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Circulation, ISSN 0009-7322, 03/2019, Volume 139, Issue 11, pp. 1354 - 1365
BACKGROUND:The morbidity and mortality of patients with functional mitral regurgitation (MR) remain high, but no pharmacological therapy has been proven... 
Receptors | Mitral valve insufficiency | Research | Drug therapy | Angiotensin
Journal Article
European Heart Journal, ISSN 0195-668X, 08/2015, Volume 36, Issue 30, pp. 1990 - 1997
Journal Article
Lancet, The, ISSN 0140-6736, 10/2012, Volume 380, Issue 9851, pp. 1387 - 1395
Journal Article
Journal Article
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Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5791 - 13
Angiotensin receptor blocker-neprilysin inhibitor (ARNi) therapy improves the prognosis of heart failure patients. However, the mechanisms remain unclear. This... 
HYPERTROPHY | AUGMENTATION | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | TACHYCARDIA | RABBIT MODEL | LCZ696 | DYSFUNCTION | CONTRIBUTES | EXPRESSION | LEFT-VENTRICULAR FUNCTION | Heart failure | Myocardial infarction | Contractility | Connective tissue growth factor | Beta blockers | Muscle contraction | Angiogenesis | Computed tomography | Perfusion | Fibrosis | Angiotensin | Myocardium | Neprilysin | Heart diseases
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 10/2013, Volume 94, Issue 4, pp. 445 - 448
Journal Article
American Heart Journal, ISSN 0002-8703, 05/2018, Volume 199, pp. 176 - 177
[...]although the dramatic benefits of ARNI therapy on clinical outcomes are well established, the impact of sacubitril/valsartan on mechanistic surrogate... 
MORTALITY | TRIAL | OMAPATRILAT | CARDIAC & CARDIOVASCULAR SYSTEMS | REDUCED EJECTION FRACTION | LCZ696 | ENALAPRIL | Heart failure | Mortality | Angiotensin | Biomarkers | Neprilysin | FDA approval | Cardiology | Drug therapy | Patients | Heart diseases | Drug dosages | Morbidity
Journal Article
Medicine, ISSN 0025-7974, 09/2019, Volume 98, Issue 39, p. e17296
Byline: Mingyue Zhao, Laboratory of Cardiovascular Diseases, Regenerative Medicine Research Center, West China Hospital; Yanguo Xin, Department of Cardiology,... 
Heart failure | Antihypertensive drugs | Usage | Drug therapy | Patient outcomes | Angiotensin II receptor blockers
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 1/2018, Volume 57, Issue 1, pp. 105 - 123
Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion... 
Medicine & Public Health | Angiotensin receptor–neprilysin inhibitor | Drug–drug interaction | Pharmacotherapy | Internal Medicine | Sacubitril/valsartan | Pharmacology/Toxicology | Pharmacokinetics
Journal Article