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1974, Medicinal chemistry : a series of monographs, ISBN 9780126239010, Volume 13, 2 v.
Book
2011, Annals of the New York Academy of Sciences, ISBN 1573318140, Volume 1215, 170
Book
Nature, ISSN 0028-0836, 12/2010, Volume 468, Issue 7327, pp. 1119 - 1123
Interaction of pathogens with cells of the immune system results in activation of inflammatory gene expression. This response, although vital for immune... 
MACHINES | BINDING MODULES | CHROMATIN | MULTIDISCIPLINARY SCIENCES | COMPLEXES | GENE-EXPRESSION | BROMODOMAIN PROTEIN BRD4 | TRANSCRIPTIONAL ELONGATION | P-TEFB | Sepsis - prevention & control | Salmonella Infections - immunology | Shock, Septic - prevention & control | Salmonella Infections - physiopathology | Salmonella typhimurium | Heterocyclic Compounds, 4 or More Rings - pharmacology | Sepsis - drug therapy | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Inflammation - drug therapy | Shock, Septic - drug therapy | Anti-Inflammatory Agents - therapeutic use | Hydroxamic Acids - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Protein Structure, Tertiary | Salmonella Infections - drug therapy | Genome-Wide Association Study | Epigenomics | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Heterocyclic Compounds, 4 or More Rings - chemistry | Kaplan-Meier Estimate | Models, Molecular | Salmonella Infections - prevention & control | Benzodiazepines | Gene Expression Regulation - drug effects | Acetylation - drug effects | Animals | Anti-Inflammatory Agents - chemistry | Lipopolysaccharides - pharmacology | Histone Deacetylase Inhibitors - pharmacology | Macrophages - drug effects | Inflammation - prevention & control | Mice | Proteins | Pathology | Eukaryotes | Chromatin | Immunology | Pharmacology | Gene expression | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 13, pp. 5995 - 5999
Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and... 
T lymphocytes | Antioxidants | Oxidative stress | RNA | Chronic hepatitis | Antivirals | Viruses | Infections | Inhibitory concentration 50 | Hepacivirus | Hepatoprotection | Milk thistle | Hepatitis C | Liver disease | Botanical medicine | OXIDATIVE STRESS | PLUS RIBAVIRIN | ACTIVATION | liver disease | hepatitis C | MULTIDISCIPLINARY SCIENCES | LIVER-DISEASE | CORE PROTEIN | IN-VITRO | HEPATITIS-C VIRUS | MARIANUM MILK THISTLE | INFECTION | botanical medicine | NF-KAPPA-B | milk thistle | hepatoprotection | Flavonolignans - isolation & purification | Antioxidants - chemistry | Hepatitis C - drug therapy | Immunologic Factors - isolation & purification | Humans | NF-kappa B - metabolism | Protective Agents - chemistry | Silymarin - chemistry | Liver - drug effects | Antiviral Agents - chemistry | Protective Agents - pharmacology | T-Lymphocytes - drug effects | Anti-Inflammatory Agents - isolation & purification | Silymarin - pharmacology | Drug Evaluation, Preclinical | Hepatitis C - prevention & control | Antiviral Agents - pharmacology | Immunologic Factors - chemistry | Anti-Inflammatory Agents - pharmacology | Flavonolignans - pharmacology | Liver - metabolism | Protective Agents - isolation & purification | Antioxidants - pharmacology | Anti-Inflammatory Agents - chemistry | Antioxidants - isolation & purification | Cell Line, Tumor | T-Lymphocytes - immunology | Liver - cytology | Flavonolignans - chemistry | Oxidative Stress - drug effects | Antiviral Agents - isolation & purification | Immunologic Factors - pharmacology | Medicinal plants | Care and treatment | Usage | Flavones | Bioflavonoids | Development and progression | Research | Properties | Flavonoids | Medicine, Botanic | Medicine, Herbal | Health aspects | Hepatitis | T cell receptors | Effects | Deoxyribonucleic acid--DNA | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 22, pp. 9262 - 9267
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 08/2016, Volume 119, Issue 5, pp. 652 - 665
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2007, Volume 15, Issue 17, pp. 5738 - 5751
A novel series of 1-acylthiosemicarbazides, 1,2,4-triazole-5-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones was synthesized... 
Thiosemicarbazide | Triazol | Hydrazone | Analgesic-anti-inflammatory and antimicrobial activities | Thiadiazole | 2-Benzoxazolinone | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | hydrazone | 2-benzoxazolinone | CYCLOOXYGENASE | analgesic-anti-inflammatory and antimicrobial | ACYLARYLHYDRAZONES | triazol | ACID-DERIVATIVES | IN-VITRO | thiosemicarbazide | ANTITUBERCULOSIS ACTIVITY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | activities | thiadiazole | NITRIC-OXIDE | 2-BENZOXAZOLINONE DERIVATIVES | AGENTS | ANTIFUNGAL | Analgesics - pharmacology | Triazoles - chemistry | Crystallography, X-Ray | Structure-Activity Relationship | Analgesics - chemical synthesis | Thiadiazoles - chemistry | Thiadiazoles - therapeutic use | Anti-Bacterial Agents - chemistry | Hydrazones - therapeutic use | Semicarbazides - pharmacology | Semicarbazides - chemistry | Anti-Inflammatory Agents - therapeutic use | Triazoles - chemical synthesis | Molecular Structure | Thiadiazoles - pharmacology | Triazoles - therapeutic use | Microbial Viability - drug effects | Anti-Inflammatory Agents - pharmacology | Models, Molecular | Edema - drug therapy | Hydrazones - chemical synthesis | Semicarbazides - therapeutic use | Hydrazones - chemistry | Hydrazones - pharmacology | Anti-Bacterial Agents - chemical synthesis | Semicarbazides - chemical synthesis | Triazoles - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Benzoxazoles - chemistry | Thiadiazoles - chemical synthesis | Analgesics - chemistry | Hindlimb - drug effects | Anti-Bacterial Agents - pharmacology | Anti-Inflammatory Agents - chemical synthesis | Mice | Methylation | Edema - pathology | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2013, Volume 70, pp. 846 - 856
A series of new -[(benzo)thiazol-2-yl]-2/3-[3,4-dihydroisoquinolin-2(1 )-yl]ethan/propanamide derivatives was synthesized and characterized by H, C NMR and IR... 
Psychotropic activity | Cytotoxicity | Anti-inflammatory activity | Antimicrobial activity | Thiazole | Tetrahydroisoquinoline | NIH 3T3 Cells | Hypoxia - drug therapy | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Seizures - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Crystallography, X-Ray | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Psychomotor Agitation - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Isoquinolines - chemistry | Benzothiazoles - chemical synthesis | Isoquinolines - pharmacology | Anti-Bacterial Agents - chemistry | Psychotropic Drugs - pharmacology | Antineoplastic Agents - pharmacology | Molecular Structure | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Anesthesia, Inhalation | Antifungal Agents - pharmacology | Fungi - drug effects | Benzothiazoles - pharmacology | Models, Molecular | Edema - drug therapy | Psychotropic Drugs - chemistry | Antineoplastic Agents - chemistry | Chemistry, Physical | Anti-Bacterial Agents - chemical synthesis | Animals | Isoquinolines - chemical synthesis | Benzothiazoles - chemistry | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Mice | Carrageenan | Edema - chemically induced | Drug Screening Assays, Antitumor | Psychotropic Drugs - chemical synthesis | Index Medicus
Journal Article