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Current Medicinal Chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 239 - 280
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole ring are readily able to bind with a variety of enzymes and receptors in... 
Triazole | Antifungal | Antidiabetic | Triazolium | Anticonvulsant | Antibacterial | Antihistaminic | Antitubercular | Analgesic | Anti-obesitic | Antiparasitic | Antiviral | Anticancer | Anti-inflammatory | Anti-neuropathic | A ADENOSINE RECEPTOR | analgesic | antibacterial | anticancer | triazole | CLICK CHEMISTRY APPROACH | antihistaminic | ANTIBACTERIAL ACTIVITY | anti-inflammatory | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | anti-neuropathic | CHEMISTRY, MEDICINAL | INOSINE MONOPHOSPHATE DEHYDROGENASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFICIENT SYNTHESIS | PHARMACOLOGICAL IN-VITRO | AZOLE ANTIFUNGAL AGENTS | antitubercular | anti-obesitic | triazolium | antiviral | antiparasitic | antidiabetic | HISTONE DEACETYLASE INHIBITORS | ANTIMICROBIAL ACTIVITY | Antifungal Agents - pharmacology | Analgesics - pharmacology | Antiviral Agents - pharmacology | Antitubercular Agents - chemistry | Anti-Inflammatory Agents - pharmacology | Triazoles - chemistry | Antitubercular Agents - pharmacology | Antifungal Agents - chemistry | Hypoglycemic Agents - chemistry | Antineoplastic Agents - chemistry | Anticonvulsants - pharmacology | Hypoglycemic Agents - pharmacology | Triazoles - pharmacology | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anticonvulsants - chemistry | Antiparasitic Agents - pharmacology | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Antiparasitic Agents - chemistry
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2012, Volume 20, Issue 11, pp. 3378 - 3395
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 8, pp. 3179 - 3189
This review summarizes recent medicinal chemistry investigations and in search for new phenothiazines of promising biological activities. New phenothiazine... 
Multi-drug resistance | Antifungal | Antibacterial | Azaphenothiazines | Anticancer | Phenothiazines | CHEMISTRY, MEDICINAL | MUSTARD TYPE PHENOTHIAZINES | SULFONE DERIVATIVES | ANTITUMOR-ACTIVITY | ANTICANCER ACTIVITY | ANTIMICROBIAL ACTIVITIES | RIBOFURANOSIDES | N-ACYLPHENOTHIAZINES | ANTITUBERCULAR ACTIVITY | INHIBITORS | MULTIDRUG-RESISTANCE | Analgesics - pharmacology | Drug Resistance, Multiple | Humans | Bacteria - drug effects | Cell Membrane Permeability | Trypanocidal Agents - chemistry | Antifungal Agents - chemistry | Structure-Activity Relationship | Anticonvulsants - pharmacology | Antiviral Agents - chemistry | Phenothiazines - pharmacology | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Immunosuppressive Agents - pharmacology | Antifungal Agents - pharmacology | Rabbits | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Solubility | Rats | Viruses - drug effects | Antineoplastic Agents - chemistry | Antimalarials - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Antipsychotic Agents - chemistry | Phenothiazines - chemistry | Trypanocidal Agents - pharmacology | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Mice | Antipsychotic Agents - pharmacology | Immunosuppressive Agents - chemistry
Journal Article
1999, Handbook of experimental pharmacology, ISBN 3540653740, Volume 138., xxxviii, 631
Book
Neuropharmacology, ISSN 0028-3908, 06/2013, Volume 69, pp. 115 - 126
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 7/2011, Volume 384, Issue 1, pp. 47 - 57
In epilepsy, allegedly, a neurotransmitter imbalance between the inhibitory GABA and the excitatory glutamate prevails. Therefore, some antiepileptic drugs... 
Neurosciences | Veratridine | Biomedicine | Epilepsy | GABA | Neocortical synaptosomes | Pharmacology/Toxicology | Antiepileptic drugs | Potassium | ACTION-POTENTIALS | VOLTAGE-DEPENDENT LIMITATION | TEMPORAL-LOBE EPILEPSY | NEUROTRANSMITTER RELEASE | VALPROIC ACID | TRANSPORTER GAT-1 | MOUSE CENTRAL NEURONS | IN-VITRO | SODIUM VALPROATE | PHARMACOLOGY & PHARMACY | CALCIUM-CHANNEL | Synaptosomes - drug effects | Rats, Wistar | gamma-Aminobutyric Acid - metabolism | Humans | Middle Aged | Child, Preschool | Infant | Male | Pregabalin | Synaptosomes - metabolism | Anticonvulsants - pharmacology | Valproic Acid - pharmacology | Calcium - deficiency | Young Adult | Calcium - antagonists & inhibitors | Neocortex - metabolism | Neocortex - drug effects | Piracetam - pharmacology | Adult | Female | Phenytoin - pharmacology | Tetrodotoxin - pharmacology | Nipecotic Acids - pharmacology | Child | Carbamazepine - pharmacology | Triazines - pharmacology | Rats | gamma-Aminobutyric Acid - pharmacology | Tetanus Toxin - pharmacology | Potassium - pharmacology | Veratridine - pharmacology | GABA Antagonists - pharmacology | Animals | Cyclohexanecarboxylic Acids - pharmacology | Piracetam - analogs & derivatives | Adolescent | Oximes - pharmacology | Aged | gamma-Aminobutyric Acid - analogs & derivatives | Amines - pharmacology | Phenytoin - pharmacokinetics | Drugs | Brain | Anticonvulsants | Marine toxins | Neurons | Tetanus | Glutamate | Sodium channels | gamma -Aminobutyric acid | Calcium | lamotrigine | Cortex | veratridine | tetanus toxin | Antiepileptic agents | Exocytosis | Valproic acid | Etiracetam | Carbamazepine | Depolarization | Neurotransmitters | Neural networks | gabapentin | Synaptosomes | Phenytoin
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2015, Volume 89, pp. 743 - 816
The biological activity of Mannich bases, a structurally heterogeneous class of chemical compounds that are generated from various substrates through the... 
Aminomethylation | Drug design | Mannich bases | Structure–activity relationships | Biological activity | Structure-activity relationships | Structureeactivity relationships | CHEMISTRY, MEDICINAL | ANTIMICROBIAL ACTIVITY EVALUATION | ONE-POT SYNTHESIS | PURINE NUCLEOSIDE PHOSPHORYLASE | STATE ANALOG INHIBITORS | B VIRUS ACTIVITIES | DOXORUBICIN-FORMALDEHYDE CONJUGATE | REGIOSELECTIVE REACTION SYNTHESIS | TITANOCENE ANTICANCER DRUGS | THYROID-HORMONE RECEPTOR | MYCOBACTERIUM-TUBERCULOSIS ISOCITRATE | Analgesics - pharmacology | Antioxidants - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Anticonvulsants - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Mannich Bases - chemical synthesis | Analgesics - chemical synthesis | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Drug Design | Mannich Bases - pharmacology | Antineoplastic Agents - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Antimalarials - chemical synthesis | Antifungal Agents - pharmacology | Antiviral Agents - pharmacology | Anticonvulsants - chemical synthesis | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Chemistry, Pharmaceutical | Mannich Bases - chemistry | Antimalarials - pharmacology | Anti-Bacterial Agents - chemical synthesis | Animals | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Antiviral Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Antioxidants | Antiviral agents | Enzymes | Mental illness | Bases (Chemistry)
Journal Article