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Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7091, pp. 358 - 361
Journal Article
Journal Article
Materials Science & Engineering C, ISSN 0928-4931, 02/2017, Volume 71, pp. 954 - 964
In the present study, we designed Bicalutamide (BCT) and Hesperetin (HSP) co-loaded self nano-emulsifying drug delivery system (SNEDDS) to encounter the... 
Reactive oxygen species | Bicalutamide | Hesperetin | Antioxidant | Toxicity | Prostate cancer | MATERIALS SCIENCE, BIOMATERIALS | LYMPHATIC TRANSPORT | DRUG-DELIVERY | INDUCED APOPTOSIS | IMPROVED ORAL BIOAVAILABILITY | DROPLET SIZE | NANOPARTICLES | SYSTEMS SNEDDS | PROSTATE-CANCER | MCF-7 CELLS | ANTITUMOR EFFICACY | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Hesperidin - adverse effects | Nitriles - pharmacology | Anilides - adverse effects | Humans | Anilides - chemistry | Rats | Male | Tosyl Compounds - chemistry | Anilides - pharmacokinetics | Nitriles - pharmacokinetics | Rats, Sprague-Dawley | Tosyl Compounds - pharmacokinetics | Tosyl Compounds - pharmacology | Tosyl Compounds - adverse effects | Animals | Anilides - pharmacology | Hesperidin - chemistry | Nitriles - chemistry | Hesperidin - pharmacology | Nitriles - adverse effects | Hesperidin - pharmacokinetics | Prostatic Neoplasms - drug therapy | Drugs | Heat shock proteins | Drug delivery systems | Analysis | Vehicles | Clathrin | Fluorescence | Drug delivery | Optimization | Antioxidants | Endocytosis | Biocompatibility | Hepatotoxicity | Formulations | Thermogravimetric analysis | Lung diseases | Markers | Bioavailability | Fibrosis | In vivo methods and tests | Prostate | Cancer | Acute toxicity | Biochemical markers | Index Medicus | Encounters | Globules | Materials science | Nanostructure
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 238, Issue 2, pp. 150 - 159
Flutamide, a widely used nonsteroidal anti-androgen, but not its bioisostere bicalutamide, has been associated with idiosyncratic drug-induced liver injury.... 
Sod2 +/− mice | Mitochondria | Flutamide | Drug-induced liver injury (DILI) | Superoxide dismutase | Idiosyncratic drug toxicity | Bicalutamide | Hepatotoxicity | Sod2 | mice | METABOLITES | HETEROZYGOUS SOD2(+/-) MICE | BIOACTIVATION | IN-VITRO | MICROSOMES | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | TOXICOLOGY | Sod2(+/-) mice | SUPEROXIDE-DISMUTASE | CYANO ANALOG | Mitochondria - enzymology | Liver - pathology | Superoxide Dismutase - genetics | Liver - enzymology | Nitriles - pharmacology | Apoptosis - drug effects | Flutamide - toxicity | Hepatocytes - pathology | Male | Systems Biology | Tosyl Compounds - pharmacology | Dose-Response Relationship, Drug | Alanine Transaminase - drug effects | Liver - drug effects | Androgen Antagonists - toxicity | Hepatocytes - drug effects | Superoxide Dismutase - metabolism | Mice, Inbred C57BL | Mitochondria - drug effects | Mitochondria - pathology | Superoxide Dismutase - drug effects | Mice, Knockout | Necrosis - chemically induced | Animals | Anilides - pharmacology | Heterozygote | Mice | Alanine Transaminase - metabolism | Oxidative Stress - drug effects | Hepatocytes - enzymology | Drugs | Lactates | Analysis | Pharmacy | Liver | Mitochondrial DNA | Superoxide | Health aspects | Index Medicus | OXIDATION | LABELLING | PHOSPHORYLATION | MITOCHONDRIA | DEOXYURIDINE | TOXICITY | 60 APPLIED LIFE SCIENCES | STRESSES | NECROSIS | DOSES | LIVER | LIVER CELLS | MICE | HAZARDS
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 46, pp. 35567 - 35577
Polyglutamine expansion within the androgen receptor (AR) causes spinal and bulbar muscular atrophy (SBMA) and is associated with misfolded and aggregated... 
COACTIVATOR | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COOH-TERMINAL INTERACTION | PROSTATE-CANCER | LIGAND-BINDING DOMAIN | INDUCED DISEASE | TRANSGENIC MOUSE MODEL | IDENTIFICATION | ACTIVATION FUNCTION 2 | PHOSPHORYLATION SITES | Bulbo-Spinal Atrophy, X-Linked - genetics | Nitriles - pharmacology | Bulbo-Spinal Atrophy, X-Linked - pathology | Humans | Receptors, Androgen - metabolism | Testosterone - pharmacology | PC12 Cells | Tosyl Compounds - pharmacology | Motor Neurons - cytology | Protein Binding - drug effects | HEK293 Cells | Dihydrotestosterone - pharmacology | Receptors, Androgen - chemistry | Amino Acid Sequence | Cells, Cultured | Androgen Antagonists - pharmacology | Rats | Mice, Transgenic | Binding Sites - genetics | Bulbo-Spinal Atrophy, X-Linked - metabolism | Blotting, Western | Motor Neurons - metabolism | Two-Hybrid System Techniques | Animals | Receptors, Androgen - genetics | Androgens - pharmacology | Anilides - pharmacology | Trinucleotide Repeat Expansion - genetics | Mice | Mutation | Amino Acid Motifs - genetics | Microscopy, Fluorescence | Index Medicus | Cell culture | Motor neurons | Polyglutamine | Transcription | Androgen receptors | Toxicity | spinal and bulbar muscular atrophy | Neuromodulation | Molecular Bases of Disease | Androgen Receptor | Neurodegeneration | Motor Neuron Disease | Polyglutamine Disease | Protein Motifs | Protein Phosphorylation | Protein Folding
Journal Article
Science of the Total Environment, ISSN 0048-9697, 08/2018, Volume 633, pp. 1227 - 1236
Journal Article
ChemMedChem, ISSN 1860-7179, 11/2009, Volume 4, Issue 11, pp. 1930 - 1938
Journal Article