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Lancet Infectious Diseases, The, ISSN 1473-3099, 2013, Volume 13, Issue 1, pp. 27 - 35
Summary Background Intensified antibiotic treatment might improve the outcome of tuberculous meningitis. We assessed pharmacokinetics, safety, and survival... 
Infectious Disease | MYCOBACTERIUM-TUBERCULOSIS | ETHAMBUTOL | INFECTIOUS DISEASES | IN-VITRO | PHARMACOKINETICS | LEVOFLOXACIN | PULMONARY TUBERCULOSIS | INFECTION | DRUG-RESISTANCE | CEREBROSPINAL-FLUID | CIPROFLOXACIN | Fluoroquinolones | Aza Compounds - pharmacokinetics | Antitubercular Agents - adverse effects | Rifampin - pharmacokinetics | Antibiotics, Antitubercular - adverse effects | Follow-Up Studies | Humans | Middle Aged | Aza Compounds - adverse effects | Male | Quinolines - administration & dosage | Quinolines - pharmacokinetics | Young Adult | Drug Therapy, Combination - adverse effects | Rifampin - adverse effects | Adult | Female | Rifampin - administration & dosage | Antibiotics, Antitubercular - administration & dosage | Aza Compounds - administration & dosage | Anti-Infective Agents - adverse effects | Antibiotics, Antitubercular - pharmacokinetics | Tuberculosis, Meningeal - drug therapy | Drug Administration Schedule | Drug Therapy, Combination - methods | Anti-Infective Agents - administration & dosage | Antitubercular Agents - pharmacokinetics | Anti-Infective Agents - pharmacokinetics | Adolescent | Antitubercular Agents - administration & dosage | Tuberculosis, Meningeal - metabolism | Quinolines - adverse effects | Indonesia | Tuberculosis | Meningitis | Dosage and administration | Product development | Moxifloxacin | Universities and colleges | Rifampin | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2011, Volume 55, Issue 12, pp. 5485 - 5492
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 2015, Volume 191, Issue 9, pp. 1058 - 1065
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 08/2012, Volume 56, Issue 8, pp. 4331 - 4340
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 12/2003, Volume 52, Issue 6, pp. 981 - 986
Objectives: To improve the bioavailability of antitubercular drugs (ATDs) as well as to assess the feasibility of administering ATDs via the respiratory route,... 
Nanoparticles | Antitubercular drugs | Nebulization | Tuberculosis | Poly(DL-lactide-co-glycolide) | INFECTIOUS DISEASES | THERAPEUTIC EFFICACY | COMPLEX | ACID | MICROSPHERES | tuberculosis | RIFAMPIN | MICROBIOLOGY | MICROPARTICLES | poly(DL-lactide-co-glycolide) | nanoparticles | PHARMACOLOGY & PHARMACY | MICE | antitubercular drugs | nebulization | Lung - microbiology | Injections, Intravenous | Area Under Curve | Half-Life | Biological Availability | Male | Tuberculosis - microbiology | Colony Count, Microbial | Mycobacterium tuberculosis - drug effects | Drug Carriers | Microspheres | Tuberculosis - drug therapy | Chemical Phenomena | Drug Compounding | Female | Isoniazid - therapeutic use | Rifampin - therapeutic use | Lung - metabolism | Rifampin - administration & dosage | Chemical and Drug Induced Liver Injury - pathology | Polymers | Antibiotics, Antitubercular - administration & dosage | Antitubercular Agents - therapeutic use | Pyrazinamide - administration & dosage | Guinea Pigs | Lactic Acid | Polyglycolic Acid | Administration, Inhalation | Chemistry, Physical | Pyrazinamide - therapeutic use | Isoniazid - administration & dosage | Particle Size | Animals | Antibiotics, Antitubercular - therapeutic use | Aerosols | Antitubercular Agents - administration & dosage | Antitubercular Agents - toxicity | Drug Combinations | Index Medicus
Journal Article
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 02/2015, Volume 60, Issue 4, pp. 549 - 556
Journal Article
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2017, Volume 72, Issue 5, pp. 1441 - 1449
Objectives: We compared the pharmacokinetics of moxifloxacin during rifampicin co-treatment or when dosed alone in African patients with drug-susceptible... 
INFECTIOUS DISEASES | TREATMENT OUTCOMES | QUANTIFICATION | MICROBIOLOGY | OPEN-LABEL | MODEL | POLYMORPHISM | 8-METHOXYFLUOROQUINOLONE | PLASMA-CONCENTRATIONS | POPULATION PHARMACOKINETICS | MULTIDRUG-RESISTANT TUBERCULOSIS | PYRAZINAMIDE | PHARMACOLOGY & PHARMACY | Tuberculosis, Pulmonary - microbiology | Tuberculosis, Pulmonary - metabolism | Antibiotics, Antitubercular - adverse effects | Rifampin - blood | Coinfection - drug therapy | Humans | Male | Tuberculosis, Pulmonary - drug therapy | Fluoroquinolones - pharmacokinetics | Reverse Transcriptase Inhibitors - administration & dosage | Tuberculosis, Pulmonary - complications | Anti-HIV Agents - administration & dosage | Reverse Transcriptase Inhibitors - adverse effects | Rifampin - adverse effects | Drug Interactions | Adult | Anti-HIV Agents - therapeutic use | Benzoxazines - blood | Female | Rifampin - therapeutic use | Reverse Transcriptase Inhibitors - therapeutic use | Rifampin - administration & dosage | Drug Therapy, Combination | Antibiotics, Antitubercular - administration & dosage | Fluoroquinolones - administration & dosage | Antibiotics, Antitubercular - pharmacokinetics | Benzoxazines - administration & dosage | HIV Infections - virology | Africa | Fluoroquinolones - therapeutic use | Coinfection - virology | Benzoxazines - therapeutic use | Coinfection - microbiology | Fluoroquinolones - blood | Antibiotics, Antitubercular - therapeutic use | HIV Infections - complications | HIV Infections - drug therapy | Index Medicus | Original Research
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2015, Volume 191, Issue 3, pp. 333 - 343
Journal Article
by Thwaites, Guy E and Thwaites, Guy and Scarborough, Matthew and Szubert, Alex and Szubert, Alexander and Nsutebu, Emmanuel and Tilley, Robert and Greig, Julia and Wyllie, Sarah A and Wyllie, Sarah and Wilson, Peter and Wilson, Jonathan and Wilson, Helen and Wilson, Hesther and Auckland, Cressida and Cairns, Janet and Ward, Denise and Lal, Pankaj and Guleri, Achyut and Jenkins, Neil and Sutton, Julian and Wiselka, Martin and Armando, Gonzalez-Ruiz and Graham, Clive and Chadwick, David and Chadwick, Paul R and Chadwick, Paul and Barlow, Gavin and Gordon, Nicola Claire and Gordon, N Claire and Gordon, Joanne and Young, Bernadette and Meisner, Sarah and McWhinney, Paul and Price, David Ashley and Price, David A and Price, Suzanne and Price, James and Harvey, David and Nayar, Deepa and Jeyaratnam, Dakshika and Planche, Tim and Minton, Jane and Hudson, Fleur and Hopkins, Susan and Williams, Joanne and Williams, Claire and Williams, John and Williams, Sue and Török, M Estee and Török, M Estée and Llewelyn, Martin J and Llewelyn, Martin and Edgeworth, Jonathan D and Walker, A Sarah and Walker, Ann Sarah and Walker, Colin and Kamfose, Musa and de Veciana, Ana and Peto, Leon and Pill, Gemma and Clarke, Tiphanie and Clarke, Anne and Watson, Cordelia and Watson, Laura and Griffiths, Dai and Vaughn, Ali and Anson, Jim and Anson, Luke and Liu, Elian and Perera, Sanuki and Rylance-Knight, Lydia and Cantell, Carmen and Moroney, Ruth and Bisnauthsing, Karen and Querol-Rubiera, Antonio and Gibbs, Charlotte and Patel, Amita and Patel, Bijal and Hemsley, Carolyn and Goodman, Anna L and Wyncoll, Duncan and Biswas, Jason and Fitzpatrick, Jennifer and Roberts, Lizzie and Roberts, Paul and Millard, James and Stone, Neil and Cape, Angela and Hurley, Lisa and Tam, Chi Kai and Hoyle, Marie-Claire and Maitland, Kate and Trainor, Leona and Reynolds, Helen and Harrison, Melanie and Harrison, Jennifer and Lewis, Joseph and Folb, Jonathan and Goodwin, Lynsey and ... and UKCIRG and United Kingdom Clinical Infection Research Group (UKCIRG)
The Lancet, ISSN 0140-6736, 02/2018, Volume 391, Issue 10121, pp. 668 - 678
Journal Article