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1. Full Text Emerging therapeutic potential of the iridoid molecule, asperuloside: A snapshot of its underlying molecular mechanisms
by Chan, Yinghan and Ng, Sin Wi and Xin Tan, Joycelin Zhu and Gupta, Gaurav and Tambuwala, Murtaza M and Bakshi, Hamid A and Dureja, Harish and Dua, Kamal and Ishaq, Muhammad and Caruso, Vanni and Chellappan, Dinesh Kumar
Chemico-Biological Interactions, ISSN 0009-2797, 01/2020, Volume 315, p. 108911
Over the years, the attention of researchers in the field of modern drug discovery and development has become further intense on the identification of active... 
Asperuloside | Anti-bacterial | Laxative | Anti-Obesity | Anti-inflammatory | Anti-Cancer
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2. Full Text Crude microcystins extracted from Microcystis aeruginosa exert anti-obesity effects by downregulating angiogenesis and adipogenesis related signaling molecules in HUVEC and 3 T3-L1 cells
by Khan, Muhammad Imran and Shin, Jin Hyuk and Kim, Jong Deog
BMC complementary and alternative medicine, ISSN 1472-6882, 05/2019, Volume 19, Issue 1, p. 100
Obesity is a risk factor for many diseases including diabetes, cancer, arthritis, and cardiovascular diseases. Angiogenesis nourishes adipose tissues and... 
Human Umbilical Vein Endothelial Cells | Microcystins - pharmacology | Cell Survival - drug effects | Microcystis - chemistry | Adipogenesis - drug effects | Humans | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Adipocytes - drug effects | 3T3-L1 Cells | Animals | Lipogenesis - genetics | Adipocytes - metabolism | Lipogenesis - drug effects | Mice | Neovascularization, Pathologic - metabolism | Anti-Obesity Agents - pharmacology | Obesity | Complications and side effects | Cellular signal transduction | Genetic aspects | Research | Neovascularization | Gene expression | Microcystis | Diabetic retinopathy | Transcription factors | Adipose tissue | Peptides | Adipocytes | Solvent extraction | Risk factors | Proteins | Antioxidants | Angiogenesis | Cell growth | Cyanobacteria | Sterol regulatory element-binding protein | Tubes | Physiology | Inhibition | Lipogenesis | Vascular endothelial growth factor | Growth factors | NF-κB protein | Risk analysis | Cadherin | 1-Phosphatidylinositol 3-kinase | Diseases | Vascular endothelial growth factor receptors | Polymerase chain reaction | Antiangiogenics | Water quality | Cardiovascular diseases | Umbilical vein | Transcription | Lipids | Arthritis | CCAAT/enhancer-binding protein | Kinases | Product safety | Heart diseases | Microcystins | Adipogenesis | AKT1 protein | Diabetes mellitus | Algae | Health risks | Endothelial cells | Signaling | Natural products | Diabetes | Cancer | Veins & arteries
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3. Full Text Fuzhu jiangtang granules combined with metformin reduces insulin resistance in skeletal muscle of diabetic rats via PI3K/Akt signaling
by Cao, Yunsong and Sun, Wen and Xu, Guangyuan
Pharmaceutical Biology, ISSN 1388-0209, 01/2019, Volume 57, Issue 1, pp. 660 - 668
Context: Fuzhu Jiangtang Granules (FJG) are a traditional Chinese used in the treatment of diabetes mellitus. However, the antidiabetic mechanism of FJG is not... 
antihypoglycemic | antioxidant | antihypolipidemic | insulin signaling pathway | anti-obesity | Antidiabetic drugs | Chinese herbal formula | PLANT SCIENCES | PATHOGENESIS | OBESITY | GLUCOSE | PHARMACOLOGY & PHARMACY | MEDICAL LABORATORY TECHNOLOGY
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4. Full Text Anti-obesity effect of Yangkyuksanwha-tang in high-fat diet-induced obese mice
by Koh, YM and Jang, SW and Ahn, TW
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, ISSN 1472-6882, 09/2019, Volume 19, Issue 1, pp. 246 - 12
Background Yangkyuksanwha-tang (YST) is an herbal medicine based on Sasang constitutional medicine (SCM) and is widely used in Korean traditional medicine. The... 
Yangkyuksanwha-tang | MORTALITY | LEPTIN | Anti-obesity | GARCINIA-CAMBOGIA | PROTEIN | EVENTS | Sasang constitutional medicine | WEIGHT-LOSS | RISK | GARDENIA-JASMINOIDES | ADIPONECTIN | INTEGRATIVE & COMPLEMENTARY MEDICINE | High-fat diet | EXPRESSION | Obesity | Usage | Care and treatment | Messenger RNA | Medicine, Botanic | Medicine, Herbal | Genetic aspects | Research | Risk factors | Adipose tissue | Kidneys | Liver | Body weight | Oral administration | Organs | Lipids | Triglycerides | CCAAT/enhancer-binding protein | Gene expression | Density | Cholesterol | Adiponectin | High fat diet | Herbal medicine | Diet | Leptin | Alternative medicine | Toxicity testing | Mice | Food
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5. Full Text “Recent advances on support materials for lipase immobilization and applicability as biocatalysts in inhibitors screening methods”-A review
by Liu, Jia and Ma, Run-Tian and Shi, Yan-Ping
Analytica Chimica Acta, ISSN 0003-2670, 12/2019
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6. Full Text Anti-Obesity Effect of Diphlorethohydroxycarmalol Isolated from Brown Alga Ishige okamurae in High-Fat Diet-Induced Obese Mice
by Ding, Yuling and Wang, Lei and Im, SeungTae and Hwang, Ouibo and Kim, Hyun-Soo and Kang, Min-Cheol and Lee, Seung-Hong
Marine Drugs, ISSN 1660-3397, 11/2019, Volume 17, Issue 11, p. 637
Diphlorethohydroxycarmalol (DPHC) is one of the most abundant bioactive compounds in Ishige okamurae. The previous study suggested that DPHC possesses strong... 
anti-obesity effect | diphlorethohydroxycarmalol (dphc) | ishige okamurae | high-fat diet mice
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7. Full Text α-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives
by Yoshioka, Yuri and Yoshimura, Naori and Matsumura, Shinichi and Wada, Hiroto and Hoshino, Maya and Makino, Shouhei and Morimoto, Masanori
Molecules, ISSN 1420-3049, 11/2019, Volume 24, Issue 22, p. 4071
Enzymatic inhibitions of crude extracts and their constituents from Zingiberaceae against both rat intestinal α-glucosidase and porcine pancreatic lipase were... 
curcuma amada roxb | α-glucosidase inhibitor | pancreatic lipase inhibitor | diterpene | anti-obesity
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8. Full Text Black rice (Oryza sativa L.) reduces obesity and improves lipid metabolism in C57BL/6J mice fed a high-fat diet
by Liu, Dong and Ji, Yanglin and Zhao, Jiang and Wang, Huali and Guo, Yatu and Wang, Hao
Journal of Functional Foods, ISSN 1756-4646, 11/2019, p. 103605
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9. Full Text Hypoglycemic activity of extracts of Chamaecyparis obtusa var. formosana leaf in rats with hyperglycemia induced by high-fat diets and streptozotocin
by Hsu, Chia-Yun and Lin, Gong-Min and Chang, Shang-Tzen
Journal of Traditional and Complementary Medicine, ISSN 2225-4110, 11/2019
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10. Full Text Novel anti-obesity peptide (RLLPH) derived from hazelnut (Corylus heterophylla Fisch) protein hydrolysates inhibits adipogenesis in 3T3-L1 adipocytes by regulating adipogenic transcription factors and adenosine monophosphate-activated protein kinase (AMPK) activation
by Wang, Ji and Zhou, Meihan and Wu, Tong and Fang, Li and Liu, Chunlei and Min, Weihong
Journal of Bioscience and Bioengineering, ISSN 1389-1723, 10/2019
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11. Full Text Clinical Challenge: Patient With Severe Obesity BMI 46 kg/m(2)
by Srivastava, G and Apovian, CM
FRONTIERS IN ENDOCRINOLOGY, ISSN 1664-2392, 10/2019, Volume 10
Obesity causes and exacerbates many disease processes and affects every organ system. Thus it is not surprising that clinical providers are often overwhelmed... 
anti-obesity medications | bariatric surgery | MANAGEMENT | weight loss drugs | EFFICACY | LOW-FAT | ADULTS | lifestyle intervention | LOW-CARBOHYDRATE-DIET | ENDOCRINOLOGY & METABOLISM | combination therapy | DYSFUNCTION | STRESS
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12. Full Text Clinical Challenge: Patient With Severe Obesity BMI 46 kg/m2
by Srivastava, Gitanjali and Apovian, Caroline M
Frontiers in Endocrinology, ISSN 1664-2392, 10/2019, Volume 10
Obesity causes and exacerbates many disease processes and affects every organ system. Thus it is not surprising that clinical providers are often overwhelmed... 
Obesity | anti-obesity medications | combination therapy | bariatric surgery | weight loss drugs | lifestyle intervention
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13. Anti-obesity Action of Fermented Barley Extracts with Lactobacillus plantarum dy-1 and Associated MicroRNA Expression in High-fat Diet-induced Obese Rats
by Zhang, JY and Xiao, X and Dong, Y and Zhou, XH
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, ISSN 0895-3988, 10/2019, Volume 32, Issue 10, pp. 755 - 755
Objective To further explore associated effects of Lactobacillus plantarum dy-1 (LFBE) on obesity and lipid metabolism at the gene expression level, the... 
Anti-obesity | ACID | miRNAs | BETA-GLUCAN | Lactobacillus plantarum dy-1 | DOWN-REGULATION | PROLIFERATION | Microarray | CITRIFOLIA L. JUICE | Fermented barley extract | SUPPLEMENTATION | ENVIRONMENTAL SCIENCES | HEPATIC LIPID-ACCUMULATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INSULIN-RESISTANCE | LIVER | LACTOBACILLUS-PLANTARUM DY-1 | Lipid metabolism
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14. Full Text Application of screening methods for weight-loss compounds and identification of new impurities in counterfeit drugs
by Lee, Ji Hyun and Park, Han Na and Park, Seongsoo and Kim, Nam Sook and Bogonda, Ganganna and Oh, Kyungsoo and Kang, Hoil
Forensic Science International, ISSN 0379-0738, 10/2019, Volume 303, p. 109932
With the increasing prevalence of obesity, the use of counterfeit drugs for weight loss is widespread owing to their easy and rapid availability. Since... 
Screening | Anti-obesity | Impurity | HR-MS | Phenolphthalein synthesis | Counterfeit drug | ADULTERANTS | LIQUID-CHROMATOGRAPHY | MEDICINE, LEGAL | DIETARY-SUPPLEMENTS | Drugs | Obesity | Nuclear magnetic resonance--NMR | Phenolphthalein | Purification | Identification methods | Weight loss | Health risks | Thyroid gland | Body weight loss | Counterfeiting | Chromatography | Customs | Side effects | Weight control | Impurities | Thyroxine | Scientific imaging | Counterfeit | Mass spectrometry | Public health
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15. Full Text Allium hookeri Root Extract Inhibits Adipogenesis by Promoting Lipolysis in High Fat Diet-Induced Obese Mice
by Kim and Jang and Lee
Nutrients, ISSN 2072-6643, 09/2019, Volume 11, Issue 10, p. 2262
: Allium hookeri (AH) is widely consumed as a herbal medicine. It possesses biological activity against metabolic diseases. The objective of this study was to... 
Cell culture | Adipose tissue | Genes | Cytotoxicity | Lipids | Body weight loss | Adipocytes | High fat diet | Rural development | Rodents | Sterol regulatory element-binding protein | Oxidation | Lipogenesis | Sulfur | Hyperphagia | Food | Adipogenesis | Appetite | Obesity | Energy expenditure | Metabolism | Gene expression | Fatty acids | Lipolysis | Nutrition research | Diet | Food intake | Leptin | Insulin resistance | Diabetes | adipogenesis | lipolysis | Allium hookeri root | high fat diet | anti-obesity
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16. Full Text Epigallocatechin Exerts Anti‐Obesity Effect in Brown Adipose Tissue
by Kim, Hae‐Soo and Moon, Jae‐Hak and Kim, Young‐Min and Huh, Joo‐Young
Chemistry & Biodiversity, ISSN 1612-1872, 10/2019, Volume 16, Issue 10, p. n/a
Catechins in green tea are well‐known to be effective in reducing the risk of obesity. The purpose of this study was to elucidate the effects of catechins... 
(−)-epigallocatechin gallate | (−)-epigallocatechin | gallic acid | anti-obesity | BIOCHEMISTRY & MOLECULAR BIOLOGY | CAFFEINE | CATECHINS | ADIPOGENESIS | CHEMISTRY, MULTIDISCIPLINARY | (-)-epigallocatechin gallate | OBESITY | GENE | (-)-EPIGALLOCATECHIN-3-GALLATE | FAT | (-)-epigallocatechin | DIFFERENTIATION | EXPRESSION | Adipose tissues | Obesity | Green tea | Catechin | Adipose tissue | Transcription | Gallic acid | Menopause | Risk reduction | Triglycerides | Adipocytes | Metabolism | Lipase | Adiponectin | Catechins | Tea | Uncoupling protein 1 | Differentiation | Adipose tissue (brown) | Adipogenesis
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17. Full Text Dietary plants, gut microbiota, and obesity: Effects and mechanisms
by Cao, Shi-Yu and Zhao, Cai-Ning and Xu, Xiao-Yu and Tang, Guo-Yi and Corke, Harold and Gan, Ren-You and Li, Hua-Bin
Trends in Food Science & Technology, ISSN 0924-2244, 10/2019, Volume 92, pp. 194 - 204
Obesity is a leading contributor to numerous diseases, such as diabetes mellitus, cardiovascular diseases, and cancers. Therefore, seeking effective and safe... 
Gut microbiota | Spice | Obesity | Anti-Obesity | Fruit | Vegetable | HIGH-FAT-DIET | GLUCOSE-INTOLERANCE | FOOD SCIENCE & TECHNOLOGY | FECAL MICROBIOTA | HUMAN HEALTH | LIPOPOLYSACCHARIDE PRODUCTION | GREEN TEA | BODY-WEIGHT | INSULIN-RESISTANCE | WEIGHT-GAIN | ADIPOSE-TISSUE | Physiological aspects | Plants | Diabetes | Microbiota (Symbiotic organisms) | Functional foods | Barley | Plants (botany) | Soybeans | Energy metabolism | Diabetes mellitus | Clinical trials | Sorghum | Exploration | Metabolism | Biological activity | Fruits | Microbiota | Diet | Termites | Cardiovascular diseases
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18. Full Text Platycodon grandiflorum Extract Reduces High-Fat Diet-Induced Obesity Through Regulation of Adipogenesis and Lipogenesis Pathways in Mice
by Hwang, Kyung-A and Hwang, Yu-Jin and Im, Pu Reum and Hwang, Hye-Jeong and Song, Jin and Kim, Young-Jun
Journal of Medicinal Food, ISSN 1096-620X, 10/2019, Volume 22, Issue 10, pp. 993 - 999
Obesity is caused by an energy imbalance between food intake and energy expenditure, and has detrimental effects on human health. Platycodon ( Platycodon... 
Full Communications | LEPTIN | CHEMISTRY, MEDICINAL | CHOLESTEROL | EFFICACY | lipolysis center dot Platycodon grandiflorum | FOOD SCIENCE & TECHNOLOGY | WEIGHT-LOSS | RATS | NUTRITION & DIETETICS | adipogenesis | INHIBITION | anti-obesity | high-fat diet | EXPRESSION | 식품과학
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19. Full Text Evaluation of anti-adipogenic active homoisoflavonoids from Portulaca oleracea
by Lee, JI and Oh, JH and Kong, CS and Seo, Y
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, ISSN 0939-5075, 09/2019, Volume 74, Issue 9-10, pp. 265 - 273
This study was performed to isolate antiobesity components from the crude extract of Portulaca oleracea. The crude extract was partitioned into n-hexane, 85%... 
OBESITY | homoisoflavonoid | BIOCHEMISTRY & MOLECULAR BIOLOGY | anti-obesity | Portulaca oleracea | PHARMACOLOGY & PHARMACY | 3T3-L1 cell | ADIPOSE-TISSUE
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20. Full Text Efficiently Anti-Obesity Effects of Unsaturated Alginate Oligosaccharides (UAOS) in High-Fat Diet (HFD)-Fed Mice
by Li, SY and He, NN and Wang, LN
MARINE DRUGS, ISSN 1660-3397, 09/2019, Volume 17, Issue 9, p. 540
Obesity and its related complications have become one of the leading problems affecting human health. However, current anti-obesity treatments are limited by... 
anti-obesity activity | ACTIVATION | CHEMISTRY, MEDICINAL | hepatoprotective effect | RISK | anti-oxidant activity | OBESITY | unsaturated alginate oligosaccharides | METABOLISM | ANTIOXIDANT | INHIBIT ADIPOGENESIS | RESISTANCE | EXTRACTS | EXPRESSION | 3T3-L1 CELLS
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