K | ONCOLOGY | ENDOTHELIAL-CELLS | GROWTH-FACTORS | mTOR | NEURAL PROGENITOR CELLS | rapamycin
Journal Article