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Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4746 - 4757
Solid tumors are complex masses with a local microenvironment, or stroma, that supports tumor growth and progression. Among the diverse tumor-supporting... 
MEDICINE, RESEARCH & EXPERIMENTAL | CD8(+) | IMMUNOTHERAPY | INFILTRATING LYMPHOCYTES | INTERLEUKIN-12 | SUPPRESSOR-CELLS | ANTITUMOR IMMUNITY | GENE-TRANSFER | ANTIGEN-LOSS VARIANTS | CANCER | T-CELLS | CD8-Positive T-Lymphocytes - transplantation | Interleukin-12 - genetics | Stromal Cells - pathology | Myeloid Cells - physiology | Interleukin-12 - physiology | Neoplasm Proteins - immunology | Recombinant Fusion Proteins - physiology | Gene Expression Profiling | Lymphocyte Subsets - immunology | Antigen-Presenting Cells - pathology | Melanoma, Experimental - immunology | Antigen Presentation | Bone Marrow Cells - immunology | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Interleukin-12 - secretion | Lymphocyte Subsets - pathology | Tumor Escape - immunology | Macrophages - physiology | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - therapy | Bone Marrow Cells - pathology | Interferon-gamma - physiology | Melanoma, Experimental - pathology | Gene Expression Regulation, Neoplastic - immunology | Radiation Chimera | Antigen-Presenting Cells - immunology | Tumor Microenvironment - immunology | Animals | CD8-Positive T-Lymphocytes - secretion | Inflammation - genetics | Mice | Stromal Cells - physiology | Care and treatment | Interleukin-12 | Cancer cells | Genetic aspects | Research | Properties | Cancer
Journal Article