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Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 08/2016, Volume 84, Issue 8, pp. 1162 - 1172
...‐neutralizing activity, while F8 has weak neutralizing activity. F5 buried a total of 1760 Å2 in complex with RTA and made contact with three prominent secondary structural... 
antibody | neutralizing | toxin | epitope | ANTIBODIES | IMMUNITY | MECHANISM | A-CHAIN | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | VACCINE | RECOMBINANT RICIN | BIOPHYSICS | MICE | Protein Subunits - immunology | Epitopes, B-Lymphocyte - chemistry | Humans | Crystallography, X-Ray | Epitopes, B-Lymphocyte - immunology | Structure-Activity Relationship | Single-Chain Antibodies - genetics | Ricin - chemistry | Complementarity Determining Regions - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Ricin - antagonists & inhibitors | Antibodies, Monoclonal - chemistry | Amino Acid Sequence | Gene Expression | Protein Structure, Secondary | Single-Chain Antibodies - pharmacology | Antibodies, Monoclonal - pharmacology | Recombinant Proteins - chemistry | Antibodies, Neutralizing - pharmacology | Antibodies, Neutralizing - genetics | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | B-Lymphocytes - chemistry | Ricin - immunology | Antibodies, Monoclonal - genetics | Camelids, New World | Sequence Alignment | Animals | B-Lymphocytes - immunology | Escherichia coli - genetics | Antibodies, Neutralizing - chemistry | Protein Binding | Protein Subunits - antagonists & inhibitors | Protein Subunits - chemistry | Binding Sites, Antibody | Single-Chain Antibodies - chemistry | Lectins | Enzymes | Structure | Analysis | Crystals | Antigenic determinants | BASIC BIOLOGICAL SCIENCES
Journal Article
Cell host & microbe, ISSN 1931-3128, 2016, Volume 19, Issue 6, pp. 800 - 813
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2016, Volume 113, Issue 3, pp. 704 - 709
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 41, pp. 16538 - 16543
Journal Article
Science translational medicine, ISSN 1946-6242, 2017, Volume 9, Issue 410, p. eaan8184
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2012, Volume 109, Issue 31, pp. 12680 - 12685
.... To investigate the role of the CH1 domain, we constructed IgA2 from the broadly neutralizing anti-HIV-1 2F5 IgG1, and compared 2F5 IgA2 and IgG binding affinity and functional activities... 
T lymphocytes | Isotypes | HIV | Epithelial cells | Antibodies | Viruses | Transcytosis | Infections | Epitopes | HIV 1 | Antibody structure | HIV-1 envelope gp41 | Mimotope | Mucosa | HIV-1 | IGA | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | GP41 | HUMAN MONOCLONAL-ANTIBODY | HUMAN-IMMUNODEFICIENCY-VIRUS | EPITHELIAL TRANSCYTOSIS | antibody structure | ANTIGEN-BINDING AFFINITY | mimotope | REGION | TYPE-1 | mucosa | Antibody Specificity | HIV Envelope Protein gp41 - genetics | HIV-1 - pathogenicity | HIV Envelope Protein gp41 - immunology | Humans | Acquired Immunodeficiency Syndrome - therapy | CD4-Positive T-Lymphocytes - immunology | Epitopes - immunology | Acquired Immunodeficiency Syndrome - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Immunoglobulin G - immunology | Immunoglobulin G - pharmacology | CD4-Positive T-Lymphocytes - virology | HIV Antibodies - pharmacology | Acquired Immunodeficiency Syndrome - transmission | Protein Structure, Secondary | Antibodies, Monoclonal - pharmacology | Cells, Cultured | Antibodies, Neutralizing - pharmacology | Antibodies, Neutralizing - genetics | Transcytosis - immunology | Epitopes - genetics | HIV-1 - genetics | Antibodies, Monoclonal - genetics | HIV-1 - immunology | Immunoglobulin G - genetics | Transcytosis - drug effects | Antibodies, Monoclonal - metabolism | HIV Antibodies - genetics | Viral antibodies | Antiviral agents | Physiological aspects | Research | Health aspects | Protein binding | Life Sciences | Biological Sciences
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2017, Volume 46, Issue 4, pp. 690 - 702
Broadly neutralizing antibodies (bnAbs) to HIV delineate vaccine targets and are prophylactic and therapeutic agents... 
broadly neutralizing antibody | HIV | PGT145 | trimer apex | envelope glycoprotein | cryo-electron microscopy | REFINEMENT | SYSTEM | PROTEIN | RECOGNITION | VALIDATION | IMMUNOLOGY | REVEAL | QUATERNARY | BINDING | FEATURES | REGION | Surface Plasmon Resonance | Epitopes - metabolism | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Protein Multimerization | Antibodies, Neutralizing - metabolism | Crystallography, X-Ray | env Gene Products, Human Immunodeficiency Virus - metabolism | Anions - chemistry | Epitopes - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HEK293 Cells | Polysaccharides - chemistry | Protein Domains | env Gene Products, Human Immunodeficiency Virus - chemistry | HIV Antibodies - metabolism | Amino Acid Sequence | HIV-1 - metabolism | Protein Structure, Secondary | Models, Molecular | Polysaccharides - immunology | Protein Binding - immunology | HIV Antibodies - chemistry | Polysaccharides - metabolism | Cryoelectron Microscopy | Sequence Homology, Amino Acid | HIV-1 - immunology | Antibodies, Neutralizing - chemistry | Epitopes - chemistry | Atomic force microscopy | Residues | Immunoglobulins | Quaternary | Envelope protein | Antibodies | Pharmacology | Vaccines | Electron microscopy | Chemical compounds | Transmission electron microscopy | Human immunodeficiency virus--HIV | Neutralizing | Canopies | Atomic structure | Dismantling | Symmetry | Immune system
Journal Article
Science, ISSN 0036-8075, 10/2017, Volume 358, Issue 6359, pp. 85 - 90
Journal Article
The FASEB journal, ISSN 1530-6860, 2015, Volume 29, Issue 5, pp. 1739 - 1753
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e20166
Journal Article