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European journal of medicinal chemistry, ISSN 0223-5234, 2015, Volume 89, pp. 743 - 816
The biological activity of Mannich bases, a structurally heterogeneous class of chemical compounds that are generated from various substrates through the introduction of an aminomethyl function... 
Aminomethylation | Drug design | Mannich bases | Structure–activity relationships | Biological activity | Structure-activity relationships | Structureeactivity relationships | CHEMISTRY, MEDICINAL | ANTIMICROBIAL ACTIVITY EVALUATION | ONE-POT SYNTHESIS | STATE ANALOG INHIBITORS | B VIRUS ACTIVITIES | ANTIMYCOBACTERIAL AGENTS ANALOGS | DOXORUBICIN-FORMALDEHYDE CONJUGATE | CORRESPONDING AZINE DERIVATIVES | REGIOSELECTIVE REACTION SYNTHESIS | MYCOBACTERIUM-TUBERCULOSIS ISOCITRATE | CYTOTOXIC ACTIVITY EVALUATION | Analgesics - pharmacology | Antioxidants - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Anticonvulsants - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Mannich Bases - chemical synthesis | Analgesics - chemical synthesis | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Drug Design | Mannich Bases - pharmacology | Antineoplastic Agents - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Antimalarials - chemical synthesis | Antifungal Agents - pharmacology | Antiviral Agents - pharmacology | Anticonvulsants - chemical synthesis | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Chemistry, Pharmaceutical | Mannich Bases - chemistry | Antimalarials - pharmacology | Anti-Bacterial Agents - chemical synthesis | Animals | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Antiviral Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Antioxidants | Antiviral agents | Enzymes | Mental illness | Bases (Chemistry)
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 08/2016, Volume 21, Issue 8, p. 1054
.... There are different available methods for the synthesis of thiazine derivatives in the literature. In this review, we discuss available methods of thiazine preparation through green synthesis methods... 
Antibacterial activity | Green synthesis | Biologically active | Anticancer agents | Thiazine | antibacterial activity | ONE-POT SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | green synthesis | 1,3-THIAZINE DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | biologically active | anticancer agents | NEUTROPHIL RESPIRATORY BURST | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGICAL-ACTIVITY | CANNABINOID RECEPTOR AGONISTS | IMMUNODEFICIENCY VIRUS FIV | MICROWAVE-ASSISTED SYNTHESIS | ALDOSE REDUCTASE | ANTIMICROBIAL ACTIVITY | thiazine | Analgesics - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Analgesics - chemical synthesis | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Thiazines - pharmacology | Antineoplastic Agents - pharmacology | Molecular Structure | Antimalarials - chemical synthesis | Antifungal Agents - pharmacology | Green Chemistry Technology | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Antineoplastic Agents - chemistry | Thiazines - chemical synthesis | Thiazines - chemistry | Antimalarials - pharmacology | Anti-Bacterial Agents - chemical synthesis | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Antimalarials - chemistry | Antiviral Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Anti-Inflammatory Agents - chemical synthesis
Journal Article
Current pharmaceutical design, ISSN 1381-6128, 06/2016, Volume 22, Issue 21, pp. 3265 - 3301
Background: The imidazole nucleus is inimitable and ubiquitous and it is very well known to play an important role in living organisms. Imidazole derivatives... 
Antimicrobial | Imidazoles | Synthesis | Click chemistry | Anticancer | synthesis | antimicrobial | H-3 RECEPTOR ANTAGONISTS | ONE-POT SYNTHESIS | click chemistry | anticancer | IN-VITRO | ANTIBACTERIAL ACTIVITY | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | VITRO ANTITUMOR-ACTIVITY | MICROWAVE-ASSISTED SYNTHESIS | ANTIMICROBIAL ACTIVITY | STRUCTURE-BASED DESIGN | Analgesics - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Imidazoles - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Infection - virology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Imidazoles - chemical synthesis | Imidazoles - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Antimalarials - chemical synthesis | Antifungal Agents - pharmacology | Antiviral Agents - pharmacology | Infection - drug therapy | Imidazoles - pharmacology | Infection - microbiology | Antineoplastic Agents - chemistry | Antimalarials - pharmacology | Anti-Bacterial Agents - chemical synthesis | Analgesics - chemistry | Antimalarials - chemistry | Antiviral Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Infection - parasitology
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2017, Volume 25, Issue 11, pp. 2817 - 2824
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