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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2008, Volume 105, Issue 22, pp. 7797 - 7802
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. E0194455
Mesenchymal stem cells (MSCs) can suppress dendritic cells (DCs) maturation and function, mediated by soluble factors, such as indoleamine 2,3-dioxygenase... 
ACTIVATION | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | ANTIGEN-PRESENTING CELLS | BLOOD MONOCYTES | DIFFERENTIATION | STROMAL CELLS | VERSUS-HOST-DISEASE | T-CELLS | IL-10 | Phosphorylation | Signal Transduction | Coculture Techniques | Dendritic Cells - immunology | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Rats | Immunophenotyping | Male | Tyrphostins - pharmacology | Lipopolysaccharides - immunology | Janus Kinase 1 - metabolism | Mesenchymal Stromal Cells - cytology | Animals | Interleukin-10 - metabolism | Dendritic Cells - drug effects | Interleukin-10 - secretion | Cell Differentiation | Dendritic Cells - cytology | Interleukin-10 - pharmacology | Interleukin-12 - secretion | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | B cells | Interleukins | Dendritic cells | Nitric oxide | Enzyme-linked immunosorbent assay | Stem cells | Cell culture | CD86 antigen | Mesenchyme | Interleukin | Prostaglandin E2 | Stem cell transplantation | Tryptophan 2,3-dioxygenase | Feedback loops | Kinases | Positive feedback | Monoculture | Signal transduction | Allografts | Lymphocytes | Rodents | Cell cycle | Bone marrow | Janus kinase | Inhibition | Cardiology | Antigens | CD11b antigen | Cytokines | Maturation | Secretion | Stat3 protein | Cultures | Interleukin 12 | CD80 antigen | T cell receptors | Studies | Signaling | Immunosuppression | Major histocompatibility complex | Skin & tissue grafts | Interleukin 10 | Immunofluorescence | Surface markers | Cancer
Journal Article
Allergy, ISSN 0105-4538, 11/2016, Volume 71, Issue 11, pp. 1561 - 1574
Background Signaling through histamine receptors on dendritic cells (DCs) may be involved in the effector phase of peanut‐induced intestinal anaphylaxis.... 
H1R | peanut allergy | dendritic cells | CD4+ T cells | H4R | CD4 | T cells | ALLERGIC INFLAMMATION | INDUCED AIRWAY INFLAMMATION | MAST-CELLS | T-CELL | IMMUNOLOGY | HYPERRESPONSIVENESS | RESPONSES | ALLERGY | LORATADINE | H-4 RECEPTOR | SKIN | CD4(+) T cells | EXPRESSION | Intestinal Mucosa - metabolism | Calcium - metabolism | Arachis - adverse effects | Dendritic Cells - immunology | Th2 Cells - immunology | Adoptive Transfer | Th2 Cells - drug effects | Intestinal Mucosa - drug effects | CD4-Positive T-Lymphocytes - immunology | Intestinal Mucosa - cytology | Th17 Cells - drug effects | Allergens - immunology | Th17 Cells - metabolism | Histamine H1 Antagonists - pharmacology | Intestinal Mucosa - immunology | Anaphylaxis - immunology | Histamine Antagonists - pharmacology | Dendritic Cells - drug effects | Female | Chemotaxis - immunology | Disease Models, Animal | Antigen-Presenting Cells - metabolism | Receptors, Histamine H4 - antagonists & inhibitors | Anaphylaxis - drug therapy | Cytokines - metabolism | Antigen-Presenting Cells - drug effects | Anaphylaxis - pathology | CD4-Positive T-Lymphocytes - metabolism | Chemotaxis - drug effects | Peanut Hypersensitivity - immunology | Transcription Factors - genetics | Antigen-Presenting Cells - immunology | Th2 Cells - metabolism | Transcription Factors - metabolism | Cell Lineage | Animals | Peanut Hypersensitivity - metabolism | Th17 Cells - immunology | Mice | Peanut Hypersensitivity - drug therapy | Peanut Hypersensitivity - pathology | Anaphylaxis - metabolism | CD4-Positive T-Lymphocytes - drug effects | Histamine receptors | Histamine | Food allergy | Allergens | Anaphylaxis | Dendritic cells | Analysis | Food allergies | Antigens | Lymphatic system | Inflammation | Rodents
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 07/2012, Volume 248, Issue 1, pp. 170 - 187
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31296
CD40L is essential for the development of adaptive immune responses. It is generally thought that CD40L expression in CD4(+) T cells is regulated... 
POSTTRANSCRIPTIONAL REGULATION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | THYMIC EPITHELIAL-CELLS | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | EFFECTOR FUNCTION | CD40-CD40 LIGAND | SECRETORY LYSOSOMES | TRANSGENIC MICE | CD8-Positive T-Lymphocytes - cytology | Inflammation - pathology | T-Lymphocytes, Regulatory - metabolism | Natural Killer T-Cells - drug effects | Thymocytes - metabolism | Protein Transport - drug effects | Th2 Cells - drug effects | Side-Population Cells - drug effects | T-Lymphocytes, Helper-Inducer - drug effects | Th1 Cells - metabolism | Interleukin-4 - pharmacology | Th17 Cells - drug effects | CD40 Ligand - metabolism | Th17 Cells - metabolism | Natural Killer T-Cells - metabolism | Side-Population Cells - metabolism | T-Lymphocytes, Helper-Inducer - cytology | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Th17 Cells - cytology | Th1 Cells - drug effects | Intracellular Space - drug effects | T-Lymphocytes, Helper-Inducer - metabolism | Mice, Inbred C57BL | Natural Killer T-Cells - cytology | Th2 Cells - cytology | Inflammation - immunology | Down-Regulation - drug effects | Side-Population Cells - cytology | Th2 Cells - metabolism | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Intracellular Space - metabolism | Staining and Labeling | Antigens - immunology | Thymocytes - cytology | Thymocytes - drug effects | Mice | Th1 Cells - cytology | Transcription | Helper cells | Central nervous system | Science | Effector cells | Critical care | Cytotoxicity | Viruses | Lipids | Activation | Lymphocytes T | CD40L protein | Invariants | Respiratory tract | Hepatitis | Cell activation | Immunology | Lymphocytes | Rodents | Natural killer cells | Encephalitis | Antigens | Antigen presentation | Immunological memory | Lymphatic system | Memory cells | Immunoglobulins | Immune response | Cytokines | Dendritic cells | T cell receptors | Experimental allergic encephalomyelitis | Asthma | CD4 antigen | Computer memory | Thymocytes | Lymphocytes B | Antigen-presenting cells | Influenza | Apoptosis
Journal Article
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7595, pp. 523 - 527
The integrated stress response (ISR) is a homeostatic mechanism by which eukaryotic cells sense and respond to stress-inducing signals, such as amino acid... 
OXIDATIVE STRESS | DENDRITIC CELLS | PHOSPHORYLATION | DEPRIVATION | EIF2-ALPHA KINASE | MULTIDISCIPLINARY SCIENCES | LOW-PROTEIN DIET | AUTOPHAGY | DIFFERENTIATION | TRANSLATION | TRANSGENIC MICE | Inflammation - pathology | Protein-Serine-Threonine Kinases - deficiency | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Stress, Physiological | Colitis - pathology | Male | Amino Acids - administration & dosage | Autophagy | Amino Acids - pharmacology | Amino Acids - metabolism | Inflammation - metabolism | Inflammasomes - antagonists & inhibitors | Female | Microtubule-Associated Proteins - deficiency | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Antigen-Presenting Cells - metabolism | Intestines - pathology | Ubiquitin-Activating Enzymes - deficiency | Protein-Serine-Threonine Kinases - genetics | Interleukin-1beta - immunology | Amino Acids - deficiency | Ubiquitin-Activating Enzymes - metabolism | Antigen-Presenting Cells - immunology | Inflammation - etiology | Autophagy-Related Protein 7 | Colitis - etiology | Animals | Autophagy-Related Protein 5 | Colitis - metabolism | Th17 Cells - immunology | Inflammation - prevention & control | Mice | Colitis - prevention & control | Medical research | Intestines | Medicine, Experimental | Amino acids | Inflammation | Research | Health aspects | Phosphotransferases | Immune system | Antigens | Phosphorylation | Dendritic cells | Tissue engineering | Kinases | Gene expression | Inflammatory bowel disease | Proteins | Rodents | Colon | Endoplasmic reticulum
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2046 - 2058
T cell Ig and ITIM domain (TIGIT) is an inhibitory receptor expressed by activated T cells, Tregs, and NI( cells. Here, we determined that TIGIT is upregulated... 
MEDICINE, RESEARCH & EXPERIMENTAL | ADHESION MOLECULE | LIGANDS | DNAM-1 | INHIBITORY RECEPTORS | CHRONIC VIRAL-INFECTION | NECTIN-2 CD112 | UP-REGULATION | PVR CD155 | EXPRESSION | POLIOVIRUS RECEPTOR CD155 | Up-Regulation | Receptors, Immunologic - physiology | Receptors, Virus - biosynthesis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Programmed Cell Death 1 Receptor - physiology | Receptors, Virus - genetics | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Interleukin-2 Receptor beta Subunit - genetics | Neoplasm Proteins - genetics | Antibodies, Monoclonal - immunology | Antigen-Presenting Cells - metabolism | Antigens, Neoplasm - immunology | Lymphocyte Activation | Neoplasm Proteins - biosynthesis | Antibodies, Monoclonal - pharmacology | Immunophenotyping | Interleukin-2 Receptor beta Subunit - biosynthesis | Melanoma - pathology | Antigen-Presenting Cells - immunology | Melanoma - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | T-Cell Antigen Receptor Specificity | Immunologic Memory | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Oncology | Immunology | Dermatology | Therapeutics
Journal Article