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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 2013, Volume 33, Issue 7, pp. 1529 - 1537
OBJECTIVE: Macrophage foam cells play a crucial role in several pathologies including multiple sclerosis, glomerulosclerosis, and atherosclerosis.... 
Lipoproteins | Inflammation | Lipoprotein lipase | Macrophages | Atherosclerosis | atherosclerosis | HYPERLIPIDEMIA | LOW-DENSITY-LIPOPROTEIN | macrophages | HYPERLIPOPROTEINEMIA | GENE | inflammation | FOAM CELL-FORMATION | lipoprotein lipase | PERIPHERAL VASCULAR DISEASE | LIPASE | ANGPTL4 | HEMATOLOGY | EXPRESSION | lipoproteins | MOUSE PERITONEAL-MACROPHAGES | TRANSGENIC MICE | Up-Regulation | Carotid Stenosis - prevention & control | Atherosclerosis - genetics | Cholesterol - blood | Humans | Middle Aged | Male | Aorta - metabolism | Aortic Diseases - metabolism | Angiopoietin-like 4 Protein | Time Factors | Diet, High-Fat | Aortic Diseases - prevention & control | Toll-Like Receptor 4 - agonists | Female | Lipoproteins, LDL - metabolism | Foam Cells - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Cell Line | Angiopoietins - metabolism | Atherosclerosis - pathology | Mice, Inbred C57BL | Mice, Transgenic | Toll-Like Receptor 3 - agonists | Carotid Stenosis - pathology | Toll-Like Receptor 3 - metabolism | Angiopoietins - blood | Chemotaxis | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Macrophage Activation | Aorta - pathology | Magnetic Resonance Imaging | Aortic Diseases - genetics | Apolipoprotein E3 - genetics | Macrophages - metabolism | Animals | Triglycerides - blood | Ligands | Macrophages - drug effects | Carotid Arteries - pathology | Mice | Angiopoietins - genetics | Carotid Stenosis - blood | Atherosclerosis - prevention & control | mouse peritoneal-macrophages | foam cell-formation | hyperlipidemia | expression | transgenic mice | gene | low-density-lipoprotein | lipase | angptl4 | hyperlipoproteinemia
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2006, Volume 103, Issue 46, pp. 17450 - 17455
Lipoprotein lipase (LPL) has a central role in lipoprotein metabolism to maintain normal lipoprotein levels in blood and, through tissue specific regulation of... 
Adipose tissues | Enzymes | Lipoproteins | Messenger RNA | Dimers | Surface plasmon resonance | Heparin | Sensors | Monomers | Food | Protein folding | Chaperone | Heparin affinity | NUTRITIONAL STATE | heparin affinity | MULTIDISCIPLINARY SCIENCES | chaperone I | DOWN-REGULATION | GUINEA-PIG | HEART | OVEREXPRESSION | INHIBITION | METABOLISM | surface plasmon resonance | GENETICS | ANGPTL3 | protein folding | Surface Plasmon Resonance | Heparin - metabolism | Blood Proteins - metabolism | Angiopoietin-like 4 Protein | Blood Proteins - genetics | Blood Proteins - isolation & purification | Protein Structure, Quaternary | Lipoprotein Lipase - chemistry | Dimerization | Lipoprotein Lipase - metabolism | Angiopoietins - metabolism | Gene Expression | RNA, Messenger - genetics | Models, Molecular | Rats | Blood Proteins - chemistry | Protein Folding | Animals | Chromatography, Affinity | Angiopoietins - chemistry | Heparin - analogs & derivatives | Protein Binding | Adipose Tissue - enzymology | Mice | Enzyme Activation | Angiopoietins - genetics | Lipoprotein lipase | Research | Molecular chaperones | Biological Sciences | chaperone | Models; Molecular | Lipoprotein Lipase/chemistry/metabolism | Heparin/analogs & derivatives/metabolism | Chromatography; Affinity | Angiopoietins/chemistry/genetics/metabolism | Blood Proteins/chemistry/genetics/isolation & purification/metabolism | Adipose Tissue/enzymology | RNA; Messenger/genetics | Protein Structure; Quaternary
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. 1 - 7
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 02/2020, Volume 1865, Issue 2, p. 158553
Pancreatic lipase (PNLIP) is a digestive enzyme that is a potential drug target for the treatment of obesity. A better understanding of its regulation... 
Complex substrate emulsion | Lipase inhibitors | Human pancreatic lipase | Isothermal titration calorimetry | Emulsion aggregation | Angiopoietin-like protein 4
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2014, Volume 192, Issue 11, pp. 5354 - 5362
The angiopoietin-like protein 4 (angptl4, also known as peroxisome proliferator-activated receptor [PPAR]γ-induced angiopoietin-related protein) is a... 
Transcription, Genetic - drug effects | Leukocytes, Mononuclear - secretion | Humans | Male | MAP Kinase Signaling System - immunology | Angiopoietins - immunology | Angiopoietin-like Proteins | Leukocytes, Mononuclear - immunology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Female | Phosphorylation - immunology | Phosphorylation - drug effects | Transcription Factors - immunology | alpha 1-Antitrypsin - immunology | Serine Proteinase Inhibitors - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - immunology | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Angiopoietins - secretion | Gene Expression Regulation - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Serine Proteinase Inhibitors - immunology | Emphysema - drug therapy | Endothelial Cells - immunology | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Emphysema - immunology | Leukocytes, Mononuclear - pathology | Emphysema - pathology | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Endothelial Cells - secretion | Anilides - pharmacology | Transcription, Genetic - immunology | alpha 1-Antitrypsin - pharmacology | alpha 1-Antitrypsin - metabolism | Endothelial Cells - pathology | Mitogen-Activated Protein Kinase 1 - metabolism
Journal Article
Journal Article