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Cancer immunology, immunotherapy, ISSN 1432-0851, 11/2008, Volume 58, Issue 7, pp. 1033 - 1045
Lenalidomide (Revlimid┬«; CC-5013) and pomalidomide (CC-4047) are IMiDs┬« proprietary drugs having immunomodulatory properties that have both shown activity in... 
Immunomodulatory drugs | Biomedicine | Immunology | Lenalidomide | T regulatory cells | Cancer Research | Oncology | Pomalidomide | IMiDs | Life Sciences & Biomedicine | Science & Technology | Forkhead Transcription Factors - immunology | Receptors, Nerve Growth Factor - immunology | Receptors, Transforming Growth Factor beta - immunology | Receptors, Nerve Growth Factor - drug effects | Humans | Receptors, Nerve Growth Factor - metabolism | Thalidomide - pharmacology | Colonic Neoplasms - metabolism | Receptors, OX40 - immunology | T-Lymphocytes, Regulatory - immunology | Thalidomide - analogs & derivatives | Receptors, OX40 - metabolism | Transforming Growth Factor beta - drug effects | Colonic Neoplasms - immunology | Forkhead Transcription Factors - metabolism | Interleukin-10 - metabolism | Female | Antineoplastic Agents - pharmacology | Forkhead Transcription Factors - antagonists & inhibitors | Immunosuppressive Agents - pharmacology | Receptors, Tumor Necrosis Factor - metabolism | Transforming Growth Factor beta - immunology | Glucocorticoid-Induced TNFR-Related Protein | T-Lymphocytes, Regulatory - drug effects | Animals | Receptors, Transforming Growth Factor beta - drug effects | Receptors, Transforming Growth Factor beta - metabolism | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Receptors, Tumor Necrosis Factor - immunology | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Receptors, Tumor Necrosis Factor - drug effects | Receptors, OX40 - antagonists & inhibitors | Care and treatment | Dexamethasone | Multiple myeloma | Angiogenesis inhibitors | Transforming growth factors | T cells | Cancer | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 04/2010, Volume 464, Issue 7291, pp. 1052 - 1057
.... Although -secretase inhibitors (GSIs) have progressed into the clinic, GSIs... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Angiogenesis Inhibitors - immunology | Neoplasms - metabolism | NIH 3T3 Cells | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Receptor, Notch2 - antagonists & inhibitors | Receptors, Notch - metabolism | Humans | Goblet Cells - drug effects | Receptors, Notch - genetics | Peptide Library | Receptors, Notch - antagonists & inhibitors | Antibody Specificity - immunology | Angiogenesis Inhibitors - therapeutic use | Antibodies - immunology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Antibodies - therapeutic use | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Angiogenesis Inhibitors - pharmacology | Receptor, Notch1 - immunology | Neoplasms - blood supply | Receptor, Notch2 - immunology | Antibodies - adverse effects | Neoplasms - drug therapy | Antibodies - pharmacology | Animals | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Goblet Cells - pathology | Receptor, Notch1 - antagonists & inhibitors | Neoplasms - pathology | Receptors, Notch - immunology | Viral antibodies | Proteases | Proteolysis | Physiological aspects | Antibodies | Research | Properties | Membrane proteins | Cell growth | Cell cycle | Cancer | Crystal structure | Apoptosis | Receptors | Inhibitors | Toxicity | Notches | Mathematical models | Inhibition | Signalling | Diseases | Index Medicus
Journal Article
Seminars in immunopathology, ISSN 1863-2297, 1/2012, Volume 34, Issue 1, pp. 73 - 91
Sphingosine 1-phosphate (S1P) is a lipid mediator produced from sphingomyelin by the sequential enzymatic actions of sphingomyelinase, ceramidase, and... 
Biomedicine | Immunology | Vascular barrier integrity | G-protein-coupled receptor | Coagulation | Immune cell trafficking | Internal Medicine | Inflammation | Sphingosine 1-phosphate | Pathology | Life Sciences & Biomedicine | Science & Technology | Inflammation - pathology | Receptors, Lysosphingolipid - antagonists & inhibitors | Lymph Nodes - pathology | Multiple Sclerosis - blood | Humans | Immunosuppressive Agents - therapeutic use | Tumor Necrosis Factor-alpha - blood | Inflammation - blood | Lysophospholipids - immunology | Neovascularization, Pathologic - blood | Neovascularization, Pathologic - pathology | Signal Transduction - immunology | Neoplasm Metastasis | Lymphocytes - immunology | Neoplasms - blood | Blood Coagulation - immunology | Inflammation - drug therapy | Propylene Glycols - therapeutic use | Tumor Necrosis Factor-alpha - immunology | Neovascularization, Pathologic - immunology | Receptors, Lysosphingolipid - metabolism | Lymphocytes - metabolism | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Atherosclerosis - immunology | Fingolimod Hydrochloride | Lymph Nodes - metabolism | Sphingosine - immunology | Inflammation - immunology | Lysophospholipids - blood | Lymph Nodes - immunology | Neoplasms - drug therapy | Atherosclerosis - blood | Receptors, Lysosphingolipid - immunology | Lymphocytes - pathology | Sphingosine - analogs & derivatives | Animals | Signal Transduction - drug effects | Neoplasms - immunology | Neovascularization, Pathologic - drug therapy | Multiple Sclerosis - immunology | Sphingosine - blood | Sphingosine - therapeutic use | Neoplasms - pathology | Multiple Sclerosis - drug therapy | Enzymes | Multiple sclerosis | Lymphocytes | Sphingosine | Atherosclerosis | Metastasis | Index Medicus | G protein-coupled receptors | sphingosine kinase | Central nervous system | Lipids | Cell surface | Ceramidase | Blood | Lymph nodes | Metastases | Sphingomyelin phosphodiesterase | Angiogenesis | Tumor necrosis factor | Arteriosclerosis | FTY720 | sphingomyelin | Lymph
Journal Article
Current pharmaceutical design, ISSN 1381-6128, 2013, Volume 19, Issue 28, pp. 5105 - 5120
Journal Article
CA: a cancer journal for clinicians, ISSN 0007-9235, 09/2012, Volume 62, Issue 5, pp. 309 - 335
Journal Article