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Journal Article
Brain (London, England : 1878), ISSN 1460-2156, 06/2012, Volume 135, Issue 6, pp. 1964 - 1980
Ambivalent effects of interleukin-6 on the pathogenesis of ischaemic stroke have been reported. However, to date, the long-term actions of interleukin-6 after... 
cerebral ischaemia | inflammation | regeneration | angiogenesis | interleukin-6 | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Angiogenic Proteins - genetics | Infarction, Middle Cerebral Artery - physiopathology | Oligonucleotide Array Sequence Analysis | Cytokine Receptor gp130 - genetics | Embryo, Mammalian | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Receptor, trkB - genetics | Bone Marrow Transplantation - methods | Infarction, Middle Cerebral Artery - complications | Perfusion Imaging | Cytokines - genetics | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Disease Models, Animal | Cytokine Receptor gp130 - metabolism | Interleukin-6 - genetics | Endothelin-1 - genetics | Hypoxia - complications | Signal Transduction - genetics | Analysis of Variance | Brain - pathology | Mice | Neovascularization, Pathologic - metabolism | Endothelial Cells - pathology | Angiogenic Proteins - metabolism | Gait Disorders, Neurologic - etiology | Mice, Knockout - genetics | Cerebral Cortex - cytology | Neovascularization, Pathologic - etiology | Tetrazolium Salts | Thiazoles | Microfilament Proteins - metabolism | Neurons - drug effects | STAT3 Transcription Factor - metabolism | Calcium-Binding Proteins - metabolism | Green Fluorescent Proteins - metabolism | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Endothelin-1 - metabolism | Gene Expression Regulation - genetics | Cells, Cultured | Neuroglia - physiology | Infarction, Middle Cerebral Artery - pathology | Glucose - deficiency | Rotarod Performance Test | Animals | Infarction, Middle Cerebral Artery - surgery | Signal Transduction - physiology | Receptor, trkB - metabolism | Index Medicus | Abridged Index Medicus | Original
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 02/2014, Volume 34, Issue 2, pp. 285 - 293
.... As such succinate readily increases, exerting its biological effects via a specific receptor, G-protein... 
animals newborn | succinic acid | GPR91 protein mouse | hypoxia-ischemia brain | intracellular signaling peptides and proteins | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Receptors, G-Protein-Coupled - metabolism | Succinic Acid - administration & dosage | Astrocytes - pathology | Cerebral Cortex - pathology | Injections, Intraventricular | Neuroprotective Agents - metabolism | Hypoxia-Ischemia, Brain - etiology | Cerebral Infarction - physiopathology | Neuroprotective Agents - pharmacology | Time Factors | Neurons - metabolism | Cerebral Cortex - drug effects | Disease Models, Animal | Animals, Newborn | Endothelial Cells - metabolism | Mice, Knockout | Dinoprostone - metabolism | Signal Transduction - drug effects | Succinic Acid - metabolism | Cerebral Infarction - etiology | Mice | Receptors, G-Protein-Coupled - genetics | Endothelial Cells - pathology | Angiogenic Proteins - metabolism | Astrocytes - metabolism | Cerebral Infarction - drug therapy | Neovascularization, Physiologic - drug effects | Neurons - pathology | Cerebral Cortex - blood supply | Hypoxia-Ischemia, Brain - pathology | Receptors, G-Protein-Coupled - agonists | Cerebral Infarction - genetics | Hypoxia-Ischemia, Brain - genetics | Cerebral Cortex - metabolism | Cerebral Infarction - metabolism | Prostaglandin Antagonists - pharmacology | Neurons - drug effects | Neuroprotective Agents - administration & dosage | Hypoxia-Ischemia, Brain - metabolism | Receptors, Prostaglandin E, EP4 Subtype - drug effects | Cerebral Infarction - pathology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Astrocytes - drug effects | Cell Line | Tissue Culture Techniques | Mice, Inbred C57BL | Hypoxia-Ischemia, Brain - drug therapy | Cyclooxygenase Inhibitors - pharmacology | Animals | Succinic Acid - pharmacology | Endothelial Cells - drug effects | Hypoxia-Ischemia, Brain - physiopathology | Index Medicus
Journal Article
The Journal of neuroscience, ISSN 0270-6474, 04/2013, Volume 33, Issue 16, pp. 6974 - 6978
.... By restricting the Rac1-guanine nucleotide exchange factor Tiam1 to spines, the polarity protein Par3 promotes synapse development by spatially controlling Rac1 activation... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Disks Large Homolog 4 Protein | Angiogenic Proteins - genetics | Electric Stimulation | Cadherins - metabolism | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Humans | Rats, Long-Evans | Actins - metabolism | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Nerve Growth Factors - metabolism | Neoplasm Proteins - metabolism | Brain - metabolism | Synapses - metabolism | Transfection | Guanine Nucleotide Exchange Factors - metabolism | Brain - ultrastructure | Neurons - physiology | Membrane Proteins - metabolism | Imaging, Three-Dimensional | T-Lymphoma Invasion and Metastasis-inducing Protein 1 | Excitatory Postsynaptic Potentials - genetics | Vesicular Glutamate Transport Protein 1 - metabolism | Cells, Cultured | Receptors, G-Protein-Coupled | Rats | Electroporation | Nerve Tissue Proteins | Hippocampus - cytology | Mutation - genetics | Cell Adhesion Molecules - metabolism | Cell Polarity - genetics | Microscopy, Confocal | Patch-Clamp Techniques | Animals | Carrier Proteins - metabolism | Analysis of Variance | Angiogenic Proteins - metabolism | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 04/2016, Volume 113, Issue 16, pp. 4476 - 4481
Inhibition of the vascular endothelial growth factor (VEGF) pathway has failed to improve overall survival of patients with glioblastoma (GBM). We previously... 
Anti-angiogenic therapy | Macrophage polarization | Tumor microenvironment | Microglia reprogramming | Anti-tumor immunity | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Macrophages - pathology | Antibodies, Bispecific - pharmacology | Vesicular Transport Proteins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neoplasms, Experimental - pathology | Xenograft Model Antitumor Assays | Macrophages - metabolism | Vesicular Transport Proteins - antagonists & inhibitors | Animals | Antibodies, Neoplasm - pharmacology | Ribonuclease, Pancreatic - metabolism | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Mice | Neoplasms, Experimental - metabolism | Glioblastoma - drug therapy | Ribonuclease, Pancreatic - antagonists & inhibitors | Neoplasms, Experimental - drug therapy | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Models | Macrophages | Vascular endothelial growth factor | Health aspects | Glioblastoma multiforme | Genotype & phenotype | Survival analysis | Protein expression | Cells | Tumors | Cancer | Index Medicus | Biological Sciences | anti-angiogenic therapy | macrophage polarization | tumor microenvironment | microglia reprogramming | anti-tumor immunity
Journal Article
Endocrine, ISSN 1355-008X, 2/2013, Volume 43, Issue 1, pp. 147 - 153
... of proteins involved in the control of vascular proliferation, including the vascular endothelial growth factor (VEGF... 
eNOS | Thyroid toxic adenomas | Medicine & Public Health | TSH receptor mutations | VEGF | PDGF | Internal Medicine | Diabetes | Endocrinology | Science, general | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Angiogenic Proteins - genetics | Up-Regulation | Cell Proliferation | Humans | Microvessels - metabolism | Microvessels - pathology | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Goiter, Nodular - metabolism | Platelet-Derived Growth Factor - biosynthesis | Goiter, Nodular - pathology | Lymphatic System - metabolism | Thyroid Gland - immunology | Neoplasm Proteins - genetics | Angiogenic Proteins - biosynthesis | Biomarkers - metabolism | Receptors, Platelet-Derived Growth Factor - genetics | Receptors, Thyrotropin - immunology | Nitric Oxide Synthase Type III - genetics | Receptors, Thyrotropin - deficiency | Thyrotoxicosis - immunology | Receptors, Platelet-Derived Growth Factor - metabolism | Thyroid Gland - pathology | Lymphatic System - immunology | Neovascularization, Pathologic - metabolism | Mutation | Thyroid Gland - metabolism | Angiogenic Proteins - metabolism | Goiter, Nodular - immunology | Vascular Endothelial Growth Factor A - biosynthesis | Receptors, Thyrotropin - genetics | Lymphatic System - pathology | Nitric Oxide Synthase Type III - biosynthesis | Thyrotoxicosis - metabolism | Neoplasm Proteins - metabolism | Platelet-Derived Growth Factor - genetics | Neovascularization, Pathologic - pathology | Protein Isoforms - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Thyroid Gland - blood supply | Goiter, Nodular - physiopathology | Nitric Oxide Synthase Type III - metabolism | Receptors, Vascular Endothelial Growth Factor - genetics | Thyrotoxicosis - physiopathology | Thyrotoxicosis - pathology | Neoplasm Proteins - biosynthesis | Receptors, Thyrotropin - metabolism | Receptors, Vascular Endothelial Growth Factor - biosynthesis | Platelet-Derived Growth Factor - metabolism | Protein Isoforms - biosynthesis | Receptors, Platelet-Derived Growth Factor - biosynthesis | Protein Isoforms - genetics | Hormone receptors | Thyroid cancer | Gene mutations | Physiological aspects | Genetic aspects | Research | Health aspects | Vascular endothelial growth factor | Risk factors | Index Medicus
Journal Article