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1. Full Text NanoPET imaging of [18F]fluoromisonidazole uptake in experimental mouse tumours
by Wyss, Matthias T and Wyss, Matthias T and Honer, Michael and Honer, Michael and Schubiger, Pius A and Schubiger, Pius A and Ametamey, Simon M and Ametamey, Simon M
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 3/2006, Volume 33, Issue 3, pp. 311 - 318
Medicine | [ 18 F]Fluoromisonidazole | [ 18 F]Fluorodeoxyglucose | Tumour hypoxia | Murine tumour models | NanoPET | F]Fluoromisonidazole | F]Fluorodeoxyglucose | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Radiopharmaceuticals - pharmacokinetics | Nanotechnology - methods | Nanotechnology - instrumentation | Metabolic Clearance Rate | Misonidazole - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Positron-Emission Tomography - instrumentation | Equipment Design | Oxygen - metabolism | Feasibility Studies | Neoplasms, Experimental - diagnostic imaging | Cell Hypoxia | Tissue Distribution | Animals | Mice, Nude | Positron-Emission Tomography - veterinary | Female | Mice | Mice, Inbred BALB C | Neoplasms, Experimental - metabolism | Equipment Failure Analysis | Index Medicus
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2. Full Text Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
by Seaman, Steven and Zhu, Zhongyu and Saha, Saurabh and Zhang, Xiaoyan M and Yang, Mi Young and Hilton, Mary Beth and Morris, Karen and Szot, Christopher and Morris, Holly and Swing, Deborah A and Tessarollo, Lino and Smith, Sean W and Degrado, Sylvia and Borkin, Dmitry and Jain, Nareshkumar and Scheiermann, Julia and Feng, Yang and Wang, Yanping and Li, Jinyu and Welsch, Dean and DeCrescenzo, Gary and Chaudhary, Amit and Zudaire, Enrique and Klarmann, Kimberly D and Keller, Jonathan R and Dimitrov, Dimiter S and St. Croix, Brad
Cancer cell, ISSN 1535-6108, 04/2017, Volume 31, Issue 4, pp. 501 - 515.e8
ADC | P-glycoprotein | endothelium | P-gp | PBD | Abcb1 | angiogenesis | cancer | TEM | B7H3 | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Blood Vessels - metabolism | Blood Vessels - pathology | Humans | Endothelium, Vascular - drug effects | Male | B7 Antigens - immunology | Immunoconjugates - immunology | Immunoconjugates - pharmacology | Neoplasms - therapy | B7 Antigens - genetics | Female | Antineoplastic Agents - pharmacology | Molecular Targeted Therapy - methods | Rabbits | Benzodiazepines - pharmacology | Antineoplastic Agents - immunology | Mice, Inbred C57BL | Mice, Transgenic | Neoplasms - blood supply | B7 Antigens - metabolism | Mice, Knockout | Pyrroles - pharmacology | Animals | Cell Line, Tumor | Endothelium, Vascular - pathology | Neoplasms - pathology | Oligopeptides - pharmacology | Viral antibodies | Medical research | Ablation (Surgery) | Biological products | Blood-vessels | Stem cells | Medicine, Experimental | Antibodies | Genetic engineering | Metastasis | Tumors | Cancer | Cells | Endothelium | Index Medicus | MMAE | vasculature | CD276
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3. Full Text CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms
by Li, Xian-Yang and Das, Indrajit and Lepletier, Ailin and Addala, Venkateswar and Bald, Tobias and Stannard, Kimberley and Barkauskas, Deborah and Liu, Jing and Aguilera, Amelia Roman and Takeda, Kazuyoshi and Braun, Matthias and Nakamura, Kyohei and Jacquelin, Sebastien and Lane, Steven W and Teng, Michele W.L and Dougall, William C and Smyth, Mark J
The Journal of clinical investigation, ISSN 0021-9738, 06/2018, Volume 128, Issue 6, pp. 2613 - 2625
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | CD8-Positive T-Lymphocytes - pathology | Neoplasm Proteins - immunology | CTLA-4 Antigen - genetics | Killer Cells, Natural - pathology | CTLA-4 Antigen - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Mice, Knockout | Neoplasms, Experimental - pathology | Animals | Receptors, Virus - deficiency | Neoplasms, Experimental - immunology | Neoplasms, Experimental - genetics | Cell Line, Tumor | Killer Cells, Natural - immunology | Receptors, Virus - immunology | Mice | Mice, Inbred BALB C | Neoplasm Proteins - deficiency | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Immunosuppression | Immunoglobulins | Care and treatment | Receptors | Oncology, Experimental | Viruses | Research | Health aspects | Cancer | Index Medicus | Abridged Index Medicus
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4. Full Text Maintaining tumor heterogeneity in patient-derived tumor xenografts
by Cassidy, John W and Caldas, Carlos and Bruna, Alejandra
Cancer research (Chicago, Ill.), ISSN 0008-5472, 08/2015, Volume 75, Issue 15, pp. 2963 - 2968
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms, Experimental - pathology | Xenograft Model Antitumor Assays | Animals | Heterografts | Humans | Tumor Microenvironment | Mice | Disease Models, Animal | Index Medicus | Tumour Microenvironment | Patient-Derived Tumour Xenograft | Clonal dynamics | Tumour Heterogeneity | Cancer Associated Fibroblasts | Humanized mice
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5. Full Text VEGF-A modulates expression of inhibitory checkpoints on CD8+ + T cells in tumors
by Voron, Thibault and Colussi, Orianne and Marcheteau, Elie and Pernot, Simon and Nizard, Mevyn and Pointet, Anne-Laure and Latreche, Sabrina and Bergaya, Sonia and Benhamouda, Nadine and Tanchot, Corinne and Stockmann, Christian and Combe, Pierre and Berger, Anne and Zinzindohoue, Franck and Yagita, Hideo and Tartour, Eric and Taieb, Julien and Terme, Magali
The Journal of experimental medicine, ISSN 0022-1007, 2015, Volume 212, Issue 2, pp. 139 - 148
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Gene Expression Profiling | Vascular Endothelial Growth Factor A - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Neoplasms - genetics | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Disease Models, Animal | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | CTLA-4 Antigen - genetics | Lymphocytes, Tumor-Infiltrating - drug effects | Animals | Signal Transduction - drug effects | Neoplasms - immunology | CD8-Positive T-Lymphocytes - drug effects | Protein Binding | Mice | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Programmed Cell Death 1 Receptor - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Brief Definitive Report
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6. Full Text Expansion and Activation of CD103+ Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
by Salmon, Hélène and Idoyaga, Juliana and Rahman, Adeeb and Leboeuf, Marylène and Remark, Romain and Jordan, Stefan and Casanova-Acebes, Maria and Khudoynazarova, Makhzuna and Agudo, Judith and Tung, Navpreet and Chakarov, Svetoslav and Rivera, Christina and Hogstad, Brandon and Bosenberg, Marcus and Hashimoto, Daigo and Gnjatic, Sacha and Bhardwaj, Nina and Palucka, Anna Karolina and Brown, Brian D and Brody, Joshua and Ginhoux, Florent and Merad, Miriam
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2016, Volume 44, Issue 4, pp. 924 - 938
Life Sciences & Biomedicine | Immunology | Science & Technology | Poly I-C - pharmacology | Dendritic Cells - immunology | Mice, Inbred C57BL | Integrin alpha Chains - metabolism | Antigen Presentation - immunology | Antigens, CD - metabolism | Mice, Knockout | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Animals | B7-H1 Antigen - antagonists & inhibitors | Melanoma, Experimental - immunology | Cell Line, Tumor | Dendritic Cells - cytology | CD8-Positive T-Lymphocytes - immunology | fms-Like Tyrosine Kinase 3 - pharmacology | Antigens | Medical research | Flow cytometry | Funding | Cloning | Melanoma | T cell receptors | Experiments | Lymphocytes | Expansion | Tumors | Cancer | Apoptosis | Index Medicus
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7. Full Text Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
by Duraiswamy, Jaikumar and Kaluza, Karen M and Freeman, Gordon J and Coukos, George
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3591 - 3603
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | T-Lymphocytes, Regulatory - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antibodies, Blocking - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Neoplasms, Experimental - pathology | Flow Cytometry | T-Lymphocytes - metabolism | Neoplasms, Experimental - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Cytokines - immunology | Cytokines - metabolism | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Neoplasms, Experimental - therapy | CTLA-4 Antigen - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Programmed Cell Death 1 Receptor - metabolism | Combined Modality Therapy | CTLA-4 Antigen - immunology | B7-H1 Antigen - immunology | Cancer Vaccines - immunology | B7-H1 Antigen - metabolism | Animals | Antibodies, Blocking - immunology | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Tumor Burden - immunology | Index Medicus
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8. Full Text Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
by Kurtulus, Sema and Madi, Asaf and Escobar, Giulia and Klapholz, Max and Nyman, Jackson and Christian, Elena and Pawlak, Mathias and Dionne, Danielle and Xia, Junrong and Rozenblatt-Rosen, Orit and Kuchroo, Vijay K and Regev, Aviv and Anderson, Ana C
Immunity (Cambridge, Mass.), ISSN 1074-7613, 01/2019, Volume 50, Issue 1, pp. 181 - 194.e6
checkpoint blockade | memory | immunotherapy | single-cell | exhaustion | CD8+ T cell | cancer | PD-1 | dysfunction | Tim-3 | CD8 | T cell | Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocyte Subsets - immunology | Cell Proliferation | Hepatocyte Nuclear Factor 1-alpha - genetics | Antigens, Neoplasm - immunology | Humans | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Transcriptome | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - drug effects | Hepatocyte Nuclear Factor 1-alpha - metabolism | Hepatitis A Virus Cellular Receptor 2 - antagonists & inhibitors | Animals | Melanoma, Experimental | CD8-Positive T-Lymphocytes - drug effects | Immunotherapy | Neoplasms, Experimental - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Immunologic Memory - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Memory cells | Immunoglobulins | Immunological memory | Transcription factors | Tumor-infiltrating lymphocytes | Transcription | PD-1 protein | CD8 antigen | Effector cells | Principal components analysis | Lymphocytes T | Gene expression | Ribonucleic acid--RNA | Immune checkpoint | Lymphocytes | Precursors | Population | Software | Cancer | Tumors | Index Medicus | CD8+ T cell
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