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Journal of the National Cancer Institute, ISSN 0027-8874, 11/2011, Volume 103, Issue 22, pp. 1665 - 1675
Recent advances in tumor biology have made remarkable achievements in the development of therapy for metastatic castrate-resistant prostate cancer. These... 
GROWTH-FACTOR RECEPTOR | CONTROLLED-TRIAL | ANTIANGIOGENIC THERAPY | ONCOLOGY | RANDOMIZED PHASE-II | BONE METASTASES | C-MET | SIPULEUCEL-T APC8015 | ABIRATERONE ACETATE | TUMOR MICROENVIRONMENT | ANGIOGENESIS INHIBITION | Cancer Vaccines - pharmacology | Humans | Male | Antineoplastic Agents - therapeutic use | Bevacizumab | Prostatic Neoplasms - immunology | RANK Ligand - pharmacology | Receptors, Androgen - drug effects | Treatment Failure | Prostatic Neoplasms - drug therapy | Phenylthiohydantoin - pharmacology | Tumor Microenvironment - drug effects | Dasatinib | Antibodies, Monoclonal - pharmacology | Angiogenesis Inhibitors - pharmacology | Clusterin - pharmacology | Pyrimidines - pharmacology | Denosumab | Prostate-Specific Antigen - blood | Orchiectomy | Signal Transduction - drug effects | Anilides - pharmacology | Mice | Receptor Cross-Talk - drug effects | Endothelin-1 - antagonists & inhibitors | Immunotherapy - methods | Taxoids - pharmacology | Ipilimumab | Tissue Extracts - pharmacology | Bone Remodeling - drug effects | Pyrrolidines - pharmacology | Antibodies, Monoclonal, Humanized - pharmacology | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Molecular Targeted Therapy - methods | Prostatic Neoplasms - pathology | Antineoplastic Agents, Hormonal - pharmacology | Androstenols - pharmacology | Androstenes | Clinical Trials as Topic | Mice, SCID | Phenylthiohydantoin - analogs & derivatives | Biomarkers, Tumor - blood | Xenograft Model Antitumor Assays | Cancer Vaccines - immunology | Pyrroles - pharmacology | Animals | RANK Ligand - antagonists & inhibitors | Pyridines - pharmacology | Thiazoles - pharmacology | Immune response | Development and progression | Cellular signal transduction | Research | Drug therapy | Health aspects | Prostate cancer | Risk factors | Review
Journal Article
Immunopharmacology and immunotoxicology, ISSN 0892-3973, 1987
Journal
Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2003, Volume 2, Issue 10, pp. 971 - 984
Journal Article
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 1, pp. e0210608 - e0210608
Standard treatment, unfortunately, yields a poor prognosis for patients with primary or metastatic cancers in the central nervous system, indicating a... 
CELLS | APOPTOSIS | ACTIVATION | MELANOMA | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | IMMUNOTOXIN THERAPY | PROTEOGLYCAN | INHIBITOR | PROMOTES | EXPRESSION | Thiophenes - therapeutic use | Humans | Antineoplastic Agents - therapeutic use | Furin - pharmacology | Immunotoxins - pharmacology | Biphenyl Compounds - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Brain Neoplasms - secondary | Isoquinolines - pharmacology | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Time Factors | Nitrophenols - therapeutic use | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Cell Death - drug effects | Benzothiazoles - pharmacology | Endocytosis - drug effects | Chondroitin Sulfate Proteoglycans - metabolism | Thiophenes - pharmacology | Exotoxins - pharmacology | Piperazines - therapeutic use | Pyrimidines - pharmacology | Brain Neoplasms - drug therapy | Sulfonamides - pharmacology | Piperazines - pharmacology | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Immunotoxins - therapeutic use | Signal Transduction - drug effects | Sulfonamides - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Models, Biological | Pyrimidines - therapeutic use | Survival Analysis | Cell Line, Tumor | Isoquinolines - therapeutic use | Benzothiazoles - therapeutic use | Care and treatment | Prognosis | Brain tumors | Central nervous system diseases | Research | Antibody-toxin conjugates | Health aspects | Brain | Animal models | Bcl-2 protein | Laboratories | Toxicity | Brain cancer | Xenotransplantation | Lung cancer | Central nervous system | Glioblastoma | Cytotoxicity | Metastasis | Neurosurgery | Kinases | Cancer therapies | Anticancer properties | Metastases | Proteins | Xenografts | Antigens | Proteoglycans | Melanoma | Poly(ADP-ribose) polymerase | Breast cancer | Pharmacology | Tumor cell lines | Patients | Chemical compounds | Immunotoxins | Pathology | Chemotherapy | Pancreatic cancer | Antitumor activity | Sensitivity enhancement | Chondroitin sulfate | Synergistic effect | Apoptosis | Tumors | Index Medicus
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 10/2007, Volume 85, Issue 7, pp. 558 - 566
It has been recognized that protease‐activated receptors (PARs), interleukin (IL)‐4 and IL‐6 are involved in the pathogenesis of allergic diseases, and that... 
mast cell | IL‐4 | IL‐12 | trypsin | protease‐activated receptor | tryptase | IL-4 | Trypsin | Mast cell | Protease-activated receptor | IL-12 | Tryptase | SERINE PROTEINASES | THROMBIN RECEPTORS | HISTAMINE-RELEASE | INDUCTION | IMMUNOLOGY | HUMAN AIRWAYS | CELL BIOLOGY | SMOOTH-MUSCLE | INTERFERON-GAMMA | IN-VIVO | protease-activated receptor | VASCULAR ENDOTHELIAL-CELLS | INFLAMMATORY MEDIATORS | Receptors, Proteinase-Activated - metabolism | Nitriles - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Receptors, Proteinase-Activated - genetics | Trypsin - pharmacology | Mast Cells - metabolism | Flavonoids - pharmacology | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-12 - pharmacology | Butadienes - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Imidazoles - pharmacology | Tyrphostins - pharmacology | Mast Cells - drug effects | Gene Expression Regulation - drug effects | Interleukin-4 - secretion | Animals | Tryptases - pharmacology | Mice | Pyridines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Tyrphostins, pharmacology | Up-Regulation | Chromones, pharmacology | Trypsin, pharmacology | Humans | Imidazoles, pharmacology | Tryptases, pharmacology | Oligopeptides, pharmacology | Interleukin-12, pharmacology | Flow Cytometry | Pyridines, pharmacology | Polymerase Chain Reaction | Receptor, PAR-1, drug effects | Morpholines, pharmacology | RNA, Messenger, metabolism | Flavonoids, pharmacology | Receptor, PAR-2, drug effects | Receptors, Thrombin, drug effects | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Butadienes, pharmacology | Down-Regulation | Mast Cells, drug effects | Interleukin-6, secretion | Nitriles, pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4, secretion | Fluorescent Antibody Technique
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 2015, Volume 59, Issue 10, pp. 5892 - 5902
Ebola virus can cause severe hemorrhagic disease with high fatality rates. Currently, no specific therapeutic agent or vaccine has been approved for treatment... 
ANTIBODY-DEPENDENT ENHANCEMENT | NONHUMAN-PRIMATES | VIRAL HEMORRHAGIC FEVERS | WEST-AFRICA | POSTEXPOSURE PROTECTION | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | T-705 FAVIPIRAVIR | PROVIDES PROTECTION | CONVALESCENT PLASMA | FILOVIRUS INFECTION | MOLECULAR-MECHANISMS | Cytosine - analogs & derivatives | RNA, Small Interfering - genetics | Ebolavirus - metabolism | Humans | Benzofurans - pharmacology | Androstenes - pharmacology | Ebolavirus - growth & development | Stilbenes - pharmacology | Ebolavirus - genetics | Ebolavirus - drug effects | Hemorrhagic Fever, Ebola - virology | Hemorrhagic Fever, Ebola - mortality | Cytosine - pharmacology | Hemorrhagic Fever, Ebola - drug therapy | Disease Models, Animal | Amides - pharmacology | Immune Sera - pharmacology | Virus Replication - drug effects | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Antibodies, Monoclonal - pharmacology | Hemorrhagic Fever, Ebola - pathology | Organophosphonates - pharmacology | Animals | Disease Outbreaks - prevention & control | Amidines - pharmacology | Pyrazines - pharmacology | RNA, Small Interfering - metabolism | Life Sciences | Human health and pathology | Social Anthropology and ethnology | Immunology | Sociology | Biological anthropology | Humanities and Social Sciences | Cellular Biology | Minireviews
Journal Article
British journal of pharmacology, ISSN 0007-1188, 2018, Volume 175, Issue 1, pp. 3 - 17
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 5/2012, Volume 69, Issue 5, pp. 1229 - 1240
...Cancer Chemother Pharmacol (2012) 69:1229–1240 DOI 10.1007/s00280-011-1817-3 123 ORIGINAL ARTICLE Clinical pharmacology of trastuzumab emtansine (T-DM1... 
Trastuzumab emtansine | Medicine & Public Health | Cancer Research | Oncology | Antibody–drug conjugate | T-DM1 | Breast cancer | Pharmacology/Toxicology | HER2 | Antibody-drug conjugate | BREAST-CANCER | ONCOLOGY | PHARMACOLOGY & PHARMACY | MBC | Antibodies, Monoclonal, Humanized - therapeutic use | Enzyme-Linked Immunosorbent Assay | Maytansine - analogs & derivatives | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Treatment Outcome | Maytansine - therapeutic use | Breast Neoplasms - drug therapy | Maytansine - pharmacology | Tandem Mass Spectrometry | Antibodies, Monoclonal, Humanized - pharmacokinetics | Breast Neoplasms - pathology | Antibodies, Monoclonal, Humanized - pharmacology | Maytansine - pharmacokinetics | Aged, 80 and over | Chromatography, Liquid | Adult | Female | Aged | Trastuzumab | Care and treatment | Oncology, Experimental | Antibodies | Polymerization | Liquid chromatography | Metastasis | Research | Antineoplastic agents | Chromatography | Viral antibodies | Antimitotic agents | Epidermal growth factor | Drug therapy | Mass spectrometry | Cancer | Thrombocytopenia | Epidermal growth factor receptors | Liver | Data processing | Mass spectroscopy | Pharmacology | transaminase | ErbB-2 protein | trastuzumab | Immunogenicity | Microtubules | thioethers | Pharmacokinetics | Platelets | Enzyme-linked immunosorbent assay | Toxicology | Original
Journal Article