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Free Radical Biology and Medicine, ISSN 0891-5849, 10/2016, Volume 99, pp. 87 - 98
Advanced age is associated with increased risk for cardiovascular disease and type 2 diabetes. A proposed central event is diminished amounts of nitric oxide... 
Hypertension | Angiotensin II receptors | Renin | NADPH oxidase | Nitric oxide | Aging | Endothelial dysfunction | Superoxide | Nitrite | Metabolic syndrome | NADPH-OXIDASE | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | HEART-FAILURE | REDUCES BLOOD-PRESSURE | AT RECEPTORS | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | CARDIOVASCULAR-DISEASE | SMOOTH-MUSCLE-CELLS | INORGANIC NITRATE | Angiotensin II - genetics | Angiotensin II - blood | Endothelium, Vascular - drug effects | Male | Mesenteric Arteries - drug effects | Cyclic GMP - blood | Hypertension - blood | Aging - genetics | Nitrites - blood | Hypertension - prevention & control | NADPH Oxidases - genetics | Blood Pressure - drug effects | Hypertension - genetics | Nitrates - blood | Glucose Tolerance Test | Receptors, Angiotensin - blood | Signal Transduction | Acetylcholine - pharmacology | Tissue Culture Techniques | NADPH Oxidases - antagonists & inhibitors | Gene Expression Regulation | Rats | NADPH Oxidases - blood | Mesenteric Arteries - metabolism | Receptors, Angiotensin - genetics | Nitric Oxide Synthase Type III - genetics | Rats, Sprague-Dawley | Hypertension - physiopathology | Nitrates - administration & dosage | Nitric Oxide Synthase Type III - blood | Animals | Endothelium, Vascular - metabolism | Dietary Supplements | Aging - metabolism | Oxidases | Type 2 diabetes | Dietary supplements | Glucose | Gene expression | Dextrose | Endothelium | Angiotensin | Physiological aspects | Acetylcholine | Insulin resistance | Cyclic guanylic acid
Journal Article
Journal Article
Clinical science (London, England : 1979), ISSN 0143-5221, 2015, Volume 129, Issue 6, pp. 505 - 513
Journal Article
Bioscience Reports, ISSN 0144-8463, 06/2018, Volume 38, Issue 3
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2014, Volume 280, Issue 3, pp. 443 - 454
Chronic arsenic exposure has been linked to elevated blood pressure and cardiovascular diseases, while statins reduce the incidence of cardiovascular disease... 
Atorvastatin | Lipid profile | Blood pressure | Arsenic | Rat | Redox signaling | OXIDATIVE STRESS | ENDOTHELIAL DYSFUNCTION | WEST-BENGAL | NITRIC-OXIDE SYNTHASE | ANGIOTENSIN-CONVERTING ENZYME | BLOOD-PRESSURE | SMOOTH-MUSCLE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | SUPEROXIDE-DISMUTASE | DRINKING-WATER | NADPH OXIDASES | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Sodium Compounds - metabolism | Glutathione Peroxidase - analysis | Rats, Wistar | Cholesterol - blood | Oxidative Stress - physiology | Male | Tyrosine - blood | Tyrosine - analogs & derivatives | Arsenites - toxicity | Pyrroles - administration & dosage | Hypertension - chemically induced | Heptanoic Acids - administration & dosage | Real-Time Polymerase Chain Reaction | Heptanoic Acids - pharmacology | Nitric Oxide - blood | Superoxide Dismutase - analysis | RNA, Messenger - genetics | Aorta, Thoracic - metabolism | NADPH Oxidases - blood | NADPH Oxidase 4 | Random Allocation | Nitric Oxide Synthase Type II - blood | Hypertension - metabolism | Arsenites - metabolism | Aorta, Thoracic - enzymology | Atorvastatin Calcium | Nitric Oxide Synthase Type III - blood | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Sodium Compounds - toxicity | Catalase - analysis | RNA, Messenger - chemistry | Oxidative Stress - drug effects | Antioxidants | Hypertension | Evaluation | RNA | Low density lipoproteins | Cardiovascular agents | Arsenic compounds | Antilipemic agents | CATALASE | HOMEOSTASIS | SODIUM | SUPEROXIDE DISMUTASE | ANTIOXIDANTS | CHOLESTEROL | AORTA | RATS | TRIGLYCERIDES | 60 APPLIED LIFE SCIENCES | ARSENIC | MESSENGER-RNA | GLUTATHIONE | BLOOD PRESSURE | INFLAMMATION | DRINKING WATER | HYPERTENSION | LIPOPROTEINS | MUSCLES | BLOOD
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2011, Volume 9, Issue 1, pp. 173 - 184
Aim: The aim of this study was to determine the effect of simultaneous hypertension and hypercholesterolemia on platelet activation, nitric oxide (NO)... 
atherosclerosis | integrin αIIbβ3 | NAD(P)H oxidase | reactive oxygen species | Reactive oxygen species | Integrin αIIbβ3 | Atherosclerosis | OXIDATIVE STRESS | RELEASE | SUPEROXIDE ANION | integrin alpha IIb beta 3 | AT RECEPTOR ANTAGONISTS | LDL | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | HEMATOLOGY | CONTRIBUTES | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Hypertension - drug therapy | Angiotensin II Type 1 Receptor Blockers - pharmacology | Hypertension - etiology | Hypertension - blood | Biphenyl Compounds - pharmacology | Time Factors | Lipids - blood | Mesocricetus | Blood Pressure - drug effects | Platelet Aggregation - drug effects | Protein Kinase C-delta - blood | Blood Platelets - drug effects | Cyclooxygenase 1 - blood | Disease Models, Animal | Nitric Oxide - blood | Cricetinae | Hypercholesterolemia - blood | Oxidation-Reduction | Reactive Oxygen Species - blood | Group IV Phospholipases A2 - blood | NADPH Oxidases - blood | Antioxidants - pharmacology | Integrin beta3 - blood | Hypertension - physiopathology | Cell Shape - drug effects | Nitric Oxide Synthase Type III - blood | Animals | Signal Transduction - drug effects | Blood Platelets - metabolism | P-Selectin - blood | Hypercholesterolemia - complications | Oxidative Stress - drug effects | Oxidases | Antioxidants | Hypertension | Hypercholesterolemia | Irbesartan | Analysis | Nitric oxide | Angiotensin | Hamsters | Integrins
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58481
Objective: The angiotensin II (AngII)-infused apolipoprotein E-deficient (ApoE(-/-)) mouse model is widely used to study atherosclerosis and abdominal aortic... 
ADHESION | MOLECULE EXPRESSION | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | DENSITY-LIPOPROTEIN | INCREASES | ATHEROSCLEROSIS | RECEPTOR | DEFICIENT MICE | DYSFUNCTION | BLOOD-PRESSURE | Angiotensin II - administration & dosage | Apolipoproteins E - deficiency | Endothelium, Vascular - drug effects | Male | Caveolae - drug effects | Aorta - metabolism | beta-Cyclodextrins - pharmacology | Hypertension - blood | Heart Rate - drug effects | Injections, Subcutaneous | Blood Pressure - drug effects | Aorta - physiopathology | Hypertension - genetics | Nitric Oxide - blood | Caveolin 1 - blood | Acetylcholine - pharmacology | Caveolae - metabolism | Aorta - drug effects | Endothelium, Vascular - physiopathology | Caveolin 1 - genetics | Nitric Oxide Synthase Type III - genetics | Hypertension - physiopathology | Mice, Knockout | Gene Expression Regulation - drug effects | Nitric Oxide Synthase Type III - blood | Animals | Endothelium, Vascular - metabolism | Apolipoproteins E - genetics | Mice | Vasodilation - drug effects | Development and progression | Genetic aspects | Apolipoproteins | Health aspects | Caveolins | Vasoconstriction | Caveolin-1 | Phosphorylation | Disease | Biology | Colorimetry | Carotid arteries | Blood | Western blotting | Proteins | Infusion | Apolipoprotein E | Chlorides | Rodents | Atherosclerosis | Phenylephrine | Aorta | Blood pressure | Angiotensin II | Hypertension | Caveolae | Caveolin | Contractility | Distilled water | Pharmacology | Bioavailability | Permeability | Dentistry | Muscle contraction | Nitric-oxide synthase | Endothelium | Medicine | Heart rate | Studies | Cyclodextrin | Diet | Nitric oxide | Arteriosclerosis | Coronary vessels | Angiotensin | Acetylcholine | Laboratory animals | Potassium
Journal Article
Circulation, ISSN 0009-7322, 12/2004, Volume 110, Issue 25, pp. 3849 - 3857
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 07/2013, Volume 62, Issue 1, pp. 203 - 208
Journal Article