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The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 12, pp. 1123 - 1133
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 16, pp. 2054 - 2063
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 3, pp. 211 - 221
Loss-of-function variants in ANGPTL3 were associated with lower plasma levels of lipids and lower rates of coronary disease. A monoclonal antibody against... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | IMMUNOGLOBULIN GENES | ATHEROSCLEROSIS | RISK | CORONARY-ARTERY-DISEASE | FAMILIAL COMBINED HYPOLIPIDEMIA | LIPOPROTEIN-LIPASE GENE | TRANSGENIC MICE | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Angiopoietins - antagonists & inhibitors | Dose-Response Relationship, Drug | Dyslipidemias - blood | Angiopoietin-like Proteins | Lipids - blood | Female | Disease Models, Animal | Dyslipidemias - drug therapy | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Coronary Artery Disease - metabolism | Mice, Inbred Strains | Atherosclerosis - metabolism | Animals | Antibodies, Monoclonal - administration & dosage | Coronary Artery Disease - genetics | Lipid Metabolism - drug effects | Aged | Mice | Mutation | Angiopoietins - genetics | Cholesterol, LDL | Research | Antibiosis | Atherosclerosis | Lipoproteins (low density) | Medical research | Angiopoietin | Genomics | Genes | Coronary artery | Triglycerides | Biochemistry | Gene expression | Cholesterol | Serum levels | Proteins | Antagonism | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Heart diseases | Drug dosages | Pharmaceuticals
Journal Article
by Stitziel, Nathan O and Stirrups, Kathleen E and Masca, Nicholas G. D and Erdmann, Jeanette and Ferrario, Paola G and König, Inke R and Weeke, Peter E and Webb, Thomas R and Auer, Paul L and Schick, Ursula M and Lu, Yingchang and Zhang, He and Dube, Marie-Pierre and Goel, Anuj and Farrall, Martin and Peloso, Gina M and Won, Hong-Hee and Do, Ron and van Iperen, Erik and Kanoni, Stavroula and Kruppa, Jochen and Mahajan, Anubha and Scott, Robert A and Willenborg, Christina and Braund, Peter S and van Capelleveen, Julian C and Doney, Alex S. F and Donnelly, Louise A and Asselta, Rosanna and Merlini, Piera A and Duga, Stefano and Marziliano, Nicola and Denny, Josh C and Shaffer, Christian M and El-Mokhtari, Nour Eddine and Franke, Ane and Gottesman, Omri and Heilmann, Stefanie and Hengstenberg, Christian and Hoffmann, Per and Holmen, Oddgeir L and Hveem, Kristian and Jansson, Jan-Håkan and Jöckel, Karl-Heinz and Kessler, Thorsten and Kriebel, Jennifer and Laugwitz, Karl L and Marouli, Eirini and Martinelli, Nicola and McCarthy, Mark I and van Zuydam, Natalie R and Meisinger, Christa and Esko, Tõnu and Mihailov, Evelin and Escher, Stefan A and Alver, Maris and Moebus, Susanne and Morris, Anew D and Müller-Nurasyid, Martina and Nikpay, Majid and Olivieri, Oliviero and Perreault, Louis-Philippe Lemieux and AlQarawi, Alaa and Robertson, Neil R and Akinsanya, Karen O and Reilly, Dermot F and Vogt, Thomas F and Yin, Wu and Asselbergs, Folkert W and Kooperberg, Charles and Jackson, Rebecca D and Stahl, Eli and Strauch, Konstantin and Varga, Tibor V and Waldenberger, Melanie and Zeng, Lingyao and Kraja, Aldi T and Liu, Chunyu and Ehret, Georg B and Newton-Cheh, Christopher and Chasman, Daniel I and Chowdhury, Rajiv and Ferrario, Marco and Ford, Ian and Jukema, J. Wouter and Kee, Frank and Kuulasmaa, Kari and Nordestgaard, Børge G and Perola, Markus and Saleheen, Danish and Sattar, Naveed and Surenan, Praveen and Tregouet, David and Young, Robin and Howson, Joanna M. M and Butterworth, Adam S and Danesh, John and Ardissino, Diego and Bottinger, Erwin P and Erbel, Raimund and ... and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 12, pp. 1134 - 1144
Journal Article
Oncogene, ISSN 0950-9232, 10/2013, Volume 32, Issue 44, pp. 5241 - 5252
Journal Article