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Stem Cells, ISSN 1066-5099, 03/2010, Volume 28, Issue 3, pp. 564 - 572
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types. Chondrogenesis is induced in hMSCs cultured as a... 
Cell shape | Rac1 | Chondrogenesis | Smooth muscle cells | N-cadherin | Mesenchymal stem cells | MYOBLAST FUSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ADHESION | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | CYTOSKELETAL TENSION | DIFFERENTIATION | RHO-GTPASES | PROTEINS | HEMATOLOGY | MODULATION | MAMMARY EPITHELIAL-CELLS | Chondrocytes - cytology | Chondrogenesis - drug effects | Cadherins - metabolism | Humans | Extracellular Matrix - metabolism | Antigens, CD - genetics | Cell Lineage - drug effects | Transforming Growth Factor beta3 - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cadherins - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Cell Adhesion - genetics | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Mesenchymal Stromal Cells - metabolism | Up-Regulation - genetics | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion - drug effects | Cell Lineage - physiology | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Muscle Development - drug effects | rac1 GTP-Binding Protein - drug effects | Cell Differentiation - drug effects | Cell Shape - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2012, Volume 13, Issue 2, pp. 188 - 195
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 03/2011, Volume 11, Issue 5, pp. 464 - 473
Curcumin is a polyphenolic compound derived from the Indian spice turmeric. We used nanoparticle-encapsulated curcumin to treat medulloblastoma and... 
Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | Hedgehog | Medulloblastoma | Nanocurcumin | Glioblastoma | IGF | Curcumin | NanoCurc | NEURAL PROGENITORS | SIGNALING PATHWAYS | ACTIVATION | nanocurcumin | medulloblastoma | PANCREATIC-CANCER | nanoCurc (TM) | MEDULLOBLASTOMA CELLS | INSULIN | glioblastoma | hedgehog | ONCOLOGY | FACTOR-I RECEPTOR | NF-KAPPA-B | EXPRESSION | GLIOBLASTOMA CELLS | curcumin | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Curcumin - chemistry | Humans | Nanocapsules | Receptors, Notch - genetics | Glycoproteins - drug effects | Antineoplastic Agents - administration & dosage | Curcumin - administration & dosage | Hedgehog Proteins - genetics | Medulloblastoma - pathology | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Polymers | Neoplastic Stem Cells - physiology | Tumor Stem Cell Assay | Curcumin - pharmacology | Hedgehog Proteins - analysis | STAT3 Transcription Factor - analysis | Medulloblastoma - metabolism | Antigens, CD - drug effects | Antineoplastic Agents - chemistry | Down-Regulation - drug effects | AC133 Antigen | Peptides - drug effects | Receptors, Notch - analysis | Mitosis - drug effects | Signal Transduction - drug effects | Glioblastoma - pathology | Somatomedins - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Glioblastoma - drug therapy | Medulloblastoma - drug therapy | Index Medicus | nanoCurc | Research Paper
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 2210 - 20
VEGFR-2/Notch signalling regulates angiogenesis in part by driving the remodelling of endothelial cell junctions and by inducing cell migration. Here, we show... 
TIP CELLS | PERMEABILITY | ELONGATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RHO | RAC1 | BETA-CATENIN | ENDOCYTOSIS | FLOW | VASCULAR ENDOTHELIAL-CADHERIN | Human Umbilical Vein Endothelial Cells | Neovascularization, Physiologic - drug effects | Vascular Remodeling | Cadherins - metabolism | Humans | Actins - metabolism | rac GTP-Binding Proteins - metabolism | Actins - drug effects | Vascular Endothelial Growth Factor A - metabolism | Cell Movement - physiology | Antigens, CD - metabolism | Pseudopodia - drug effects | Actin-Related Protein 2-3 Complex - metabolism | Microtubules - metabolism | Microtubules - drug effects | Actin-Related Protein 3 - metabolism | Wiskott-Aldrich Syndrome Protein - metabolism | Actin-Related Protein 2 - metabolism | Cell Polarity - drug effects | Vascular Endothelial Growth Factor A - pharmacology | Cardiac Myosins - metabolism | Endothelial Cells - physiology | Signal Transduction | Wiskott-Aldrich Syndrome Protein Family - metabolism | Endothelial Cells - metabolism | Models, Cardiovascular | Intercellular Junctions - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion | Cell Movement - drug effects | Neovascularization, Physiologic - physiology | Pseudopodia - metabolism | Intercellular Junctions - drug effects | Cell Polarity - physiology | Myosin Light Chains - metabolism | Pseudopodia - physiology | Endothelium, Vascular | Endothelial Cells - drug effects | Cell junctions | Pseudopodia | Dephosphorylation | Cadherin | Remodeling | Contraction | Endothelial cells | Cell adhesion & migration | Vascular endothelial growth factor receptors | Prisons | Angiogenesis | Signaling | Cell activation | Actin | Microtubules | Myosin | Notch protein | Vascular endothelial growth factor | Cell migration | Elongation | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2010, Volume 184, Issue 12, pp. 7257 - 7267
To elucidate the molecular action of 8-methoxypsoralen plus UVA (PUVA), a standard dermatological therapy, we used K5. hTGF-beta 1 transgenic mice exhibiting a... 
INDUCED IMMUNE SUPPRESSION | GROWTH-FACTOR-BETA | ACTIVATION | TGF-BETA | MYELOID DENDRITIC CELLS | IN-VIVO | CONTACT HYPERSENSITIVITY | DOWN-REGULATION | IMMUNOLOGY | PLAQUE-TYPE PSORIASIS | PSORALEN | Forkhead Transcription Factors - immunology | Immunohistochemistry | T-Lymphocyte Subsets - immunology | Antigens, CD - immunology | Immunoassay | Humans | Methoxsalen - administration & dosage | Forkhead Transcription Factors - drug effects | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Regulatory - radiation effects | Photosensitizing Agents - administration & dosage | Signal Transduction - immunology | Flow Cytometry | Ultraviolet Rays | T-Lymphocyte Subsets - drug effects | Signal Transduction - radiation effects | Antigens, CD - radiation effects | Disease Models, Animal | Psoriasis - therapy | Psoriasis - immunology | Transforming Growth Factor beta - immunology | Enzyme-Linked Immunosorbent Assay | Cell Separation | Interleukin-17 - radiation effects | Mice, Transgenic | T-Lymphocyte Subsets - radiation effects | Antigens, CD - drug effects | Forkhead Transcription Factors - radiation effects | Reverse Transcriptase Polymerase Chain Reaction | Phototherapy | CTLA-4 Antigen | T-Lymphocytes, Regulatory - drug effects | Animals | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Interleukin-23 - radiation effects | Fluorescent Antibody Technique | Mice | Interleukin-23 - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6623 - 6623
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2007, Volume 13, Issue 7, pp. 2151 - 2157
Journal Article
Experimental Neurology, ISSN 0014-4886, 2007, Volume 203, Issue 1, pp. 42 - 54
Paclitaxel-induced peripheral neuropathy (PN) can be a significant problem for patients receiving chemotherapeutic regimens for the treatment of breast,... 
Axonopathy | Neurotoxicity | Breast cancer | Ganglionopathy | Neuropathic pain | Microglia | axonopathy | TACTILE ALLODYNIA | breast cancer | SPINAL-CORD | SATELLITE CELLS | OVARIAN-CANCER | BONE CANCER PAIN | ACTIVATING TRANSCRIPTION FACTOR-3 | ganglionopathy | DORSAL-ROOT GANGLION | NEUROSCIENCES | NERVE GROWTH-FACTOR | neuropathic pain | neurotoxicity | MESSENGER-RNA | SCIATIC-NERVE | microglia | Hyperalgesia - chemically induced | Microglia - metabolism | Posterior Horn Cells - drug effects | Peripheral Nervous System Diseases - chemically induced | Posterior Horn Cells - metabolism | Injections, Intravenous | Antigens, Differentiation, Myelomonocytic - drug effects | Male | CD11b Antigen | Peripheral Nervous System Diseases - physiopathology | Glial Fibrillary Acidic Protein - metabolism | Peripheral Nerves - drug effects | Satellite Cells, Perineuronal - metabolism | Antigens, CD - metabolism | Chemotaxis, Leukocyte - physiology | Hyperalgesia - pathology | Activating Transcription Factor 3 - drug effects | Paclitaxel - toxicity | Chemotaxis, Leukocyte - drug effects | Microglia - pathology | Neurons, Afferent - pathology | Peripheral Nervous System Diseases - pathology | Disease Models, Animal | Schwann Cells - drug effects | Neurons, Afferent - drug effects | Microglia - drug effects | Rats | Schwann Cells - pathology | Schwann Cells - metabolism | Antigens, CD - drug effects | Activating Transcription Factor 3 - metabolism | Peripheral Nerves - pathology | Rats, Sprague-Dawley | Hyperalgesia - physiopathology | Peripheral Nerves - physiopathology | Antineoplastic Agents, Phytogenic - toxicity | Satellite Cells, Perineuronal - drug effects | Macrophages - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Glial Fibrillary Acidic Protein - drug effects | Ganglia, Spinal - pathology | Posterior Horn Cells - pathology | Macrophages - drug effects | Neurons, Afferent - metabolism | Ganglia, Spinal - drug effects | Satellite Cells, Perineuronal - pathology | Ganglia, Spinal - metabolism | Antimitotic agents | Chemotherapy | Infiltration (Military science) | Neurosciences | Neurons | Oncology, Experimental | Lung cancer | Research | Macrophages | Antineoplastic agents | Intermediate filament proteins | Cancer | Index Medicus
Journal Article
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 07/2015, Volume 67, Issue 7, pp. 1766 - 1777
ObjectiveRheumatoid arthritis (RA), one of the most frequent chronic inflammatory rheumatic disorders, is characterized by the presence of autoantibodies and... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | FC-ALPHA-RI | GAMMA RECEPTORS | II COLLAGEN | INTRAVENOUS IMMUNOGLOBULIN | MONOCYTE ACTIVATION | ANTIBODY-INDUCED ARTHRITIS | RHEUMATOLOGY | MONOCLONAL-ANTIBODIES | JOINT INFLAMMATION | Leukocytes - pathology | Arthritis, Experimental - drug therapy | Humans | Synovial Membrane - pathology | Male | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - physiology | Synovial Membrane - drug effects | Phagocytes - pathology | Antigens, CD - genetics | Case-Control Studies | Arthritis, Experimental - pathology | Chemotaxis - physiology | Female | Receptors, Fc - drug effects | Receptors, Fc - physiology | Disease Models, Animal | Immunoglobulin A - therapeutic use | Cell Line | Arthritis, Experimental - physiopathology | Phagocytes - drug effects | Mice, Inbred C57BL | Cells, Cultured | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - drug effects | Immunoglobulin A - pharmacology | Mice, Transgenic | Antigens, CD - drug effects | Chemotaxis - drug effects | Arthritis, Rheumatoid - pathology | Animals | Signal Transduction - drug effects | Antigens, CD - physiology | Leukocytes - drug effects | Receptors, Fc - genetics | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | In Vitro Techniques | Arthritis | Phosphatase | Transgenic animals | Rodents | Index Medicus | Abridged Index Medicus
Journal Article