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British Journal of Cancer, ISSN 0007-0920, 02/2016, Volume 114, Issue 4, pp. 362 - 367
Journal Article
2015, AAPS Advances in the Pharmaceutical Sciences Series, ISBN 9783319130804, Volume 17
Web Resource
2015, AAPS Advances in the Pharmaceutical Sciences Series, ISBN 9783319130804, Volume 17
Web Resource
Nature Reviews Drug Discovery, ISSN 1474-1776, 05/2017, Volume 16, Issue 5, pp. 315 - 337
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 01/2017, Volume 56, Issue 2, pp. 462 - 488
The pyrrolo[2,1‐c][1,4]benzodiazepines (PBDs) are a family of sequence‐selective DNA minor‐groove binding agents that form a covalent aminal bond between their... 
pyrrolobenzodiazepines | antibody–drug conjugates | DNA | interstrand cross-linking | antitumor agents | pyrrolobenzodiaze-pines | DNA-BINDING AFFINITY | ADVANCED SOLID TUMORS | TRANSCRIPTION FACTOR INHIBITION | interstrandcross-linking | BRENTUXIMAB VEDOTIN SGN-35 | VIVO ANTITUMOR-ACTIVITY | IN-VITRO CYTOTOXICITY | PBD DIMERS | CHEMISTRY, MULTIDISCIPLINARY | INTERSTRAND CROSS-LINKING | MOLECULAR-DYNAMICS SIMULATIONS | antibody-drug conjugates | SJG-136 NSC-694501 | Benzodiazepines - pharmacology | Leukemia - pathology | Antibiotics, Antineoplastic - pharmacology | Benzodiazepines - chemical synthesis | Antibodies - chemistry | Humans | Ovarian Neoplasms - pathology | Leukemia - drug therapy | Antibodies - pharmacology | Anthramycin - pharmacology | Pyrroles - pharmacology | Anthramycin - chemical synthesis | Pyrroles - chemical synthesis | Antibiotics, Antineoplastic - chemistry | Antibiotics, Antineoplastic - chemical synthesis | Benzodiazepines - chemistry | Pyrroles - chemistry | Female | Cell Proliferation - drug effects | Molecular Structure | Anthramycin - chemistry | Ovarian Neoplasms - drug therapy | Clinical trials | Pharmaceutical industry | Medical research | Conjugates | Ovarian carcinoma | Molecular structure | Nucleotide sequence | Leukemia | Antibodies | Anthramycin | Benzodiazepines | Guanine | Ovarian cancer | Maps | Natural products | Dimers | Deoxyribonucleic acid--DNA | Payloads | Cancer | Reviews | Review
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