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PLoS ONE, ISSN 1932-6203, 2008, Volume 3, Issue 12, pp. e3942 - e3942
BACKGROUND: The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody... 
BIOLOGY | Influenza A Virus, H1N1 Subtype - immunology | Humans | Molecular Sequence Data | Neutralization Tests | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Peptide Library | Immunoglobulin M - immunology | Antibody Specificity - immunology | B-Lymphocytes - virology | Influenza, Human - virology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Immunologic Memory - immunology | Protein Structure, Tertiary | Amino Acid Sequence | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Antibodies, Monoclonal - isolation & purification | Antibodies, Viral - isolation & purification | Cross Reactions | Animals | B-Lymphocytes - immunology | Influenza A Virus, H5N1 Subtype - immunology | Antibodies, Viral - chemistry | Dogs | Hydrophobic and Hydrophilic Interactions | Antibodies, Viral - immunology | Mice | Tissue Donors | Binding Sites, Antibody | Influenza, Human - prevention & control | Influenza, Human - immunology | Immunoglobulin M | Pandemics | Laboratories | Prophylaxis | H alpha line | Viruses | Infections | Vaccines | Hydrophobicity | Avian flu | Proteins | Hemagglutinins | Antigens | Immunological memory | Memory cells | Immunoglobulins | Therapeutic applications | Mortality | Glycoprotein | Antigenic variants | Immune response (humoral) | Lymphocytes B | Neutralizing | Influenza | Monoclonal antibodies | Ligands | Combinatorial analysis | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2008, Volume 453, Issue 7195, pp. 667 - 671
Journal Article
Science, ISSN 0036-8075, 8/2010, Volume 329, Issue 5993, pp. 856 - 861
Cross-reactive neutralizing antibodies (NAbs) are found in the sera of many HIV-1-infected individuals, but the virologie basis of their neutralization remains... 
Proteins | Reactivity | Infectious diseases | B lymphocytes | Enzyme linked immunosorbent assay | REPORTS | Antibodies | Research facilities | Viruses | Amino acids | HIV 1 | INDIVIDUALS | PANEL | IMMUNOGENICITY | VIRUS | SPECIFICITIES | MULTIDISCIPLINARY SCIENCES | HIGH-AFFINITY | GP120 | GLYCOPROTEIN | TYPE-1 INFECTION | BREADTH | Antibody Specificity | Humans | Molecular Sequence Data | Neutralization Tests | HIV Antibodies - isolation & purification | HIV Envelope Protein gp120 - metabolism | Epitopes - immunology | Genes, Immunoglobulin Heavy Chain | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Drug Design | Protein Engineering | HIV Envelope Protein gp120 - chemistry | Antibodies, Monoclonal - immunology | Recombinant Proteins - metabolism | CD4 Antigens - immunology | Enzyme-Linked Immunosorbent Assay | Genes, Immunoglobulin Light Chain | HIV Infections - virology | Recombinant Proteins - chemistry | Antibodies, Monoclonal - isolation & purification | HIV-1 - genetics | Antibodies, Neutralizing - isolation & purification | Cross Reactions | HIV-1 - immunology | B-Lymphocytes - immunology | Recombinant Proteins - immunology | AIDS Vaccines | Binding Sites, Antibody | CD4 Antigens - metabolism | Monoclonal antibodies | Immunoglobulins | Research | HIV (Viruses) | Glycoproteins | Immunology | Human immunodeficiency virus--HIV | Index Medicus | Binding | Envelopes | Genes | Neutralizing | Glycoprotein | Circulating | Vaccines
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7467, pp. 439 - 443
Broadly neutralizing antibodies reactive against most and even all variants of the same viral species have been described for influenza and HIV-1 (ref. 1).... 
IN-VITRO | MEMORY B-CELLS | TRACT DISEASE | MULTIDISCIPLINARY SCIENCES | HUMAN METAPNEUMOVIRUS | FUSION PROTEIN | ELECTRON-MICROSCOPY | INFECTION | RESPIRATORY SYNCYTIAL VIRUS | YOUNG-CHILDREN | F-GLYCOPROTEIN | Humans | Immunoglobulin Variable Region - chemistry | Paramyxoviridae - classification | Pneumovirus Infections - prevention & control | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Immunoglobulin Variable Region - immunology | Respiratory Syncytial Virus Infections - immunology | Viral Fusion Proteins - immunology | Murine pneumonia virus - immunology | Epitopes - immunology | Immunoglobulin Light Chains - chemistry | Antibodies, Neutralizing - immunology | Antibody Specificity - immunology | Paramyxoviridae Infections - virology | Viral Fusion Proteins - chemistry | Cattle | Antibodies, Neutralizing - therapeutic use | Respiratory Syncytial Virus Infections - prevention & control | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus Infections - virology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Immunoglobulin Light Chains - immunology | Amino Acid Sequence | Metapneumovirus - immunology | Paramyxoviridae Infections - therapy | Models, Molecular | Antibodies, Monoclonal - isolation & purification | Cross Reactions - immunology | Pneumovirus Infections - virology | Antibodies, Neutralizing - isolation & purification | Paramyxoviridae Infections - immunology | Pneumovirus Infections - immunology | Paramyxoviridae - immunology | Animals | Respiratory Syncytial Virus, Human - immunology | Antibodies, Neutralizing - chemistry | Viral Vaccines - chemistry | Mice | Paramyxoviridae Infections - prevention & control | Respiratory Syncytial Virus Infections - therapy | Viral Vaccines - immunology | Monoclonal antibodies | Paramyxoviruses | Control | Health aspects | Proteins | Competition | Viruses | Glycoproteins | Infections | Mutation | Index Medicus
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6044, pp. 843 - 850
Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V H 1-69 antibodies that broadly... 
Influenza A virus | RESEARCH ARTICLES | Vaccination | Cardiopulmonary resuscitation | Antibodies | Viruses | Orthomyxoviridae | Infections | Epitopes | H3N2 subtype influenza A virus | Crystal structure | FUSION | HEMAGGLUTININ | RECOGNITION | AVIAN INFLUENZA | SUBTYPES | MULTIDISCIPLINARY SCIENCES | VACCINATION | MONOCLONAL-ANTIBODIES | PEPTIDE | SEASON | Orthomyxoviridae Infections - prevention & control | Antibody Specificity | Humans | Molecular Sequence Data | Antigens, Viral - genetics | Crystallography, X-Ray | Neutralization Tests | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Epitopes - immunology | Antibodies, Neutralizing - immunology | Conserved Sequence | Influenza A Virus, H7N7 Subtype - immunology | Influenza A virus - immunology | Influenza, Human - therapy | Antibodies, Monoclonal - immunology | Amino Acid Sequence | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Models, Molecular | Antigens, Viral - chemistry | Antibodies, Monoclonal - isolation & purification | Influenza A Virus, H3N2 Subtype - immunology | Antibodies, Viral - isolation & purification | Antibodies, Neutralizing - isolation & purification | Antigens, Viral - immunology | Animals | Influenza Vaccines - immunology | Antibodies, Viral - immunology | Protein Conformation | Mice | Influenza A Virus, H7N7 Subtype - genetics | Mutation | Binding Sites, Antibody | Influenza, Human - prevention & control | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Influenza viruses | Influenza vaccines | Crystals | Monoclonal antibodies | Physiological aspects | Research | Properties | Structure | Vaccines | Influenza | Public health | Virology | Index Medicus | fusion | peptide | avian influenza | hemagglutinin | recognition | monoclonal-antibodies | season | vaccination | subtypes
Journal Article
Science, ISSN 0036-8075, 08/2016, Volume 353, Issue 6301, pp. 823 - 826
Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7633, pp. 443 - 447
Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that can cause severe disease, including congenital birth defects during pregnancy(1). To... 
PROTECTION | MULTIDISCIPLINARY SCIENCES | WEST-NILE-VIRUS | ENHANCEMENT | CROSS-REACTIVITY | INFECTION | MONOCLONAL-ANTIBODIES | EXPOSURE | PREGNANCY | Americas | Antibody Specificity | Epitope Mapping | Humans | Protein Multimerization | Fetal Diseases - prevention & control | Viral Proteins - immunology | Antibodies, Monoclonal - therapeutic use | Male | Zika Virus Infection - virology | Antibodies, Neutralizing - immunology | Antibodies, Neutralizing - therapeutic use | Female | Fetus - virology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Disease Models, Animal | Zika Virus - immunology | Zika Virus - growth & development | Antibodies, Viral - therapeutic use | Placenta - immunology | Viral Proteins - chemistry | Zika Virus Infection - pathology | Africa | Models, Molecular | Survival Rate | Virus Replication - immunology | Fetal Diseases - virology | Pregnancy | Animals | B-Lymphocytes - immunology | Asia | Antibodies, Neutralizing - chemistry | Fetal Diseases - immunology | Antibodies, Viral - chemistry | Viral Vaccines - chemistry | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Fetus - immunology | Mice | Infectious Disease Transmission, Vertical - prevention & control | Placenta - virology | Viral Vaccines - immunology | Viral antibodies | Antibodies | Health aspects | Proteins | Immunoglobulins | Zika virus | Fetuses | Viral infections | Index Medicus
Journal Article
by Liao, Hua-Xin and Lynch, Rebecca and Zhou, Tongqing and Gao, Feng and Munir Alam, S and Boyd, Scott D and Fire, Andrew Z and Roskin, Krishna M and Schramm, Chaim A and Zhang, Zhenhai and Zhu, Jiang and Shapiro, Lawrence and Mullikin, James C and Gnanakaran, S and Hraber, Peter and Wiehe, Kevin and Kelsoe, Garnett and Yang, Guang and Xia, Shi-Mao and Montefiori, David C and Parks, Robert and Lloyd, Krissey E and Scearce, Richard M and Soderberg, Kelly A and Cohen, Myron and Kamanga, Gift and Louder, Mark K and Tran, Lillian M and Chen, Yue and Cai, Fangping and Chen, Sheri and Moquin, Stephanie and Du, Xiulian and Gordon Joyce, M and Srivatsan, Sanjay and Zhang, Baoshan and Zheng, Anqi and Shaw, George M and Hahn, Beatrice H and Kepler, Thomas B and Korber, Bette T. M and Kwong, Peter D and Mascola, John R and Haynes, Barton F and Becker, Jesse and Benjamin, Betty and Blakesley, Robert and Bouffard, Gerry and Brooks, Shelise and Coleman, Holly and Dekhtyar, Mila and Gregory, Michael and Guan, Xiaobin and Gupta, Jyoti and Han, Joel and Hargrove, April and Ho, Shi-Ling and Johnson, Taccara and Legaspi, Richelle and Lovett, Sean and Maduro, Quino and Masiello, Cathy and Maskeri, Baishali and McDowell, Jenny and Montemayor, Casandra and Mulliki, James and Park, Morgan and Riebow, Nancy and Schandler, Karen and Schmidt, Brian and Sison, Christina and Stantripop, Mal and Thomas, James and Thomas, Pam and Vemulapalli, Meg and Young, Alice and NISC Comparative Sequencing Progra and NISC Comparative Sequencing Program
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 469 - 476
Current human immunodeficiency virus-1 (HIV-1) vaccines elicit strain-specific neutralizing antibodies. However, cross-reactive neutralizing antibodies arise... 
B-CELL RESPONSES | CONFORMATIONAL EPITOPE | POTENT NEUTRALIZATION | CD4 BINDING-SITE | VACCINE DESIGN | MULTIDISCIPLINARY SCIENCES | ENVELOPE GLYCOPROTEIN | HIV-1-INFECTED INDIVIDUALS | HUMAN MONOCLONAL-ANTIBODIES | SUBTYPE-B | IN-SITU PROTEOLYSIS | HIV Envelope Protein gp120 - genetics | Clone Cells - cytology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Crystallography, X-Ray | Neutralization Tests | Phylogeny | HIV Envelope Protein gp120 - metabolism | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | HIV Envelope Protein gp120 - chemistry | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Amino Acid Sequence | CD4 Antigens - immunology | Africa | Cells, Cultured | Models, Molecular | Antibodies, Neutralizing - genetics | Cross Reactions - immunology | HIV Antibodies - chemistry | HIV-1 - classification | Antibodies, Monoclonal - genetics | Cell Lineage | HIV-1 - immunology | CD4 Antigens - chemistry | Antibodies, Neutralizing - chemistry | Epitopes - chemistry | HIV Antibodies - genetics | Mutation | Evolution, Molecular | Monoclonal antibodies | AIDS vaccines | Genetic aspects | Research | HIV (Viruses) | Properties | Proteins | Plasma | Infections | Patients | Binding sites | Crystal structure | Index Medicus
Journal Article