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humans (175) 175
animals (125) 125
angiopoietin-2 - biosynthesis (114) 114
angiogenesis (111) 111
angiopoietin-2 (102) 102
mice (95) 95
index medicus (92) 92
female (81) 81
male (72) 72
angiopoietin-2 - genetics (64) 64
endothelial growth-factor (54) 54
oncology (54) 54
angiopoietin-1 (53) 53
expression (52) 52
angiopoietin-1 - biosynthesis (51) 51
immunohistochemistry (50) 50
in-vivo (50) 50
tie2 receptor (42) 42
vascular endothelial growth factor a - biosynthesis (42) 42
angiopoietin (41) 41
reverse transcriptase polymerase chain reaction (41) 41
neovascularization, pathologic - metabolism (40) 40
tumor angiogenesis (40) 40
vegf (40) 40
middle aged (39) 39
rna, messenger - biosynthesis (39) 39
vascular endothelial growth factor (36) 36
cells, cultured (34) 34
aged (33) 33
angiopoietin-1 - genetics (33) 33
endothelial-cells (32) 32
cell line, tumor (31) 31
neovascularization, pathologic - genetics (31) 31
membrane glycoproteins - biosynthesis (30) 30
protein biosynthesis (30) 30
receptor, tie-2 (30) 30
gene expression (29) 29
adult (28) 28
rats (28) 28
cancer (27) 27
receptor, tie-2 - biosynthesis (27) 27
angiopoietin-2 - metabolism (26) 26
hematology (26) 26
rna, messenger - genetics (26) 26
hypoxia (25) 25
up-regulation (25) 25
angiopoietins (24) 24
biochemistry & molecular biology (24) 24
blotting, western (24) 24
growth-factor (24) 24
proteins - genetics (24) 24
receptor tyrosine kinase (24) 24
receptor, tie-2 - genetics (24) 24
time factors (24) 24
vascular endothelial growth factor a (24) 24
cell biology (23) 23
membrane glycoproteins - genetics (23) 23
neovascularization, pathologic (23) 23
vascular endothelial growth factor a - genetics (23) 23
vascular endothelial growth factors (23) 23
cells (21) 21
gene expression regulation, neoplastic (21) 21
growth (21) 21
tie2 (21) 21
mice, nude (20) 20
cardiovascular system (19) 19
endothelium (19) 19
endothelium, vascular - metabolism (19) 19
receptor (19) 19
vascular endothelial growth factor a - metabolism (19) 19
analysis (18) 18
inflammation (18) 18
proteins (18) 18
receptor, tie-2 - metabolism (18) 18
survival (18) 18
article (17) 17
neovascularization (17) 17
research (17) 17
tumors (17) 17
endothelial cells (16) 16
endothelial growth factors - biosynthesis (16) 16
mice, inbred c57bl (16) 16
peripheral vascular disease (16) 16
rna, messenger - metabolism (16) 16
signal transduction (16) 16
endothelial cells - metabolism (15) 15
in situ hybridization (15) 15
neovascularization, pathologic - pathology (15) 15
pathology (15) 15
abridged index medicus (14) 14
angiopoietin-1 - metabolism (14) 14
blood-vessel formation (14) 14
lymphokines - biosynthesis (14) 14
metastasis (14) 14
neoplasm transplantation (14) 14
transfection (14) 14
angiopoietin-2 - physiology (13) 13
apoptosis (13) 13
carcinoma (13) 13
endothelium, vascular - cytology (13) 13
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Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 7, pp. 4183 - 4190
Journal Article
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2008, Volume 109, Issue 3, pp. 418 - 425
Journal Article
Cancer Research, ISSN 0008-5472, 01/2006, Volume 66, Issue 1, pp. 184 - 191
Bone marrow angiogenesis plays an important role in the pathogenesis and progression in multiple myeloma. Recent studies have shown that proteasome inhibitor... 
EMBRYO CHORIOALLANTOIC MEMBRANE | MIGRATION | MURINE MODEL | METASTASIS | ONCOLOGY | PROTEASOME INHIBITOR PS-341 | BONE-MARROW | GROWTH-FACTOR | TUMOR ANGIOGENESIS | SIGNALING CASCADES | CANCER | Neovascularization, Physiologic - drug effects | Vascular Endothelial Growth Factor A - biosynthesis | Interleukin-6 - antagonists & inhibitors | Angiopoietin-2 - genetics | Humans | Insulin-Like Growth Factor I - genetics | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Neovascularization, Pathologic - pathology | Vascular Endothelial Growth Factor A - secretion | Dose-Response Relationship, Drug | Multiple Myeloma - drug therapy | Antineoplastic Agents - pharmacology | Angiopoietin-1 - biosynthesis | Chorioallantoic Membrane - blood supply | Insulin-Like Growth Factor I - biosynthesis | Bortezomib | Interleukin-6 - genetics | Cell Growth Processes - drug effects | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Angiopoietin-2 - biosynthesis | Down-Regulation - drug effects | Multiple Myeloma - blood supply | Reverse Transcriptase Polymerase Chain Reaction | Chick Embryo | Interleukin-6 - secretion | Angiopoietin-1 - genetics | Animals | Endothelial Cells - secretion | Neovascularization, Pathologic - drug therapy | Interleukin-6 - biosynthesis | Neovascularization, Pathologic - genetics | Pyrazines - pharmacology | Multiple Myeloma - genetics | Boronic Acids - pharmacology | Endothelial Cells - drug effects
Journal Article
Cancer Research, ISSN 0008-5472, 06/2003, Volume 63, Issue 12, pp. 3403 - 3412
Vascular remodeling in host tissues surrounding growing tumors is implicated in the successful development of tumor neovasculature. Cooperation between... 
FACTOR VEGF | LASER CAPTURE MICRODISSECTION | ACTIVATION | ONCOLOGY | TIE2 | IN-VIVO | CELL SURVIVAL | BLOOD-VESSEL FORMATION | POSSIBLE MECHANISM | EXPRESSION | CARCINOMA | Carcinoma - secretion | Nucleic Acid Synthesis Inhibitors - pharmacology | Receptor, TIE-2 | Vascular Endothelial Growth Factors | Humans | Membrane Glycoproteins - biosynthesis | Ovarian Neoplasms - pathology | Angiopoietin-1 | Angiopoietin-2 | Endothelium, Vascular - drug effects | Neoplasm Proteins - pharmacology | Endothelial Growth Factors - pharmacology | RNA, Messenger - biosynthesis | Pericytes - pathology | Neovascularization, Pathologic - physiopathology | Ovarian Neoplasms - blood supply | Neoplasm Proteins - genetics | Endothelial Growth Factors - physiology | Lymphokines - physiology | Carcinoma - physiopathology | Angiogenesis Inducing Agents - genetics | RNA, Neoplasm - biosynthesis | Endothelium, Vascular - metabolism | Intercellular Signaling Peptides and Proteins - pharmacology | Models, Biological | Carcinoma - blood supply | Mice | Vascular Endothelial Growth Factor A | Neoplasm Proteins - physiology | Receptor Protein-Tyrosine Kinases - biosynthesis | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - physiopathology | Recombinant Fusion Proteins - physiology | Cell Line, Transformed - drug effects | Intercellular Signaling Peptides and Proteins - physiology | Stromal Cells - drug effects | Female | Lymphokines - pharmacology | Carcinoma - pathology | Genes, Reporter | Recombinant Fusion Proteins - biosynthesis | Angiogenesis Inducing Agents - biosynthesis | Paracrine Communication | Neoplasm Proteins - biosynthesis | Mice, Inbred C57BL | Stromal Cells - metabolism | Membrane Glycoproteins - genetics | Ovarian Neoplasms - secretion | Animals | Receptor Protein-Tyrosine Kinases - genetics | Cell Line, Transformed - metabolism | Dactinomycin - pharmacology
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2005, Volume 24, Issue 11, pp. 1976 - 1987
The ecotropic viral integration site‐1 ( Evi1 ) is an oncogenic transcription factor in murine and human myeloid leukemia. We herein show that Evi1 is... 
Evi1 | angiopoiesis | hematopoiesis | GATA‐2 | Angiopoiesis | Hematopoiesis | GATA-2 | MYELOID-TRANSFORMING GENE | YOLK-SAC | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE EMBRYOS | PARAAORTIC SPLANCHNOPLEURA | CELL BIOLOGY | DEFINITIVE HEMATOPOIESIS | ZINC-FINGER PROTEIN | MICE | LEUKEMIA | DIFFERENTIATION | BINDING | Angiopoietin-2 - genetics | Cells, Cultured - cytology | Humans | Blood Vessels - embryology | RNA, Messenger - biosynthesis | Yolk Sac - blood supply | Proto-Oncogenes - genetics | Gene Expression Regulation, Developmental | Bone Marrow - metabolism | Cell Division | Transcription, Genetic | Hematopoietic System - embryology | Proto-Oncogenes - physiology | Angiopoietin-1 - biosynthesis | Promoter Regions, Genetic | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Neovascularization, Physiologic - genetics | Receptor, TIE-2 - biosynthesis | Angiopoietin-2 - biosynthesis | Hematopoiesis - genetics | Transcription Factors - biosynthesis | Hematopoietic Stem Cells - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Knockout | Receptor, TIE-2 - genetics | Angiopoietin-1 - genetics | Neovascularization, Physiologic - physiology | Animals | Hematopoietic Stem Cells - cytology | Cells, Cultured - metabolism | GATA2 Transcription Factor | Mice | DNA-Binding Proteins - biosynthesis | MDS1 and EVI1 Complex Locus Protein
Journal Article
Genes and Development, ISSN 0890-9369, 10/2002, Volume 16, Issue 19, pp. 2530 - 2543
Journal Article
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 2002, Volume 16, Issue 14, pp. 1928 - 1930
We previously have found that advanced glycation end products (AGE), senescent macroproteins formed at an accelerated rate in diabetes, arise in vivo not only... 
CELLS | ADVANCED GLYCOSYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANGIOPOIETIN-1 | receptor for AGE | DIABETIC NEPHROPATHY | VASCULAR PERICYTES | CELL BIOLOGY | vascular endothelial growth factor | reactive oxygen species | IN-VIVO | BIOLOGY | NF-KAPPA-B | PROSTACYCLIN-PRODUCING ABILITY | ENDOTHELIAL GROWTH-FACTOR | TIE2 RECEPTOR | Endothelium, Vascular - cytology | Up-Regulation | Vascular Endothelial Growth Factor A | Vascular Endothelial Growth Factors | Humans | Transcriptional Activation | Glycation End Products, Advanced - antagonists & inhibitors | Angiopoietin-2 | Endothelium, Vascular - drug effects | Intercellular Signaling Peptides and Proteins - biosynthesis | NF-kappa B - metabolism | Transcription Factor AP-1 - metabolism | RNA, Messenger - biosynthesis | Lymphokines - genetics | DNA - biosynthesis | Lymphokines - biosynthesis | Receptor for Advanced Glycation End Products | Angiogenesis Inducing Agents - biosynthesis | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Endothelial Growth Factors - biosynthesis | Endothelium, Vascular - growth & development | Angiogenesis Inducing Agents - genetics | Microcirculation - cytology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Glycation End Products, Advanced - pharmacology | Models, Biological | Endothelial Growth Factors - genetics | Glycation End Products, Advanced - metabolism | Pyridines - pharmacology | Neovascularization, Physiologic | Receptors, Immunologic - metabolism
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2014, Volume 110, Issue 2, pp. 441 - 449
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 27, pp. 11187 - 11192
Journal Article
Cancer Research, ISSN 0008-5472, 04/2006, Volume 66, Issue 8, pp. 4125 - 4132
The mechanism of thrombin-induced angiogenesis is poorly understood. Using a gene chip array to investigate the promalignant phenotype of thrombin-stimulated... 
ADHESION | METASTASIS | INCREASED EXPRESSION | MECHANISM | ONCOLOGY | PLATELETS | SQUAMOUS-CELL CARCINOMA | RECEPTOR | TUMOR-CELLS | CXC CHEMOKINES | VEIN ENDOTHELIAL-CELLS | Neoplasms - metabolism | Neovascularization, Physiologic - drug effects | RNA, Small Interfering - genetics | Vascular Endothelial Growth Factor A - biosynthesis | Humans | Thrombin - antagonists & inhibitors | Molecular Sequence Data | Cell Growth Processes - physiology | Intercellular Signaling Peptides and Proteins - biosynthesis | Matrix Metalloproteinase 1 - biosynthesis | RNA, Messenger - biosynthesis | Thrombin - pharmacology | Chemokines, CXC - pharmacology | Intercellular Signaling Peptides and Proteins - secretion | Chemokines, CXC - biosynthesis | Amino Acid Sequence | Cell Growth Processes - drug effects | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Angiopoietin-2 - biosynthesis | Neoplasms - blood supply | Chemokines, CXC - genetics | Chick Embryo | Chemokines, CXC - secretion | Up-Regulation - drug effects | Neovascularization, Physiologic - physiology | Animals | Endothelial Cells - cytology | Endothelial Cells - secretion | Intercellular Signaling Peptides and Proteins - pharmacology | Cell Line, Tumor | Chemokine CXCL1 | Mice | Mice, Inbred BALB C | Neoplasms - pathology | Endothelial Cells - drug effects
Journal Article
Annals of Hematology, ISSN 0939-5555, 1/2013, Volume 92, Issue 1, pp. 101 - 109
Multiple myeloma (MM) is classically illustrated by a desynchronized cytokine system with rise in inflammatory cytokines. There are recent reports which... 
Angiogenesis | Cyclooxygenase | Medicine & Public Health | Hematology | Multiple myeloma | Angiopoietins | Oncology | ANGIOPOIETIN-2 EXPRESSION | TUMOR ANGIOGENESIS | BONE-MARROW ANGIOGENESIS | RECEPTOR C-MET | IN-VIVO | HEMATOLOGICAL MALIGNANCIES | UNDETERMINED SIGNIFICANCE | MONOCLONAL GAMMOPATHY | HEMATOLOGY | ENDOTHELIAL GROWTH-FACTOR | CLINICAL-SIGNIFICANCE | Hematopoietic Cell Growth Factors - blood | Angiopoietin-2 - genetics | Humans | Middle Aged | Male | Gene Expression Profiling | RNA, Neoplasm - blood | Cyclooxygenase 2 - biosynthesis | Young Adult | Hematopoietic Cell Growth Factors - genetics | RNA, Messenger - biosynthesis | Multiple Myeloma - drug therapy | Cyclooxygenase 2 - blood | Cyclooxygenase 2 - genetics | Angiogenesis Inhibitors - therapeutic use | Angiopoietin-1 - blood | Adult | Female | Neoplasm Proteins - genetics | Real-Time Polymerase Chain Reaction | Angiopoietin-1 - biosynthesis | Angiopoietin-2 - blood | Multiple Myeloma - blood | Enzyme-Linked Immunosorbent Assay | Neoplasm Proteins - biosynthesis | Hematopoietic Cell Growth Factors - biosynthesis | Angiopoietin-2 - biosynthesis | Disease Progression | India | Angiopoietin-1 - genetics | RNA, Messenger - blood | RNA, Neoplasm - biosynthesis | Neoplasm Proteins - blood | Neovascularization, Pathologic - genetics | Aged | Multiple Myeloma - genetics | COX-2 inhibitors | Enzymes | RNA | Endothelial growth factors | Nuclear radiation | Neovascularization | Enzyme-linked immunosorbent assay | Tumors
Journal Article
Journal Article