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Science, ISSN 0036-8075, 5/2001, Volume 292, Issue 5518, pp. 897 - 902
Crystal structures of the 30S ribosomal subunit in complex with messenger RNA and cognate transfer RNA in the A site, both in the presence and absence of the... 
Messenger RNA | Hydrogen bonds | RNA | Antibiotics | Protein synthesis | Ribosomes | Crystals | Research Articles | Codons | Anticodon | Transfer RNA | P-SITE | ANGSTROM RESOLUTION | ELONGATION-FACTOR TU | ESCHERICHIA-COLI RIBOSOME | AMINOACYL-TRANSFER-RNA | PHENYLALANINE TRANSFER-RNA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | A-SITE | 70S RIBOSOME | DNA-REPLICATION | Codon - metabolism | Anticodon - metabolism | Protein Biosynthesis | Peptide Chain Elongation, Translational | RNA, Transfer, Phe - chemistry | Anticodon - chemistry | RNA, Transfer, Amino Acid-Specific - metabolism | Ribosomes - metabolism | Thermus thermophilus - metabolism | Crystallography, X-Ray | Thermus thermophilus - ultrastructure | Guanosine Triphosphate - metabolism | RNA, Messenger - metabolism | Paromomycin - pharmacology | Thermodynamics | Nucleic Acid Conformation | RNA, Transfer - chemistry | Binding Sites | RNA, Bacterial - metabolism | RNA, Ribosomal, 16S - metabolism | RNA, Transfer, Phe - metabolism | Thermus thermophilus - chemistry | RNA, Transfer - metabolism | Ribosomes - chemistry | Models, Molecular | Anti-Bacterial Agents - metabolism | Peptide Elongation Factor Tu - metabolism | RNA, Transfer, Amino Acid-Specific - chemistry | RNA, Ribosomal, 16S - chemistry | Ribosomes - ultrastructure | Codon - chemistry | Base Pairing | Hydrogen Bonding | RNA, Bacterial - chemistry | RNA, Messenger - chemistry | Anti-Bacterial Agents - pharmacology | Paromomycin - metabolism | Protein research | Usage | Polypeptides | Amino acids | Research | Molecular biology | Statistics | Ribonucleic acid--RNA | Ribonucleic acid | ribosomal subunit 30S | paromomysin | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2006, Volume 313, Issue 5795, pp. 1935 - 1942
The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and... 
Phosphates | Oxygen | Messenger RNA | RNA | Ribosomes | Haloarcula | Research Articles | Nucleotides | Anticodon | Transfer RNA | Metal ions | P-SITE | ANGSTROM RESOLUTION | ATOMIC-STRUCTURE | ESCHERICHIA-COLI RIBOSOME | BACTERIAL RIBOSOME | PHENYLALANINE TRANSFER-RNA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PEPTIDE-BOND FORMATION | 50S SUBUNITS | PROTEIN L27 | Ribosomal Proteins - chemistry | Protein Biosynthesis | RNA, Transfer, Phe - chemistry | Bacterial Proteins - chemistry | Ribosomes - metabolism | Crystallography, X-Ray | Thermus thermophilus - ultrastructure | RNA, Messenger - metabolism | Ribosomal Proteins - metabolism | Codon | Nucleic Acid Conformation | RNA, Transfer - chemistry | RNA, Bacterial - metabolism | RNA, Transfer, Phe - metabolism | Peptidyl Transferases - metabolism | Thermus thermophilus - chemistry | RNA, Transfer - metabolism | Peptidyl Transferases - chemistry | RNA, Transfer, Met - metabolism | Crystallization | Ribosomes - chemistry | Models, Molecular | Magnesium - metabolism | Ribosomes - ultrastructure | RNA, Transfer, Met - chemistry | RNA, Bacterial - chemistry | Bacterial Proteins - metabolism | Protein Conformation | RNA, Messenger - chemistry | Research | Structure | Ribosomal RNA | Analysis | Bacteria | Genetics | Biochemistry | Ribonucleic acid--RNA | Ribonucleic acid | Crystal structure | Index Medicus
Journal Article
Science, ISSN 0036-8075, 8/2009, Volume 325, Issue 5943, pp. 1014 - 1017
Protein biosynthesis on the ribosome requires repeated cycles of ratcheting, which couples rotation of the two ribosomal subunits with respect to each other,... 
Proteins | Head | Messenger RNA | Ribosomes | Reports | Rotational states | Nucleotides | Rotation | Binding sites | Transfer RNA | Crystal structure | ANGSTROM RESOLUTION | COMPLEX | MESSENGER-RNA | TRANSFER-RNA TRANSLOCATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MOVEMENT | HYBRID STATE | TRANSLATION TERMINATION | BINDING | 70S RIBOSOME | Ribosomal Proteins - chemistry | Anticodon - metabolism | Protein Biosynthesis | RNA, Transfer, Phe - chemistry | Ribosome Subunits, Large, Bacterial - metabolism | Anticodon - chemistry | Ribosomes - metabolism | Crystallography, X-Ray | RNA, Messenger - metabolism | Ribosomal Proteins - metabolism | Escherichia coli Proteins - biosynthesis | Escherichia coli - metabolism | Nucleic Acid Conformation | RNA, Bacterial - metabolism | RNA, Transfer, Phe - metabolism | Ribosome Subunits, Small, Bacterial - metabolism | RNA, Transfer, Met - metabolism | Ribosome Subunits, Large, Bacterial - ultrastructure | Ribosomes - chemistry | Escherichia coli Proteins - metabolism | Escherichia coli - chemistry | Ribosome Subunits, Small, Bacterial - ultrastructure | Ribosomes - ultrastructure | RNA, Transfer, Met - chemistry | Ribosome Subunits, Large, Bacterial - chemistry | RNA, Bacterial - chemistry | Protein Conformation | RNA, Messenger - chemistry | Ribosome Subunits, Small, Bacterial - chemistry | Escherichia coli Proteins - chemistry | Escherichia coli - ultrastructure | Escherichia coli | Physiological aspects | Protein biosynthesis | Genetic aspects | Research | Structure | E coli | Molecular biology | Protein synthesis | Anticodons | Index Medicus
Journal Article
Science, ISSN 0036-8075, 5/2011, Volume 332, Issue 6032, pp. 981 - 984
During protein synthesis, the ribosome controls the movement of tRNA and mRNA by means of large-scale structural rearrangements. We describe structures of the... 
Messenger RNA | RNA | REPORTS | Ribosomes | Amino acids | Nucleotides | Recycling | Rotation | Hybridity | Transfer RNA | Crystal structure | TRANSLOCATION | TRANSLATION FACTORS | AMINOACYL-TRANSFER-RNA | MESSENGER-RNA | CRYSTAL-STRUCTURE | INTERMEDIATE STATES | MULTIDISCIPLINARY SCIENCES | DYNAMICS | CRYO-EM | RECYCLING FACTOR | 70S RIBOSOME | Anticodon - metabolism | Protein Biosynthesis | RNA, Transfer, Phe - chemistry | Ribosome Subunits, Large, Bacterial - metabolism | Escherichia coli | RNA, Transfer, Amino Acyl - chemistry | Anticodon - chemistry | Crystallography, X-Ray | RNA, Messenger - metabolism | Ribosomal Proteins - metabolism | RNA, Transfer, Amino Acyl - metabolism | Nucleic Acid Conformation | RNA, Bacterial - metabolism | RNA, Ribosomal, 16S - metabolism | RNA, Transfer, Phe - metabolism | Ribosome Subunits, Small, Bacterial - metabolism | Ribosome Subunits, Large, Bacterial - ultrastructure | Models, Molecular | Escherichia coli Proteins - metabolism | RNA, Ribosomal, 23S - chemistry | Ribosome Subunits, Small, Bacterial - ultrastructure | RNA, Ribosomal, 16S - chemistry | Ribosome Subunits, Large, Bacterial - chemistry | RNA, Bacterial - chemistry | RNA, Messenger - chemistry | Ribosome Subunits, Small, Bacterial - chemistry | RNA, Ribosomal, 23S - metabolism | Physiological aspects | Protein biosynthesis | Properties | E coli | Microbiology | Ribonucleic acid--RNA | Protein synthesis | Binding sites | Index Medicus
Journal Article
Science, ISSN 0036-8075, 3/2012, Volume 335, Issue 6074, pp. 1366 - 1369
In bacteria, ribosomes stalled at the end of truncated messages are rescued by transfer-messenger RNA (tmRNA), a bifunctional molecule that acts as both a... 
Proteins | Messenger RNA | RNA | REPORTS | Ribosomes | Nucleotides | Open reading frames | Codons | Anticodon | Transfer RNA | Crystal structure | AMINOACYL-TRANSFER-RNA | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | TAGGING ACTIVITY | TRANSFER-MESSENGER-RNA | SMALL PROTEIN-B | BINDING PROTEIN | TRANS-TRANSLATION | STALLED RIBOSOMES | Protein Biosynthesis | Bacterial Proteins - chemistry | Molecular Sequence Data | Ribosomes - metabolism | Thermus thermophilus - metabolism | Crystallography, X-Ray | Thermus thermophilus - ultrastructure | RNA, Messenger - metabolism | Thermus thermophilus - genetics | Base Sequence | Nucleic Acid Conformation | RNA, Transfer - chemistry | RNA, Bacterial - metabolism | Ribosome Subunits, Small, Bacterial - metabolism | Thermus thermophilus - chemistry | RNA, Transfer - metabolism | RNA-Binding Proteins - chemistry | Ribosomes - chemistry | Models, Molecular | Peptide Elongation Factor Tu - chemistry | Peptide Elongation Factor Tu - metabolism | Ribosome Subunits, Small, Bacterial - ultrastructure | Ribosomes - ultrastructure | RNA, Bacterial - chemistry | Bacterial Proteins - metabolism | Protein Conformation | RNA, Messenger - chemistry | Ribosome Subunits, Small, Bacterial - chemistry | RNA-Binding Proteins - metabolism | Physiological aspects | Bacteria | Codon | Research | Molecular chemistry | Gram-negative bacteria | Peptides | Ribonucleic acid--RNA | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
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