X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (156049) 156049
Newspaper Article (10337) 10337
Newsletter (9176) 9176
Magazine Article (1735) 1735
Book Chapter (492) 492
Web Resource (278) 278
Dissertation (269) 269
Trade Publication Article (171) 171
Book / eBook (165) 165
Conference Proceeding (121) 121
Transcript (82) 82
Reference (78) 78
Book Review (74) 74
Publication (55) 55
Government Document (20) 20
Report (17) 17
Streaming Video (15) 15
Journal / eJournal (11) 11
Paper (5) 5
Video Recording (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (93356) 93356
male (57513) 57513
animals (51100) 51100
female (46999) 46999
anti-inflammatory agents - therapeutic use (33088) 33088
nonsteroidal anti-inflammatory drugs (28985) 28985
adult (26794) 26794
middle aged (25535) 25535
anti-inflammatory agents, non-steroidal - therapeutic use (24902) 24902
anti-inflammatory agents - pharmacology (23788) 23788
pharmacology & pharmacy (23592) 23592
inflammation (22953) 22953
anti-inflammatory drugs (22620) 22620
rats (20220) 20220
mice (20214) 20214
aged (17797) 17797
anti-inflammatory agents, non-steroidal - pharmacology (16394) 16394
anti-inflammatory agents, non-steroidal - adverse effects (14554) 14554
research (14325) 14325
anti-inflammatory agents - administration & dosage (14095) 14095
treatment outcome (13964) 13964
analysis (11905) 11905
anti-inflammatory agents, non-steroidal - administration & dosage (11747) 11747
pain (9710) 9710
dose-response relationship, drug (9215) 9215
adolescent (9115) 9115
care and treatment (9073) 9073
chemistry, medicinal (8225) 8225
immunology (8097) 8097
disease models, animal (8084) 8084
risk factors (7996) 7996
time factors (7807) 7807
expression (7705) 7705
nonsteroidal antiinflammatory drugs (7702) 7702
drug therapy (7096) 7096
health aspects (6978) 6978
inflammation - drug therapy (6971) 6971
biochemistry & molecular biology (6890) 6890
analgesics (6882) 6882
cytokines (6871) 6871
anti-inflammatory (6797) 6797
drug therapy, combination (6789) 6789
medicine, general & internal (6747) 6747
anti-inflammatory agents - adverse effects (6696) 6696
drugs (6689) 6689
child (6490) 6490
rheumatology (6401) 6401
gastroenterology & hepatology (6398) 6398
double-blind method (6371) 6371
arthritis (6201) 6201
administration, topical (6068) 6068
rats, wistar (6034) 6034
inhibition (5999) 5999
anti-inflammatory agents (5916) 5916
surgery (5781) 5781
rats, sprague-dawley (5564) 5564
aspirin (5492) 5492
therapy (5381) 5381
oxidative stress (5301) 5301
activation (5277) 5277
disease (5247) 5247
cells, cultured (5228) 5228
cancer (5071) 5071
arthritis, rheumatoid - drug therapy (5064) 5064
double-blind (4980) 4980
anti-inflammatory agents, non-steroidal - chemistry (4939) 4939
anti-inflammatory agents - chemistry (4830) 4830
nf-kappa-b (4823) 4823
aged, 80 and over (4768) 4768
apoptosis (4756) 4756
cells (4726) 4726
plant extracts - pharmacology (4723) 4723
cell line (4721) 4721
administration, oral (4702) 4702
medicine & public health (4623) 4623
antioxidants (4569) 4569
rheumatoid-arthritis (4440) 4440
corticosteroids (4430) 4430
prospective studies (4413) 4413
neurosciences (4390) 4390
in-vitro (4387) 4387
dermatology (4337) 4337
medicine (4220) 4220
macrophages (4206) 4206
cell biology (4189) 4189
studies (4152) 4152
prevention (4109) 4109
medical research (4104) 4104
young adult (4068) 4068
retrospective studies (4064) 4064
patients (4034) 4034
steroids (3986) 3986
nitric oxide (3939) 3939
ibuprofen (3927) 3927
research article (3874) 3874
risk (3846) 3846
dosage and administration (3828) 3828
follow-up studies (3761) 3761
macrophages - drug effects (3740) 3740
nf-kappa b - metabolism (3717) 3717
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (123) 123
Online Resources - Online (51) 51
Collection Dvlpm't (Acquisitions) - Closed Orders (8) 8
Collection Dvlpm't (Acquisitions) - Vendor file (7) 7
UofT at Mississauga - Stacks (5) 5
Sunnybrook Health Sciences Centre - Holland Stacks (3) 3
UTL at Downsview - May be requested (3) 3
UofT at Scarborough - Stacks (3) 3
Engineering & Comp. Sci. - Stacks (1) 1
Media Commons - Audio Visual (1) 1
Mt Sinai Hospital - Online (1) 1
Robarts - Stacks (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (164780) 164780
German (3575) 3575
French (3032) 3032
Japanese (2953) 2953
Russian (1854) 1854
Chinese (1071) 1071
Spanish (914) 914
Italian (683) 683
Polish (672) 672
Portuguese (368) 368
Dutch (264) 264
Danish (238) 238
Korean (212) 212
Czech (176) 176
Hungarian (165) 165
Swedish (160) 160
Norwegian (140) 140
Croatian (106) 106
Romanian (93) 93
Ukrainian (84) 84
Finnish (80) 80
Turkish (76) 76
Bulgarian (60) 60
Hebrew (54) 54
Slovak (54) 54
Serbian (40) 40
Lithuanian (21) 21
Arabic (8) 8
Bosnian (8) 8
Slovenian (4) 4
Greek (3) 3
Icelandic (3) 3
Persian (3) 3
Afrikaans (2) 2
Malay (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Inflammation & allergy, ISSN 1871-5281, 2006
Journal
Journal of Clinical Pharmacy and Therapeutics, ISSN 0269-4727, 04/2017, Volume 42, Issue 2, pp. 228 - 233
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 2017, Volume 139, pp. 71 - 81
.... Andrographolide was isolated as a major bioactive constituent of A. paniculata in 1951, and since 1984, andrographolide and its analogs have been scrutinized with modern drug discovery approach for anti-inflammatory properties... 
Hepatitis | NF-κB | Autoimmune | Neurodegeneration | Nrf2 | Asthma | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | CELL-CYCLE ARREST | PROTECTIVE ACTIVITY | IN-VITRO | NF-kappa B | INDUCED PULMONARY-FIBROSIS | SIGNALING PATHWAY | PHARMACOLOGY & PHARMACY | COMBINATION KAN-JANG | NF-KAPPA-B | Liver Cirrhosis - immunology | Humans | Drugs, Investigational - therapeutic use | NF-E2-Related Factor 2 - agonists | Protective Agents - chemistry | Neurodegenerative Diseases - drug therapy | Hepatitis - drug therapy | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Hepatitis - metabolism | Pneumonia - immunology | Autoimmune Diseases - metabolism | Autoimmune Diseases - drug therapy | Diterpenes - pharmacology | Chemical and Drug Induced Liver Injury - prevention & control | NF-kappa B p50 Subunit - antagonists & inhibitors | NF-kappa B p50 Subunit - metabolism | Autoimmune Diseases - prevention & control | Chemical and Drug Induced Liver Injury - immunology | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Pneumonia - metabolism | Drugs, Investigational - adverse effects | Drugs, Investigational - pharmacology | Dermatitis - immunology | Neurodegenerative Diseases - prevention & control | Protective Agents - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Protective Agents - therapeutic use | Neurodegenerative Diseases - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Drugs, Investigational - chemistry | Hepatitis - prevention & control | Drug Design | Liver Cirrhosis - metabolism | Diterpenes - chemistry | Liver Cirrhosis - drug therapy | Diterpenes - therapeutic use | Liver Cirrhosis - prevention & control | Autoimmune Diseases - immunology | Dermatitis - prevention & control | Neurodegenerative Diseases - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Pneumonia - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | NF-kappa B p50 Subunit - chemistry | Hepatitis - immunology | Diterpenes - adverse effects | Dermatitis - drug therapy | Dermatitis - metabolism | Antioxidants | Medical colleges | Lead compounds | Drug discovery | Anti-inflammatory drugs | Analysis | Index Medicus
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 09/2016, Volume 6, Issue 5, pp. 363 - 373
The kidney is a vital organ for the elimination of therapeutic drugs and their metabolites... 
Organic cations | Organic anions | Drug-drug interactions | Nephrotoxicity | Renal drug transporters | ORGANIC ANION TRANSPORTER | MULTIDRUG-RESISTANCE PROTEINS | KIDNEY PROXIMAL TUBULES | CISPLATIN-INDUCED NEPHROTOXICITY | FUNCTIONAL-CHARACTERIZATION | CLINICAL PHARMACOKINETICS | INTESTINAL P-GLYCOPROTEIN | CATION TRANSPORTER-2 | MOLECULAR-IDENTIFICATION | TISSUE DISTRIBUTION | PHARMACOLOGY & PHARMACY | NSAID, non-steroidal anti-inflammatory drugs | CHO, Chinese hamster ovary | URAT, urate transporter | P-gp, P-glycoprotein | GSH, glutathione | DDIs, drug–drug interactions | HEK, human embryonic kidney | IC50, half maximal inhibitory concentration | SNP, single-nucleotide polymorphism | Review | Cmax, maximum plasma concentration | MPP+, 1-methyl-4-phenylpyridimium | OCTN, Organic zwitterions | SLC, solute carrier | TEA, tetraethylammonium | ABC, ATP-binding cassette | AUC, area under the plasma concentration curve | MRP, multidrug resistance-associated protein | NBD, nucleotide-binding domain | Drug–drug interactions | ITC, International Transporter Consortium | OA, organic anion | OAT or Oat, organic anion transporters | OC, organic cation | ATP, adenosine triphosphate | TMD, transmembrane domain | CL, plasma clearance | FDA, U.S. Food and Drug Administration | MSD, membrane-spanning domain | MW, molecular weight | NME, new molecular entity | BBB, blood–brain barrier | cation transporters | PAH, p-aminohippurate | Ki, inhibitory constant | OATP or Oatp, organic anion-transporting peptide | fe, fraction of the absorbed dose excreted unchanged in urine | MATE, multidrug and toxin extrusion protein | CLR, renal clearance | OCT or Oct, organic cation transporter
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1763 - 1774
Background & Aims The NACHT, LRR, and pyrin domain–containing protein 3 (NLRP3) inflammasome induces inflammation in response to organ injury, but little is... 
Gastroenterology and Hepatology | Innate Immune Response | Immune Regulation | Pancreas | Mouse Model | ACTIVATION | NLRP3 INFLAMMASOME | GPR81 | AGONISTS | GENE | TLR9 | MICE | HEPATOTOXICITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | SEVERITY | Liver - pathology | Inflammasomes - metabolism | Receptors, G-Protein-Coupled - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Male | NF-kappa B - metabolism | Monocytes - immunology | Lipopolysaccharides | Liver - immunology | Liver - drug effects | RNA Interference | Interleukin-1beta - metabolism | Toll-Like Receptors - drug effects | Anti-Inflammatory Agents - administration & dosage | Toll-Like Receptors - metabolism | Cytoprotection | Disease Models, Animal | Galactosamine | Chemical and Drug Induced Liver Injury - prevention & control | Anti-Inflammatory Agents - pharmacology | Down-Regulation | Liver - metabolism | Injections, Intraperitoneal | Pancreas - pathology | Pancreas - metabolism | Pancreas - immunology | Toll-Like Receptor 4 - metabolism | Chemical and Drug Induced Liver Injury - immunology | Monocytes - drug effects | Macrophages - metabolism | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Sodium Lactate - pharmacology | beta-Arrestins | Mice | Receptors, G-Protein-Coupled - genetics | RNA, Small Interfering - metabolism | Monocytes - metabolism | Pancreatitis - prevention & control | Arrestins - metabolism | Dose-Response Relationship, Drug | Pancreatitis - genetics | Transfection | Inflammasomes - drug effects | Sodium Lactate - administration & dosage | Pancreatitis - immunology | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - etiology | Macrophages - immunology | Cell Line | Immunity, Innate - drug effects | Toll-Like Receptor 4 - drug effects | Mice, Inbred C57BL | Pancreas - drug effects | Chemical and Drug Induced Liver Injury - genetics | Pancreatitis - chemically induced | Animals | Carrier Proteins - metabolism | beta-Arrestin 2 | Inflammasomes - immunology | Macrophages - drug effects | Pancreatitis - pathology | Pancreatitis - metabolism | Ceruletide | Lactates | Gastrointestinal diseases | Inflammation
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2009, Volume 373, Issue 9678, pp. 1905 - 1917
...) expression, raised macrophage migration inhibitory factor, and increased P-glycoprotein-mediated drug efflux... 
Internal Medicine | RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | OBSTRUCTIVE PULMONARY-DISEASE | HISTONE DEACETYLASE ACTIVITY | MIGRATION INHIBITORY FACTOR | ULCERATIVE-COLITIS | REGULATORY T-CELLS | RECEPTOR-BETA | RELATIVE CORTICOSTEROID INSENSITIVITY | BLOOD MONONUCLEAR-CELLS | RESPIRATORY-DISTRESS-SYNDROME | Transcription Factor AP-1 - drug effects | Glucocorticoids - therapeutic use | Transcriptional Activation - genetics | Transcription Factor AP-1 - genetics | Humans | Macrophage Migration-Inhibitory Factors - immunology | Transcriptional Activation - drug effects | Transcription Factor AP-1 - immunology | Histone Deacetylases - immunology | Transcriptional Activation - immunology | ATP-Binding Cassette, Sub-Family B, Member 1 - drug effects | Calcineurin Inhibitors | Macrophage Migration-Inhibitory Factors - genetics | Inflammation - drug therapy | Phosphodiesterase 4 Inhibitors | Anti-Inflammatory Agents - therapeutic use | Mitogen-Activated Protein Kinases - immunology | Genetic Predisposition to Disease - genetics | NF-kappa B - antagonists & inhibitors | Histone Deacetylases - genetics | Macrophage Migration-Inhibitory Factors - drug effects | Repressor Proteins - genetics | Histone Deacetylase 2 | Drug Resistance - drug effects | Inflammation - immunology | Asthma - drug therapy | ATP-Binding Cassette, Sub-Family B, Member 1 - immunology | Drug Resistance - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Drug Resistance - immunology | Repressor Proteins - immunology | Histone Deacetylases - drug effects | Mitogen-Activated Protein Kinases - genetics | Repressor Proteins - drug effects | Mitogen-Activated Protein Kinases - drug effects | Pulmonary Disease, Chronic Obstructive - drug therapy | Corticosteroids | Dosage and administration | Inflammation | Research | Drug resistance | Drug therapy | Health aspects | Complications and side effects | Risk factors | Inflammatory bowel disease | Proteins | Respiratory distress syndrome | Asthma | Steroids
Journal Article