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1. Full Text CD14+ monocyte‐derived galectin‐9 induces natural killer cell cytotoxicity in chronic hepatitis C
by Nishio, Akira and Tatsumi, Tomohide and Nawa, Takatoshi and Suda, Takahiro and Yoshioka, Teppei and Onishi, Yoshiki and Aono, Satoshi and Shigekawa, Minoru and Hikita, Hayato and Sakamori, Ryotaro and Okuzaki, Daisuke and Fukuhara, Takasuke and Matsuura, Yoshiharu and Hiramatsu, Naoki and Takehara, Tetsuo
Hepatology (Baltimore, Md.), ISSN 0270-9139, 01/2017, Volume 65, Issue 1, pp. 18 - 31
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Antibody-Dependent Cell Cytotoxicity | Lymphocyte Activation | Humans | Middle Aged | Male | Monocytes - immunology | Killer Cells, Natural - physiology | Lipopolysaccharide Receptors | Galectins - physiology | Hepatitis C, Chronic - immunology | Aged, 80 and over | Adult | Female | Aged | Alanine | Liver | Chronic infection | Cytotoxicity | Leukocytes (mononuclear) | Infections | T cell receptors | Lymphocytes T | Hepatoma | CD14 antigen | Galectin-9 | Hepatitis | Monocytes | Cell activation | Clonal deletion | Hepatocytes | Persistent infection | Alanine transaminase | Peripheral blood mononuclear cells | Natural killer cells | Hepatitis C | Phosphatidylserine | Apoptosis | Index Medicus
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2. Full Text Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity
by Kohrt, Holbrook E and Sagiv-Barfi, Idit and Rafiq, Sarwish and Herman, Sarah E. M and Butchar, Jonathon P and Cheney, Carolyn and Zhang, Xiaoli and Buggy, Joseph J and Muthusamy, Natarajan and Levy, Ronald and Johnson, Amy J and Byrd, John C
Blood, ISSN 0006-4971, 03/2014, Volume 123, Issue 12, pp. 1957 - 1960
Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Line | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Pyrimidines - administration & dosage | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Rituximab | Pyrazoles - administration & dosage | Animals | Drug Interactions | Agammaglobulinaemia Tyrosine Kinase | Lymphoma, B-Cell - immunology | Pyrimidines - adverse effects | Cell Line, Tumor | Killer Cells, Natural - immunology | Killer Cells, Natural - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Killer Cells, Natural - metabolism | Antibody-Dependent Cell Cytotoxicity - drug effects | Lymphoma, B-Cell - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Pyrazoles - adverse effects | Index Medicus | Abridged Index Medicus | 12 | Correspondence | 39
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3. Full Text NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
by Wang, Wei and Erbe, Amy K and Hank, Jacquelyn A and Morris, Zachary S and Sondel, Paul M
Frontiers in immunology, ISSN 1664-3224, 2015, Volume 6, pp. 368 - 368
Natural killer cell | Therapeutic monoclonal antibody | Antibody-dependent cellular cytotoxicity | Immunotherapy | Cancer | Natural Killer cell
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4. Full Text Lenalidomide Enhances Natural Killer Cell and Monocyte-Mediated Antibody-Dependent Cellular Cytotoxicity of Rituximab-Treated CD20+ Tumor Cells
by Lei Wu and Mary Adams and Troy Carter and Roger Chen and George Muller and David Stirling and Peter Schafer and J. Blake Bartlett
Clinical cancer research, ISSN 1078-0432, 07/2008, Volume 14, Issue 14, pp. 4650 - 4657
monoclonal anitbodies | antibody-dependent cellular cytotoxicity | lenalidomide | natural killer cell | non-Hodgkin's lymphoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Antibodies, Monoclonal, Murine-Derived | Antibodies, Monoclonal - pharmacology | Humans | Rituximab | Monocytes - immunology | Antigens, CD20 - metabolism | Thalidomide - pharmacology | Blotting, Western | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Monocytes - drug effects | Thalidomide - analogs & derivatives | Flow Cytometry | Hematologic Neoplasms - drug therapy | Killer Cells, Natural - immunology | Killer Cells, Natural - drug effects | Hematologic Neoplasms - immunology | Antibody-Dependent Cell Cytotoxicity - drug effects | Index Medicus
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5. Full Text MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
by Kolbeck, Roland, PhD and Kozhich, Alexander, PhD and Koike, Masamichi, PhD and Peng, Li, PhD and Andersson, Cecilia K., PhD and Damschroder, Melissa M., BA and Reed, Jennifer L., PhD and Woods, Robert, MS and Dall'Acqua, William W., PhD and Stephens, Geoffrey L., PhD and Erjefalt, Jonas S., PhD and Bjermer, Leif, MD and Humbles, Alison A., PhD and Gossage, David, MD and Wu, Herren, PhD and Kiener, Peter A., PhD and Spitalny, George L., PhD and Mackay, Charles R., PhD and Molfino, Nestor A., MD and Coyle, Anthony J., PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2010, Volume 125, Issue 6, pp. 1344 - 1353.e2
Allergy and Immunology | antibody-dependent cell-mediated cytotoxicity | IL-5 | FcγRIIIα | basophil | eosinophil | monoclonal antibody | Asthma | IL-5 receptor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Biological and medical sciences | Medical sciences | Chronic obstructive pulmonary disease, asthma | Pneumology | Recombinant Fusion Proteins - immunology | Surface Plasmon Resonance | Epitope Mapping | Eosinophils - metabolism | Epitopes - metabolism | Eosinophils - drug effects | Interleukin-5 Receptor alpha Subunit - immunology | Cell Count | Humans | Antibodies, Monoclonal - adverse effects | Macaca fascicularis | Interleukin-5 Receptor alpha Subunit - metabolism | Male | Recombinant Fusion Proteins - metabolism | Receptors, IgG - metabolism | Protein Engineering | Female | Eosinophils - pathology | Mutagenesis, Site-Directed | Antibody-Dependent Cell Cytotoxicity | Interleukin-5 Receptor alpha Subunit - genetics | Antibody Affinity | Animals | Antibodies, Monoclonal - administration & dosage | Recombinant Fusion Proteins - genetics | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | gamma RIII alpha | Lungmedicin och allergi | Respiratory Medicine and Allergy
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6. Full Text Antibody‐dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells
by Ochoa, Maria Carmen and Minute, Luna and Rodriguez, Inmaculada and Garasa, Saray and Perez‐Ruiz, Elisabeth and Inogés, Susana and Melero, Ignacio and Berraondo, Pedro
Immunology and cell biology, ISSN 0818-9641, 04/2017, Volume 95, Issue 4, pp. 347 - 355
Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Macrophages - physiology | Killer Cells, Natural - transplantation | Immunotherapy, Adoptive - methods | Antibody-Dependent Cell Cytotoxicity | Cytokines - metabolism | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Antigens, Neoplasm - immunology | Humans | Antibody Affinity | Molecular Targeted Therapy | Receptors, IgG - metabolism | Neoplasms - therapy | Animals | Neoplasms - immunology | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Toll-Like Receptors - metabolism | Index Medicus
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7. Full Text Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies — Impact of effector cells
by Chung, Shan and Lin, Yuwen L and Reed, Chae and Ng, Carl and Cheng, Zhijie Jey and Malavasi, Fabio and Yang, Jihong and Quarmby, Valerie and Song, An
Journal of immunological methods, ISSN 0022-1759, 05/2014, Volume 407, pp. 63 - 75
Glycosylation | Monoclonal antibody | Afucosylated antibody | CD16a | ADCC assay | Antibody-dependent cell-mediated cytotoxicity | Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Cell Line | Immunotherapy, Adoptive - methods | Reproducibility of Results | Antibodies, Monoclonal, Humanized - therapeutic use | Antibody-Dependent Cell Cytotoxicity | Humans | Transgenes - genetics | Immunoglobulin G - therapeutic use | Immunoglobulin Allotypes - immunology | Receptors, IgG - metabolism | Immunoglobulin G - immunology | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Cytotoxicity Tests, Immunologic - methods | Antibodies, Monoclonal, Humanized - immunology | Health aspects | Immunoglobulin G | Biopharmaceutics | Index Medicus
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8. Full Text Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity
by Moessner, Ekkehard and Bruenker, Peter and Moser, Samuel and Puentener, Ursula and Schmidt, Carla and Herter, Sylvia and Grau, Roger and Gerdes, Christian and Nopora, Adam and van Puijenbroek, Erwin and Ferrara, Claudia and Sondermann, Peter and Jaeger, Christiane and Strein, Pamela and Fertig, Georg and Friess, Thomas and Schuell, Christine and Bauer, Sabine and Dal Porto, Joseph and Del Nagro, Christopher and Dabbagh, Karim and Dyer, Martin J. S and Poppema, Sibrand and Klein, Christian and Umana, Pablo
Blood, ISSN 0006-4971, 06/2010, Volume 115, Issue 22, pp. 4393 - 4402
COMPLEMENT | RITUXIMAB | IN-VIVO | LIPID RAFTS | CHRONIC LYMPHOCYTIC-LEUKEMIA | NON-HODGKINS-LYMPHOMA | MONOCLONAL-ANTIBODY | FOLLICULAR LYMPHOMA | C-RECEPTOR POLYMORPHISMS | UMCG Approved | FULLY HUMAN | Life Sciences & Biomedicine | Hematology | Science & Technology | Immunotherapy | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Antineoplastic agents | Tumors | Lymphoma, Non-Hodgkin - immunology | Neoplasm Transplantation | Humans | Lymphoma, B-Cell - therapy | Macaca fascicularis | Transplantation, Heterologous | Antibodies, Monoclonal, Humanized | Lymphoma, B-Cell - immunology | Protein Engineering | Female | Antibodies, Monoclonal - immunology | Antigens, CD20 - immunology | Antibodies, Monoclonal, Murine-Derived | Antibody-Dependent Cell Cytotoxicity | Antibodies, Monoclonal - pharmacology | Rituximab | Receptors, IgG - immunology | Mice, SCID | Antibodies, Monoclonal - genetics | Animals | B-Lymphocytes - immunology | Lymphoma, Non-Hodgkin - therapy | Cell Line, Tumor | Immunoglobulin Variable Region - genetics | Mice | In Vitro Techniques | Immunity, Cellular | Immunoglobulin Fc Fragments - genetics | Lymphocyte Depletion - methods | Cytotoxicity, Immunologic | Index Medicus | Abridged Index Medicus | Immunobiology
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9. Full Text Antibody-dependent cellular cytotoxicity activity of a Novel Anti-PD-L1 antibody avelumab (MSB0010718C) on human tumor cells
by Boyerinas, Benjamin and Jochems, Caroline and Fantini, Massimo and Heery, Christopher R and Gulley, James L and Tsang, Kwong Yok and Schlom, Jeffrey
Cancer immunology research, ISSN 2326-6066, 10/2015, Volume 3, Issue 10, pp. 1148 - 1157
Oncology | Immunology | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Leukocytes, Mononuclear - metabolism | Humans | Antibody-Dependent Cell Cytotoxicity - immunology | Interferon-gamma - metabolism | Biomarkers, Tumor | Receptors, IgG - genetics | Neoplasms - genetics | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Antineoplastic Agents - pharmacology | Cell Membrane - metabolism | Interleukin-12 - pharmacology | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | Antibody-Dependent Cell Cytotoxicity - genetics | Leukocytes, Mononuclear - drug effects | Antibodies, Monoclonal - pharmacology | Genotype | B7-H1 Antigen - genetics | B7-H1 Antigen - metabolism | B7-H1 Antigen - antagonists & inhibitors | T-Lymphocytes, Cytotoxic - metabolism | Neoplasms - immunology | Cell Line, Tumor | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Antibody-Dependent Cell Cytotoxicity - drug effects | Interferon-gamma - pharmacology | Index Medicus | anti-PD-L1 | antibody-dependent cellular cytotoxicity | checkpoint inhibitor
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10. Full Text Activity of lenalidomide in mantle cell lymphoma can be explained by NK cell‐mediated cytotoxicity
by Hagner, Patrick R and Chiu, Hsiling and Ortiz, Maria and Apollonio, Benedetta and Wang, Maria and Couto, Suzana and Waldman, Michelle F and Flynt, Erin and Ramsay, Alan G and Trotter, Matthew and Gandhi, Anita K and Chopra, Rajesh and Thakurta, Anjan
British journal of haematology, ISSN 0007-1048, 11/2017, Volume 179, Issue 3, pp. 399 - 409
immunomodulation | mantle cell lymphoma | antibody‐dependent cell‐mediated cytotoxicity | lenalidomide | natural killer cell | antibody-dependent cell-mediated cytotoxicity | Life Sciences & Biomedicine | Hematology | Science & Technology | Pyrazoles - therapeutic use | Coculture Techniques | Humans | Tumor Microenvironment | Thalidomide - pharmacology | Dose-Response Relationship, Drug | Thalidomide - analogs & derivatives | Killer Cells, Natural - immunology | Tumor Cells, Cultured | Cytotoxicity, Immunologic - drug effects | Lymphoma, Mantle-Cell - genetics | Lymphoma, Mantle-Cell - metabolism | Peptide Hydrolases - metabolism | Pyrazoles - pharmacology | Lenalidomide | Pyrimidines - administration & dosage | Immunologic Factors - administration & dosage | Lymphoma, Mantle-Cell - drug therapy | Treatment Outcome | Pyrimidines - pharmacology | Thalidomide - administration & dosage | Ubiquitin-Protein Ligases | Adaptor Proteins, Signal Transducing | Pyrazoles - administration & dosage | Pyrimidines - therapeutic use | Lymphoma, Mantle-Cell - immunology | Lymphocyte Count | Killer Cells, Natural - drug effects | Mutation | Thalidomide - therapeutic use | Immunologic Factors - pharmacology | Immunologic Factors - therapeutic use | Viral antibodies | Tyrosine | Killer cells | Gene mutations | Analysis | Antibodies | Lymphomas | Immunomodulation | Toxicity | Cytotoxicity | Immunological synapses | Kinases | Survival | Patients | Lymphoma | Granzyme B | Immunology | Lymphocytes | Mantle cell lymphoma | Natural killer cells | Mantle | Protein-tyrosine kinase | Tumors | Index Medicus
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