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Current medical research and opinion, ISSN 1473-4877, 2012, Volume 29, Issue 1, pp. 1 - 12
...-related protease inhibitors. Rifabutin reduces serum concentrations of antiretroviral agents, but less so than rifampin... 
Rifabutin | Rifampin | Rifapentine | Drug interactions | MEDICINE, RESEARCH & EXPERIMENTAL | ENZYME-INDUCTION | PLATELET-AGGREGATION | ATORVASTATIN | SINGLE-BLIND | MEDICINE, GENERAL & INTERNAL | CLOPIDOGREL | PHARMACOKINETICS | METABOLISM | PLASMA-CONCENTRATIONS | HEALTHY-VOLUNTEERS | TRANSPORTER INHIBITION | Rifampin - analogs & derivatives | Simvastatin - therapeutic use | Antifungal Agents - adverse effects | Digoxin - adverse effects | Simvastatin - adverse effects | Antibiotics, Antitubercular - adverse effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antifungal Agents - therapeutic use | Rifampin - adverse effects | Verapamil - therapeutic use | Drug Interactions | Verapamil - adverse effects | Rifampin - therapeutic use | Contraceptives, Oral - adverse effects | Contraceptives, Oral - therapeutic use | Digoxin - therapeutic use | HIV Protease Inhibitors - adverse effects | Rifabutin - adverse effects | Anti-Arrhythmia Agents - therapeutic use | HIV Protease Inhibitors - therapeutic use | Anticholesteremic Agents - adverse effects | Itraconazole - therapeutic use | Anticholesteremic Agents - therapeutic use | Anti-Arrhythmia Agents - adverse effects | Itraconazole - adverse effects | Antibiotics, Antitubercular - therapeutic use | Cytochrome P-450 Enzyme System - biosynthesis | Rifabutin - therapeutic use | ATP Binding Cassette Transporter, Sub-Family B | Index Medicus
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 2007, Volume 14, Issue 3, pp. 315 - 338
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0135634
Aim Unlike rats and mice, hamsters develop hypercholesterolemia, and hypertriglyceridemia when fed a cholesterol-rich diet. Because hyperlipidemia is a... 
CHOLESTEROL ABSORPTION | BODY-WEIGHT | TRANSFER PROTEIN | METABOLIC SYNDROME | GLUCAGON-LIKE PEPTIDE-1 | NEUROMEDIN U | FOOD-INTAKE | GLUCOSE | MULTIDISCIPLINARY SCIENCES | IV INHIBITOR | RECEPTOR | Hypoglycemic Agents - therapeutic use | Cricetinae | Obesity - drug therapy | Cholesterol - blood | Diet, High-Fat - adverse effects | Male | Linagliptin - therapeutic use | Obesity - blood | Anti-Obesity Agents - therapeutic use | Neuropeptides - therapeutic use | Blood Glucose - drug effects | Eating - drug effects | Animals | Anticholesteremic Agents - therapeutic use | Mesocricetus | Peptide YY - therapeutic use | Obesity - etiology | Ezetimibe - therapeutic use | Hypolipidemic Agents - therapeutic use | Peptide Fragments - therapeutic use | Low density lipoproteins | Body weight | Glucose | Hamsters | Cholesterol | Dextrose | Antilipemic agents | Hypercholesterolemia | Diet therapy | Diet | Analysis | Blood lipids | Diabetes | Lipoproteins (low density) | Neurosciences | Peptides | Body fat | Lipids | Metabolic syndrome | Rodents | Supplementation | Lipoproteins (high density) | Sugar | Food | Energy intake | Obesity | Evaluation | Peptidase | Hyperlipidemia | Diabetes mellitus | Dietary supplements | Apolipoproteins | Body weight gain | Glucose tolerance | Weight control | Lipoproteins | Inhibitors | Food intake | Hypertriglyceridemia | Weight reduction | Food preferences | Insulin resistance | Laboratory animals | Endocrinology | Neuromedin
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 05/2017, Volume 317, Issue 17, pp. 1785 - 1795
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 1532-6535, 2007, Volume 82, Issue 1, pp. 21 - 32
The low productivity and escalating costs of drug development have been well documented over the past several years. Less than 10% of new compounds that enter... 
TRIPTANS SEROTONIN | METAANALYSIS | DOSE-RESPONSE | INTEGRATION | 5-HT1B/1D AGONISTS | PHARMACOLOGY & PHARMACY | SIMULATION | MIGRAINE | Analgesics - pharmacology | Muscarinic Agonists - pharmacology | Cholesterol - blood | Humans | Glycoproteins - pharmacology | Caproates - therapeutic use | Amines - therapeutic use | Alzheimer Disease - psychology | Neutrophil Infiltration - drug effects | United States Food and Drug Administration | Glycoproteins - therapeutic use | Alzheimer Disease - drug therapy | gamma-Aminobutyric Acid - pharmacology | Stroke - drug therapy | Cognition - drug effects | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Models, Biological | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Amines - pharmacology | Immunologic Factors - pharmacology | Clinical Trials as Topic - legislation & jurisprudence | Guidelines as Topic | Meta-Analysis as Topic | Clinical Trials as Topic - statistics & numerical data | United States | Caproates - pharmacology | Muscarinic Agonists - therapeutic use | Oximes - therapeutic use | Drug Approval | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Computer Simulation | Drug Design | gamma-Aminobutyric Acid - therapeutic use | Stroke - immunology | Analgesics - therapeutic use | Cyclohexanecarboxylic Acids - therapeutic use | Hypercholesterolemia - blood | Reproducibility of Results | Neuralgia, Postherpetic - drug therapy | Pharmacology | Models, Statistical | Animals | Anticholesteremic Agents - therapeutic use | Cyclohexanecarboxylic Acids - pharmacology | Oximes - pharmacology | Clinical Trials as Topic - methods | Pharmacokinetics | Research Design | Anticholesteremic Agents - pharmacology | Immunologic Factors - therapeutic use
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 378, Issue 9786, pp. 182 - 197
.... Novel approaches to glycaemic regulation include use of inhibitors of the sodium–glucose cotransporter 2, which increase renal glucose elimination, and inhibitors of 11β... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | DIPEPTIDYL PEPTIDASE-4 INHIBITOR | GLUCAGON-LIKE PEPTIDE-1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1 | ALPHA-CELL DYSFUNCTION | SMALL-MOLECULE | INSULIN-RESISTANCE | DOUBLE-BLIND | BARIATRIC SURGERY | BETA-CELL | INADEQUATE GLYCEMIC CONTROL | Glucokinase - physiology | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Allylamine - therapeutic use | Liver - physiopathology | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Peptides - administration & dosage | Hypoglycemic Agents - administration & dosage | Liver - drug effects | Insulin Resistance - physiology | Allylamine - pharmacology | Receptors, Dopamine D2 - drug effects | Glucagon-Like Peptide 1 - analysis | Venoms - administration & dosage | Indoles - pharmacology | Hyperglycemia - physiopathology | Colesevelam Hydrochloride | Bariatric Surgery | Hypoglycemic Agents - therapeutic use | Insulin-Secreting Cells - physiology | Obesity - surgery | Insulin - pharmacology | Comorbidity | Receptors, Dopamine D2 - agonists | Allylamine - analogs & derivatives | Treatment Outcome | Cardiovascular System - drug effects | 11-beta-Hydroxysteroid Dehydrogenase Type 1 - antagonists & inhibitors | Bile Acids and Salts | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | Randomized Controlled Trials as Topic | Anticholesteremic Agents - therapeutic use | Diabetes Mellitus, Type 2 - physiopathology | Insulin-Secreting Cells - drug effects | Signal Transduction - drug effects | Obesity - epidemiology | Indoles - therapeutic use | Signal Transduction - physiology | Diabetes Mellitus, Type 2 - drug therapy | Anticholesteremic Agents - pharmacology | Type 2 diabetes | Technology application | Care and treatment | Therapeutics | Diagnosis | Research | Homeopathy | Materia medica and therapeutics | Obesity | Medical research | Insulin resistance | Diabetes | Insulin
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2014, Volume 370, Issue 1, pp. 13 - 22
In this trial, 947 patients with renal-artery stenosis were assigned to renal-artery stenting or medical therapy. At a median of 43 months, there was no... 
MEDICINE, GENERAL & INTERNAL | REVASCULARIZATION | SYSTOLIC BLOOD-PRESSURE | PLACEMENT | PREVENTION | BALLOON ANGIOPLASTY | PREVALENCE | HYPERTENSION | Follow-Up Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Male | Renal Insufficiency, Chronic - complications | Renal Artery | Treatment Failure | Cardiovascular Diseases - mortality | Female | Angioplasty, Balloon | Pyrroles - therapeutic use | Stents | Cardiovascular Diseases - etiology | Renal Artery Obstruction - drug therapy | Kaplan-Meier Estimate | Combined Modality Therapy | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Renal Artery Obstruction - complications | Anticholesteremic Agents - therapeutic use | Hypertension - complications | Aged | Renal Artery Obstruction - therapy | Drug Combinations | Prevention | Evaluation | Care and treatment | Usage | Atherosclerosis | Therapeutics | Stent (Surgery) | Homeopathy | Materia medica and therapeutics | Hypertension | Myocardial infarction | Cerebral infarction | Stroke | Kidneys | Renal artery | Antihypertensives | Medical treatment | Clinical trials | Stenosis | Cardiovascular disease | Congestive heart failure | Renal insufficiency | Arteriosclerosis | Implants | Renal failure | Blood pressure | Kidney diseases | Geriatrics
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2011, Volume 365, Issue 22, pp. 2078 - 2087
In this trial, intravascular ultrasonography was used to compare the effects of atorvastatin versus rosuvastatin on regression of coronary atherosclerosis.... 
MEDICINE, GENERAL & INTERNAL | EVENTS | MYOCARDIAL-INFARCTION | CHOLESTEROL | EFFICACY | ATHEROSCLEROSIS | PREVENTION | INTRAVASCULAR ULTRASOUND | PRAVASTATIN | ROSUVASTATIN | ATORVASTATIN | Coronary Vessels - diagnostic imaging | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Ultrasonography, Interventional | Male | Heptanoic Acids - adverse effects | Coronary Artery Disease - pathology | Pyrroles - adverse effects | Cholesterol, LDL - blood | Female | Pyrroles - therapeutic use | Coronary Vessels - pathology | Double-Blind Method | Rosuvastatin Calcium | Coronary Artery Disease - drug therapy | Anticholesteremic Agents - adverse effects | Disease Progression | Atorvastatin Calcium | Coronary Artery Disease - diagnostic imaging | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Cholesterol, HDL - blood | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Fluorobenzenes - therapeutic use | Drugs | Rosuvastatin | Dosage and administration | Product/Service Evaluations | Drug therapy | Atherosclerosis | Lipoproteins (low density) | Clinical trials | Cardiovascular disease | Patients | Cholesterol | Studies | Side effects | Ultrasonic imaging | Arteriosclerosis | Atorvastatin | Heart diseases | Lipoproteins (high density) | Ultrasound | Statins
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 25, pp. 2387 - 2397
Journal Article