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1. Full Text The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes
by Schoenherr, Christina and Byron, Adam and Griffith, Billie and Loftus, Alexander and Wills, Jimi C and Munro, Alison F and von Kriegsheim, Alex and Frame, Margaret C
The Journal of biological chemistry, ISSN 0021-9258, 08/2020, Volume 295, Issue 34, pp. 12045 - 12057
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Chromatin - metabolism | Focal Adhesion Kinase 1 - genetics | Transforming Growth Factor beta3 - genetics | Humans | Multiprotein Complexes - genetics | Activating Transcription Factor 2 - genetics | A Kinase Anchor Proteins - genetics | Multiprotein Complexes - metabolism | Nuclear Proteins - genetics | Active Transport, Cell Nucleus - genetics | DNA Helicases - genetics | Focal Adhesion Kinase 1 - metabolism | A Kinase Anchor Proteins - metabolism | Angiopoietin-1 - biosynthesis | Cell Line | Signal Transduction | Integrin beta Chains - biosynthesis | Gene Expression Regulation | Nuclear Proteins - metabolism | Transcription Factors - genetics | Activating Transcription Factor 2 - metabolism | Transforming Growth Factor beta2 - biosynthesis | Transcription Factors - metabolism | Angiopoietin-1 - genetics | DNA Helicases - metabolism | Adaptor Proteins, Signal Transducing - genetics | Integrin alpha Chains - biosynthesis | Integrin beta Chains - genetics | Transforming Growth Factor beta2 - genetics | Adaptor Proteins, Signal Transducing - metabolism | Transforming Growth Factor beta3 - biosynthesis | Chromatin - genetics | Integrin alpha Chains - genetics | Index Medicus
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2. Full Text DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells
by Banerjee, Saswati and Bacanamwo, Methode
Experimental cell research, ISSN 0014-4827, 2010, Volume 316, Issue 2, pp. 172 - 180
Embryonic stem cell | DNA methylation | Differentiation | Endothelial cells | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Neovascularization, Physiologic - drug effects | Embryonic Stem Cells - cytology | Cadherins - metabolism | Gene Expression - drug effects | Gene Expression - genetics | Bone Morphogenetic Protein 4 - genetics | von Willebrand Factor - genetics | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Promoter Regions, Genetic - genetics | Antigens, CD - metabolism | Octamer Transcription Factor-3 - genetics | Receptor, TIE-2 - metabolism | Cadherins - genetics | Cell Differentiation - physiology | von Willebrand Factor - metabolism | Cell Line | Basic Helix-Loop-Helix Transcription Factors - genetics | DNA (Cytosine-5-)-Methyltransferase 1 | Endothelial Cells - metabolism | Cells, Cultured | Azacitidine - analogs & derivatives | Up-Regulation - genetics | DNA Methylation - genetics | Down-Regulation - genetics | Receptor, TIE-2 - genetics | Angiopoietin-1 - genetics | Azacitidine - pharmacology | Animals | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Endothelial Cells - cytology | Octamer Transcription Factor-3 - metabolism | CpG Islands - genetics | Mice | Sulfites | Endothelial growth factors | Immunocytochemistry | Leukemia | Embryonic stem cells | Gene expression | Endothelium | Stem cell research | Promoters (Genetics) | Methyltransferases | DNA | Genetic research | Bone morphogenetic proteins | Methylation | Genetics | Cellular biology | Rodents | Deoxyribonucleic acid--DNA | Stem cells | Index Medicus | endothelial cells | embryonic stem cell
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3. Full Text Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3
by Zeng, Heng and He, Xiaochen and Hou, Xuwei and Li, Lanfang and Chen, Jian-Xiong
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 02/2014, Volume 306, Issue 4, pp. H585 - H597
VEGF/VEGFR2 | Diabetic cardiomyopathy | Angiogenesis | Sirtuin 3 | Ang-1/Tie-2 | Apelin | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Diabetic Cardiomyopathies - metabolism | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Male | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiopoietin-2 - metabolism | Diabetic Cardiomyopathies - physiopathology | Receptors, Vascular Endothelial Growth Factor - metabolism | Myocardium - metabolism | Neovascularization, Pathologic - physiopathology | Receptor, TIE-2 - metabolism | Diabetic Cardiomyopathies - therapy | Receptors, Vascular Endothelial Growth Factor - genetics | Neovascularization, Pathologic - therapy | Heart - physiopathology | Sirtuin 3 - genetics | Endothelium, Vascular - physiopathology | Intercellular Signaling Peptides and Proteins - genetics | Up-Regulation - genetics | Adipokines | Receptor, TIE-2 - genetics | Diabetic Cardiomyopathies - genetics | Angiopoietin-1 - genetics | Animals | Endothelium, Vascular - metabolism | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Apoptosis - physiology | Prevention | Cardiomyopathy | Physiological aspects | Genetic research | Genetic aspects | Research | Diabetes | Gene therapy | Heart diseases | Heart failure | Rodents | Glucose | Apoptosis | Index Medicus | VEGFR2 | apelin | Tie-2 | sirtuin 3 | VEGF | angiogenesis | Ang-1 | diabetic cardiomyopathy | Integrative Cardiovascular Physiology and Pathophysiology
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4. Full Text BAMBI Elimination Enhances Alternative TGF-beta Signaling and Glomerular Dysfunction in Diabetic Mice
by Fan, Ying and Li, Xuezhu and Xiao, Wenzhen and Fu, Jia and Harris, Ray C and Lindenmeyer, Maja and Cohen, Clemens D and Guillot, Nicolas and Baron, Margaret H and Wang, Niansong and Lee, Kyung and He, John C and Schlondorff, Detlef and Chuang, Peter Y
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2015, Volume 64, Issue 6, pp. 2220 - 2233
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Membrane Proteins - genetics | Humans | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Kidney Glomerulus - pathology | Angiopoietin-1 - metabolism | Blotting, Western | Vascular Endothelial Growth Factor Receptor-2 - genetics | Angiopoietin-1 - genetics | Animals | Smad5 Protein - metabolism | Smad1 Protein - genetics | Kidney Glomerulus - metabolism | Smad1 Protein - metabolism | Signal Transduction - physiology | Membrane Proteins - metabolism | Mice | Smad5 Protein - genetics | In Vitro Techniques | Transforming Growth Factor beta - metabolism | Glomerulonephritis | Type 2 diabetes | Genetically modified mice | Care and treatment | Usage | Activins | Research | Transforming growth factors | Index Medicus | Abridged Index Medicus | Life Sciences | Complications
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5. Full Text Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis
by Pesesse, L and Sanchez, C and Delcour, J.-P and Bellahcène, A and Baudouin, C and Msika, P and Henrotin, Y
Osteoarthritis and cartilage, ISSN 1063-4584, 2013, Volume 21, Issue 12, pp. 1913 - 1923
Rheumatology | Angiogenesis | Bone sialoprotein | Chondrocyte hypertrophy | Osteoarthritis | Life Sciences & Biomedicine | Orthopedics | Science & Technology | Osteopontin - genetics | Up-Regulation | Thrombospondins - genetics | Humans | Osteopontin - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Osteoarthritis - physiopathology | Intercellular Signaling Peptides and Proteins - metabolism | Cartilage, Articular - metabolism | Thrombospondin 1 - genetics | Fibroblast Growth Factor 2 - metabolism | Neovascularization, Pathologic - physiopathology | Membrane Proteins - metabolism | Chondrocytes - metabolism | Endothelial Cells - physiology | Chondrocytes - pathology | Nerve Growth Factor - metabolism | Cartilage, Articular - cytology | Matrix Metalloproteinase 2 - metabolism | Membrane Proteins - genetics | Cells, Cultured | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Osteoarthritis - metabolism | Nerve Growth Factor - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Osteoarthritis - genetics | Angiopoietin-1 - genetics | Matrix Metalloproteinase 2 - genetics | Fibroblast Growth Factor 2 - genetics | Integrin-Binding Sialoprotein - genetics | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Thrombospondin 1 - metabolism | Integrin-Binding Sialoprotein - metabolism | Thrombospondins - metabolism | Cell Movement | Hypertrophy | Index Medicus
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6. Full Text Hypoxia-inducible hydrogels
by Park, Kyung Min and Gerecht, Sharon
Nature communications, ISSN 2041-1723, 06/2014, Volume 5, Issue 1, pp. 4075 - 4075
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Matrix Metalloproteinases - genetics | Humans | Gene Expression Profiling | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Oxygen - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Computer Simulation | Hydrogels - metabolism | Wound Healing - genetics | Gelatin - chemistry | Laccase | Basic Helix-Loop-Helix Transcription Factors - genetics | Endothelial Cells - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Neovascularization, Physiologic - genetics | Oxygen Consumption | Cellular Microenvironment | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Angiopoietin-1 - genetics | Neovascularization, Physiologic - physiology | Biocompatible Materials | Matrix Metalloproteinases - metabolism | Coumaric Acids | Index Medicus
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7. Full Text Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms
by Horiguchi, Hiroto and Kobune, Masayoshi and Kikuchi, Shohei and Yoshida, Masahiro and Murata, Masaki and Murase, Kazuyuki and Iyama, Satoshi and Takada, Kohichi and Sato, Tsutomu and Ono, Kaoru and Hashimoto, Akari and Tatekoshi, Ayumi and Kamihara, Yusuke and Kawano, Yutaka and Miyanishi, Koji and Sawada, Norimasa and Kato, Junji
Haematologica (Roma), ISSN 0390-6078, 03/2016, Volume 101, Issue 4, pp. 437 - 447
Life Sciences & Biomedicine | Hematology | Science & Technology | Lymphoma - physiopathology | Extracellular Vesicles - chemistry | Jagged-1 Protein - metabolism | Coculture Techniques | Humans | Leukemia, Myeloid, Acute - metabolism | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Gene Expression Profiling | Stem Cell Factor - genetics | Angiopoietin-1 - metabolism | Extracellular Vesicles - metabolism | Lymphoma - metabolism | Molecular Mimicry | Transfection | Oligoribonucleotides - metabolism | Myelodysplastic Syndromes - metabolism | Myelodysplastic Syndromes - physiopathology | Stem Cell Factor - metabolism | Signal Transduction | Extracellular Vesicles - pathology | Bone Marrow Cells - pathology | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Lymphoma - genetics | Mesenchymal Stromal Cells - metabolism | Hematopoiesis - genetics | Jagged-1 Protein - genetics | Heterogeneous-Nuclear Ribonucleoproteins - genetics | Angiopoietin-1 - genetics | MicroRNAs - genetics | Myelodysplastic Syndromes - genetics | Mesenchymal Stromal Cells - pathology | Primary Cell Culture | Neoplasm Staging | Bone Marrow Cells - metabolism | Leukemia, Myeloid, Acute - physiopathology | Leukemia, Myeloid, Acute - genetics | Oligoribonucleotides - genetics | Index Medicus
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8. Full Text Linking transgene expression of engineered mesenchymal stem cells and angiopoietin-1-induced differentiation to target cancer angiogenesis
by Conrad, Claudius and Hüsemann, Yves and Niess, Hanno and Von Luettichau, Irene and Huss, Ralf and Bauer, Christian and Jauch, Karl-Walter and Klein, Christoph A and Bruns, Christiane and Nelson, Peter J
Annals of surgery, ISSN 0003-4932, 03/2011, Volume 253, Issue 3, pp. 566 - 571
Life Sciences & Biomedicine | Surgery | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Adenocarcinoma - pathology | Receptor, TIE-2 | Gene Expression - genetics | Mammary Neoplasms, Experimental - genetics | Neovascularization, Pathologic - pathology | Cell Transformation, Neoplastic - genetics | Mammary Neoplasms, Experimental - pathology | Female | Adenocarcinoma - genetics | Angiopoietin-1 - pharmacology | Gene Targeting | Genes, Transgenic, Suicide - genetics | Thymidine Kinase - genetics | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Simplexvirus - genetics | Transgenes - genetics | Mesenchymal Stromal Cells - metabolism | Genes, Reporter - genetics | Mice, Transgenic | Pancreatic Neoplasms - genetics | Animals | Genetic Engineering | Receptor Protein-Tyrosine Kinases - genetics | Neovascularization, Pathologic - genetics | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Mesenchymal Stem Cell Transplantation | Genetic Therapy - methods | Index Medicus | Abridged Index Medicus
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9. Effects of angiopoietin-1 on inflammatory injury in endothelial progenitor cells and blood vessels
by Wang, Yi-Qing and Song, Jing-Jin and Han, Xiao and Liu, Yi-Ye and Wang, Xi-Huang and Li, Zhi-ming and Tzeng, Chi-Meng
Current gene therapy, ISSN 1566-5232, 2014, Volume 14, Issue 2, pp. 128 - 135
Angiopoietin-1 | Inflammation | Carotid balloon catheter injury | Endothelial progenitor cells | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Blood Vessels - metabolism | Tumor Necrosis Factor-alpha - genetics | Cell Survival - genetics | Male | Neovascularization, Pathologic - virology | Angiopoietin-1 - metabolism | Inflammation - metabolism | Endothelial Progenitor Cells - virology | Proliferating Cell Nuclear Antigen - genetics | Blood Vessels - virology | Lentivirus - genetics | Vascular Cell Adhesion Molecule-1 - genetics | Endothelial Progenitor Cells - metabolism | Cells, Cultured | Inflammation - virology | Rats | Rats, Sprague-Dawley | Genetic Vectors - genetics | Angiopoietin-1 - genetics | Intercellular Adhesion Molecule-1 - metabolism | Animals | Intercellular Adhesion Molecule-1 - genetics | Inflammation - genetics | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Transcription, Genetic - genetics | Proliferating Cell Nuclear Antigen - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Genetic Therapy - methods
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10. Full Text Angiopoietin-1/Tie2 signal augments basal notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of β-catenin
by Zhang, Jianghui and Fukuhara, Shigetomo and Sako, Keisuke and Takenouchi, Takato and Kitani, Hiroshi and Kume, Tsutomu and Koh, Gou Young and Mochizuki, Naoki
The Journal of biological chemistry, ISSN 0021-9258, 03/2011, Volume 286, Issue 10, pp. 8055 - 8066
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Phosphorylation - physiology | Receptors, Notch - metabolism | Extracellular Matrix - metabolism | Glycogen Synthase Kinase 3 beta | Receptors, Notch - genetics | Phosphatidylinositol 3-Kinases - metabolism | Angiopoietin-1 - metabolism | Proto-Oncogene Proteins c-akt - genetics | beta Catenin - biosynthesis | Extracellular Matrix - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Umbilical Veins - cytology | Calcium-Binding Proteins | Endothelial Cells - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Gene Expression Regulation - physiology | Glycogen Synthase Kinase 3 - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | beta Catenin - genetics | Phosphatidylinositol 3-Kinases - genetics | Angiopoietin-1 - genetics | Neovascularization, Physiologic - physiology | Adaptor Proteins, Signal Transducing | Glycogen Synthase Kinase 3 - genetics | Receptor Protein-Tyrosine Kinases - genetics | Endothelial Cells - cytology | Signal Transduction - physiology | Umbilical Veins - metabolism | Index Medicus | Δ-Like 4 | Signal Transduction | Extracellular Matrix Proteins | Tie2 | Vascular Quiescence | Angiopoietin-1 | β-Catenin | Glycogen Synthase Kinase 3 | Notch Pathway | AKT PKB | Endothelium
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