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1. Full Text Flavonoids as prospective compounds for anti-cancer therapy
by Ravishankar, Divyashree and Rajora, Amit Kumar and Greco, Francesca and Osborn, Helen. M.I
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 2013, Volume 45, Issue 12, pp. 2821 - 2831
Flavonoids, which are polyphenolic compounds, are a class of plant secondary metabolites possessing a broad spectrum of pharmacological activity including... 
Polyphenolics | Flavonoids | Anti-cancer activity
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2. Cell targeting in anti-cancer gene therapy
by Lila, Mohd Azmi Mohd and Siew, John Shia Kwong and Zakaria, Hayati and Saad, Suria Mohd and Ni, Lim Shen and Abdullah, Jafri Malin
Cell targeting in anti-cancer gene therapy, 12/2004
Gene therapy is a promising approach towards cancer treatment. The main aim of the therapy is to destroy cancer cells, usually by apoptotic mechanisms, and... 
Gene therapy, anti-cancer, cell targeting, apoptosis
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3. Off-label use of anti-cancer drugs in India: To be or not to be
by Gota, Vikram and Patial, Pankaj
05/2011
Background: Administering drugs outside the terms of their official labeling is called off-label use. In the West, oncologists often use drugs off-label, which... 
Anti-cancer drugs | survey | off-label
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4. Full Text Enhanced anticancer effects of a methylation inhibitor by inhibiting a novel DNMT1 target, CEP 131, in cervical cancer
by Dong Hyun Kim and and Hye-min Kim and Pham Thi Thu Huong and Ho-jin Han and Joonsung Hwang and Hyunjoo Cha-molstad and Kyung Ho Lee and In-ja Ryoo and Kyoon Eon Kim and Yang Hoon Huh and Jong Seog Ahn and Yong Tae Kwon and Nak-kyun Soung and Bo Yeon Kim
BMB Reports, ISSN 1976-6696, 2019, Volume 52, Issue 5, p. 342
Methylation is a primary epigenetic mechanism regulating gene expression. 5-aza-2'-deoxycytidine is an FDA-approved drug prescribed for treatment of cancer by... 
DNMT1 | CEP131 | Anti-cancer | Centrosome
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5. Full Text Synthesis and evaluation of 2′H-spiro[cyclohexane-1,3′-imidazo[1,5-a]pyridine]-1′,5′-dione derivatives as Mnk inhibitors
by Abdelaziz, Ahmed M and Basnet, Sunita K.C and Islam, Saiful and Li, Manjun and Tadesse, Solomon and Albrecht, Hugo and Gerber, Cobus and Yu, Mingfeng and Wang, Shudong
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2019, Volume 29, Issue 18, pp. 2650 - 2654
Post-translational modulation of eIF4E through phosphorylation by Mnks is highly integral to the pathogenesis of different cancers. Therefore, inhibition of... 
eFT508 | eIF4E | Inhibitor | Mnk | Anti-cancer
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6. Anticancer Activities of Nigella sativa (Black Cumin)
by Khan, Md. Asaduzzaman and Chen, Han-chun and Tania, Mousumi and Zhang, Dian-zheng
01/2014
Nigella sativa has been used as traditional medicine for centuries. The crude oil and thymoquinone (TQ) extracted from its seeds and oil are effective against... 
Nigella sativa | Thymoquinone | Anti-cancer mechanism | Traditional medicine | Antioxidant
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7. Full Text Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2 H -chromene derivatives as potent anti-breast cancer agents
by Rahmani-Nezhad, Samira and Safavi, Maliheh and Pordeli, Mahboobeh and Ardestani, Sussan Kabudanian and Khosravani, Leila and Pourshojaei, Yaghoub and Mahdavi, Mohammad and Emami, Saeed and Foroumadi, Alireza and Shafiee, Abbas
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2014, Volume 86, pp. 562 - 569
A series of 2-aryl-3-nitro-2H-chromenes 4a-u were designed as hybrid analogs of flavanone, β-nitrostyrene and nitrovinylstilbene scaffolds. They were... 
Anti-cancer agents | Caspase-3 | 2H-chromene | β-Nitrostyrene | Apoptosis
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8. Full Text Kinetic Analysis of Nano-structures Formed by Enzyme-Instructed Intracellular Assemblies against Cancer Cells
by Li, Jie and Bullara, Domenico and Du, Xuewen and He, Hongjian and Sofou, Stavroula and Kevrekidis, Ioannis G and Epstein, Irving R and Xu, Bing
ACS nano, ISSN 1936-0851, 4/2018, Volume 12, Issue 4, pp. 3804 - 3815
Recent studies have demonstrated that enzyme-instructed self-assembly (EISA) in extra- or intracellular environments can serve as a multistep process for... 
enzyme | self-assembly | stereochemistry | nanostructure | anti-cancer
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9. Full Text Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg 3 in human colon cancer cell lines
by Lee, Seo Young and Kim, Geun Tae and Roh, Si Hun and Song, Jin-Su and Kim, Hie-Joon and Hong, Soon-Sun and Kwon, Sung Won and Park, Jeong Hill
Bioscience, Biotechnology and Biochemistry, ISSN 0916-8451, 2009, Volume 73, Issue 4, pp. 811 - 816
Colon cancer | Anti-cancer activity | Proteomics | Ginsenoside
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10. Full Text Synthesis and anti-gastric cancer activity evaluation of novel triazole nucleobase analogues containing steroidal/coumarin/quinoline moieties
by Zhao, Jian-Wei and Wu, Zeng-Hui and Guo, Jia-Wen and Huang, Li-Hua and Huang, Ming-Jie and You, Ya-Zhen and Liu, Hong-Min
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 181, pp. 111520 - 111520
A series of novel triazole nucleobase analogues containing steroidal/coumarin/quinoline moieties have been synthesized based on copper-catalyzed azide-alkyne... 
Hybrid | 1,2,3-Triazole | Nucleobase | Migration | Invasion | Anti-cancer activity | Index Medicus
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11. Full Text New 3-tetrazolyl-β-carbolines and β-carboline-3-carboxylates with anti-cancer activity
by Panice, Manuela Ribeiro and Lopes, Susana M.M and Figueiredo, Mariana Cecchetto and Goes Ruiz, Ana Lucia T and Foglio, Mary Ann and Nazari Formagio, Anelise S and Sarragiotto, Maria Helena and Pinho e Melo, Teresa M.V.D
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2019, Volume 179, pp. 123 - 132
The synthesis and anticancer activity of novel β-carbolines is reported. New tryptamines have been prepared via hetero-Diels-Alder reaction of nitrosoalkenes... 
Cycloaddition | Tetrazoles | Anti-cancer agents | β-Carbolines | Nitrosoalkenes | Index Medicus
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12. Full Text Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives
Bioorganic & medicinal chemistry letters, 08/2019, pp. 126615 - 126615
Index Medicus
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13. Full Text Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling
by Xing, Yue-Xiao and Li, Ming-Hui and Tao, Liang and Ruan, Ling-Yu and Hong, Wei and Chen, Cheng and Zhao, Wen-Long and Xu, Han and Chen, Jian-Feng and Wang, Jun-Song
Journal of Proteome Research, ISSN 1535-3893, 05/2018, Volume 17, Issue 5, pp. 1943 - 1952
Hepatic carcinoma is one of the most common cancers in the world, with a high incidence. Emodin is an anthraquinone derived from Polygonum multiflorum Thunb,... 
metabolomics | glycolysis | ROS | HepG2 | anti-cancer | energy metabolism | emodin
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14. Research progress in anti-tumor effect of emodin
by Lin, Wan-Fu and Wang, Chen and Ling, Chang-Quan
Zhongguo Zhongyao Zazhi, ISSN 1001-5302, 10/2015, Volume 40, Issue 20, pp. 3937 - 3940
Emodin | Mechanisms | Anti-cancer
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15. Small Molecule Inhibitors of Stat3 Protein as Cancer Therapeutic Agents
by Page, Brent
11/2013
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the past few decades. Chemotherapeutic agents are now being... 
Medicinal Chemistry | Drug Design | Stat3 | 0491 | Anti-cancer | Drug Resistance | Apoptosis
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16. Mechanism of Ursolic Acid-Mediated Inhibition of Proliferation in Vascular Endothelial Glioaytoma
by Ye, Lin-Qi and Ye, Xiu-Feng and Xu, Hong
09/2013
Purpose: To investigate the effects of ursolic acid (UA) on expressions of ERK1, C-Jun, C-Myc and Cyclin D1 in Human Umbilical Vein Endothelial Cells (HUVEC),... 
Vascular endothelial cell | Glioma | Down-regulation | ERK signal pathway | Ursolic acid | Anti-cancer
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17. Full Text Two/zero-dimensional Cu(II) complexes inhibit atrial myxoma cells via apoptosis
by Tian, Yu-Ying and Xin, Zhi-Guo and Hou, Hai-Feng and Zhu, Xiao-Chun and Guo, Qian and Xiao, Qin
Journal of Molecular Structure, ISSN 0022-2860, 12/2019, Volume 1198
Two new Cu(II)-containing coordination complexes with the chemical formulae of [Cu (pydc) (H O) ] ( , pydc = 3,5-pyridinedicarboxylate) and {[Cu(H O) (H hmidc)... 
Coordination polymers | ROS | X-ray diffraction | Anti-cancer | Apoptosis
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18. Full Text Naringenin prevents doxorubicin-induced toxicity in kidney tissues by regulating the oxidative and inflammatory insult in Wistar rats
by Khan, Tajdar Husain and Ganaie, Majid Ahmad and Alharthy, Khalid Mofleh and Madkhali, Hassan and Jan, Basit Latief and Sheikh, Ishfaq Ahmad
Archives of Physiology and Biochemistry, ISSN 1381-3455, 2018, pp. 1 - 8
This study is undertaken to investigate the effects of naringenin on doxorubicin- (Dox) induced nephrotoxicity in Wistar rats. Dox 10 mg/kg body weight was... 
naringenin | doxorubicin and nephrotoxicity | Anti-cancer
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19. Full Text Ruthenium arene complexes with mono-carbonyl analogues of curcumin as pendant or bridging ligands: Synthesis, anti-cancer activity and interaction with quadruplex DNA
by Bi, Jiaming and Pay, Tianle and Wong, Zhen Xuan and Khong, Yan Yi and Kueh, Ming Xuan and Ng, Kai Jie and Lee, Peter P.F and Tan, Yong Leng Kelvin
Polyhedron, ISSN 0277-5387, 10/2019, Volume 171, pp. 396 - 402
Ruthenium arene complexes containing mono-carbonyl analogues of curcumin (MAC) functioning as pendant or bridging ligands displayed anti-proliferative activity... 
Quadruplex DNA | Intercalative binding | Ruthenium | Anti-cancer | Curcumin analogue
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20. Full Text Macrophages: The road less traveled, changing anti-cancer therapy
by Guerriero, Jennifer L
Trends in molecular medicine, ISSN 1471-4914, 5/2018, Volume 24, Issue 5, pp. 472 - 489
Macrophages are present in all vertebrate tissues and have emerged as multifarious cells with complex roles in development, tissue homeostasis and disease.... 
Tumor associated macrophages | Tumor microenvironment | Novel anti-cancer therapy | CSF-1R
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