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Nature, ISSN 0028-0836, 08/2010, Volume 466, Issue 7309, pp. 935 - 940
Despite the success of genomics in identifying new essential bacterial genes, there is a lack of sustainable leads in antibacterial drug discovery to address... 
BREAKAGE-REUNION DOMAIN | B-PROTEIN | BAD BUGS | MECHANISM | COLI DNA GYRASE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | FUSION PROTEIN | INFECTIOUS-DISEASES-SOCIETY | CLEAVAGE | Staphylococcus aureus - enzymology | Crystallography, X-Ray | Structure-Activity Relationship | Quinolines - pharmacology | Quinolones - chemistry | Anti-Bacterial Agents - chemistry | Topoisomerase II Inhibitors | Apoenzymes - metabolism | DNA, Superhelical - chemistry | Drug Design | Binding Sites | Ciprofloxacin - metabolism | Drug Resistance | Catalytic Domain | Escherichia coli - enzymology | DNA Gyrase - chemistry | Quinolines - chemistry | Quinolones - metabolism | Models, Molecular | Anti-Bacterial Agents - metabolism | DNA - metabolism | Quinolines - metabolism | DNA Gyrase - metabolism | DNA - chemistry | Manganese - metabolism | Apoenzymes - chemistry | Ciprofloxacin - chemistry | Aspartic Acid - metabolism | Protein Conformation | Anti-Bacterial Agents - pharmacology | DNA, Superhelical - metabolism | Arginine - metabolism | DNA Cleavage | Antimitotic agents | Enzymes | Drug resistance in microorganisms | Topoisomerases | DNA | Genes | Research | Properties | Antineoplastic agents | Antibacterial agents | Staphylococcus aureus | Bacteria | Mutation | E coli | Deoxyribonucleic acid--DNA | Streptococcus infections | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7091, pp. 358 - 361
Journal Article
Science, ISSN 0036-8075, 5/2001, Volume 292, Issue 5518, pp. 897 - 902
Crystal structures of the 30S ribosomal subunit in complex with messenger RNA and cognate transfer RNA in the A site, both in the presence and absence of the... 
Messenger RNA | Hydrogen bonds | RNA | Antibiotics | Protein synthesis | Ribosomes | Crystals | Research Articles | Codons | Anticodon | Transfer RNA | P-SITE | ANGSTROM RESOLUTION | ELONGATION-FACTOR TU | ESCHERICHIA-COLI RIBOSOME | AMINOACYL-TRANSFER-RNA | PHENYLALANINE TRANSFER-RNA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | A-SITE | 70S RIBOSOME | DNA-REPLICATION | Codon - metabolism | Anticodon - metabolism | Protein Biosynthesis | Peptide Chain Elongation, Translational | RNA, Transfer, Phe - chemistry | Anticodon - chemistry | RNA, Transfer, Amino Acid-Specific - metabolism | Ribosomes - metabolism | Thermus thermophilus - metabolism | Crystallography, X-Ray | Thermus thermophilus - ultrastructure | Guanosine Triphosphate - metabolism | RNA, Messenger - metabolism | Paromomycin - pharmacology | Thermodynamics | Nucleic Acid Conformation | RNA, Transfer - chemistry | Binding Sites | RNA, Bacterial - metabolism | RNA, Ribosomal, 16S - metabolism | RNA, Transfer, Phe - metabolism | Thermus thermophilus - chemistry | RNA, Transfer - metabolism | Ribosomes - chemistry | Models, Molecular | Anti-Bacterial Agents - metabolism | Peptide Elongation Factor Tu - metabolism | RNA, Transfer, Amino Acid-Specific - chemistry | RNA, Ribosomal, 16S - chemistry | Ribosomes - ultrastructure | Codon - chemistry | Base Pairing | Hydrogen Bonding | RNA, Bacterial - chemistry | RNA, Messenger - chemistry | Anti-Bacterial Agents - pharmacology | Paromomycin - metabolism | Protein research | Usage | Polypeptides | Amino acids | Research | Molecular biology | Statistics | Ribonucleic acid--RNA | Ribonucleic acid | ribosomal subunit 30S | paromomysin | Index Medicus
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7654, pp. 299 - 304
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 8, pp. 4443 - 4451
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7481, pp. 103 - 107
Human body-surface epithelia coexist in close association with complex bacterial communities and are protected by a variety of antibacterial proteins. C-type... 
MULTIDISCIPLINARY SCIENCES | CHANNELS | ANTIMICROBIAL PEPTIDES | BACTERICIDAL LECTIN | CONFORMATION | PROMOTES | LIPID BILAYER-MEMBRANES | SOLVENT | INNATE IMMUNITY | Peptidoglycan - metabolism | Immunity, Mucosal - immunology | Humans | Intestines - chemistry | Lectins, C-Type - immunology | Porins - metabolism | Crystallography, X-Ray | Gram-Negative Bacteria - metabolism | Listeria monocytogenes - immunology | Antigens, Neoplasm - chemistry | Gram-Negative Bacteria - immunology | Porins - antagonists & inhibitors | Intestines - immunology | Lectins, C-Type - chemistry | Immunity, Mucosal - drug effects | Lectins, C-Type - metabolism | Anti-Bacterial Agents - chemistry | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Listeria monocytogenes - metabolism | Porins - chemistry | Phospholipids - metabolism | Biomarkers, Tumor - antagonists & inhibitors | Symbiosis | Microbial Viability - drug effects | Antigens, Neoplasm - immunology | Models, Molecular | Anti-Bacterial Agents - metabolism | Pancreatitis-Associated Proteins | Cryoelectron Microscopy | Gram-Negative Bacteria - drug effects | Anti-Bacterial Agents - immunology | Intestines - microbiology | Cell Membrane Permeability - drug effects | Lipopolysaccharides - pharmacology | Anti-Bacterial Agents - pharmacology | Biomarkers, Tumor - chemistry | Biomarkers, Tumor - immunology | Lectins, C-Type - antagonists & inhibitors | Listeria monocytogenes - drug effects | Biological research | Physiological aspects | Lectins | Membranes (Biology) | Health aspects | Biology, Experimental | Proteins | Membranes | Pore size | Microscopy | Listeria | Lipids | Index Medicus
Journal Article
Journal Article