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American Journal of Medicine, The, ISSN 0002-9343, 2012, Volume 125, Issue 9, pp. 882 - 887.e1
Abstract Objective Combination therapy, specifically with aspirin, cholesterol and blood pressure-lowering drugs, substantially reduces the risk of coronary... 
Internal Medicine | Adherence | Prevention | Cardiovascular disease | PERSISTENCE | ACUTE CORONARY SYNDROMES | CONVERTING ENZYME-INHIBITORS | SECONDARY PREVENTION | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | STATIN THERAPY | ACUTE MYOCARDIAL-INFARCTION | BETA-BLOCKERS | MEDICATION ADHERENCE | ARTERY-DISEASE | Drug Costs | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Medication Adherence - statistics & numerical data | Cardiovascular Agents - administration & dosage | Age Factors | Drug Administration Schedule | Cardiovascular Diseases - prevention & control | Humans | Antihypertensive Agents - administration & dosage | Secondary Prevention - methods | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Aspirin - administration & dosage | Drug Prescriptions - statistics & numerical data | Self Administration | Time Factors | Anticholesteremic Agents - administration & dosage | Platelet Aggregation Inhibitors - administration & dosage | Calcium Channel Blockers - administration & dosage | Primary Prevention - methods | Sodium Chloride Symporter Inhibitors - administration & dosage | Myocardial Infarction - prevention & control | Adrenergic beta-Antagonists - administration & dosage | Angiotensin Receptor Antagonists - administration & dosage | Research | Patient compliance | Coronary heart disease | Disease prevention | Prescription drugs | Drug therapy | Meta-analysis | Index Medicus | Abridged Index Medicus | Drugs | Myocardial infarction | Aspirin | Side effects | Enzyme inhibitors | Risk reduction | Age | Statins
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2012, Volume 59, Issue 25, pp. 2344 - 2353
Objectives The primary objective of this study was to evaluate the low-density lipoprotein cholesterol (LDL-C)–lowering efficacy of 5 SAR236553/REGN727... 
Cardiovascular | Internal Medicine | statin | low-density lipoprotein cholesterol | safety | apolipoprotein-B | PCSK9 | SAR236553/REGN727 | hypercholesterolemia | CUTANEOUS VASCULITIS | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CHOLESTEROL | CARDIOVASCULAR OUTCOMES | LOW-DENSITY-LIPOPROTEIN | PREVENTION | REDUCTION | DISEASE | 14 RANDOMIZED-TRIALS | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Proprotein Convertases - antagonists & inhibitors | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Hypercholesterolemia - drug therapy | Time Factors | Pyrroles - administration & dosage | Heptanoic Acids - administration & dosage | Adult | Cholesterol, LDL - blood | Female | Hypercholesterolemia - blood | Double-Blind Method | Proprotein Convertases - metabolism | Treatment Outcome | Anticholesteremic Agents - adverse effects | Drug Synergism | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Antibodies, Monoclonal - administration & dosage | Anticholesteremic Agents - administration & dosage | Aged | Serine Endopeptidases - metabolism | Proprotein Convertase 9 | Care and treatment | Serine | Low density lipoproteins | Antibodies | Thrombin | Lipoprotein A | Cholesterol | Cardiovascular agents | Antilipemic agents | Viral antibodies | Complications and side effects | Hypercholesterolemia | Proteases | Monoclonal antibodies | Universities and colleges | Laboratories | Lipids | Triglycerides | Lipoproteins | Pain | Influenza | Patient safety | Population | Mutation | Clinical medicine | Diabetes | Statins | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2015, Volume 100, Issue 8, pp. 3140 - 3148
Journal Article
JAMA, ISSN 0098-7484, 09/2013, Volume 310, Issue 9, pp. 918 - 929
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2017, Volume 376, Issue 15, pp. 1430 - 1440
Journal Article
Journal Article
BMJ: British Medical Journal, ISSN 0959-8138, 6/2013, Volume 346, Issue 7913, pp. 20 - 22
  Now, over two decades later, new guidelines warn against the serious harms of high dose steroids. Doctors who are skeptical about the scientific basis of... 
Neurology | Spinal cord | Physicians | Committees | Standards of care | Strokes | Skepticism | Dosage | Steroids | Polls | FEATURES | STROKE | MEDICINE, GENERAL & INTERNAL | TISSUE-PLASMINOGEN ACTIVATOR | EMERGENCY PHYSICIANS | OF-INTEREST | CLAIMS | THROMBOLYSIS | SPINAL-CORD-INJURY | METHYLPREDNISOLONE | FAILURE | Conflict of Interest - economics | Spinal Cord Injuries - drug therapy | Practice Guidelines as Topic - standards | United States | Bias | Humans | Erythropoietin - adverse effects | Tissue Plasminogen Activator - economics | Periodicals as Topic - standards | Adrenal Cortex Hormones - economics | Tissue Plasminogen Activator - adverse effects | Evidence-Based Medicine - standards | Evidence-Based Medicine - trends | National Institutes of Health (U.S.) | Early Termination of Clinical Trials | Fibrinolytic Agents - adverse effects | Standard of Care - standards | Guideline Adherence - trends | Drug Industry - economics | Evidence-Based Medicine - ethics | Standard of Care - trends | Evidence-Based Medicine - economics | Erythropoietin - administration & dosage | Drug Administration Schedule | Anticholesteremic Agents - economics | Tissue Plasminogen Activator - administration & dosage | Authorship - standards | Stroke - drug therapy | Controlled Clinical Trials as Topic | Erythropoietin - economics | Trust | Anticholesteremic Agents - adverse effects | Societies, Medical - economics | Adrenal Cortex Hormones - adverse effects | Fear | Malpractice - legislation & jurisprudence | Conflict of Interest - legislation & jurisprudence | Fibrinolytic Agents - economics | Anticholesteremic Agents - administration & dosage | Fibrinolytic Agents - administration & dosage | Adrenal Cortex Hormones - administration & dosage | Conflicts of interest | Drug dosages | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 12, pp. 1108 - 1118
A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial... 
POPULATION | MEDICINE, GENERAL & INTERNAL | STATIN | MICE | MUTATIONS | Proprotein Convertases - antagonists & inhibitors | Injections, Intravenous | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Injections, Subcutaneous | Serine Endopeptidases - immunology | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Pyrroles - therapeutic use | Proprotein Convertases - metabolism | Receptors, LDL - metabolism | Lipoproteins - blood | Anticholesteremic Agents - adverse effects | Proprotein Convertases - immunology | Hyperlipoproteinemia Type II - metabolism | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Antibodies, Monoclonal - administration & dosage | Anticholesteremic Agents - administration & dosage | Least-Squares Analysis | Serine Endopeptidases - metabolism | Receptors, LDL - drug effects | Hypercholesterolemia - metabolism | Proprotein Convertase 9 | Drugs | Dose-response relationship (Biochemistry) | Hypercholesterolemia | Monoclonal antibodies | Cholesterol, LDL | Dosage and administration | Product/Service Evaluations | Research | Drug therapy | Health aspects | Studies | Lipoproteins (low density) | Kexin | Serine | Atorvastatin | Cardiovascular disease | Subtilisin | Low density lipoprotein | Cholesterol | Index Medicus | Abridged Index Medicus
Journal Article
JAMA, ISSN 0098-7484, 05/2014, Volume 311, Issue 18, pp. 1870 - 1882
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9753, pp. 1658 - 1669
Journal Article