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Journal of controlled release, ISSN 0168-3659, 2015, Volume 207, pp. 18 - 30
Exosomes are naturally occurring nanosized vesicles that have attracted considerable attention as drug delivery vehicles in the past few years. Exosomes are... 
Oxidative stress | Neuroinflammation | Parkinson's disease | Catalase | Exosomes | Blood–brain barrier | Blood-brain barrier | ALZHEIMERS-DISEASE | REPEATED INJECTIONS | MACROPHAGE DELIVERY | MEDIATED TRANSFER | BLOOD-BRAIN-BARRIER | BIOLOGICAL BARRIERS | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | PEGYLATED LIPOSOMES | PHARMACOLOGY & PHARMACY | SUPEROXIDE-DISMUTASE | Antioxidants - chemistry | Antioxidants - metabolism | Oxidopamine | Anti-Inflammatory Agents - metabolism | PC12 Cells | Neuroprotective Agents - metabolism | Drug Carriers | Brain - metabolism | Nanoparticles | Parkinsonian Disorders - metabolism | Parkinsonian Disorders - drug therapy | Antiparkinson Agents - chemistry | Anti-Inflammatory Agents - administration & dosage | Female | Neurons - metabolism | Neuroprotective Agents - administration & dosage | Nanomedicine | Disease Models, Animal | Neuroprotective Agents - chemistry | Mice, Inbred C57BL | Solubility | Rats | Technology, Pharmaceutical - methods | Parkinsonian Disorders - chemically induced | Administration, Intranasal | Chemistry, Pharmaceutical | Brain - drug effects | Catalase - metabolism | Catalase - administration & dosage | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - administration & dosage | RAW 264.7 Cells | Antiparkinson Agents - administration & dosage | Mice | Kinetics | Oxidative Stress - drug effects | Antiparkinson Agents - metabolism | Catalase - chemistry | Drugs | Drug delivery systems | Proteases | Analysis | Antiparkinsonian agents | Vehicles | blood-brain barrier | neuroinflammation | exosomes | catalase | oxidative stress | Parkinson’s disease
Journal Article
Journal Article
Acta Pharmacologica Sinica, ISSN 1671-4083, 05/2018, Volume 39, Issue 5, pp. 787 - 801
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal herb and health supplement... 
arctigenin | arctiin | Fructus Arctii | Arctium lappa L | pharmacokinetics | anti-inflammatory agents | clinical efficacy | CANCER-CELLS | NITRIC-OXIDE SYNTHASE | STRUCTURAL TRANSFORMATION | KAPPA-B | CHEMISTRY, MULTIDISCIPLINARY | PHENYLPROPANOID DIBENZYLBUTYROLACTONE LIGNAN | PLANT LIGNAN | SESQUITERPENE LACTONES | HUMAN INTESTINAL BACTERIUM | IN-VITRO | TRADITIONAL CHINESE MEDICINE | PHARMACOLOGY & PHARMACY | Anti-Infective Agents - pharmacology | Furans - pharmacology | Humans | Diabetic Nephropathies - drug therapy | Glucosides - pharmacokinetics | Antineoplastic Agents - administration & dosage | Lignans - pharmacology | Furans - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Lignans - therapeutic use | Pancreatic Neoplasms - drug therapy | Furans - pharmacokinetics | Neuroprotective Agents - pharmacology | Neuroprotective Agents - pharmacokinetics | Arctium | Glucosides - therapeutic use | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Neuroprotective Agents - administration & dosage | Glucosides - pharmacology | Lignans - administration & dosage | Lignans - pharmacokinetics | Animals | Anti-Infective Agents - administration & dosage | Glucosides - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Infective Agents - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Cell Line, Tumor | Furans - administration & dosage | Medicinal plants | Effectiveness | Cytokines | Liver | Oral administration | Pharmacology | Inflammation | Chemical compounds | Biological activity | Nitric-oxide synthase | Herbal medicine | Intestine | Nitric oxide | Pharmacokinetics | Review
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 2014, Volume 50, Issue 80, pp. 11788 - 11805
... potential of H2S in the future. Hydrogen sulfide releasing agents (also known as H2S donors... 
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 7, pp. 1320 - 1329.e3
Background & Aims Infliximab, a tumor necrosis factor antagonist, is effective for treating patients with Crohn’s disease (CD) and ulcerative colitis (UC). We... 
Gastroenterology and Hepatology | Personalized Medicine | Pharmacokinetics | Therapeutic Drug Monitoring | Monoclonal Antibody | DOSE INTENSIFICATION | MAINTENANCE | THERAPY | CROHNS-DISEASE | EFFICACY | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | WITHDRAWAL | Drug Costs | Recurrence | Crohn Disease - economics | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Gastrointestinal Agents - administration & dosage | Male | Colitis, Ulcerative - immunology | Gastrointestinal Agents - economics | Antibodies, Monoclonal - blood | Drug Dosage Calculations | Anti-Inflammatory Agents - adverse effects | Infliximab | Crohn Disease - diagnosis | Adult | Anti-Inflammatory Agents - administration & dosage | Anti-Inflammatory Agents - pharmacokinetics | Female | Colitis, Ulcerative - drug therapy | Gastrointestinal Agents - pharmacokinetics | Anti-Inflammatory Agents - economics | Tertiary Care Centers | Antibodies, Monoclonal - pharmacokinetics | Treatment Outcome | Colitis, Ulcerative - blood | Crohn Disease - immunology | Remission Induction | Anti-Inflammatory Agents - blood | Algorithms | Belgium | Colitis, Ulcerative - diagnosis | Antibodies, Monoclonal - administration & dosage | Cost-Benefit Analysis | Crohn Disease - blood | Crohn Disease - drug therapy | Gastrointestinal Agents - adverse effects | Gastrointestinal Agents - blood | Colitis, Ulcerative - economics | Drug Monitoring | Antibodies, Monoclonal - economics | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Care and treatment | Continuing medical education | Consulting services | Ulcerative colitis
Journal Article
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 2014, Volume 2014, Issue 10, p. CD006618
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5‐aminosalicylates are the most commonly used therapies.... 
Colitis, Ulcerative | Mesalamine | Immunosuppressive Agents | Administration, Oral | Gastroenterology & hepatology | Induction Chemotherapy | Ulcerative colitis: induction of remission | Randomized Controlled Trials as Topic | Inflammatory bowel disease | Anti‐Inflammatory Agents | Methotrexate | Medicine General & Introductory Medical Sciences | ULCERATIVE COLITIS ‐ INDUCTION OF REMISSION | Mercaptopurine | Immunosuppressive Agents [administration & dosage; adverse effects] | 6-Mercaptopurine [administration & dosage] | Methotrexate [administration & dosage; adverse effects] | CROHNS-DISEASE | EFFICACY | Induction Chemotherapy [methods] | Humans | AZATHIOPRINE | NATIONWIDE RETROSPECTIVE COHORT | RANDOMIZED CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | INFLAMMATORY-BOWEL-DISEASE | THERAPY | Anti-Inflammatory Agents [administration & dosage; adverse effects] | PHARMACOKINETICS | Colitis, Ulcerative [drug therapy] | ORAL METHOTREXATE | Mesalamine [administration & dosage] | INFLIXIMAB | Induction Chemotherapy - methods | Mercaptopurine - administration & dosage | Methotrexate - adverse effects | Anti-Inflammatory Agents - adverse effects | Anti-Inflammatory Agents - administration & dosage | Immunosuppressive Agents - adverse effects | Methotrexate - administration & dosage | Colitis, Ulcerative - drug therapy | Immunosuppressive Agents - administration & dosage | Mesalamine - administration & dosage
Journal Article
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 02/2018, Volume 2019, Issue 4, p. CD004121
...‐inflammatory agents (NSAIDs), including cyclooxygenase‐2 (COX‐2) inhibitors, to induce regression and prevent the progression of CIN... 
Uterine Cervical Neoplasms | Administration, Oral | Anti‐Inflammatory Agents, Non‐Steroidal | CANCER OF THE UTERINE CERVIX | Induction Chemotherapy | Celecoxib | Cervix | Disease Progression | Lactones | Randomized Controlled Trials as Topic | Gynaecology | Cyclooxygenase 2 Inhibitors | Sulfonamides | Gynaecological | Placebos | Medicine General & Introductory Medical Sciences | Cervical Intraepithelial Neoplasia | Sulfones | Strategies and implementation for pre‐malignant changes | Cancer | COX-2 | Sulfones [administration & dosage; therapeutic use] | Humans | Sulfonamides [administration & dosage; therapeutic use] | COLON-CANCER | MEDICINE, GENERAL & INTERNAL | PHASE-II TRIAL | CHEMOPREVENTIVE ACTIVITY | TRANSITIONAL-CELL CARCINOMA | Pyrazoles [administration & dosage; therapeutic use] | Female | Lactones [administration & dosage; therapeutic use] | INHIBITOR | UP-REGULATION | Uterine Cervical Neoplasms [drug therapy] | Induction Chemotherapy [methods] | DOUBLE-BLIND | Cyclooxygenase 2 Inhibitors [administration & dosage; therapeutic use] | CYCLOOXYGENASE-2 EXPRESSION | Anti-Inflammatory Agents, Non-Steroidal [administration & dosage; therapeutic use] | Cervical Intraepithelial Neoplasia [drug therapy] | Sulfones - therapeutic use | Cervical Intraepithelial Neoplasia - pathology | Cyclooxygenase 2 Inhibitors - administration & dosage | Induction Chemotherapy - methods | Cervical Intraepithelial Neoplasia - drug therapy | Uterine Cervical Neoplasms - drug therapy | Uterine Cervical Neoplasms - pathology | Celecoxib - therapeutic use | Lactones - therapeutic use | Placebos - therapeutic use | Sulfonamides - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Lactones - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Cyclooxygenase 2 Inhibitors - therapeutic use | Adult | Sulfonamides - administration & dosage | Sulfones - administration & dosage
Journal Article
Food and Function, ISSN 2042-6496, 12/2014, Volume 6, Issue 1, pp. 296 - 33
Beneficial effects of green tea ( Camellia sinensis , Theaceae) extracts against obesity have been reported; however, the anti-obesity ability of the major... 
SUPPLEMENTATION |