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Drug Safety, ISSN 0114-5916, 06/2013, Volume 36, Issue 6, pp. 413 - 426
Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of certain forms of cancers, raising hopes for many patients with otherwise unresponsive... 
FACTOR RECEPTOR INHIBITORS | THYROID-DYSFUNCTION | INDUCED SKIN RASH | DOSE-ESCALATION | SELECTIVE INHIBITOR | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CANCER-PATIENTS | CUTANEOUS TOXICITIES | SUNITINIB INDUCES HYPOTHYROIDISM | ANGIOGENESIS INHIBITORS | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Neoplasms - metabolism | Protein-Tyrosine Kinases - metabolism | Skin - metabolism | Humans | Endothelium, Vascular - drug effects | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Endothelium, Vascular - enzymology | Neoplasm Proteins - metabolism | Dose-Response Relationship, Drug | Receptor, Epidermal Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Antineoplastic Agents - adverse effects | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Biomarkers - metabolism | Risk Assessment | Neoplasms - enzymology | Evidence-Based Medicine | Skin - enzymology | Neoplasms - drug therapy | Protein Kinase Inhibitors - administration & dosage | Endothelium, Vascular - metabolism | Protein Kinase Inhibitors - therapeutic use | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Skin - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors | Hypertension | Enzymes | Kinases | Hypothyroidism | Proteins | Angiogenesis | Epidermal growth factor | Biomarkers | Ligands | Skin | Pharmaceutical industry | Drug dosages | Cancer | Index Medicus
Journal Article
Journal Article
Journal of the American Society of Hypertension, ISSN 1933-1711, 06/2018, Volume 12, Issue 6, pp. 409 - 425
The vascular endothelial growth factor (VEGF) signaling pathway (VSP) fulfills a cardinal role in endothelial cells and its inhibition has profound... 
cardiovascular events | Angiogenesis inhibitors | chemotherapy | hypertension | ANGIOTENSIN SYSTEM INHIBITORS | DEPENDENT VASODILATION | RENAL-CELL CARCINOMA | BLOOD-PRESSURE | CANCER-PATIENTS | METASTATIC CARCINOMA | NITRIC-OXIDE | THROMBOEMBOLIC EVENTS | PERIPHERAL VASCULAR DISEASE | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2008, Volume 26, Issue 22, pp. 3709 - 3714
Journal Article
Neurology, ISSN 0028-3878, 03/2008, Volume 70, Issue 10, pp. 779 - 787
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 08/2014, Volume 8, pp. 1107 - 1123
Background: Anti-angiogenic therapy in certain cancers has been associated with improved control of tumor growth and metastasis. Development of anti-angiogenic... 
Zebrafish toxicity assay | Therapeutic window | Angiogenesis | VEGFR inhibitors | CHEMISTRY, MEDICINAL | COMBRETASTATIN A-4 PHOSPHATE | angiogenesis | PHASE-III | METABOLIC-ACTIVATION | RENAL-CELL CARCINOMA | CHICK CHORIOALLANTOIC MEMBRANE | SELECTIVE INHIBITOR | ANTIANGIOGENIC ACTIVITY | RECEPTOR TYROSINE KINASES | therapeutic window | zebrafish toxicity assay | IN-VIVO | PHARMACOLOGY & PHARMACY | ENDOTHELIAL GROWTH-FACTOR | Angiogenesis Inhibitors - pharmacology | Neoplasms - blood supply | Lethal Dose 50 | Zebrafish - embryology | Neoplasms - drug therapy | Neovascularization, Pathologic - pathology | Angiogenesis Inhibitors - administration & dosage | Animals | Angiogenesis Inhibitors - toxicity | Neovascularization, Pathologic - drug therapy | Drug Design | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Models, Animal | Toxicity Tests - methods | Cell Proliferation - drug effects | Translational Medical Research - methods | Drugs | Physiological aspects | Angiogenesis inhibitors | Research | Health aspects | Zebra fish | Cell proliferation | Toxicity | Kinases | Cancer therapies | Metastases | Cell adhesion & migration | Cell growth | Prediction models | Antiangiogenic agents | Chemical activity | Mathematical models | Vascular endothelial growth factor | Growth factors | Drug dosages | Edema | Phenotypes | Translation | Effectiveness | Blood vessels | Zebrafish | Embryos | Biological activity | Endothelial cells | Vascular endothelial growth factor receptors | Organic chemistry | Inhibitors | Antiangiogenics | Morphology | Kidney cancer | Drug discovery
Journal Article