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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2012, Volume 20, Issue 11, pp. 3378 - 3395
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 322 - 327
Na+/Cl--coupled biogenic amine transporters are the primary targets of therapeutic and abused drugs, ranging from antidepressants to the psychostimulants... 
BIOGENIC-AMINE TRANSPORTERS | COCAINE BINDING | SEROTONIN TRANSPORTER | SUBSTRATE TRANSPORT | BACTERIAL HOMOLOG | MULTIDISCIPLINARY SCIENCES | RAT-BRAIN SYNAPTOSOMES | CONFORMATIONAL DYNAMICS | ALTERNATING-ACCESS | TRANSMITTER UPTAKE | MAMMALIAN-CELLS | Dopamine - chemistry | Dopamine Plasma Membrane Transport Proteins - metabolism | Cocaine - metabolism | Molecular Conformation | Crystallography, X-Ray | Dopamine Plasma Membrane Transport Proteins - chemistry | Methamphetamine - chemistry | Sodium - metabolism | Antidepressive Agents - metabolism | Antidepressive Agents - chemistry | Chlorides - metabolism | Central Nervous System Stimulants - metabolism | Dextroamphetamine - chemistry | Protein Stability | Binding Sites | Dopamine - metabolism | Cocaine - chemistry | Dextroamphetamine - metabolism | Neurotransmitter Agents - metabolism | Models, Molecular | Phenethylamines - metabolism | Cocaine - analogs & derivatives | Methamphetamine - metabolism | Neurotransmitter Agents - chemistry | Animals | Dopamine - analogs & derivatives | Drosophila melanogaster - chemistry | Central Nervous System Stimulants - chemistry | Ligands | Physiological aspects | Neurotransmitters | Dopamine | Research | Neurological research | Biological transport | Methamphetamines | Mutagenesis | Antidepressants | Nervous system | Cocaine | Binding sites
Journal Article
Science of the Total Environment, ISSN 0048-9697, 2009, Volume 407, Issue 8, pp. 2760 - 2770
The occurrence and removal rate of seven pharmaceuticals (ibuprofen, naproxen, diclofenac, fluoxetine, ofloxacin, norfloxacin, ciprofloxacin), two metabolites... 
Removal rate | Endocrine disrupters | Wastewater treatment | Treated and untreated sewage | Pharmaceuticals | WASTE-WATER TREATMENT | ANTIBIOTICS | ACIDIC PHARMACEUTICALS | ENVIRONMENT | RIVER | ENVIRONMENTAL SCIENCES | LIQUID-EXTRACTION | TREATMENT PLANTS | ULTRA-TRACE LEVEL | RISK-ASSESSMENT | SOLID-PHASE EXTRACTION | Fluoroquinolones - chemistry | Anti-Bacterial Agents - analysis | Sewage - chemistry | Antidepressive Agents - analysis | Water Pollutants, Chemical - chemistry | Anti-Inflammatory Agents, Non-Steroidal - analysis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Fluoroquinolones - analysis | Water Purification | Water Pollutants, Chemical - analysis | Estrogens - analysis | Sweden | Estrogens - chemistry | Acetophenones - chemistry | Anti-Bacterial Agents - chemistry | Antidepressive Agents - chemistry | Pharmaceutical Preparations - chemistry | Pharmaceutical Preparations - analysis | Acetophenones - analysis | Purification | Fluoxetine | Aquatic resources | Sludge | Ofloxacin | Estradiol | Sewage | Metabolites | Water reuse | Naproxen | Ibuprofen | Ethinyl estradiol | Ciprofloxacin | Toxicity | Households | Ecosystems | Estrogens | Sewage treatment | Effluents | Raw | Outlets | Diclofenac | Inlets | Degradation | Hospitals | Mathematical analysis | Surface water | Sampling | Index Medicus | Naturvetenskap | Natural Sciences
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 02/2016, Volume 24, Issue 4, pp. 501 - 520
Natural products serve as a key source for the design, discovery and development of potentially novel drug like candidates for life threatening diseases.... 
Review | Feruloylmethane | Zingiber officinale | Curcumin degradants | Dehydrozingerone (DZG) | CHEMISTRY, MEDICINAL | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | SYNTHETIC CURCUMINOIDS | ANTIDEPRESSANT-LIKE ACTIVITY | EARLY ANTIGEN ACTIVATION | ANTIOXIDANT PROPERTIES | IN-VITRO | MONO-CARBONYL ANALOGS | ANTIINFLAMMATORY AGENTS | ZINGIBER-OFFICINALE | CYTOTOXIC AGENTS | Antioxidants - chemistry | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antifungal Agents - chemistry | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Curcumin - metabolism | Antidepressive Agents - isolation & purification | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Styrenes - pharmacology | Antimalarials - isolation & purification | Styrenes - chemistry | Antidepressive Agents - chemistry | Drug Design | Platelet Aggregation Inhibitors - pharmacology | Antidepressive Agents - pharmacology | Molecular Structure | Antifungal Agents - pharmacology | Platelet Aggregation Inhibitors - isolation & purification | Antineoplastic Agents, Phytogenic - chemistry | Antioxidants - pharmacology | Styrenes - isolation & purification | Antimalarials - pharmacology | Antifungal Agents - isolation & purification | Animals | Ginger - chemistry | Antioxidants - isolation & purification | Antimalarials - chemistry | Platelet Aggregation Inhibitors - chemistry | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7599, pp. 334 - 339
The serotonin transporter (SERT) terminates serotonergic signalling through the sodium-and chloride-dependent reuptake of neurotransmitter into presynaptic... 
HIGH-AFFINITY RECOGNITION | NEUROTRANSMITTER TRANSPORTERS | NOREPINEPHRINE TRANSPORTERS | N-LINKED GLYCOSYLATION | ALLOSTERIC BINDING | BACTERIAL HOMOLOG | MULTIDISCIPLINARY SCIENCES | BINDING-SITE | SELECTIVE RECOGNITION | MEMBRANE-PROTEINS | DOPAMINE TRANSPORTER | Citalopram - pharmacology | Humans | Protein Conformation - drug effects | Crystallography, X-Ray | Dopamine Plasma Membrane Transport Proteins - chemistry | Structure-Activity Relationship | Antidepressive Agents - metabolism | Citalopram - metabolism | Serotonin Plasma Membrane Transport Proteins - chemistry | Extracellular Space - metabolism | Antidepressive Agents - chemistry | Protein Binding - drug effects | Drug Design | Antidepressive Agents - pharmacology | Protein Stability | Allosteric Regulation - drug effects | Ions - chemistry | Serotonin Plasma Membrane Transport Proteins - immunology | Allosteric Site - drug effects | Models, Molecular | Ions - metabolism | Paroxetine - metabolism | Serotonin Plasma Membrane Transport Proteins - metabolism | Citalopram - chemistry | Intracellular Space - metabolism | Serotonin - metabolism | Ligands | Immunoglobulin Fab Fragments - immunology | Paroxetine - pharmacology | Paroxetine - chemistry | Drug metabolism | Paroxetine | Physiological research | Research | Serotonin | Binding sites (Biochemistry) | X rays | Mutation | Antidepressants | Binding sites
Journal Article