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Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 329, Issue 5996, pp. 1168 - 1174
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of... 
Human sexual behavior | HIV infections | Antiinfectives | Gels | HIV | RESEARCH ARTICLES | Placebos | Experimentation | AIDS | Infections | Condoms | VAGINAL GEL | INDIVIDUALS | SOUTH-AFRICA | PROPHYLAXIS | IN-VITRO | TRANSMISSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | MALE CIRCUMCISION | RANDOMIZED CONTROLLED-TRIAL | CHALLENGES | HIV Infections - prevention & control | Anti-Infective Agents, Local - therapeutic use | Urban Population - statistics & numerical data | HIV Infections - epidemiology | Humans | Anti-Infective Agents, Local - adverse effects | Drug Resistance, Viral | Administration, Intravaginal | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Tenofovir | Young Adult | Adenine - adverse effects | HIV-1 - physiology | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Vaginal Creams, Foams, and Jellies | Rural Population - statistics & numerical data | Sexual Behavior | Adenine - analogs & derivatives | Double-Blind Method | Organophosphonates - therapeutic use | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | South Africa - epidemiology | Organophosphonates - adverse effects | Adenine - administration & dosage | Pregnancy | Organophosphonates - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Adolescent | Patient Compliance | Pregnancy Outcome | Prevention | Anti-infective agents | Research | HIV infection
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 4, pp. 792 - 800
Summary Hepatitis C virus (HCV) infected patients often take multiple co-medications to treat adverse events related to HCV therapy, or to manage other... 
Gastroenterology and Hepatology | Boceprevir | Hepatitis C virus infection | Telaprevir | Pharmacokinetics | Drug interactions | CHRONIC HEPATITIS-C | GASTROENTEROLOGY & HEPATOLOGY | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Hepatitis C, Chronic - metabolism | Antiviral Agents - pharmacokinetics | Hypnotics and Sedatives - adverse effects | Humans | Hypnotics and Sedatives - administration & dosage | Drug Interactions | Hypoglycemic Agents - administration & dosage | Drug Therapy, Combination | Immunosuppressive Agents - administration & dosage | Cardiovascular Agents - administration & dosage | Anti-Infective Agents - adverse effects | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Opiate Substitution Treatment - adverse effects | Buprenorphine - administration & dosage | Anti-Infective Agents - administration & dosage | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Antiviral Agents - adverse effects | Buprenorphine - adverse effects | Antidepressive Agents - administration & dosage | Immunosuppressive Agents - adverse effects | Methadone - administration & dosage | Methadone - adverse effects | Antidepressive Agents - adverse effects | Cardiovascular Agents - adverse effects | Hypoglycemic Agents - adverse effects | Hepatitis C virus
Journal Article
Acta Pharmacologica Sinica, ISSN 1671-4083, 05/2018, Volume 39, Issue 5, pp. 787 - 801
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal herb and health supplement... 
arctigenin | arctiin | Fructus Arctii | Arctium lappa L | pharmacokinetics | anti-inflammatory agents | clinical efficacy | CANCER-CELLS | NITRIC-OXIDE SYNTHASE | STRUCTURAL TRANSFORMATION | KAPPA-B | CHEMISTRY, MULTIDISCIPLINARY | PHENYLPROPANOID DIBENZYLBUTYROLACTONE LIGNAN | PLANT LIGNAN | SESQUITERPENE LACTONES | HUMAN INTESTINAL BACTERIUM | IN-VITRO | TRADITIONAL CHINESE MEDICINE | PHARMACOLOGY & PHARMACY | Anti-Infective Agents - pharmacology | Furans - pharmacology | Humans | Diabetic Nephropathies - drug therapy | Glucosides - pharmacokinetics | Antineoplastic Agents - administration & dosage | Lignans - pharmacology | Furans - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Lignans - therapeutic use | Pancreatic Neoplasms - drug therapy | Furans - pharmacokinetics | Neuroprotective Agents - pharmacology | Neuroprotective Agents - pharmacokinetics | Arctium | Glucosides - therapeutic use | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Neuroprotective Agents - administration & dosage | Glucosides - pharmacology | Lignans - administration & dosage | Lignans - pharmacokinetics | Animals | Anti-Infective Agents - administration & dosage | Glucosides - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Infective Agents - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Cell Line, Tumor | Furans - administration & dosage | Medicinal plants | Effectiveness | Cytokines | Liver | Oral administration | Pharmacology | Inflammation | Chemical compounds | Biological activity | Nitric-oxide synthase | Herbal medicine | Intestine | Nitric oxide | Pharmacokinetics | Review
Journal Article
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 2014, Volume 2014, Issue 5, p. CD003948
..., through selection of appropriate dressings and topical agents. Objectives To review the evidence of the effects of dressings and topical agents on quality of life, and symptoms that impact on quality of life, in people with fungating malignant wounds... 
Anti‐Infective Agents, Local | Antineoplastic Agents | Wounds | Phosphorylcholine | Dressings and topical agents | Disease Progression | Odorants | Malignant wounds | Skin disorders | Randomized Controlled Trials as Topic | Wounds and Injuries | Treatment | Local wound care | Silver Compounds | Skin Neoplasms | Child health | Skin Ulcer | Skin | Metronidazole | Biological Dressings | Medicine General & Introductory Medical Sciences | Ointments | HONEY | Wounds and Injuries [drug therapy] | Humans | SILVER | Skin Ulcer [drug therapy] | Male | CUTANEOUS METASTASES | MALIGNANT WOUNDS | Anti-Infective Agents, Local [administration & dosage] Antineoplastic Agents [administration & dosage] | TRIAL | EXPERIENCES | MEDICINE, GENERAL & INTERNAL | Metronidazole [administration & dosage] | Odors [prevention & control] | Ointments [administration & dosage] | Skin Neoplasms [drug therapy] | DOUBLE-BLIND | MILTEFOSINE | Female | Phosphorylcholine [administration & dosage; analogs & derivatives] | METRONIDAZOLE | Skin Neoplasms - drug therapy | Metronidazole - administration & dosage | Antineoplastic Agents - administration & dosage | Phosphorylcholine - analogs & derivatives | Phosphorylcholine - administration & dosage | Skin Neoplasms - complications | Silver Compounds - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Skin Ulcer - drug therapy | Wounds and Injuries - drug therapy | Ointments - administration & dosage | Odorants - prevention & control
Journal Article
Journal of investigative dermatology, ISSN 0022-202X, 2013, Volume 133, Issue 5, pp. 1231 - 1239
...) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver antimicrobial agents to treat a cutaneous pathogen... 
WATER-SOLUBLE CHITOSAN | ANTIBACTERIAL PROPERTIES | MICROSPHERES | ALPHA | ACNE-VULGARIS | RELEASE | MICROPARTICLES | NANOTECHNOLOGY | DELIVERY | DERMATOLOGY | Alginates - therapeutic use | Anti-Infective Agents - pharmacology | Humans | Hexuronic Acids - administration & dosage | Skin Diseases, Bacterial - drug therapy | Drug Delivery Systems | Feasibility Studies | Nanoparticles - therapeutic use | Chitosan - therapeutic use | Anti-Inflammatory Agents - therapeutic use | Chitosan - pharmacology | Anti-Inflammatory Agents - administration & dosage | Glucuronic Acid - administration & dosage | Keratinocytes - microbiology | Alginates - pharmacology | Benzoyl Peroxide - pharmacology | Cell Line | Benzoyl Peroxide - administration & dosage | Benzoyl Peroxide - therapeutic use | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Propionibacterium acnes - physiology | Cells, Cultured | Chitosan - administration & dosage | Acne Vulgaris - drug therapy | Anti-Infective Agents - therapeutic use | Glucuronic Acid - therapeutic use | Alginates - administration & dosage | Glucuronic Acid - pharmacology | Anti-Infective Agents - administration & dosage | Keratinocytes - drug effects | Propionibacterium acnes - ultrastructure | Keratinocytes - metabolism | Nanoparticles - administration & dosage | Propionibacterium acnes - drug effects | Administration, Topical | Hexuronic Acids - pharmacology | Hexuronic Acids - therapeutic use | Index Medicus | Acne | Antimicrobial | Inflammation | Chitosan | Nanoparticle | Skin infection
Journal Article
The Lancet infectious diseases, ISSN 1473-3099, 2013, Volume 13, Issue 1, pp. 27 - 35
Summary Background Intensified antibiotic treatment might improve the outcome of tuberculous meningitis. We assessed pharmacokinetics, safety, and survival... 
Infectious Disease | MYCOBACTERIUM-TUBERCULOSIS | ETHAMBUTOL | INFECTIOUS DISEASES | IN-VITRO | PHARMACOKINETICS | LEVOFLOXACIN | PULMONARY TUBERCULOSIS | INFECTION | DRUG-RESISTANCE | CEREBROSPINAL-FLUID | CIPROFLOXACIN | Fluoroquinolones | Aza Compounds - pharmacokinetics | Antitubercular Agents - adverse effects | Rifampin - pharmacokinetics | Antibiotics, Antitubercular - adverse effects | Follow-Up Studies | Humans | Middle Aged | Aza Compounds - adverse effects | Male | Quinolines - administration & dosage | Quinolines - pharmacokinetics | Young Adult | Drug Therapy, Combination - adverse effects | Rifampin - adverse effects | Adult | Female | Rifampin - administration & dosage | Antibiotics, Antitubercular - administration & dosage | Aza Compounds - administration & dosage | Anti-Infective Agents - adverse effects | Antibiotics, Antitubercular - pharmacokinetics | Tuberculosis, Meningeal - drug therapy | Drug Administration Schedule | Drug Therapy, Combination - methods | Anti-Infective Agents - administration & dosage | Antitubercular Agents - pharmacokinetics | Anti-Infective Agents - pharmacokinetics | Adolescent | Antitubercular Agents - administration & dosage | Tuberculosis, Meningeal - metabolism | Quinolines - adverse effects | Indonesia | Tuberculosis | Meningitis | Dosage and administration | Product development | Moxifloxacin | Universities and colleges | Rifampin | Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 2014, Volume 120, Issue 10, pp. 1453 - 1461
Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational... 
no | gastrointestinal | mucositis | guidelines | oral | stomatitis | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) | HEAD | GASTROINTESTINAL MUCOSITIS | ISOO | CELL TRANSPLANTATION | RANDOMIZED-TRIAL | ZINC SUPPLEMENTATION | NECK-CANCER | ONCOLOGY | MUCOSAL INJURY | ORAL MUCOSITIS | DOUBLE-BLIND | LEVEL LASER THERAPY | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC | Sucralfate - administration & dosage | Humans | Radiotherapy - adverse effects | Antineoplastic Agents - administration & dosage | Protective Agents - therapeutic use | Mucositis - prevention & control | Proctitis - prevention & control | Antineoplastic Agents - adverse effects | Anti-Inflammatory Agents - therapeutic use | Neoplasms - radiotherapy | Intercellular Signaling Peptides and Proteins - administration & dosage | Low-Level Light Therapy | Esophagitis - therapy | Analgesics - therapeutic use | Proctitis - therapy | Anti-Infective Agents - therapeutic use | Evidence-Based Medicine | Mucositis - therapy | Cytokines - administration & dosage | Esophagitis - etiology | Stomatitis - etiology | Mucositis - chemically induced | Oral Hygiene | Anti-Ulcer Agents - administration & dosage | Neoplasms - drug therapy | Phototherapy | Stomatitis - therapy | Proctitis - etiology | Mucositis - etiology | Stomatitis - chemically induced | Esophagitis - prevention & control | Radiation-Protective Agents - therapeutic use | Stomatitis - prevention & control | Amifostine - therapeutic use | Cryotherapy | Hyperbaric Oxygenation | Practice guidelines (Medicine) | Usage | Care and treatment | Mucositis | Analysis | Cancer | Index Medicus | Abridged Index Medicus | Review
Journal Article
Cochrane library, ISSN 1465-1858, 2017, Volume 2017, Issue 6, p. CD004679
...‐site and tunnel infections. Multiple strategies have been developed to reduce the risk of peritonitis including antibiotics, topical disinfectants to the exit site and antifungal agents... 
Anti‐Infective Agents, Local | Kidney disease | Device Removal | Injections, Intravenous | End‐stage kidney disease | Gastroenterology & hepatology | Mycoses | Infection ‐ prevention and treatment | Antibiotic Prophylaxis | Mupirocin | Vancomycin | Administration, Intranasal | Randomized Controlled Trials as Topic | Peritoneal Dialysis | Anti‐Bacterial Agents | Child health | Gastroenterology | Other bowel disorders | Antifungal Agents | Medicine General & Introductory Medical Sciences | Administration, Topical | Catheter‐Related Infections | Peritonitis | CAPD PATIENTS | CLINICAL-TRIAL | Y-CONNECTOR | Humans | Peritonitis [prevention & control] | RANDOMIZED CONTROLLED-TRIAL | CATHETER-RELATED INFECTIONS | INTRANASAL MUPIROCIN | Anti-Bacterial Agents [therapeutic use] | Peritoneal Dialysis [adverse effects] | Mupirocin [therapeutic use] | MEDICINE, GENERAL & INTERNAL | EXIT-SITE INFECTION | MUPIROCIN PROPHYLAXIS | STAPHYLOCOCCUS-AUREUS | ANTIBACTERIAL HONEY | Mycoses - prevention & control | Anti-Infective Agents, Local - therapeutic use | Vancomycin - administration & dosage | Device Removal - adverse effects | Mupirocin - administration & dosage | Peritonitis - epidemiology | Mupirocin - therapeutic use | Catheter-Related Infections - prevention & control | Antifungal Agents - therapeutic use | Anti-Bacterial Agents - therapeutic use | Peritoneal Dialysis - adverse effects | Anti-Infective Agents, Local - administration & dosage | Vancomycin - therapeutic use | Peritonitis - prevention & control | Anti-Bacterial Agents - administration & dosage | Antifungal Agents - administration & dosage | Catheter-Related Infections - epidemiology
Journal Article