X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (8255) 8255
Publication (854) 854
Book Review (201) 201
Newsletter (192) 192
Newspaper Article (154) 154
Book Chapter (73) 73
Book / eBook (10) 10
Conference Proceeding (9) 9
Dissertation (7) 7
Magazine Article (7) 7
Trade Publication Article (4) 4
Transcript (4) 4
Data Set (3) 3
Report (3) 3
Reference (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (5639) 5639
index medicus (5139) 5139
angiogenesis (4878) 4878
animals (3385) 3385
oncology (3053) 3053
cancer (2803) 2803
female (2460) 2460
male (2298) 2298
endothelial growth-factor (1870) 1870
mice (1779) 1779
vascular endothelial growth factor (1725) 1725
angiogenesis inhibitors - therapeutic use (1665) 1665
bevacizumab (1552) 1552
pharmacology & pharmacy (1508) 1508
angiogenesis inhibitors (1468) 1468
tumors (1384) 1384
middle aged (1226) 1226
care and treatment (1208) 1208
chemotherapy (1184) 1184
aged (1170) 1170
research (1141) 1141
metastasis (1134) 1134
angiogenesis inhibitors - pharmacology (1060) 1060
cell line, tumor (998) 998
treatment outcome (961) 961
angiogenesis inhibitors - administration & dosage (944) 944
neoplasms - drug therapy (931) 931
analysis (930) 930
apoptosis (922) 922
adult (910) 910
medicine & public health (888) 888
expression (879) 879
antineoplastic agents - therapeutic use (877) 877
therapy (851) 851
vascular endothelial growth factor a - antagonists & inhibitors (793) 793
pharmacokinetics (785) 785
cancer therapies (765) 765
vegf (757) 757
health aspects (756) 756
neovascularization, pathologic - drug therapy (756) 756
ophthalmology (739) 739
drug therapy (722) 722
clinical trials (713) 713
antineoplastic agents - pharmacology (700) 700
angiogenesis inhibitors - pharmacokinetics (659) 659
in-vivo (646) 646
rats (639) 639
proteins (631) 631
cell proliferation - drug effects (611) 611
kinases (608) 608
tumor angiogenesis (603) 603
article (597) 597
growth (597) 597
medicine (593) 593
antineoplastic agents (581) 581
mice, nude (570) 570
dose-response relationship, drug (562) 562
angiogenesis inhibitors - adverse effects (555) 555
antimitotic agents (552) 552
neovascularization (548) 548
studies (545) 545
research article (524) 524
cells (521) 521
macular degeneration (511) 511
inhibition (510) 510
physiological aspects (506) 506
tyrosine kinase inhibitor (505) 505
in-vitro (500) 500
xenograft model antitumor assays (499) 499
antineoplastic combined chemotherapy protocols - therapeutic use (490) 490
biochemistry & molecular biology (485) 485
aged, 80 and over (477) 477
cell biology (477) 477
breast-cancer (472) 472
vascular endothelial growth factor a - metabolism (472) 472
pharmacology/toxicology (462) 462
antibodies, monoclonal, humanized (455) 455
breast cancer (447) 447
cancer research (447) 447
medical research (447) 447
pharmacology (440) 440
clinical trials as topic (422) 422
review (422) 422
apoptosis - drug effects (420) 420
ranibizumab (417) 417
tumor-growth (416) 416
disease models, animal (414) 414
drugs (403) 403
multidisciplinary sciences (402) 402
solid tumors (402) 402
antitumor-activity (394) 394
development and progression (394) 394
antibodies, monoclonal - therapeutic use (393) 393
signal transduction (393) 393
hematology (386) 386
medicine, research & experimental (386) 386
intravitreal injections (385) 385
antineoplastic agents - administration & dosage (382) 382
rodents (382) 382
drug delivery systems (380) 380
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8642) 8642
French (17) 17
German (15) 15
Spanish (7) 7
Japanese (5) 5
Chinese (3) 3
Korean (2) 2
Polish (2) 2
Russian (2) 2
Hungarian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Ophthalmology, ISSN 0161-6420, 2007, Volume 114, Issue 5, pp. 855 - 859
Journal Article
Progress in Retinal and Eye Research, ISSN 1350-9462, 03/2017, Volume 57, pp. 134 - 185
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 01/2008, Volume 68, Issue 1, pp. 206 - 215
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2007, Volume 6, Issue 7, pp. 2012 - 2021
With the development of targeted therapeutics, especially for small-molecule inhibitors, it is important to understand whether the observed in vivo efficacy... 
kinase inhibitor | Pharmacodynamics | pazopanib | angiogenesis | VEGF | TARGET | ONCOLOGY | FACTOR RECEPTORS | EXPRESSION | CANCER | TUMORS | RENAL-CELL CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | Pyrimidines - blood | Humans | Fibroblast Growth Factor 2 - pharmacology | Antineoplastic Agents - administration & dosage | Indazoles - administration & dosage | Sulfones - pharmacology | Neovascularization, Pathologic - pathology | Phosphotyrosine - metabolism | Dose-Response Relationship, Drug | Sulfonamides - blood | Inhibitory Concentration 50 | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Cornea - pathology | Phosphorylation - drug effects | Sulfones - blood | Vascular Endothelial Growth Factor A - pharmacology | Protein Kinase Inhibitors - pharmacokinetics | Pyrimidines - administration & dosage | Pyrimidines - pharmacology | Sulfones - pharmacokinetics | Sulfonamides - pharmacology | Protein Kinase Inhibitors - blood | Sulfonamides - pharmacokinetics | Indazoles - pharmacology | Protein Kinase Inhibitors - administration & dosage | Indazoles - blood | Animals | Indazoles - pharmacokinetics | Cell-Free System | Mice, Nude | Antineoplastic Agents - blood | Cell Line, Tumor | Pyrimidines - pharmacokinetics | Mice | Protein Kinase Inhibitors - pharmacology | Sulfonamides - administration & dosage | Sulfones - administration & dosage
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2010, Volume 28, Issue 5, pp. 780 - 787
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2011, Volume 54, Issue 20, pp. 7066 - 7083
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2009, Volume 15, Issue 5, pp. 1612 - 1622
Purpose: Comparison of the antiangiogenic/vascular properties of the oral mammalian target of rapamycin (mTOR) inhibitor RAD001 (everolimus) and the vascular... 
pharmacokinetics | DCE-MRI | RAD001 | angiogenesis | PTK/ZK | MAMMALIAN TARGET | FACTOR-RECEPTOR | RAPAMYCIN | ANGIOGENESIS | ONCOLOGY | IN-VIVO | MAGNETIC-RESONANCE | CELL-PROLIFERATION | OVARIAN-CANCER | TUMOR VASCULATURE | ENDOTHELIAL GROWTH-FACTOR | Protein Kinases - metabolism | Phthalazines - pharmacokinetics | Humans | Protein Kinases - chemistry | Pyridines - pharmacokinetics | Transplantation, Heterologous | Vascular Endothelial Growth Factor A - metabolism | Immunoenzyme Techniques | Tissue Distribution | Rats, Inbred BN | Receptors, Vascular Endothelial Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Female | Receptor, TIE-2 - metabolism | Everolimus | Rats, Inbred WF | Protein Kinase Inhibitors - pharmacokinetics | Sirolimus - analogs & derivatives | Mice, Inbred C57BL | Angiogenesis Inhibitors - pharmacology | Rats | Angiogenesis Inhibitors - pharmacokinetics | Sirolimus - pharmacokinetics | Sirolimus - pharmacology | Cell Movement - drug effects | Magnetic Resonance Imaging | Phthalazines - pharmacology | Animals | Neovascularization, Pathologic - drug therapy | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | TOR Serine-Threonine Kinases | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Neoplasms, Experimental - blood supply
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 08/2015, Volume 9, pp. 4479 - 4499
Transforming growth factor-beta (TGF-beta) signaling regulates a wide range of biological processes. TGF-beta plays an important role in tumorigenesis and... 
LY2157299 | Clinical trials | TGF-β | TGF-βRI kinase inhibitor | ALK5 | Galunisertib | Cancer | CHEMISTRY, MEDICINAL | RECEPTOR-TYPE-II | MESENCHYMAL TRANSITION | BREAST-CANCER | TGF-beta | HEPATOCELLULAR-CARCINOMA | TGF-beta RI kinase inhibitor | PLASMA-LEVELS | THERAPEUTIC TARGET | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | cancer | clinical trials | TUMOR-GROWTH | galunisertib | I KINASE INHIBITOR | Phosphorylation | Pyrazoles - therapeutic use | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Molecular Targeted Therapy | Quinolines - administration & dosage | Quinolines - pharmacokinetics | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Antineoplastic Agents - adverse effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacokinetics | Molecular Structure | Heart Diseases - chemically induced | Pyrazoles - pharmacokinetics | Protein-Serine-Threonine Kinases - metabolism | Pyrazoles - adverse effects | Protein Kinase Inhibitors - pharmacokinetics | Drug Administration Schedule | Administration, Oral | Quinolines - chemistry | Smad2 Protein - metabolism | Neoplasms - enzymology | Treatment Outcome | Antineoplastic Agents - chemistry | Drug Discovery | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Quinolines - therapeutic use | Neoplasms - pathology | Quinolines - adverse effects | Antimitotic agents | Cellular signal transduction | Transforming growth factors | Antineoplastic agents | Health aspects | Testing | Animal models | Transcription factors | Laboratories | Toxicity | Transforming growth factor-b | Oligonucleotides | Glioblastoma | Hepatocellular carcinoma | Metastasis | Vaccines | Kinases | Drug resistance | Cancer therapies | Anticancer properties | Metastases | Proteins | Angiogenesis | Signal transduction | Pancreatic carcinoma | Smad2 protein | Fibroblasts | Physiology | Tumorigenesis | Colon | Growth factors | Dosing | Cytokines | Melanoma | Antisense oligonucleotides | Immunosurveillance | Pharmacology | Breast cancer | Lung carcinoma | Patients | Biological activity | Signaling | Inhibitors | Pancreatic cancer | Monoclonal antibodies | Ligands | Antitumor activity | Prostate cancer | Tumors
Journal Article