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2006, ISBN 9780470012949, xvii, 350 p., [8] p. of plates
Book
Expert review of anticancer therapy, ISSN 1473-7140, 02/2004, Volume 4, Issue 1, pp. 105 - 128
Brain tumors are a diverse group of malignancies that remain refractory to conventional treatment approaches. Molecular neuro-oncology has now begun to clarify... 
PI3K | signal transduction | angiogenesis | neuro-oncology | mTOR | PTEN | brain tumor | molecular | Akt | SHH/PTCH | Brain tumor | Angiogenesis | Signal transduction | Neuro-oncology | Molecular | Protein Kinases - metabolism | Molecular Biology | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Receptors, Cell Surface | Brain Neoplasms - blood supply | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Drug Delivery Systems | Hedgehog Proteins | PTEN Phosphohydrolase | Drug Design | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Angiogenesis Inhibitors - therapeutic use | Membrane Proteins - metabolism | Patched Receptors | Protein-Serine-Threonine Kinases - metabolism | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Suppressor Proteins - metabolism | Signal Transduction | Enzyme Inhibitors - pharmacology | Angiogenesis Inhibitors - pharmacology | Brain Neoplasms - drug therapy | Enzyme Inhibitors - therapeutic use | Proto-Oncogene Proteins c-akt | Medical Oncology | Protein Kinase Inhibitors | Membrane Proteins - antagonists & inhibitors | Neovascularization, Pathologic - drug therapy | Trans-Activators - metabolism | TOR Serine-Threonine Kinases | Trans-Activators - antagonists & inhibitors | Phosphoric Monoester Hydrolases - metabolism | Patched-1 Receptor | Care and treatment | Brain tumors | Patient outcomes | Development and progression | Genetic aspects | Cellular signal transduction | Research | Gene therapy | Health aspects | Index Medicus
Journal Article
Journal Article
Journal of cellular biochemistry, ISSN 1097-4644, 07/2009, Volume 107, Issue 4, pp. 600 - 608
Journal Article
2009, ISBN 1402095635, ix, 125
In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor... 
Neovascularization | Blood-vessels | Growth | Neovascularization inhibitors | Tumors | Treatment | Pathology | History of Science | Biomedicine | Cancer Research | Oncology | Biomedical and Life Sciences | Cell Biology
Book
Journal of Clinical Oncology, ISSN 0732-183X, 02/2010, Volume 28, Issue 5, pp. 780 - 787
Journal Article
Journal Article