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International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 2013, Volume 45, Issue 12, pp. 2821 - 2831
Flavonoids, which are polyphenolic compounds, are a class of plant secondary metabolites possessing a broad spectrum of pharmacological activity including... 
Polyphenolics | Flavonoids | Anti-cancer activity
Journal Article
Cell targeting in anti-cancer gene therapy, 12/2004
Gene therapy is a promising approach towards cancer treatment. The main aim of the therapy is to destroy cancer cells, usually by apoptotic mechanisms, and... 
Gene therapy, anti-cancer, cell targeting, apoptosis
Journal
05/2011
Background: Administering drugs outside the terms of their official labeling is called off-label use. In the West, oncologists often use drugs off-label, which... 
Anti-cancer drugs | survey | off-label
Web Resource
BMB Reports, ISSN 1976-6696, 2019, Volume 52, Issue 5, p. 342
Methylation is a primary epigenetic mechanism regulating gene expression. 5-aza-2'-deoxycytidine is an FDA-approved drug prescribed for treatment of cancer by... 
DNMT1 | CEP131 | Anti-cancer | Centrosome
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2019, Volume 29, Issue 18, pp. 2650 - 2654
Post-translational modulation of eIF4E through phosphorylation by Mnks is highly integral to the pathogenesis of different cancers. Therefore, inhibition of... 
eFT508 | eIF4E | Inhibitor | Mnk | Anti-cancer
Journal Article
01/2014
Nigella sativa has been used as traditional medicine for centuries. The crude oil and thymoquinone (TQ) extracted from its seeds and oil are effective against... 
Nigella sativa | Thymoquinone | Anti-cancer mechanism | Traditional medicine | Antioxidant
Web Resource
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2014, Volume 86, pp. 562 - 569
A series of 2-aryl-3-nitro-2H-chromenes 4a-u were designed as hybrid analogs of flavanone, β-nitrostyrene and nitrovinylstilbene scaffolds. They were... 
Anti-cancer agents | Caspase-3 | 2H-chromene | β-Nitrostyrene | Apoptosis
Journal Article
ACS nano, ISSN 1936-0851, 4/2018, Volume 12, Issue 4, pp. 3804 - 3815
Recent studies have demonstrated that enzyme-instructed self-assembly (EISA) in extra- or intracellular environments can serve as a multistep process for... 
enzyme | self-assembly | stereochemistry | nanostructure | anti-cancer
Journal Article
Bioscience, Biotechnology and Biochemistry, ISSN 0916-8451, 2009, Volume 73, Issue 4, pp. 811 - 816
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 181, pp. 111520 - 111520
A series of novel triazole nucleobase analogues containing steroidal/coumarin/quinoline moieties have been synthesized based on copper-catalyzed azide-alkyne... 
Hybrid | 1,2,3-Triazole | Nucleobase | Migration | Invasion | Anti-cancer activity | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2019, Volume 179, pp. 123 - 132
The synthesis and anticancer activity of novel β-carbolines is reported. New tryptamines have been prepared via hetero-Diels-Alder reaction of nitrosoalkenes... 
Cycloaddition | Tetrazoles | Anti-cancer agents | β-Carbolines | Nitrosoalkenes | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, 08/2019, pp. 126615 - 126615
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 05/2018, Volume 17, Issue 5, pp. 1943 - 1952
Hepatic carcinoma is one of the most common cancers in the world, with a high incidence. Emodin is an anthraquinone derived from Polygonum multiflorum Thunb,... 
metabolomics | glycolysis | ROS | HepG2 | anti-cancer | energy metabolism | emodin
Journal Article
Zhongguo Zhongyao Zazhi, ISSN 1001-5302, 10/2015, Volume 40, Issue 20, pp. 3937 - 3940
Journal Article
11/2013
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the past few decades. Chemotherapeutic agents are now being... 
Medicinal Chemistry | Drug Design | Stat3 | 0491 | Anti-cancer | Drug Resistance | Apoptosis
Dissertation
09/2013
Purpose: To investigate the effects of ursolic acid (UA) on expressions of ERK1, C-Jun, C-Myc and Cyclin D1 in Human Umbilical Vein Endothelial Cells (HUVEC),... 
Vascular endothelial cell | Glioma | Down-regulation | ERK signal pathway | Ursolic acid | Anti-cancer
Web Resource
Journal of Molecular Structure, ISSN 0022-2860, 12/2019, Volume 1198
Two new Cu(II)-containing coordination complexes with the chemical formulae of [Cu (pydc) (H O) ] ( , pydc = 3,5-pyridinedicarboxylate) and {[Cu(H O) (H hmidc)... 
Coordination polymers | ROS | X-ray diffraction | Anti-cancer | Apoptosis
Journal Article
Archives of Physiology and Biochemistry, ISSN 1381-3455, 2018, pp. 1 - 8
This study is undertaken to investigate the effects of naringenin on doxorubicin- (Dox) induced nephrotoxicity in Wistar rats. Dox 10 mg/kg body weight was... 
naringenin | doxorubicin and nephrotoxicity | Anti-cancer
Journal Article
Polyhedron, ISSN 0277-5387, 10/2019, Volume 171, pp. 396 - 402
Ruthenium arene complexes containing mono-carbonyl analogues of curcumin (MAC) functioning as pendant or bridging ligands displayed anti-proliferative activity... 
Quadruplex DNA | Intercalative binding | Ruthenium | Anti-cancer | Curcumin analogue
Journal Article
Trends in molecular medicine, ISSN 1471-4914, 5/2018, Volume 24, Issue 5, pp. 472 - 489
Macrophages are present in all vertebrate tissues and have emerged as multifarious cells with complex roles in development, tissue homeostasis and disease.... 
Tumor associated macrophages | Tumor microenvironment | Novel anti-cancer therapy | CSF-1R
Journal Article
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