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chemistry, organic (73) 73
angucycline antibiotics (70) 70
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Organic Chemistry Frontiers, ISSN 2052-4110, 02/2019, Volume 6, Issue 3, pp. 399 - 404
Purmedermycin A (1) and purmedermycin B (2), which were isolated from Streptomyces sp. SS17A, feature a rearranged and reconstructed C/D/E ring formed by the... 
ANGUCYCLINE ANTIBIOTICS | CHEMISTRY, ORGANIC
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 15, pp. 1885 - 1888
A general synthetic strategy based on a protecting group-promoted CH arylation method was developed for total syntheses of anhydro-landomycinone (1),... 
REVISION | ORIGINALLY ASSIGNED STRUCTURE | DIRECT ARYLATION | NATURAL-PRODUCTS | BIOSYNTHESIS | ANGUCYCLINES | CHEMISTRY, MULTIDISCIPLINARY | SKELETON
Journal Article
Tetrahedron, ISSN 0040-4020, 02/2005, Volume 61, Issue 6, pp. 1551 - 1562
The λ -iodane [bis(trifluoroacetoxy)]iodobenzene (BTI)-mediated oxidative dearomatization of 2-alkoxyarenols with soft external carbon-based nucleophiles... 
Dearomatization | Angucyclines | Aquayamycin | Iodane | Cyclohexa-2,4-Dienones
Journal Article
Natural Product Research, ISSN 1478-6419, 2018, pp. 1 - 9
Stereospermum fimbriatum or locally known as "Chicha" is traditionally used for itchy skin, earache, stomachache and postpartum treatments. This study was... 
chicha | antibacterial | isolation | angucycline | Stereospermum fimbriatum
Journal Article
Tetrahedron, ISSN 0040-4020, 07/2019, Volume 75, Issue 30, pp. 4031 - 4041
A Pd(II)-catalyzed cascade synthesis of diverse polycyclic aromatic hydrocarbons via transient directing group strategy has been developed, involving the... 
Bioactive molecules | Palladium | Polycyclic aromatic hydrocarbons | Transient directing group | Cascade | ACTIVATION | ARYLATION | CHEMISTRY, ORGANIC | ALDEHYDES | ANGUCYCLINES | BENZALDEHYDES | SKELETON | FUNCTIONALIZATION | TETRANGULOL | CONSTRUCTION | CYCLIZATION
Journal Article
Natural Product Research, ISSN 1478-6419, 2019, pp. 1 - 7
A new (1, grincamycin L) and two known (2 and 3) angucycline derivatives were obtained from the fermentation of deepsea-derived Streptomyces lusitanus... 
multi-drug resistance | Deepsea-derived Streptomyces | antibiotics | angucycline
Journal Article
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 03/2019, Volume 17, Issue 10, pp. 2691 - 2704
Total syntheses of aquayamycin (3) and a number of analogues of angucycline antitumor antibiotic derhodinosylurdamycin A bearing various 2-deoxy sugar subunits... 
MICROORGANISMS | ANGUCYCLINE ANTIBIOTICS | GENE | URDAMYCINONE-B | METABOLIC PRODUCTS | CHEMISTRY, ORGANIC | STREPTOMYCES-FRADIAE
Journal Article
Tetrahedron, ISSN 0040-4020, 01/2018, Volume 74, Issue 1, pp. 12 - 18
The synthesis of the benz[ ]anthracene skeleton of the angucyclines is described. Key steps involve the Suzuki-Miyaura reaction, isomerization of an aromatic... 
Angucyclines | Benz[a]anthracenes | Isomerization | Metathesis | Suzuki-Miyaura reaction | BIOMIMETIC-TYPE SYNTHESIS | ANTIBIOTICS | METABOLITES | (+)-RUBIGINONE B-2 | QUINONES | ANALOG | CHEMISTRY, ORGANIC | REGIOCHEMICAL CONTROL | JUGLONE | TETRANGULOL | DERIVATIVES | Usage | Benzene | Quinone | Palladium | Catalysis | Methods
Journal Article
Saudi Pharmaceutical Journal, ISSN 1319-0164, 11/2019, Volume 27, Issue 7, pp. 907 - 913
In our previous studies, the production of four bioactive molecules by sp. PAL114 in complex ISP2 broth medium has been described. Three of these molecules... 
Angucycline antibiotics | L-Tryptophan | Streptomyces | Antimicrobial compounds | Synthetic medium
Journal Article
Biotechnology and Applied Biochemistry, ISSN 0885-4513, 07/2019, Volume 66, Issue 4, pp. 517 - 526
Sch47554 and Sch47555 are two angucyclines with antifungal activities against various yeasts and dermatophytes from Streptomyces sp. SCC‐2136. The sch gene... 
Sch47554 | Streptomyces | regulatory protein | antifungal agents | angucyclines | Anopheles | Genetic transcription | Genes | Antifungal agents | Blood proteins | Yeasts | Industrial production | Regulators | Yeast | Fungicides | Repressors | Transcription | Biosynthesis | Regulatory sequences | Disruption
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2018, Volume 24, Issue 60, pp. 15955 - 15964
Photoredox reactions of quinones are reviewed, that enable C−H bond oxidation at the vicinity of the excited quinone carbonyl and concomitant reduction of the... 
C−H functionalization | natural products | quinones | photochemistry | redox reaction | ANTIBIOTICS | MECHANISM | TRIMETHYL LOCK | URDAMYCINONE B | C-H functionalization | ANGUCYCLINES | CHEMISTRY, MULTIDISCIPLINARY | PHOTOREACTIONS | LIGHT-INDUCED REACTIONS | 1ST TOTAL-SYNTHESIS | PHOTOLYSIS | Quinone | Quinones | Utilities | Hydrogen bonds | Anthraquinones | Oxidation | Carbonyls
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2014, Volume 55, Issue 42, pp. 5771 - 5773
Two new angucycline compounds containing O-glycosylated 6-deoxy-α- -talose were isolated from sp. The compounds were elucidated based on spectroscopic methods... 
Angucyclines | 6-Deoxy-α-l-talose | Kitasatospora | Amycomycins | GLYCOSIDES | STREPTOMYCES SP | CHEMISTRY, ORGANIC | 6-Deoxy-alpha-L-talose | POLYSACCHARIDE
Journal Article
Planta Medica, ISSN 0032-0943, 2011, Volume 77, Issue 18, pp. 2057 - 2060
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 2/2019, Volume 103, Issue 4, pp. 1659 - 1665
Journal Article
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 2019, pp. 1 - 16
DNA gyrase enzyme has vital role in bacterial survival and can be considered as a potential drug target. Owing to the appearance of resistance to... 
molecular dynamics simulations | molecular docking analyses | structure-based virtual screening | StreptomeDB | DNA gyrase | Angucycline moiety
Journal Article
Angewandte Chemie-International Edition, ISSN 1433-7851, 02/2019, Volume 58, Issue 9, pp. 2809 - 2814
The angucyclines form the largest family of polycyclic aromatic polyketides, and have been studied extensively. Herein, we report the discovery of... 
Baeyer-Villiger oxidation | EXPLORE | ANTIBIOTICS | molecular networking | natural product | polyketide | NATURAL-PRODUCTS | BIOSYNTHESIS | angucycline | Polyketide | Molekulare Netzwerke | Angucycline | Naturstoffe | Baeyer-Villiger-Oxidation | Analysis | Drug discovery | Organic chemistry | Metabolomics | Polyketides
Journal Article
Marine drugs, ISSN 1660-3397, 11/2018, Volume 16, Issue 12, p. 470
Four angucycline glycosides including three new compounds landomycin N (1), galtamycin C (2) and vineomycin D (3), and a known homologue saquayamycin B (4),... 
Streptomyces | apoptosis | angucycline glycosides | saquayamycin | cytotoxicity | SMMC-7721 | ELUCIDATION | ANTIBIOTICS | CHEMISTRY, MEDICINAL | GALTAMYCIN-B | ANALOGS | SAQUAYAMYCIN-Z | ALKALOIDS
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 01/2016, Volume 55, Issue 4, pp. 1493 - 1497
Ruthenium(0) complexes modified by CyJohnPhos or RuPhos catalyze the successive C−C coupling of acetylenic aldehydes with α‐ketols to form [4+2] cycloadducts... 
natural products | ruthenium | cycloaddition | polyketides | hydrogenation | Catalysis | Acetylene - chemistry | Cycloaddition Reaction | Ruthenium - chemistry | Aldehydes - chemistry | Transfer Hydrogenation | Polyketide | Cycloaddition | Ruthenium | Angucycline
Journal Article
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