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Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2012, Volume 20, Issue 11, pp. 3378 - 3395
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 239 - 280
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole ring are readily able to bind with a variety of enzymes and receptors in... 
Triazole | Antifungal | Antidiabetic | Triazolium | Anticonvulsant | Antibacterial | Antihistaminic | Antitubercular | Analgesic | Anti-obesitic | Antiparasitic | Antiviral | Anticancer | Anti-inflammatory | Anti-neuropathic | A ADENOSINE RECEPTOR | analgesic | antibacterial | anticancer | triazole | CLICK CHEMISTRY APPROACH | antihistaminic | ANTIBACTERIAL ACTIVITY | anti-inflammatory | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | anti-neuropathic | CHEMISTRY, MEDICINAL | INOSINE MONOPHOSPHATE DEHYDROGENASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFICIENT SYNTHESIS | PHARMACOLOGICAL IN-VITRO | AZOLE ANTIFUNGAL AGENTS | antitubercular | anti-obesitic | triazolium | antiviral | antiparasitic | antidiabetic | HISTONE DEACETYLASE INHIBITORS | ANTIMICROBIAL ACTIVITY | Antifungal Agents - pharmacology | Analgesics - pharmacology | Antiviral Agents - pharmacology | Antitubercular Agents - chemistry | Anti-Inflammatory Agents - pharmacology | Triazoles - chemistry | Antitubercular Agents - pharmacology | Antifungal Agents - chemistry | Hypoglycemic Agents - chemistry | Antineoplastic Agents - chemistry | Anticonvulsants - pharmacology | Hypoglycemic Agents - pharmacology | Triazoles - pharmacology | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anticonvulsants - chemistry | Antiparasitic Agents - pharmacology | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Antiparasitic Agents - chemistry
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2015, Volume 89, pp. 743 - 816
The biological activity of Mannich bases, a structurally heterogeneous class of chemical compounds that are generated from various substrates through the... 
Aminomethylation | Drug design | Mannich bases | Structure–activity relationships | Biological activity | Structure-activity relationships | Structureeactivity relationships | CHEMISTRY, MEDICINAL | ANTIMICROBIAL ACTIVITY EVALUATION | ONE-POT SYNTHESIS | PURINE NUCLEOSIDE PHOSPHORYLASE | STATE ANALOG INHIBITORS | B VIRUS ACTIVITIES | DOXORUBICIN-FORMALDEHYDE CONJUGATE | REGIOSELECTIVE REACTION SYNTHESIS | TITANOCENE ANTICANCER DRUGS | THYROID-HORMONE RECEPTOR | MYCOBACTERIUM-TUBERCULOSIS ISOCITRATE | Analgesics - pharmacology | Antioxidants - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Anticonvulsants - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Mannich Bases - chemical synthesis | Analgesics - chemical synthesis | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Drug Design | Mannich Bases - pharmacology | Antineoplastic Agents - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Antimalarials - chemical synthesis | Antifungal Agents - pharmacology | Antiviral Agents - pharmacology | Anticonvulsants - chemical synthesis | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Chemistry, Pharmaceutical | Mannich Bases - chemistry | Antimalarials - pharmacology | Anti-Bacterial Agents - chemical synthesis | Animals | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Antiviral Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Antioxidants | Antiviral agents | Enzymes | Mental illness | Bases (Chemistry)
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 11/2013, Volume 128, pp. 85 - 96
Zinc(II) complexes of a non-steroidal anti-inflammatory drug, mefenamic acid(= Hmef) in the absence or presence of the nitrogen donor heterocyclic ligands... 
Antioxidant capacity | Zinc complexes | Interaction with calf-thymus DNA | Mefenamic acid | Interaction with serum albumins | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTICONVULSANT ACTIVITIES | CRYSTAL-STRUCTURES | STRUCTURAL-CHARACTERIZATION | BINDING PROPERTIES | CHEMISTRY, INORGANIC & NUCLEAR | COPPER(II) COMPLEXES | IN-VITRO | BIOLOGICAL EVALUATION | COBALT(II) COMPLEXES | METAL-COMPLEXES | Free Radical Scavengers - pharmacology | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Antioxidants - metabolism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Coordination Complexes - metabolism | Crystallography, X-Ray | Zinc - chemistry | Biphenyl Compounds - metabolism | Mefenamic Acid - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Lipoxygenase - metabolism | Zinc Compounds - metabolism | Biphenyl Compounds - antagonists & inhibitors | Lipoxygenase Inhibitors - chemistry | Zinc Compounds - pharmacology | Cattle | Mefenamic Acid - metabolism | Picrates - chemistry | Soybeans - enzymology | Coordination Complexes - pharmacology | Free Radicals - metabolism | Serum Albumin, Bovine - chemistry | Molecular Structure | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Biphenyl Compounds - chemistry | Serum Albumin - chemistry | Free Radical Scavengers - metabolism | Free Radicals - chemistry | Picrates - metabolism | Antioxidants - pharmacology | DNA - metabolism | Serum Albumin, Bovine - metabolism | Coordination Complexes - chemistry | Spectrophotometry, Ultraviolet | Zinc Compounds - chemistry | DNA - chemistry | Free Radicals - antagonists & inhibitors | Mefenamic Acid - pharmacology | Picrates - antagonists & inhibitors | Animals | Lipoxygenase Inhibitors - metabolism | Kinetics | Lipoxygenase Inhibitors - pharmacology | Serum Albumin - metabolism | Proteins | Antioxidants | Drug interactions | DNA | Genetic research | Nonsteroidal anti-inflammatory drugs | Protein binding
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 8, pp. 3179 - 3189
This review summarizes recent medicinal chemistry investigations and in search for new phenothiazines of promising biological activities. New phenothiazine... 
Multi-drug resistance | Antifungal | Antibacterial | Azaphenothiazines | Anticancer | Phenothiazines | CHEMISTRY, MEDICINAL | MUSTARD TYPE PHENOTHIAZINES | SULFONE DERIVATIVES | ANTITUMOR-ACTIVITY | ANTICANCER ACTIVITY | ANTIMICROBIAL ACTIVITIES | RIBOFURANOSIDES | N-ACYLPHENOTHIAZINES | ANTITUBERCULAR ACTIVITY | INHIBITORS | MULTIDRUG-RESISTANCE | Analgesics - pharmacology | Drug Resistance, Multiple | Humans | Bacteria - drug effects | Cell Membrane Permeability | Trypanocidal Agents - chemistry | Antifungal Agents - chemistry | Structure-Activity Relationship | Anticonvulsants - pharmacology | Antiviral Agents - chemistry | Phenothiazines - pharmacology | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Immunosuppressive Agents - pharmacology | Antifungal Agents - pharmacology | Rabbits | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Solubility | Rats | Viruses - drug effects | Antineoplastic Agents - chemistry | Antimalarials - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Antipsychotic Agents - chemistry | Phenothiazines - chemistry | Trypanocidal Agents - pharmacology | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Mice | Antipsychotic Agents - pharmacology | Immunosuppressive Agents - chemistry
Journal Article
Journal Article