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Biomaterials, ISSN 0142-9612, 2008, Volume 29, Issue 29, pp. 4012 - 4021
Abstract There is significant interest in recent years in developing magnetic nanoparticles (MNPs) having multifunctional characteristics with complimentary... 
Advanced Basic Science | Dentistry | Tumor | Iron oxide | Anticancer agents | Anti-proliferative effects | Imaging | VITRO | HYPERTHERMIA | anti-proliferative effects | MATERIALS SCIENCE, BIOMATERIALS | CONTRAST AGENTS | ENGINEERING, BIOMEDICAL | SURFACE MODIFICATION | ADRIAMYCIN CARDIOTOXICITY | imaging | CHEMOTHERAPY | anticancer agents | iron oxide | SUPERPARAMAGNETIC NANOPARTICLES | POLY(ETHYLENE GLYCOL) | CANCER-TREATMENT | tumor | IN-VIVO | Paclitaxel - metabolism | Nanoparticles - chemistry | Magnetic Resonance Imaging - methods | Doxorubicin - chemistry | Magnetics | Drug Carriers - chemistry | Drug Delivery Systems | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Antibiotics, Antineoplastic - chemistry | Antineoplastic Agents, Phytogenic - metabolism | Doxorubicin - metabolism | Paclitaxel - administration & dosage | Doxorubicin - administration & dosage | Drug Carriers - metabolism | Antineoplastic Agents, Phytogenic - chemistry | Materials Testing | Antibiotics, Antineoplastic - administration & dosage | Particle Size | Animals | Magnetic Resonance Imaging - instrumentation | Mice, Nude | Mice | Nanoparticles - administration & dosage | Antibiotics, Antineoplastic - metabolism | Drugs | Nanoparticles | Drug delivery systems | Magnetic resonance imaging | Nanotechnology | Vehicles | Iron-oxide
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2010, Volume 141, Issue 2, pp. 183 - 192
Chemotherapy for brain glioma has been of limited value due to the inability of transport of drug across the blood-brain barrier (BBB) and poor penetration of... 
Brain glioma-bearing rats | Dual-targeting | Blood-brain barrier | Survival | Daunorubicin liposomes modified with MAN and TF | CELLS | TRANSFERRIN-RECEPTOR | SOLID TUMORS | DRUG-DELIVERY | BARRIER | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | IN-VITRO | TRANSPORT | GROWTH | PHARMACOLOGY & PHARMACY | Capillary Permeability | Antibiotics, Antineoplastic - pharmacology | Aniline Compounds - metabolism | Brain Neoplasms - pathology | Cell Membrane Permeability | Daunorubicin - pharmacology | Male | Mannosides - chemistry | Brain Neoplasms - metabolism | Drug Carriers | Glioma - metabolism | Flow Cytometry | Antibiotics, Antineoplastic - chemistry | Biological Transport | Time Factors | Glioma - pathology | Daunorubicin - metabolism | Spheroids, Cellular | Daunorubicin - administration & dosage | Rats | Brain Neoplasms - drug therapy | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Daunorubicin - chemistry | Blood-Brain Barrier - metabolism | Antibiotics, Antineoplastic - administration & dosage | Microscopy, Confocal | Animals | Transferrin - chemistry | Cell Line, Tumor | Cell Proliferation - drug effects | Mannosides - metabolism | Mice | Aniline Compounds - chemistry | Liposomes | Antibiotics, Antineoplastic - metabolism | Transferrin - metabolism | Glioma - drug therapy | Chemotherapy | Daunorubicin | Biomimetics | Gliomas | Analysis | Brain tumors | Health aspects | Cancer
Journal Article
Biochemistry, ISSN 0006-2960, 02/2017, Volume 56, Issue 6, pp. 805 - 808
The biosynthesis of the azabicyclic ring system of the azinomycin family of antitumor agents represents the “crown jewel” of the pathway and is a complex... 
DOMAIN | NAPHTHOATE | CARZINOPHILIN | MECHANISM | POLYKETIDE SYNTHASE | THIOESTERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | THERMUS-THERMOPHILUS | SEQUENCE SELECTIVITY | Azabicyclo Compounds - pharmacology | Phosphotransferases (Carboxyl Group Acceptor) - genetics | Antibiotics, Antineoplastic - pharmacology | Substrate Specificity | Antineoplastic Agents, Alkylating - pharmacology | Phosphotransferases (Carboxyl Group Acceptor) - metabolism | Amino-Acid N-Acetyltransferase - metabolism | Azabicyclo Compounds - chemistry | Azabicyclo Compounds - metabolism | Pyrrolidines - pharmacology | Streptomyces - metabolism | Peptides - metabolism | Antibiotics, Antineoplastic - chemistry | Drug Design | Pyrrolidines - metabolism | Molecular Structure | Acetylation | Dipeptides - metabolism | Antineoplastic Agents, Alkylating - chemistry | Naphthalenes - metabolism | Naphthalenes - chemistry | Recombinant Proteins - metabolism | Biocatalysis | Peptides - chemistry | Dipeptides - pharmacology | Bacterial Proteins - genetics | Amino-Acid N-Acetyltransferase - genetics | Aldehyde Oxidoreductases - genetics | Dipeptides - chemistry | Gene Knockout Techniques | Pyrrolidines - chemistry | Acetyl Coenzyme A - metabolism | Aldehyde Oxidoreductases - metabolism | Naphthalenes - pharmacology | Peptides - pharmacology | Bacterial Proteins - metabolism | Streptomyces - enzymology | Glutamic Acid - metabolism | Mutation | Antibiotics, Antineoplastic - metabolism | Antineoplastic Agents, Alkylating - metabolism | Usage | Biosynthesis | Research | Chemical properties | Pyrrole | Antineoplastic antibiotics
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2010, Volume 31, Issue 30, pp. 7797 - 7804
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 05/2015, Volume 205, pp. 206 - 217
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2011, Volume 154, Issue 3, pp. 241 - 248
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 7/2013, Volume 72, Issue 1, pp. 127 - 138
Pharmacokinetic analyses estimate the mean concentration of drug within a given tissue as a function of time, but do not give information about the spatial... 
Medicine & Public Health | Drug distribution | Tumor microenvironment | Normal tissues | Oncology | Cancer Research | Topotecan | Pharmacology/Toxicology | Mitoxantrone | Doxorubicin | MOUSE PLASMA | SOLID TUMORS | TOPOISOMERASE-I | PENETRATION | CANCER | CHEMOTHERAPY | PHARMACOKINETICS | ONCOLOGY | BLOOD-VESSELS | ADRIAMYCIN | PHARMACOLOGY & PHARMACY | PHASE-I | Doxorubicin - blood | Neoplasms - metabolism | Topoisomerase I Inhibitors - metabolism | Liver - pathology | Kidney - blood supply | Kidney - pathology | Humans | Topotecan - metabolism | Antibiotics, Antineoplastic - blood | Coronary Vessels - metabolism | Neovascularization, Pathologic - pathology | Antineoplastic Agents - metabolism | Tissue Distribution | Kidney - metabolism | Liver - drug effects | Myocardium - metabolism | Female | Antineoplastic Agents - pharmacokinetics | Doxorubicin - metabolism | Topotecan - blood | Antibiotics, Antineoplastic - pharmacokinetics | Topoisomerase I Inhibitors - pharmacokinetics | Coronary Vessels - drug effects | Coronary Vessels - pathology | Kidney - drug effects | Mitoxantrone - metabolism | Mitoxantrone - blood | Liver - metabolism | Myocardium - pathology | Neoplasms - blood supply | Doxorubicin - pharmacokinetics | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Neovascularization, Pathologic - drug therapy | Topotecan - pharmacokinetics | Antineoplastic Agents - blood | Cell Line, Tumor | Mice | Neovascularization, Pathologic - metabolism | Mitoxantrone - pharmacokinetics | Topoisomerase I Inhibitors - blood | Antibiotics, Antineoplastic - metabolism | Neoplasms - pathology | Anthracyclines | Care and treatment | Drug wholesalers | Analysis | Fluorescence | Tumors | Cancer | Index Medicus | Antitumor agents
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Journal Article
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