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1. Anti-idiotypic vaccines
by Cazenave, Pierre-André
1991, Progress in vaccinology, ISBN 9780387971421, Volume 3, xii, 139
Anti-idiotypic vaccines | Antibodies, Anti-Idiotypic | Vaccines | immunology | Immunotherapy | Anti-idiotypic antibodies
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2. Full Text Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation
by van Schouwenburg, Pauline A and van de Stadt, Lotte A and de Jong, Rob N and van Buren, Esther E L and Kruithof, Simone and de Groot, Els and Hart, Margreet and van Ham, S Marieke and Rispens, Theo and Aarden, Lucien and Wolbink, Gerrit Jan and Wouters, Diana
Annals of the Rheumatic Diseases, ISSN 0003-4967, 01/2013, Volume 72, Issue 1, pp. 104 - 109
Objectives Millions of patients worldwide are treated with therapeutic monoclonal antibodies. These biological therapeutics can be immunogenic, resulting in... 
RHEUMATOID-ARTHRITIS | IMMUNOGENICITY | IMMUNE-SYSTEM | DISEASE | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | CLINICAL-RESPONSE | Antibody Specificity | Antibodies, Monoclonal, Humanized - therapeutic use | Enzyme-Linked Immunosorbent Assay | Arthritis, Rheumatoid - blood | Antibodies, Anti-Idiotypic - blood | Humans | Antirheumatic Agents - immunology | Antibodies, Anti-Idiotypic - immunology | Antibodies, Neutralizing - immunology | Arthritis, Rheumatoid - drug therapy | Adalimumab | Antibodies, Monoclonal, Humanized - immunology | Antigen-Antibody Complex - immunology | Arthritis, Rheumatoid - immunology | Antibodies, Neutralizing - blood | Antirheumatic Agents - therapeutic use | Drugs | Dose-response relationship (Biochemistry) | Immune response | Tumor necrosis factor inhibitors | Rheumatoid arthritis | Dosage and administration | Product/Service Evaluations | Research | Drug therapy | Studies | Antigens | Tumor necrosis factor-TNF | Immunoglobulins | Patients | Binding sites
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3. Monoclonal and anti-idiotypic antibodies
: probes for receptor structure and function
by Venter, J. Craig and Fraser, Claire M and Lindstrom, Jon
1984, ISBN 9780845137031, Volume 4., xii, 194
Monoclonal antibodies | Cell receptors | Immunoglobulin idiotypes
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4. Full Text Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies
by Lemaire, M and D'Huyvetter, M and Lahoutte, T and Van Valckenborgh, E and Menu, E and De Bruyne, E and Kronenberger, P and Wernery, U and Muyldermans, S and Devoogdt, N and Vanderkerken, K
Leukemia, ISSN 0887-6924, 02/2014, Volume 28, Issue 2, pp. 444 - 447
ANTIBODIES | MODEL | ONCOLOGY | HEMATOLOGY | CANCER-THERAPY | Antibodies, Anti-Idiotypic - pharmacology | Humans | Radioimmunotherapy | Tomography, Emission-Computed, Single-Photon | Single-Domain Antibodies - administration & dosage | Technetium | X-Ray Microtomography | Single-Domain Antibodies - pharmacology | Antibodies, Anti-Idiotypic - administration & dosage | Multiple Myeloma - pathology | Animals | Mice | Multiple Myeloma - radiotherapy | Radiopharmaceuticals | Disease Models, Animal | Viral antibodies | Care and treatment | Usage | Multiple myeloma | Antibodies | Diagnosis | Research | Health aspects
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5. Full Text Efficacy of intravenous immunoglobulin (IVIG) affinity‐purified anti‐desmoglein anti‐idiotypic antibodies in the treatment of an experimental model of pemphigus vulgaris
by Mimouni, D and Blank, M and Payne, A. S and Anhalt, G. J and Avivi, C and Barshack, I and David, M and Shoenfeld, Y
Clinical & Experimental Immunology, ISSN 0009-9104, 12/2010, Volume 162, Issue 3, pp. 543 - 549
Summary Pemphigus vulgaris is a rare life‐threatening autoimmune bullous disease caused by immunoglobulin G (IgG) autoantibodies directed against desmogleins 1... 
IVIG | autoimmunity | pemphigus | autoantibodies | desmoglein | Autoimmunity | Desmoglein | Autoantibodies | Pemphigus | ANTIPHOSPHOLIPID ANTIBODIES | IMMUNE GLOBULIN | CELL-SURFACE | CROSS-REACTIVE IDIOTYPE | BLISTER FORMATION | IMMUNOLOGY | CULTURED KERATINOCYTES | IMMUNOELECTRON MICROSCOPY | IN-VITRO | THERAPEUTIC-USE | Antibodies, Anti-Idiotypic - adverse effects | Autoantibodies - metabolism | Skin - metabolism | Humans | Immunoglobulins, Intravenous - adverse effects | Pemphigus - physiopathology | Single-Chain Antibodies - administration & dosage | Immunoglobulins, Intravenous - administration & dosage | Pemphigus - drug therapy | Antibodies, Anti-Idiotypic - administration & dosage | Single-Chain Antibodies - metabolism | Single-Chain Antibodies - genetics | Protein Engineering | Skin - pathology | Disease Models, Animal | Skin - immunology | Animals, Newborn | Desmoglein 3 - immunology | Immunoglobulins, Intravenous - isolation & purification | Mice, Inbred C57BL | Desmoglein 1 - immunology | Antibodies, Anti-Idiotypic - immunology | Autoantibodies - administration & dosage | Epitopes | Antibodies, Anti-Idiotypic - isolation & purification | Autoantibodies - immunology | Animals | Pemphigus - immunology | Mice | Acantholysis - prevention & control | Immunoglobulins, Intravenous - immunology | Skin - drug effects | Medical colleges | Analysis | Immunoglobulin G | Enzyme-linked immunosorbent assay | Dermatology | Geriatrics | Neonates | Animal models | Immunoglobulins | Intravenous administration | Bullous diseases | desmoglein 1 | pemphigus vulgaris | Models | Skin | Immunofluorescence | Animal Models
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6. Full Text Aβ anti-idiotypic antibodies are present in intravenous immunoglobulin and are produced in mice following its administration
by Loeffler, David A and Klaver, Andrea C and Coffey, Mary P
Autoimmunity, ISSN 0891-6934, 6/2015, Volume 48, Issue 4, pp. 196 - 200
Abstract The effects of intravenous immunoglobulin (IVIG) products were recently examined in patients with Alzheimer's disease (AD). Although encouraging... 
IVIG | autoimmunity | Alzheimer's disease | mice | immunotherapy | Autoimmunity | Mice | Immunotherapy | IMMUNE SYSTEM | ALZHEIMERS-DISEASE | AMYLOID-BETA | IMMUNOLOGY | NETWORK THEORY | Animals | Antibody Specificity - immunology | Humans | Peptide Fragments - immunology | Alzheimer Disease - drug therapy | Antibodies, Anti-Idiotypic - immunology | Immunoglobulins, Intravenous - administration & dosage | Amyloid beta-Peptides - immunology | Male | Alzheimer Disease - immunology | Immunoglobulins, Intravenous - immunology
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7. Full Text Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics
by Adamson, H and Nicholl, A and Tiede, C and Tang, AA and Davidson, A and Curd, H and Wignall, A and Ford, R and Nuttall, J and McPherson, MJ and Johnson, M and Tomlinson, DC
BIOTECHNIQUES, ISSN 0736-6205, 09/2019, Volume 67, Issue 6, pp. 261 - 269
Therapeutic antibodies are the fastest growing class of drugs in the treatment of cancer, and autoimmune and inflammatory diseases that require the concomitant... 
biotherapeutics | pharmacokinetics | Affimer reagents | diagnostics | anti-idiotypic | LINKED-IMMUNOSORBENT-ASSAY | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | VALIDATION | ANTIBODY | SERUM | PEPTIDE | PHAGE | DISPLAY | PROTEINS | BINDING
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8. Full Text Exploring the effects of omalizumab in allergic asthma: An analysis of biomarkers in the EXTRA study
by Hanania, Nicola A and Wenzel, Sally and Roseń, Karin and Hsieh, Hsin-Ju and Mosesova, Sofia and Choy, David F and Lal, Preeti and Arron, Joseph R and Harris, Jeffrey M and Busse, William
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2013, Volume 187, Issue 8, pp. 804 - 811
Rationale: For many patients with asthma, allergic airway inflammation is primarily a Th2-weighted process; however, heterogeneity in patterns of inflammation... 
Immunoglobulin E | Fractional exhaled nitric oxide | Severe asthma | Eosinophil | Periostin | periostin | SAFETY | MONOCLONAL-ANTIBODY | IL-13 | immunoglobulin E | THERAPY | fractional exhaled nitric oxide | RESPIRATORY SYSTEM | INFLAMMATION | severe asthma | EXACERBATIONS | eosinophil | ANTI-IGE ANTIBODY | CRITICAL CARE MEDICINE | Anti-Asthmatic Agents - adverse effects | Antibodies, Anti-Idiotypic - adverse effects | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Omalizumab | Male | Nitric Oxide - analysis | Young Adult | Antibodies, Anti-Idiotypic - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Adult | Female | Antibodies, Anti-Idiotypic - therapeutic use | Child | Cell Adhesion Molecules - blood | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Biomarkers - analysis | Breath Tests | Asthma - drug therapy | Asthma - genetics | Disease Progression | Adolescent | Aged | Anti-Asthmatic Agents - administration & dosage | Eosinophils
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9. Full Text Protective role of anti-idiotypic antibodies in autoimmunity - Lessons for type 1 diabetes
by Hampe, Christiane S
Autoimmunity, ISSN 0891-6934, 06/2012, Volume 45, Issue 4, pp. 320 - 331
Circulating autoantibodies to beta cell antigens are present in the majority of patients with Type 1 diabetes. These autoantibodies can be detected before and... 
Idiotypic Network Hypothesis | type 1 diabetes | autoimmune disease | autoantibodies | glutamate decarboxylase | SYSTEMIC-LUPUS-ERYTHEMATOSUS | INTRAVENOUS GAMMA-GLOBULIN | DNA ANTIBODIES | IMMUNOGLOBULIN VARIABLE-REGION | IMMUNOLOGY | IDIOPATHIC THROMBOCYTOPENIC PURPURA | ANTIRIBOSOMAL P AUTOANTIBODIES | B-CELL | ANTI-IDIOTYPIC-ANTIBODY | MYASTHENIA-GRAVIS | T-CELLS | Autoimmunity | Autoantibodies - immunology | Antibodies, Anti-Idiotypic - blood | Autoantigens - immunology | Humans | Autoimmune Diseases - immunology | Antibodies, Anti-Idiotypic - immunology | T-Lymphocytes - immunology | Diabetes Mellitus, Type 1 - immunology | Glutamate Decarboxylase - immunology | Insulin-Secreting Cells - immunology
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10. Full Text Anti-idiotypic nanobody-alkaline phosphatase fusion proteins: Development of a one-step competitive enzyme immunoassay for fumonisin B1 detection in cereal
by Shu, Mei and Xu, Yang and Liu, Xing and Li, Yanping and He, Qinghua and Tu, Zhui and Fu, Jinheng and Gee, Shirley J and Hammock, Bruce D
Analytica Chimica Acta, ISSN 0003-2670, 06/2016, Volume 924, pp. 53 - 59
A rapid and sensitive one-step competitive enzyme immunoassay for the detection of FB1 was developed. The anti-idiotypic nanobody–alkaline phosphatase... 
One-step immunoassay | Nanobody | Anti-idiotypic antibody
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11. Full Text Preventive DNA vaccination against CEA-expressing tumors with anti-idiotypic scFv6.C4 DNA in CEA-expressing transgenic mice
by Denapoli, Priscila M. A and Denapoli, Priscila M. A and Zanetti, Bianca F and Zanetti, Bianca F and dos Santos, Adara A and dos Santos, Adara A and de Moraes, Jane Z and de Moraes, Jane Z and Han, Sang W and Han, Sang W
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 3/2017, Volume 66, Issue 3, pp. 333 - 342
Carcinoembryonic antigen (CEA) is expressed during embryonic life and in low level during adult life. Consequently, the CEA is recognized by the immune system... 
DNA vaccine | Carcinoembryonic antigen | Immunology | Anti-idiotypic antibody | Medicine & Public Health | Single-chain fragment variable | Colorectal cancer | Oncology | Cancer Research | Immunological tolerance | HUMAN COLON | IMMUNE-RESPONSE | LOCALIZATION | MIMICRY | ELECTROPORATION | CARCINOEMBRYONIC ANTIGEN CEA | MONOCLONAL-ANTIBODY | INDUCTION | IMMUNOLOGY | CANCER-PATIENTS | ONCOLOGY | VACCINES | Animals | Colorectal Neoplasms - immunology | Transfection | Carcinoembryonic Antigen - immunology | Humans | Vaccines, DNA - immunology | Colorectal Neoplasms - prevention & control | Mice, Transgenic | Mice | Colorectal Neoplasms - pathology | Vaccines, DNA - administration & dosage | Disease Models, Animal | Genetic vectors | Vaccination | DNA | Melanoma | Genetic research | Genetic engineering | T cells | Gene therapy | CEA (Oncology) | Tumors
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12. Full Text Anti-idiotypic antibody specific to GAD65 autoantibody prevents type 1 diabetes in the NOD mouse
by Wang, Xin and Zhang, Aixia and Liu, Yu and Chen, Shi and Feng, Zhenqing and Shang, Wenbin and Maziarz, Marlena and Radtke, Jared and Hampe, Christiane S
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e32515
Overt autoantibodies to the smaller isoform of glutamate decarboxylase (GAD65Ab) are a characteristic in patients with Type 1 diabetes (T1D). Anti-idiotypic... 
B-LYMPHOCYTES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ANTIRIBOSOMAL P AUTOANTIBODIES | DNA ANTIBODIES | ACID DECARBOXYLASE GAD | BIOLOGY | GRAVES-DISEASE | ANTIGEN-PRESENTING CELLS | IDIOTYPIC ANTIBODIES | MONOCLONAL-ANTIBODIES | NETWORK THEORY | Humans | Middle Aged | Diabetes Mellitus, Type 1 - genetics | Glutamate Decarboxylase - genetics | Male | Glutamate Decarboxylase - physiology | Sequence Analysis, DNA | Animals | Protein Isoforms | Adult | Antibodies, Anti-Idiotypic - chemistry | Female | Mice, Inbred NOD | Aged | Mice | Mice, Inbred BALB C | Diabetes Mellitus, Type 1 - immunology | Binding Sites | Antibodies, Monoclonal - chemistry | Disease Models, Animal | Prevention | Autoimmunity | Autoantibodies | Type 1 diabetes | Monoclonal antibodies | Glutamate decarboxylase | Enzyme-linked immunosorbent assay | Insulitis | Disease | Pathogenesis | Antibodies | Leukocytes (mononuclear) | Diabetes mellitus (insulin dependent) | Lymphocytes | Rodents | Pancreas | Antigens | Immunoglobulins | Diabetes mellitus | T cell receptors | Patients | Hospitals | Acids | Infiltration | Diabetes | Autoimmune diseases | Binding sites | Endocrinology | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
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13. Full Text Omalizumab for asthma in adults and children
by Normansell, Rebecca and Normansell, Rebecca and Walker, Samantha and Walker, Samantha and Milan, Stephen J and Milan, Stephen J and Walters, E Haydn and Walters, E. Haydn and Nair, Parameswaran and Nair, Parameswaran
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 1, Issue 1, p. CD003559
Background Asthma is a respiratory (airway) condition that affects an estimated 300 million people worldwide and is associated with significant morbidity and... 
Adrenal Cortex Hormones [therapeutic use] | Humans | SEVERE ALLERGIC-ASTHMA | PULMONARY-FUNCTION | SPUTUM HYALURONAN | ANTIIMMUNOGLOBULIN-E ANTIBODY | Randomized Controlled Trials as Topic | Antibodies, Monoclonal, Humanized | ADD-ON THERAPY | MEDICINE, GENERAL & INTERNAL | Antibodies, Anti-Idiotypic [therapeutic use] | Antibodies, Monoclonal [therapeutic use] | SEVERE PERSISTENT ASTHMA | DOUBLE-BLIND | Adult | HUMANIZED MONOCLONAL-ANTIBODY | QUALITY-OF-LIFE | Immunoglobulin E [blood; immunology] | ANTI-IGE ANTIBODY | Asthma [drug therapy immunology] | Chronic Disease | Child | Anti-Asthmatic Agents [therapeutic use] | Antibodies, Monoclonal, Humanized - therapeutic use | Anti-Asthmatic Agents - therapeutic use | Omalizumab | Adrenal Cortex Hormones - therapeutic use | Asthma - drug therapy | Immunoglobulin E - blood | Antibodies, Anti-Idiotypic - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Immunoglobulin E - immunology | Injections, Subcutaneous | Asthma - immunology | Anti-Asthmatic Agents - administration & dosage | Antibodies, Anti-Idiotypic - therapeutic use
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