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1. Full Text Concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of Helicobacter pylori : a multicentre, open-label, randomised trial
by Liou, Jyh-Ming, MD and Fang, Yu-Jen, MD and Chen, Chieh-Chang, MD and Bair, Ming-Jong, MD and Chang, Chi-Yang, MD and Lee, Yi-Chia, Prof and Chen, Mei-Jyh, MD and Chen, Chien-Chuan, MD and Tseng, Cheng-Hao, MD and Hsu, Yao-Chun, MD and Lee, Ji-Yuh, MD and Yang, Tsung-Hua, MD and Luo, Jiing-Chyuan, Prof and Chang, Chun-Chao, MD and Chen, Chi-Yi, MD and Chen, Po-Yueh, MD and Shun, Chia-Tung, Prof and Hsu, Wen-Feng, MD and Hu, Wen-Hao, MD and Chen, Yen-Nien, MD and Sheu, Bor-Shyang, Prof and Lin, Jaw-Town, Prof and Wu, Jeng-Yih, MD and El-Omar, Emad M, Prof and Wu, Ming-Shiang, Prof and Taiwan Gastrointestinal Dis and Taiwan Gastrointestinal Disease and Helicobacter Consortium
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10058, pp. 2355 - 2365
Summary Background Whether concomitant therapy is superior to bismuth quadruple therapy or 14-day triple therapy for the first-line treatment of Helicobacter... 
Internal Medicine | CLARITHROMYCIN | ESOMEPRAZOLE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | EFFICACY | GASTRIC-CANCER | RESISTANCE | SEQUENTIAL THERAPY | INFECTION | ERADICATION | METRONIDAZOLE | Humans | Middle Aged | Helicobacter pylori - drug effects | Male | Antacids - therapeutic use | Anti-Bacterial Agents - therapeutic use | Proton Pump Inhibitors - administration & dosage | Metronidazole - therapeutic use | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Organometallic Compounds - therapeutic use | Female | Urea - metabolism | Amoxicillin - administration & dosage | Lansoprazole - administration & dosage | Drug Administration Schedule | Metronidazole - administration & dosage | Breath Tests | Tetracycline - therapeutic use | Clarithromycin - therapeutic use | Proton Pump Inhibitors - therapeutic use | Amoxicillin - therapeutic use | Taiwan | Drug Therapy, Combination - statistics & numerical data | Lansoprazole - therapeutic use | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Tetracycline - administration & dosage | Organometallic Compounds - administration & dosage | Clinical trials | Medical colleges | Helicobacter infections | Care and treatment | Helicobacter pylori | Antiulcer drugs | Analysis | Bacteria | Bacterial infections | Antibiotics | Drug resistance | Drug therapy
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2. Full Text Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study
by Murakami, Kazunari and Sakurai, Yuuichi and Shiino, Madoka and Funao, Nobuo and Nishimura, Akira and Asaka, Masahiro
Gut, ISSN 0017-5749, 09/2016, Volume 65, Issue 9, pp. 1439 - 1446
ObjectiveThe objective of this study was to assess the efficacy, safety and tolerability of vonoprazan, a novel potassium-competitive acid blocker, as a... 
antibiotic therapy | clinical trials | Helicobacter pylori infection | helicobacter pylori - treatment | CLARITHROMYCIN | LANSOPRAZOLE | MULTICENTER | MANAGEMENT | CLINICAL-TRIAL | PHARMACOKINETICS | JAPAN | INFECTION | MONOFUMARATE TAK-438 | GASTROENTEROLOGY & HEPATOLOGY | AMOXICILLIN | Humans | Middle Aged | Helicobacter Infections - complications | Helicobacter pylori - drug effects | Male | Drug Monitoring - methods | Proton Pump Inhibitors - administration & dosage | Pyrroles - administration & dosage | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Metronidazole - adverse effects | Peptic Ulcer - diagnosis | Pyrroles - adverse effects | Adult | Female | Amoxicillin - administration & dosage | Anti-Bacterial Agents - adverse effects | Helicobacter Infections - diagnosis | Lansoprazole - administration & dosage | Proton Pump Inhibitors - adverse effects | Double-Blind Method | Drug Administration Schedule | Clarithromycin - adverse effects | Metronidazole - administration & dosage | Treatment Outcome | Drug Therapy, Combination - methods | Lansoprazole - adverse effects | Sulfonamides - adverse effects | Amoxicillin - adverse effects | Helicobacter pylori - isolation & purification | Anti-Bacterial Agents - administration & dosage | Peptic Ulcer - drug therapy | Breath Tests - methods | Peptic Ulcer - etiology | Sulfonamides - administration & dosage | Usage | Safety and security measures | Research | Helicobacter pylori | Antacids | Helicobacter Pylori | HELICOBACTER PYLORI - TREATMENT | CLINICAL TRIALS | 1506 | ANTIBIOTIC THERAPY | HELICOBACTER PYLORI INFECTION
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3. Full Text Gitelman's syndrome with hyperphosphatemia, effectively responding to single oral magnesium oxide administration A case report
by Miya, A and Nakamura, A and Kameda, H and Nozu, K and Miyoshi, H and Atsumi, T
MEDICINE, ISSN 0025-7974, 07/2019, Volume 98, Issue 28, p. e16408
Rationale: The Gitelman's syndrome (GS) is characterized by metabolic alkalosis, hypokalemia, hypomagnesemia, and hypocalciuria. However, the involvement of... 
parathyroid hormone | MEDICINE, GENERAL & INTERNAL | HORMONE | hyperphosphatemia | DISEASE | hypomagnesemia | COTRANSPORTER GENE | Gitelman's syndrome | MUTATIONS | hypocalciuric hypocalcemia | BARTTERS-SYNDROME | Antacids - therapeutic use | Hyperphosphatemia - complications | Gitelman Syndrome - drug therapy | Administration, Oral | Magnesium Oxide - therapeutic use | Humans | Gitelman Syndrome - complications | Adult | Female | Hyperphosphatemia - drug therapy | Hyperphosphatemia - genetics | Gitelman Syndrome - genetics | Case studies | Usage | Genetic disorders | Magnesium oxide | Phosphorus imbalance | Kidney diseases | Drug therapy
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4. Full Text Helicobacter Pylori First-Line and Rescue Treatments in the Presence of Penicillin Allergy
by Gisbert, Javier P and Barrio, Jesús and Modolell, Inés and Molina-Infante, Javier and Aisa, Angeles Perez and Castro-Fernández, Manuel and Rodrigo, Luis and Cosme, Angel and Gisbert, Jose Luis and Fernández-Bermejo, Miguel and Marcos, Santiago and Marín, Alicia C and McNicholl, Adrián G
Digestive Diseases and Sciences, ISSN 0163-2116, 2/2015, Volume 60, Issue 2, pp. 458 - 464
Helicobacter pylori eradication is a challenge in penicillin allergy.To assess the efficacy and safety of first-line and rescue treatments in patients allergic... 
Biochemistry, general | Levofloxacin | Allergy | Quinolone | Oncology | Eradication | Allergic | Transplant Surgery | Medicine & Public Health | Helicobacter pylori | Hepatology | Gastroenterology | Penicillin | Bismuth | CLARITHROMYCIN | ANTIBIOTIC-RESISTANCE | QUADRUPLE THERAPY | PROTON PUMP INHIBITOR | TRIPLE THERAPY | INFECTION | METRONIDAZOLE | GASTROENTEROLOGY & HEPATOLOGY | TREATMENT FAILURE | Predictive Value of Tests | Bismuth - administration & dosage | Prospective Studies | Humans | Middle Aged | Salvage Therapy | Helicobacter pylori - drug effects | Male | Rifabutin - administration & dosage | Proton Pump Inhibitors - administration & dosage | Time Factors | Antacids - adverse effects | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Penicillins - adverse effects | Female | Anti-Bacterial Agents - adverse effects | Helicobacter Infections - diagnosis | Drug Therapy, Combination | Levofloxacin - administration & dosage | Drug Hypersensitivity - etiology | Proton Pump Inhibitors - adverse effects | Drug Administration Schedule | Metronidazole - administration & dosage | Omeprazole - administration & dosage | Breath Tests | Treatment Outcome | Spain | Medication Adherence | Helicobacter pylori - isolation & purification | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Tetracycline - administration & dosage | Helicobacter Infections - microbiology | Urea | Antibacterial agents | Allergic reaction
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5. Full Text Helicobacter pylori second‐line rescue therapy with levofloxacin‐ and bismuth‐containing quadruple therapy, after failure of standard triple or non‐bismuth quadruple treatments
by Gisbert, J. P and Romano, M and Gravina, A. G and Solís‐Muñoz, P and Bermejo, F and Molina‐Infante, J and Castro‐Fernández, M and Ortuño, J and Lucendo, A. J and Herranz, M and Modolell, I and del Castillo, F and Gómez, J and Barrio, J and Velayos, B and Gómez, B and Domínguez, J. L and Miranda, A and Martorano, M and Algaba, A and Pabón, M and Angueira, T and Fernández‐Salazar, L and Federico, A and Marín, A. C and McNicholl, A. G
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 04/2015, Volume 41, Issue 8, pp. 768 - 775
BackgroundThe most commonly used second-line Helicobacter pylori eradication regimens are bismuth-containing quadruple therapy and levofloxacin-containing... 
CLARITHROMYCIN | SUBCITRATE | METAANALYSIS | EFFICACY | RESISTANCE | RANDOMIZED-TRIAL | PHARMACOLOGY & PHARMACY | SEQUENTIAL THERAPY | INFECTION | ERADICATION | GASTROENTEROLOGY & HEPATOLOGY | CLINICAL-PRACTICE | Bismuth - administration & dosage | Prospective Studies | Esomeprazole - administration & dosage | Humans | Middle Aged | Male | Urea - analysis | Bismuth - therapeutic use | Esomeprazole - therapeutic use | Antacids - therapeutic use | Anti-Bacterial Agents - therapeutic use | Proton Pump Inhibitors - administration & dosage | Helicobacter Infections - drug therapy | Levofloxacin - therapeutic use | Adult | Female | Amoxicillin - administration & dosage | Drug Therapy, Combination | Levofloxacin - administration & dosage | Breath Tests | Proton Pump Inhibitors - therapeutic use | Antidiarrheals - therapeutic use | Amoxicillin - therapeutic use | Aged | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Helicobacter pylori | Levofloxacin | Urea
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6. Full Text Efficacy and Safety of Quinolone-Containing Rescue Therapies After the Failure of Non-Bismuth Quadruple Treatments for Helicobacter pylori Eradication: Systematic Review and Meta-Analysis
by Marin, Alicia C and Nyssen, Olga P and McNicholl, Adrian G and Gisbert, Javier P
Drugs, ISSN 0012-6667, 05/2017, Volume 77, Issue 7, pp. 765 - 776
Background Anti-Helicobacter pylori eradication treatment fails in a significant percentage of cases. Although this percentage has been reduced to 5-15% with... 
CLARITHROMYCIN | STANDARD TRIPLE | CONCOMITANT THERAPY | ARTICLE | PROTON-PUMP INHIBITOR | CONTAINING TRIPLE THERAPY | RESISTANCE | LEVOFLOXACIN TRIPLE | PHARMACOLOGY & PHARMACY | INFECTION | TOXICOLOGY | AMOXICILLIN | Proton Pump Inhibitors - adverse effects | Bismuth - administration & dosage | Clarithromycin - adverse effects | Humans | Helicobacter pylori - drug effects | Fluoroquinolones - adverse effects | Quinolones - administration & dosage | Quinolones - adverse effects | Proton Pump Inhibitors - administration & dosage | Antacids - adverse effects | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Levofloxacin - therapeutic use | Amoxicillin - adverse effects | Amoxicillin - administration & dosage | Drug Therapy, Combination | Antacids - administration & dosage | Levofloxacin - administration & dosage | Fluoroquinolones - administration & dosage | Helicobacter Infections - microbiology | Levofloxacin - adverse effects | Care and treatment | Usage | Dosage and administration | Helicobacter pylori | Drug therapy | Quinolones | Therapy | Levofloxacin | Sensitivity analysis | Effectiveness | Bias | Liver | Systematic review | Infections | Moxifloxacin | Studies | Motivation | Antibiotics | Quality | Amoxicillin | Bismuth | Bacteria | Clinical medicine | Safety | Gastrointestinal surgery | Failure
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7. Full Text Empirical rescue therapy after Helicobacter pylori treatment failure: A 10-year single-centre study of 500 patients
by Gisbert, J.P and Gisbert, J.-L and Marcos, S and Jimenez-Alonso, I and Moreno-Otero, R and Pajares, J.M
Alimentary Pharmacology and Therapeutics, ISSN 0269-2813, 02/2008, Volume 27, Issue 4, pp. 346 - 354
Background Several 'rescue' therapies have been recommended to eradicate Helicobacter pylori, but they still fail in >20% of the cases, and these patients... 
UNITED-STATES | DUODENAL-ULCER | PROTON PUMP INHIBITOR | VS. QUADRUPLE THERAPY | 2ND-LINE TREATMENT | ANTIBIOTIC-RESISTANCE | RANITIDINE BISMUTH CITRATE | TRIPLE THERAPY | PHARMACOLOGY & PHARMACY | INFECTED PATIENTS | GASTROENTEROLOGY & HEPATOLOGY | CLINICAL-PRACTICE | Prospective Studies | Humans | Middle Aged | Helicobacter pylori - drug effects | Rifabutin - administration & dosage | Antacids - therapeutic use | Metronidazole - therapeutic use | Helicobacter Infections - drug therapy | Treatment Failure | Organometallic Compounds - therapeutic use | Amoxicillin - administration & dosage | Drug Therapy, Combination | Ranitidine - therapeutic use | Anti-Ulcer Agents - therapeutic use | Omeprazole - therapeutic use | Metronidazole - administration & dosage | Omeprazole - administration & dosage | Breath Tests | Tetracycline - therapeutic use | Anti-Infective Agents - therapeutic use | Anti-Ulcer Agents - administration & dosage | Anti-Infective Agents - administration & dosage | Amoxicillin - therapeutic use | Rifabutin - therapeutic use | Helicobacter pylori - isolation & purification | Ranitidine - administration & dosage | Antacids - administration & dosage | Tetracycline - administration & dosage | Helicobacter Infections - microbiology | Organometallic Compounds - administration & dosage | Medicine, Experimental | Medical research | Helicobacter pylori | Analysis
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8. Full Text Effect of metal-cation antacids on the pharmacokinetics of 1200 mg raltegravir
by Krishna, Rajesh and East, Lilly and Larson, Patrick and Valiathan, Chandni and Butterfield, Kristin and Teng, Yang and Hernandez-Illas, Martha
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 11/2016, Volume 68, Issue 11, pp. 1359 - 1365
Objectives Raltegravir is a human immunodeficiency virus (HIV)-1 integrase strand transfer inhibitor currently marketed at a dose of 400 mg twice daily (BID).... 
interaction | pharmacokinetics | calcium carbonate | aluminium and magnesium hydroxide | once-daily | ACID-REDUCING AGENTS | THERAPY | VOLUNTEERS | PHARMACOLOGY & PHARMACY | HIV-INTEGRASE INHIBITOR | Raltegravir Potassium - adverse effects | Area Under Curve | Magnesium - administration & dosage | Humans | Middle Aged | Raltegravir Potassium - administration & dosage | Male | Metabolic Clearance Rate | Aluminum Hydroxide - administration & dosage | HIV Integrase Inhibitors - administration & dosage | Drug Interactions | Polypharmacy | Antacids - adverse effects | HIV Infections - diagnosis | Adult | Female | Calcium Carbonate - administration & dosage | Magnesium - adverse effects | Raltegravir Potassium - pharmacokinetics | Drug Administration Schedule | Administration, Oral | HIV Infections - virology | HIV Integrase Inhibitors - pharmacokinetics | Magnesium Hydroxide - adverse effects | Calcium Carbonate - adverse effects | Aluminum Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | HIV Integrase Inhibitors - adverse effects | Raltegravir Potassium - blood | HIV Infections - drug therapy | HIV Integrase Inhibitors - blood | Antacids - administration & dosage | Drug Combinations | Urine | Antiviral agents | Analysis | Electrocardiogram | Calcium carbonate | Electrocardiography | Magnesium hydroxide | HIV (Viruses) | Human immunodeficiency virus--HIV | Antacids | Magnesium
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9. Full Text Berberine containing quadruple therapy for initial Helicobacter pylori eradication An open-label randomized phase IV trial
by Zhang, D and Ke, L and Ni, Z and Chen, Y and Zhang, LH and Zhu, SH and Li, CJ and Shang, L and Liang, J and Shi, YQ
MEDICINE, ISSN 0025-7974, 08/2017, Volume 96, Issue 32, p. e7697
Background: Due to increasing antimicrobial resistance, a bismuth-based quadruple regimen has been recommended as an alternative first-line therapy for... 
MANAGEMENT | CHINA | SEQUENTIAL THERAPY | HERBAL MEDICINES | berberine | CONSENSUS REPORT | MEDICINE, GENERAL & INTERNAL | Helicobacter pylori | GASTRIC-CANCER | eradication | PROGRESS | TRIPLE THERAPY | INFECTION | quadruple therapy | bismuth | Berberine - administration & dosage | Bismuth - administration & dosage | Age Factors | Esomeprazole - administration & dosage | Humans | Middle Aged | Helicobacter pylori - drug effects | Male | Bismuth - therapeutic use | Bismuth - adverse effects | Antacids - therapeutic use | Anti-Bacterial Agents - therapeutic use | Proton Pump Inhibitors - administration & dosage | Antacids - adverse effects | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Adult | Female | Amoxicillin - administration & dosage | Anti-Bacterial Agents - adverse effects | Drug Therapy, Combination | Body Mass Index | Severity of Illness Index | Breath Tests | Sex Factors | Berberine - therapeutic use | Berberine - adverse effects | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Helicobacter infections | Usage | Cancer patients | Care and treatment | Drug therapy | Gastrectomy
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10. Full Text Randomised clinical trial: addition of alginate‐antacid (Gaviscon Double Action) to proton pump inhibitor therapy in patients with breakthrough symptoms
by Coyle, C and Crawford, G and Wilkinson, J and Thomas, S. J and Bytzer, P
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 06/2017, Volume 45, Issue 12, pp. 1524 - 1533
Background: Symptomatic breakthrough in proton pump inhibitor (PPI)-treated gastro-oesophageal reflux disease (GERD) patients is a common problem with a range... 
GERD | PRIMARY-CARE | PROTECTION | HEARTBURN | GASTROESOPHAGEAL-REFLUX DISEASE | REGURGITATION | ESOPHAGEAL MUCOSAL INTEGRITY | ACID POCKET | PHARMACOLOGY & PHARMACY | QUALITY-OF-LIFE | QUESTIONNAIRE | GASTROENTEROLOGY & HEPATOLOGY | Sodium Bicarbonate - adverse effects | Alginates - adverse effects | Humans | Middle Aged | Male | Sodium Bicarbonate - administration & dosage | Aluminum Hydroxide - administration & dosage | Breakthrough Pain - drug therapy | Proton Pump Inhibitors - administration & dosage | Antacids - adverse effects | Adult | Female | Gastroesophageal Reflux - drug therapy | Proton Pump Inhibitors - adverse effects | Double-Blind Method | Anti-Ulcer Agents - adverse effects | Treatment Outcome | Heartburn - drug therapy | Anti-Ulcer Agents - administration & dosage | Silicic Acid - administration & dosage | Alginates - administration & dosage | Aluminum Hydroxide - adverse effects | Silicic Acid - adverse effects | Aged | Antacids - administration & dosage | Drug Combinations | Heart | Protons | Intervention | Gastroesophageal reflux | Therapy | Dyspepsia | Alginic acid | Medical services | Clinical trials | Alginates | Patients | Esophagus | Reduction | Randomization | Inhibitors | Regurgitation | Meals
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11. Full Text Randomized clinical trial: a double-blind, placebo-controlled study to assess the clinical efficacy and safety of alginate–antacid (Gaviscon Double Action) chewable tablets in patients with gastro-oesophageal reflux disease
by Wilkinson, Joanne and Wade, Alan and Thomas, S Jane and Jenner, Bartosz and Hodgkinson, Victoria and Coyle, Cathal
European Journal of Gastroenterology & Hepatology, ISSN 0954-691X, 01/2019, Volume 31, Issue 1, pp. 86 - 93
BACKGROUNDThe alginate–antacid Gaviscon Double Action (Gaviscon DA) has a combined acid-neutralizing and reflux-suppressing action. Response to treatment in a... 
double-blind method | alginates | gastroesophageal reflux | dyspepsia | adult | heartburn | humans | tablets | PROTECTION | SYMPTOMS | PREVALENCE | IMPACT | PRIMARY-CARE | THERAPY | FUNCTIONAL DYSPEPSIA | ACID POCKET | OVERLAP | GASTROENTEROLOGY & HEPATOLOGY | Sodium Bicarbonate - adverse effects | Gastroesophageal Reflux - diagnosis | Heartburn - physiopathology | Tablets | Alginates - adverse effects | Gastroesophageal Reflux - physiopathology | Humans | Middle Aged | Male | Sodium Bicarbonate - administration & dosage | Aluminum Hydroxide - administration & dosage | Patient Satisfaction | Time Factors | Antacids - adverse effects | Adult | Female | Surveys and Questionnaires | Gastroesophageal Reflux - drug therapy | Double-Blind Method | Administration, Oral | Europe | Heartburn - diagnosis | Mastication | Treatment Outcome | Heartburn - drug therapy | Remission Induction | Silicic Acid - administration & dosage | Alginates - administration & dosage | Aluminum Hydroxide - adverse effects | Silicic Acid - adverse effects | Aged | Antacids - administration & dosage | Drug Combinations | Gastroesophageal reflux | Treatment outcome | Care and treatment | Safety and security measures | Patient outcomes | Analysis | Dosage and administration | Research | Comparative analysis | Antacids
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12. Full Text Triple vs. quadruple therapy for treating Helicobacter pylori infection: A meta-analysis
by Gené, E and Calvet, X and Azagra, R and Gisbert, J.P
Alimentary Pharmacology and Therapeutics, ISSN 0269-2813, 05/2003, Volume 17, Issue 9, pp. 1137 - 1143
Triple therapy (proton pump inhibitor, clarithromycin and amoxicillin or an imidazole) is the first-line treatment for Helicobacter pylori infection. However,... 
Bismuth - administration & dosage | Proton Pump Inhibitors | Humans | Metronidazole - administration & dosage | Drug Resistance, Bacterial | Randomized Controlled Trials as Topic | Drug Therapy, Combination - administration & dosage | Helicobacter pylori | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Amoxicillin - administration & dosage | Ditiocarb - administration & dosage | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Tetracycline - administration & dosage
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13. Full Text Impact of Acid‐Reducing Agents on the Pharmacokinetics of Palbociclib, a Weak Base With pH‐Dependent Solubility, With Different Food Intake Conditions
by Sun, Wan and Klamerus, Karen J and Yuhas, Lisa M and Pawlak, Sylvester and Plotka, Anna and O'Gorman, Melissa and Kirkovsky, Leonid and Kosa, Maha and Wang, Diane
Clinical Pharmacology in Drug Development, ISSN 2160-763X, 11/2017, Volume 6, Issue 6, pp. 614 - 626
Palbociclib free base capsule is a weak base drug with highly pH‐dependent solubility. In vitro and in vivo studies evaluated the impact of acid‐reducing... 
free base capsule | pH‐dependent solubility | histamine‐2 receptor antagonist | acid‐reducing agent | local antacid | pharmacokinetics | fed condition | palbociclib | proton pump inhibitor | fast condition | pH-dependent solubility | acid-reducing agent | histamine-2 receptor antagonist | RABEPRAZOLE | INTRAGASTRIC ACIDITY | ANTICANCER AGENTS | KINASE 4/6 | MIXED MICELLES | BIOAVAILABILITY | SELECTIVE INHIBITOR | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | GASTRIC PH | DRUG-DRUG INTERACTIONS | Piperazines - administration & dosage | Proton Pump Inhibitors - pharmacology | Area Under Curve | Histamine H2 Antagonists - pharmacology | Pyridines - chemistry | Humans | Middle Aged | Bile Acids and Salts - chemistry | Pyridines - pharmacokinetics | Male | Piperazines - chemistry | Young Adult | Histamine H2 Antagonists - administration & dosage | Protein Kinase Inhibitors - chemistry | Drug Interactions | Proton Pump Inhibitors - administration & dosage | Famotidine - administration & dosage | Micelles | Adult | Female | Piperazines - pharmacokinetics | Antacids - pharmacology | Protein Kinase Inhibitors - pharmacokinetics | Pyridines - administration & dosage | Drug Administration Schedule | Food-Drug Interactions | Solubility | Protein Kinase Inhibitors - administration & dosage | Rabeprazole - pharmacology | Famotidine - pharmacology | Antacids - administration & dosage | Hydrogen-Ion Concentration | Rabeprazole - administration & dosage
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