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2008, ISBN 9780123694485, xv, 473 p., [27] p. of plates
The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes... 
Antineoplastic agents | Clinical & internal medicine | Design | Development
Book
Anti-cancer drug design, ISSN 0266-9536, 1985
Journal
2004, 2nd ed., ISBN 1588292282, xiv, 450
Book
2004, ISBN 9780471432029, 362
Molecular Cancer Therapeutics covers state-of-the-art strategies to identify and develop cancer drug target molecules and lead inhibitors for clinical testing.... 
Design | Chemotherapy | Antineoplastic agents | Immunotherapy | Cancer | Cancer - Immunotherapy
eBook
2004, ISBN 9780471444602, xi, 474 p., [8] p. of plates
Book
2008, 1. Aufl., Cancer drug discovery and development series, ISBN 1934115290, xxi, 419
Book
Journal of Controlled Release, ISSN 0168-3659, 08/2016, Volume 235, pp. 182 - 194
A pH-sensitive prodrug, TPGS-CH -DOX, was introduced by conjugating anticancer drug, doxorubicin (DOX), onto -α-tocopherol polyethylene glycol 1000 succinate... 
pH-sensitive | Prodrug | Targeting | Drug resistance | D-α-tocopherol polyethylene glycol 1000 succinate | LIPID NANOPARTICLES | DRUG-DELIVERY | D-alpha-tocopherol polyethylene glycol 1000 succinate | ANTICANCER DRUG | CHEMISTRY, MULTIDISCIPLINARY | TPGS | BREAST-CANCER | IN-VIVO | PHARMACOLOGY & PHARMACY | ACCUMULATION | PHASE-I | CELL | Prodrugs - administration & dosage | Doxorubicin - therapeutic use | Apoptosis - drug effects | Drug Resistance, Multiple - drug effects | Humans | Male | Doxorubicin - chemistry | Prodrugs - chemistry | Drug Delivery Systems | Antibiotics, Antineoplastic - chemistry | MCF-7 Cells | Micelles | Vitamin E - therapeutic use | Female | Vitamin E - chemistry | Doxorubicin - administration & dosage | Cell Survival - drug effects | Mice, Inbred C57BL | Rats, Sprague-Dawley | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Animals | Antibiotics, Antineoplastic - therapeutic use | Tumor Burden - drug effects | Vitamin E - administration & dosage | Drug Liberation | Prodrugs - therapeutic use | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Drug resistance in microorganisms | Anthracyclines | Analysis | Tocopherols | Polyols | Integrins | Tumors | Drugs | Schiff bases | Drug delivery systems | Melanoma | Drugstores | Vehicles | Polyethylene glycol | Pharmacy | Cancer
Journal Article
2007, 1. Aufl., Recent results in cancer research, ISBN 354046090X, Volume 176., xiv, 262
From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor... 
Drug targeting | Chemotherapy | Cancer | Medicine & Public Health | Oncology | Cancer Research
Book
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e62082
Some potent chemotherapy drugs including tubulin-binding agents had been developed from nature plants, such as podophyllotoxin and paclitaxel. However, poor... 
MITOSIS | ANTIMITOTIC ACTIVITY | MICROTUBULES | NATURAL-PRODUCTS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | RESISTANCE | TUBULIN | BINDING AGENTS | EXPRESSION | KINASES | Lung Neoplasms - drug therapy | Podophyllotoxin - pharmacology | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | Endoplasmic Reticulum Stress - genetics | Microtubules - metabolism | Podophyllotoxin - toxicity | Drug Evaluation, Preclinical | Disease Models, Animal | DNA Damage - drug effects | Lung Neoplasms - genetics | M Phase Cell Cycle Checkpoints - drug effects | Endoplasmic Reticulum Stress - drug effects | Antineoplastic Agents, Phytogenic - toxicity | Xenograft Model Antitumor Assays | Animals | Mitosis - drug effects | Signal Transduction - drug effects | Tumor Burden - drug effects | Cell Cycle Checkpoints - drug effects | Models, Biological | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Protein Multimerization - drug effects | Podophyllotoxin - analogs & derivatives | Chemotherapy | Podophyllotoxin | Analysis | Lung cancer | Polymerization | Stress (Physiology) | Tubulins | Health aspects | Apoptosis | Cancer | Drugs | Flow cytometry | Toxicity | Mitosis | Leukemia | DNA damage | Cytotoxicity | Selectivity | Drug development | Kinases | Cancer therapies | Anticancer properties | Metastases | Proteins | Signal transduction | Tubulin | Paclitaxel | Xenografts | Cell cycle | Inhibition | Stains | Deoxyribonucleic acid--DNA | Stresses | Plants (botany) | Hematology | Injection | Survivin | Tumor cell lines | Gene expression | Stress | Aurora B protein | Signaling | Side effects | Cell lines | Colonization | Deoxyribonucleic acid | DNA
Journal Article