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Trends in Molecular Medicine, ISSN 1471-4914, 2012, Volume 18, Issue 6, pp. 337 - 347
Glucosinolates and isothiocyanates have both been objects of research for more than half a century. Interest in these unique phytochemicals escalated following... 
Pathology | PHENETHYL ISOTHIOCYANATE | MEDICINE, RESEARCH & EXPERIMENTAL | MIGRATION INHIBITORY FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | BENZYL ISOTHIOCYANATE | CRUCIFEROUS VEGETABLES | SULFORAPHANE RESTORES | CELL BIOLOGY | TRANSCRIPTION FACTOR NRF2 | TRAUMATIC BRAIN-INJURY | INTRACEREBRAL HEMORRHAGE | SPINAL-CORD-INJURY | BROCCOLI SPROUT BEVERAGES | Cardiovascular Diseases - drug therapy | Humans | Isothiocyanates - administration & dosage | Diabetic Nephropathies - drug therapy | Glucosinolates - chemistry | Neuroprotective Agents - pharmacology | Anticarcinogenic Agents - administration & dosage | Isothiocyanates - chemistry | Anti-Bacterial Agents - chemistry | Helicobacter Infections - drug therapy | Models, Animal | Neuroprotective Agents - administration & dosage | Anticarcinogenic Agents - pharmacology | Isothiocyanates - pharmacology | Neuroprotective Agents - chemistry | Cardiotonic Agents - chemistry | Cardiotonic Agents - pharmacology | Animals | Anticarcinogenic Agents - chemistry | Cardiotonic Agents - administration & dosage | Glucosinolates - pharmacology | Central Nervous System - drug effects | Anti-Bacterial Agents - pharmacology | Cell Transformation, Neoplastic - drug effects | Anti-Bacterial Agents - administration & dosage | Glucosinolates - administration & dosage | Skin - drug effects | Proteins | Analysis
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 3, pp. 972 - 977
Metformin, the first-line drug for treating diabetes, inhibits cellular transformation and selectively kills cancer stem cells in breast cancer cell lines. In... 
T lymphocytes | Cell growth | Phosphorylation | Stem cells | Cell lines | Breast cancer | Diabetes | Heterologous transplantation | Tumors | Cancer | Cancer treatment | Cancer prevention | Inflammation | cancer treatment | RESPIRATORY-CHAIN | METABOLIC SYNDROME | ACTIVATION | cancer prevention | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | CYCLE ARREST | DECREASES | CHEMOTHERAPY | BREAST-CANCER | DIABETIC-PATIENTS | inflammation | AMPK | Inflammation - pathology | Neoplastic Stem Cells - drug effects | Humans | NF-kappa B - metabolism | Breast Neoplasms - metabolism | Inflammation - metabolism | Hypoglycemic Agents - administration & dosage | Neoplastic Stem Cells - metabolism | Anticarcinogenic Agents - administration & dosage | Neoplastic Stem Cells - pathology | Female | Stress, Physiological - drug effects | Metformin - administration & dosage | Anticarcinogenic Agents - pharmacology | STAT3 Transcription Factor - metabolism | Doxorubicin - administration & dosage | Cell Line | Metformin - pharmacology | Breast Neoplasms - drug therapy | Cell Transformation, Neoplastic - metabolism | Hypoglycemic Agents - pharmacology | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Feedback, Physiological - drug effects | Inflammation - prevention & control | Mice | Cell Transformation, Neoplastic - drug effects | Cell Transformation, Neoplastic - pathology | Prevention | Cancer cells | Physiological aspects | Dosage and administration | Hypoglycemic agents | Metformin | Research | Cell transformation | Health aspects | Signal transduction | Metabolism | Biological Sciences
Journal Article
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2014, Volume 106, Issue 2, pp. djt431 - djt431
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 371, Issue 1, pp. 48 - 61
Journal Article
Journal Article
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2010, Volume 390, Issue 1, pp. 61 - 69
The potential for colloidal carriers to increase drug bioavailability has spurred a renewed interest in their uptake mechanisms and movement within cells.... 
Nanoparticles | Cell uptake | Cell membrane | Resveratrol | Cell cycle | Nanomedicine | Controlled release | APOPTOSIS | PROTECTION | NLC | DRUG-DELIVERY | EPR | DELIVERY-SYSTEMS | INDUCTION | CANCER | SLN | PHARMACOLOGY & PHARMACY | LEUKEMIA | Stilbenes - administration & dosage | Nanoparticles - chemistry | Humans | Biological Availability | Delayed-Action Preparations - chemistry | Stilbenes - metabolism | Anticarcinogenic Agents - metabolism | Stilbenes - pharmacology | Drug Carriers - chemistry | Anticarcinogenic Agents - pharmacokinetics | Lipids - chemistry | Lecithins - chemistry | Anticarcinogenic Agents - administration & dosage | Delayed-Action Preparations - pharmacology | Metabolism - drug effects | Anticarcinogenic Agents - pharmacology | Poloxamer - chemistry | Drug Carriers - metabolism | Cell Size - drug effects | Keratinocytes - cytology | Static Electricity | Drug Carriers - pharmacology | Necrosis - chemically induced | Cell Shape - drug effects | Particle Size | Delayed-Action Preparations - metabolism | Keratinocytes - drug effects | Keratinocytes - metabolism | Intracellular Space - metabolism | Hydrophobic and Hydrophilic Interactions | Stilbenes - pharmacokinetics | Cell Proliferation - drug effects | Cell Cycle - drug effects | Cell Nucleus - drug effects | Cell Line, Transformed | Microscopy, Fluorescence
Journal Article
Expert Opinion on Drug Delivery, ISSN 1742-5247, 08/2014, Volume 11, Issue 8, pp. 1285 - 1298
Introduction: Natural products have seen a wide range of acceptability for the prevention and treatment of diseases throughout history. Resveratrol, a member... 
stilbene | antioxidant | bioavailability | resveratrol | Bioavailability | Antioxidant | Resveratrol | Stilbene | ANTIOXIDANT ACTIVITY | PHENOLIC-COMPOUNDS | POLYGONUM-CUSPIDATUM | PROTECTS DOPAMINERGIC-NEURONS | IN-VITRO | NITRIC-OXIDE | TRANS-RESVERATROL | PHARMACOLOGY & PHARMACY | RED WINE | HEALTHY-VOLUNTEERS |