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Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 21, pp. 3239 - 3246
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 16, pp. 1691 - 1699
Summary Background Preclinical data and results from non-randomised trials suggest that the multikinase inhibitor sorafenib might be an effective drug for the... 
Hematology, Oncology and Palliative Medicine | AML | ONCOLOGY | ACUTE MYELOGENOUS LEUKEMIA | BONE-MARROW | CLASSIFICATION | FLT3 MUTATIONS | CYTARABINE | STEM-CELL TRANSPLANTATION | COMBINATION | ELDERLY-PATIENTS | CHEMOTHERAPY | Niacinamide - analogs & derivatives | Recurrence | Age Factors | Cytarabine - therapeutic use | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Protein Kinase Inhibitors - adverse effects | Transplantation, Homologous | Neoadjuvant Therapy - mortality | Time Factors | Phenylurea Compounds - adverse effects | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Chemotherapy, Adjuvant | Daunorubicin - therapeutic use | Double-Blind Method | Risk Factors | Kaplan-Meier Estimate | Niacinamide - adverse effects | Proportional Hazards Models | Hematopoietic Stem Cell Transplantation | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Treatment Outcome | Disease Progression | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Antimetabolites, Antineoplastic - therapeutic use | Leukemia, Myeloid, Acute - diagnosis | Antibiotics, Antineoplastic - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoadjuvant Therapy - adverse effects | Protein Kinase Inhibitors - therapeutic use | Germany | Antimitotic agents | Clinical trials | Chemotherapy | Antineoplastic agents | Standards | Cancer | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 08/2012, Volume 120, Issue 8, pp. 1570 - 1580
Journal Article
Annals of Oncology, ISSN 0923-7534, 12/2012, Volume 23, Issue 12, pp. 3069 - 3074
Luminal breast cancer is a highly endocrine responsive disease. However, the therapeutic benefit of chemotherapy (CT) in this population is not fully... 
Neoadjuvant | Chemotherapy | Hormonotherapy | Luminal breast cancer | SURVIVAL | luminal breast cancer | neoadjuvant | SUBTYPES | GENE-EXPRESSION PROFILES | PATHOLOGICAL RESPONSE | MARKERS | ENDOCRINE THERAPY | hormonotherapy | chemotherapy | TRIAL | PREOPERATIVE CHEMOTHERAPY | MOLECULAR PORTRAITS | ONCOLOGY | PROGNOSTIC-SIGNIFICANCE | Receptors, Estrogen - metabolism | Humans | Middle Aged | Antibiotics, Antineoplastic - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Ki-67 Antigen - metabolism | Antineoplastic Agents - therapeutic use | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Receptors, Progesterone - metabolism | Taxoids - therapeutic use | Receptor, Epidermal Growth Factor - metabolism | Antineoplastic Agents - adverse effects | Antineoplastic Agents, Hormonal - therapeutic use | Adult | Female | Taxoids - adverse effects | Treatment Outcome | Breast Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Disease-Free Survival | Antibiotics, Antineoplastic - therapeutic use | Keratin-8 - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Keratin-18 - metabolism | Neoadjuvant Therapy - adverse effects | Epirubicin - therapeutic use | Aged | Antineoplastic Agents, Alkylating - adverse effects | Epirubicin - adverse effects | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 10/2010, Volume 116, Issue 17, pp. 3171 - 3179
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 38, pp. 13817 - 13821
The recent success of antibody-drug conjugates (ADCs) in the treatment of cancer has led to a revived interest in microtubuledestabilizing agents. Here, we... 
Microtubules | Drug interactions | Antineoplastics | Ligands | Dimers | Breast cancer | Molecular mechanisms of action | Crystallography | Binding sites | Crystal structure | X-ray crystallography | Microtubule-targeting agents | Drug mechanism | microtubule-targeting agents | BETA-TUBULIN | VINCA-DOMAIN | MAYTANSINE | MULTIDISCIPLINARY SCIENCES | RESOLUTION | ANTIMITOTIC AGENTS | MACROCYCLIC LACTONE ANTIBIOTICS | POTENT ANTITUMOR-ACTIVITY | BREAST-CANCER | STRUCTURAL BASIS | RHIZOXIN | drug mechanism | Tubulin Modulators - chemistry | Humans | Polyketides - chemistry | Antineoplastic Agents, Phytogenic - chemistry | Crystallography, X-Ray | Maytansine - therapeutic use | Breast Neoplasms - drug therapy | Tubulin Modulators - therapeutic use | Pyrones - chemistry | Animals | Antibiotics, Antineoplastic - chemistry | Antibiotics, Antineoplastic - therapeutic use | Macrolides - chemistry | Cattle | Maytansine - chemistry | Pyrones - therapeutic use | Female | Microtubules - chemistry | Tubulin - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Macrolides - therapeutic use | Polyketides - therapeutic use | Binding Sites | Clinical Trials, Phase I as Topic | Antimitotic agents | Pharmaceutical research | Physiological aspects | Dosage and administration | Research | Tubulins | Antineoplastic agents | Binding sites (Biochemistry) | Mutagenesis | Medical treatment | Cancer | Index Medicus | Biological Sciences
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10043, pp. 488 - 497
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2015, Volume 12, Issue 2, pp. 387 - 397
Abstract Though combination chemotherapy or antitumor nanomedicine is extensively investigated, their combining remains in infancy. Additionally, enhanced... 
Internal Medicine | Luminal A breast cancer | Tamoxifen | Doxorubicin | Penta-peptide QLPVM | Nanomedicine based combinational therapy | KU70 | MEDICINE, RESEARCH & EXPERIMENTAL | EFFICACY | SUBTYPES | NANOSCIENCE & NANOTECHNOLOGY | CELL-PENETRATING PEPTIDES | RELEASE | TUMORS | DELIVERY | NANOPARTICLES | BIOLOGY | Doxorubicin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Breast - metabolism | Polyethylene Glycols - therapeutic use | Tamoxifen - administration & dosage | Breast Neoplasms - metabolism | Antineoplastic Agents, Hormonal - therapeutic use | Doxorubicin - analogs & derivatives | Female | Breast - pathology | Nanomedicine | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Doxorubicin - administration & dosage | Antineoplastic Agents, Hormonal - administration & dosage | Ku Autoantigen - chemistry | bcl-2-Associated X Protein - metabolism | Ku Autoantigen - metabolism | Oligopeptides - metabolism | Breast Neoplasms - drug therapy | Polyethylene Glycols - administration & dosage | Antibiotics, Antineoplastic - administration & dosage | Liposomes - chemistry | Animals | Antibiotics, Antineoplastic - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast - drug effects | Breast Neoplasms - pathology | Mice, Nude | Tamoxifen - therapeutic use | Cell Line, Tumor | Liposomes - metabolism | Drug Combinations | Cell-Penetrating Peptides - metabolism | Chemotherapy | Anthracyclines | Peptides | Estrogen | Breast cancer | Drug therapy, Combination | Cancer | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2012, Volume 21, Issue 4, pp. 488 - 503
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 22, pp. 5847 - 5861