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Nature medicine, ISSN 1546-170X, 2019, Volume 25, Issue 3, pp. 496 - 506
Apolipoprotein-E (ApoE) has been implicated in Alzheimer's disease, atherosclerosis, and other unresolvable inflammatory conditions but a common mechanism of... 
IMMUNE | ALZHEIMERS-DISEASE | A-BETA | NEUROFIBRILLARY PATHOLOGY | ATHEROSCLEROSIS | NEURODEGENERATION | MICE | FACTOR-H BINDS | LASER-CAPTURE MICRODISSECTION | APOLIPOPROTEIN-E | MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Complement C5 | Complement C1q - immunology | Humans | Middle Aged | Choroid Plexus - immunology | Male | Leukocytes | Cognitive Dysfunction - immunology | Carotid Artery Diseases - pathology | Aged, 80 and over | Female | Plaque, Amyloid - immunology | Carotid Artery Diseases - immunology | Atherosclerosis - pathology | Atherosclerosis - immunology | Plaque, Amyloid - pathology | Choroid Plexus - pathology | Aorta - immunology | Cognitive Dysfunction - pathology | Mice, Knockout, ApoE | Aorta - pathology | Complement Pathway, Classical - immunology | Animals | Apolipoproteins E - immunology | Carotid Arteries - immunology | Brain - pathology | Amyloid beta-Peptides - immunology | Aged | Carotid Arteries - pathology | RNA, Small Interfering | Antigen-Antibody Complex - immunology | Protein Isoforms - immunology | Brain - immunology | Microscopy, Fluorescence | Cogeneration power plants | Analysis | Atherosclerosis | Lipids | Research | Apolipoproteins | Alzheimer's disease | Choroid plexus | Complex formation | Cognitive ability | Complement | Inflammation | siRNA | Ribonucleic acid--RNA | Arteries | Microglia | White blood cells | Proteins | Complement component C1q | Immune checkpoint | Apolipoprotein E | Arteriosclerosis | Isoforms | Attenuation | Infiltration | Plaques
Journal Article
Nature immunology, ISSN 1529-2916, 2015, Volume 16, Issue 8, pp. 819 - 828
... during peritoneal immunological challenges. FALC formation was induced by inflammation, which triggered the recruitment of myeloid cells that expressed tumor-necrosis factor (TNF... 
TUMOR-NECROSIS-FACTOR | LYMPHOTOXIN-BETA | INSULIN-RESISTANCE | IMMUNOGLOBULIN-M | KILLER T-CELLS | FOLLICULAR DENDRITIC CELLS | TYPE-2 IMMUNITY | IMMUNOLOGY | NATURAL IMMUNITY | MACROPHAGE POLARIZATION | ADIPOSE-TISSUE | Tumor Necrosis Factor-alpha - metabolism | Tumor Necrosis Factor-alpha - genetics | Lymphoid Tissue - immunology | Inflammation - metabolism | Flow Cytometry | Lymphocytes - immunology | Myeloid Cells - immunology | Natural Killer T-Cells - metabolism | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Chemokine CXCL13 - immunology | B-Lymphocytes - metabolism | Receptors, Tumor Necrosis Factor - genetics | Intra-Abdominal Fat - immunology | Lymphocytes - metabolism | Receptors, Tumor Necrosis Factor - metabolism | Chemokine CXCL13 - genetics | Mice, Inbred C57BL | Stromal Cells - metabolism | Lymphoid Tissue - metabolism | Mice, Transgenic | Stromal Cells - immunology | Inflammation - immunology | Intra-Abdominal Fat - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Lymphoid Tissue - cytology | Microscopy, Confocal | Animals | B-Lymphocytes - immunology | Chemokine CXCL13 - metabolism | Inflammation - genetics | Myeloid Cells - metabolism | Mice, Inbred BALB C | Receptors, Tumor Necrosis Factor - immunology | Natural Killer T-Cells - immunology | Viral antibodies | Usage | Tumor necrosis factor | Antibodies | Inflammation | B cells | Health aspects
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 10, p. e48111
Neutrophils (PMNs) and cytokines have a critical role to play in host defense and systemic inflammatory response syndrome (SIRS). Neutrophil extracellular... 
OXIDE-MEDIATED AUGMENTATION | IL-8 GENE-EXPRESSION | RESPIRATORY BURST | REACTIVE OXYGEN | POLYMORPHONUCLEAR LEUKOCYTES | INTERLEUKIN-1 BETA | MULTIDISCIPLINARY SCIENCES | OXYGEN SPECIES GENERATION | NITRIC-OXIDE | NECROSIS-FACTOR-ALPHA | SEVERE SEPSIS | Interleukin-8 - genetics | Interleukin-1beta - pharmacology | Reactive Oxygen Species - metabolism | Tetradecanoylphorbol Acetate - pharmacology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Neutrophil Activation - drug effects | Male | Interleukin-1beta - genetics | Actins - genetics | DNA - blood | Mitochondrial Proton-Translocating ATPases - genetics | Young Adult | Systemic Inflammatory Response Syndrome - blood | Reactive Oxygen Species - immunology | Inflammation Mediators - metabolism | Systemic Inflammatory Response Syndrome - immunology | Tumor Necrosis Factor-alpha - immunology | Adult | Female | Interleukin-8 - pharmacology | Cytokines - genetics | Neutrophils - metabolism | Cytokines - immunology | Inflammation Mediators - immunology | Neutrophil Activation - immunology | Peroxidase - immunology | DNA - immunology | Neutrophils - drug effects | Cells, Cultured | Inflammation Mediators - blood | Neutrophils - immunology | Interleukin-1beta - immunology | DNA - metabolism | Electron Transport Complex IV - genetics | Reverse Transcriptase Polymerase Chain Reaction | Tumor Necrosis Factor-alpha - pharmacology | Aged | Peroxidase - blood | Interleukin-8 - immunology | Cytokines - pharmacology | Peroxidase - metabolism | Oxidases | Viral antibodies | Medicine, Experimental | Antibodies | Medical research | Cytokines | Reactive oxygen species | Phagosomes | Inflammatory response | NAD(P)H oxidase | Blood | Microorganisms | Systemic inflammatory response syndrome | Consent | Gangrene | Tumor necrosis factor-TNF | Peroxidase | Interleukin 8 | Deoxyribonucleic acid--DNA | Killing | Oxygen | Free radicals | Incubation | Neutrophils | Leukocytes (neutrophilic) | Pharmacology | Tumor necrosis factor-α | Gene expression | Patients | Trauma | Augmentation | Preeclampsia | Sepsis | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2014, Volume 41, Issue 3, pp. 478 - 492
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1335 - 1349
... autoantibody generation, that modulate lesion formation (4). Many of these responses are adaptive in nature, responding to the myriad of new moieties generated in response... 
ATHEROSCLEROTIC LESIONS | MEDICINE, RESEARCH & EXPERIMENTAL | STREPTOCOCCUS-PNEUMONIAE | B-CELL LINEAGES | LIPID-PEROXIDATION PRODUCTS | LINKED-IMMUNOSORBENT-ASSAY | APOPTOTIC CELLS | IN-VIVO | MONOCLONAL AUTOANTIBODIES | LOW-DENSITY-LIPOPROTEIN | OXIDIZED PHOSPHOLIPIDS | Germ-Free Life - immunology | B-Lymphocyte Subsets - transplantation | Antibody Affinity - immunology | Male | Adoptive Transfer | Phosphorylcholine - analogs & derivatives | Immunoglobulin M - immunology | Epitopes - immunology | Phosphorylcholine - immunology | Antibody Specificity - immunology | B-Lymphocyte Subsets - immunology | Female | Fetal Blood - immunology | Receptors, LDL - genetics | Antibody Formation - immunology | Atherosclerosis - pathology | Atherosclerosis - immunology | Oxidation-Reduction | Serum Albumin, Bovine - immunology | Malondialdehyde - analogs & derivatives | Mice, Inbred C57BL | Phagocytosis - immunology | Macrophages, Peritoneal - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Immunity, Innate - immunology | Animals | Apoptosis - immunology | Immunoglobulin M - blood | Malondialdehyde - immunology | Mice | Lipoproteins, LDL - immunology | Proteolipids | Oxidative stress | Care and treatment | Lipoproteins | Hypercholesterolemia | Atherosclerosis | Physiological aspects | Genetic aspects | Research | Blood lipoproteins | Risk factors | Immunoglobulin M | Peritoneal | Antibody Specificity | pathology | Mikrobiologi inom det medicinska området | Macrophages | Immunity | B-Lymphocyte Subsets | Receptors | genetics | LDL | immunology | Bovine | Antibody Affinity | Epitopes | Phosphorylcholine | blood | Malondialdehyde | Inbred C57BL | Knockout | Serum Albumin | Microbiology in the medical area | Homeodomain Proteins | analogs & derivatives | transplantation | Germ-Free Life | Antibody Formation | Innate | Fetal Blood | Phagocytosis | Apoptosis
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 470, Issue 7335, pp. 543 - 547
Many successful vaccines induce persistent antibody responses that can last a lifetime. The mechanisms by which they do so remain unclear, but emerging... 
MEMORY B-CELLS | YELLOW-FEVER VACCINE | MULTIDISCIPLINARY SCIENCES | DERMAL DENDRITIC CELLS | IN-VIVO | TOLL-LIKE RECEPTORS | GERMINAL CENTER | EXPRESSION | T-CELLS | LANGERHANS CELLS | ANTIGEN | Influenza A Virus, H1N1 Subtype - immunology | Influenza Vaccines - administration & dosage | Dendritic Cells - immunology | Macaca mulatta - immunology | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Macaca mulatta - virology | Antibodies, Neutralizing - immunology | Plasma Cells - metabolism | Toll-Like Receptors - metabolism | Immunologic Memory - immunology | Antibodies, Viral - biosynthesis | Antibody Formation - immunology | Lactic Acid | Lymphocyte Activation | Mice, Inbred C57BL | Polyglycolic Acid | Toll-Like Receptors - immunology | Lymph Nodes - immunology | Lymph Nodes - cytology | Immunity, Innate - immunology | Animals | Influenza Vaccines - immunology | Antibodies, Neutralizing - biosynthesis | Influenza A Virus, H5N1 Subtype - immunology | Antibodies, Viral - immunology | Ligands | T-Lymphocytes - immunology | Dendritic Cells - cytology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Plasma Cells - cytology | Plasma Cells - immunology | Viral antibodies | Antibodies | Chemical properties | Research | Immunity | Proteins | Nanoparticles | Plasma | Immunology | Avian flu | Immune system
Journal Article
Blood, ISSN 1528-0020, 2012, Volume 119, Issue 6, pp. 1570 - 1580
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2008, Volume 205, Issue 7, pp. 1621 - 1634
Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b− and... 
MEDICINE, RESEARCH & EXPERIMENTAL | IIFN-PRODUCING CELLS | INHALED ANTIGEN | IN-VIVO DEPLETION | ANTIGEN PRESENTATION | STEADY-STATE | IMMUNOLOGY | PULMONARY INFECTION | ANTIBODY-RESPONSE | CD8(+) T-CELLS | RESPIRATORY SYNCYTIAL VIRUS | LANGERHANS CELLS | Dendritic Cells - immunology | Lectins, C-Type - immunology | Male | Lectins, C-Type - genetics | CD11c Antigen - immunology | Trachea - virology | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | CD11b Antigen - genetics | Lung - virology | CD11c Antigen - genetics | Female | CD4-Positive T-Lymphocytes - virology | Dendritic Cells - virology | CD11b Antigen - immunology | Plasma Cells - virology | Antigens, Surface - genetics | Intercellular Signaling Peptides and Proteins - genetics | Antigen Presentation - genetics | Mice, Transgenic | Lymph Nodes - virology | Lymph Nodes - immunology | CD8 Antigens - immunology | Trachea - immunology | Heparin-binding EGF-like Growth Factor | Animals | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - immunology | CD8-Positive T-Lymphocytes - virology | CD8 Antigens - genetics | Dogs | Antibodies, Viral - immunology | Nucleocapsid Proteins - immunology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Antigens, Surface - immunology | Antibody Formation - genetics | Intercellular Signaling Peptides and Proteins - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Plasma Cells - immunology
Journal Article