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angiopoietin-2 - blood (19) 19
angiopoietin-like proteins (19) 19
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diabetes (17) 17
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angiopoietin-2 - metabolism (16) 16
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endocrinology & metabolism (15) 15
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angiopoietins - antagonists & inhibitors (14) 14
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 38, pp. 25593 - 25601
Glucocorticoids are important regulators of lipid homeostasis, and chronically elevated glucocorticoid levels induce hypertriglyceridemia, hepatic steatosis,... 
OBESITY | PLASMA | GENE | CHROMATIN | ANGIOGENESIS | DIET | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYPERLIPIDEMIA | MICE | TRANSCRIPTIONAL REGULATION | PROTEIN-4 | Transcription, Genetic - drug effects | Hypertriglyceridemia - genetics | Humans | Dexamethasone - adverse effects | Receptors, Glucocorticoid - metabolism | Hepatocytes - metabolism | Fatty Liver - chemically induced | Adipose Tissue - metabolism | Angiopoietin-like 4 Protein | Dexamethasone - pharmacology | Glucocorticoids - genetics | Glucocorticoids - metabolism | Response Elements - genetics | Lipoprotein Lipase - metabolism | Glucocorticoids - adverse effects | Fatty Liver - genetics | Angiopoietins - metabolism | Fatty Liver - metabolism | Lipoprotein Lipase - genetics | Liver - metabolism | Rats | Hypertriglyceridemia - metabolism | Mice, Knockout | Triglycerides - metabolism | Adipose Tissue, White | Hypertriglyceridemia - chemically induced | Animals | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Dexamethasone - metabolism | Glucocorticoids - pharmacology | Mice | Transcription, Genetic - genetics | Triglycerides - genetics | Angiopoietins - genetics | Index Medicus | Lipids and Lipoproteins | Metabolism, Regulation, and Signaling | Transcription | Dermatologi och venereologi | Dermatology and Venereal Diseases | Dexamethasone/adverse effects/metabolism/pharmacology | Hypertriglyceridemia/chemically induced/genetics/metabolism | Receptors | Adipose Tissue/metabolism | Liver/metabolism | Tumor | Adipose Tissue | Cell Line | Fatty Liver/chemically induced/genetics/metabolism | Triglycerides/genetics/ metabolism | Response Elements/genetics | Angiopoietins/genetics/ metabolism | Knockout | Lipoprotein Lipase/genetics/metabolism | White | Hepatocytes/metabolism | Genetic/drug effects/genetics | Glucocorticoids/adverse effects/genetics/ metabolism/pharmacology | Glucocorticoid/genetics/ metabolism
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2014, Volume 135, Issue 1, pp. 25 - 33
Abstract Objective To examine the tolerability and antitumor activity of trebananib plus pegylated liposomal doxorubicin (PLD) or topotecan in recurrent... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Tie2 receptor | Angiogenesis | Dose-limiting toxicities | Combination treatments | Targeted therapy | Angiopoietins | SOLID TUMORS | ANGIOPOIETIN-2 | SUPPRESSION | CHEMOTHERAPY | OBSTETRICS & GYNECOLOGY | INHIBITION | ONCOLOGY | DOUBLE-BLIND | CARCINOMA | AMG 386 | III TRIAL | Recombinant Fusion Proteins - adverse effects | Humans | Middle Aged | Antibiotics, Antineoplastic - adverse effects | Neoplasm Recurrence, Local - drug therapy | Polyethylene Glycols - adverse effects | Drug Resistance, Neoplasm | Platinum Compounds - therapeutic use | Angiogenesis Inhibitors - administration & dosage | Doxorubicin - analogs & derivatives | Aged, 80 and over | Adult | Female | Drug Therapy, Combination | Angiogenesis Inhibitors - adverse effects | Ovarian Neoplasms - drug therapy | Recombinant Fusion Proteins - administration & dosage | Doxorubicin - administration & dosage | Platinum Compounds - adverse effects | Topoisomerase I Inhibitors - administration & dosage | Topotecan - adverse effects | Polyethylene Glycols - administration & dosage | Antibiotics, Antineoplastic - administration & dosage | Topoisomerase I Inhibitors - adverse effects | Topotecan - administration & dosage | Aged | Doxorubicin - adverse effects | Women | Anthracyclines | Ovarian cancer
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 3, pp. 211 - 221
Loss-of-function variants in ANGPTL3 were associated with lower plasma levels of lipids and lower rates of coronary disease. A monoclonal antibody against... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | IMMUNOGLOBULIN GENES | ATHEROSCLEROSIS | RISK | CORONARY-ARTERY-DISEASE | FAMILIAL COMBINED HYPOLIPIDEMIA | LIPOPROTEIN-LIPASE GENE | TRANSGENIC MICE | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Angiopoietins - antagonists & inhibitors | Dose-Response Relationship, Drug | Dyslipidemias - blood | Angiopoietin-like Proteins | Lipids - blood | Female | Disease Models, Animal | Dyslipidemias - drug therapy | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Coronary Artery Disease - metabolism | Mice, Inbred Strains | Atherosclerosis - metabolism | Animals | Antibodies, Monoclonal - administration & dosage | Coronary Artery Disease - genetics | Lipid Metabolism - drug effects | Aged | Mice | Mutation | Angiopoietins - genetics | Cholesterol, LDL | Research | Antibiosis | Atherosclerosis | Lipoproteins (low density) | Medical research | Angiopoietin | Genomics | Genes | Coronary artery | Triglycerides | Biochemistry | Gene expression | Cholesterol | Serum levels | Proteins | Antagonism | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Heart diseases | Drug dosages | Pharmaceuticals
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2015, Volume 33, Issue 30, pp. 3431 - 3438
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2007, Volume 104, Issue 3, pp. 979 - 984
Journal Article
Food and Function, ISSN 2042-6496, 5/2014, Volume 5, Issue 6, pp. 1241 - 1249
Journal Article
Leukemia, ISSN 0887-6924, 11/2017, Volume 31, Issue 11, pp. 2388 - 2397
Journal Article
Journal Article