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The Journal of immunology (1950), ISSN 1550-6606, 2014, Volume 193, Issue 2, pp. 961 - 969
Immunotherapy aiming at enhancing innate and acquired host immunity is a promising approach for cancer treatment. The invariant NKT (iNKT) cell ligand... 
IMMUNITY | ACTIVATION | CANCER-PATIENTS | VIVO | KRN7000 | KILLER T-CELLS | CYTOKINE BIAS | ANTIGEN PRESENTATION | ANERGY | IMMUNOLOGY | TLR LIGANDS | Antigens, CD - immunology | Nanoparticles - chemistry | Minor Histocompatibility Antigens | Antibodies - chemistry | Dendritic Cells - immunology | Lectins, C-Type - immunology | Male | Galactosylceramides - administration & dosage | Neoplasms, Experimental - pathology | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | Natural Killer T-Cells - metabolism | Neoplasms, Experimental - immunology | Antibodies - immunology | CD8-Positive T-Lymphocytes - metabolism | Dendritic Cells - metabolism | T-Lymphocytes, Cytotoxic - immunology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Mice, Transgenic | Receptors, Antigen, T-Cell, gamma-delta - immunology | Antigen Presentation - immunology | Galactosylceramides - chemistry | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | Mice, Knockout | CD8 Antigens - metabolism | Animals | Galactosylceramides - immunology | T-Lymphocytes, Cytotoxic - metabolism | Cell Line, Tumor | T-Lymphocytes - immunology | Mice | Nanoparticles - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Drug Delivery Systems - methods | Natural Killer T-Cells - immunology | Tumor Burden - immunology | Nanoparticles/administration & dosage | Receptors, Cell Surface/immunology | Neoplasms, Experimental/therapy | CD8 Antigens/metabolism | Dendritic Cells/metabolism | Innate immunity | Galactosylceramides/immunology | Antigen Presentation/immunology | Natural Killer T-Cells/metabolism | Receptors, Antigen, T-Cell, gamma-delta/metabolism | Life Sciences | Galactosylceramides/chemistry | Lectins, C-Type/immunology | CD8-Positive T-Lymphocytes/immunology | Antigens, CD/immunology | Immunology | Antibodies/chemistry | Antibodies/immunology | T-Lymphocytes, Cytotoxic/metabolism | T-Lymphocytes/metabolism | Drug Delivery Systems/methods | T-Lymphocytes/immunology | CD8-Positive T-Lymphocytes/metabolism | Galactosylceramides/administration & dosage | Natural Killer T-Cells/immunology | Receptors, Antigen, T-Cell, gamma-delta/immunology | CD8 Antigens/immunology | Tumor Burden/immunology | Neoplasms, Experimental/immunology | Lymphocyte Activation/immunology | Nanoparticles/chemistry | Dendritic Cells/immunology | T-Lymphocytes, Cytotoxic/immunology | Neoplasms, Experimental/pathology
Journal Article
Mucosal immunology, ISSN 1933-0219, 01/2016, Volume 9, Issue 1, pp. 24 - 37
HIV-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. Dendritic cells (DCs) are... 
TRANSLOCATION | RESPONSES | LYMPHOID-TISSUE | INFLAMMATION | PREDICT MORTALITY | IMMUNE ACTIVATION | ANTIRETROVIRAL THERAPY | INTESTINAL LAMINA PROPRIA | IMMUNOLOGY | VIRUS TYPE-1 INFECTION | SIV INFECTION | Antigens, CD - immunology | Immunoglobulins - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Colon - immunology | Male | Immunoglobulins - genetics | Antigens, CD - genetics | Case-Control Studies | Viral Load | Ruminococcus - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV Infections - microbiology | Prevotella - immunology | HIV Infections - pathology | Prevotella - growth & development | Adult | Female | CD40 Antigens - genetics | Interferon-gamma - genetics | Membrane Glycoproteins - immunology | Ruminococcus - growth & development | Glycoproteins - genetics | Antigens, CD1 - immunology | CD4-Positive T-Lymphocytes - microbiology | CD8-Positive T-Lymphocytes - microbiology | Signal Transduction | Lymphocyte Activation | Gene Expression Regulation | Membrane Glycoproteins - genetics | Glycoproteins - immunology | HIV-1 - immunology | Mucous Membrane - immunology | Interferon-gamma - immunology | Dendritic Cells - microbiology | Colon - microbiology | Antigens, CD1 - genetics | Gastrointestinal Microbiome - immunology | CD8-Positive T-Lymphocytes - immunology | CD40 Antigens - immunology | Mucous Membrane - microbiology | Cell Lineage - immunology | mucosal immunology | HIV-1 pathogenesis | microbiome | Human intestinal dendritic cells
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2010, Volume 207, Issue 1, pp. 189 - 206
Recent studies have challenged the view that Langerhans cells (LCs) constitute the exclusive antigen-presenting cells of the skin and suggest that the dermal... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESIDENT DCS | MARGINAL ZONE | IN-VIVO | LYMPH-NODES | STEADY-STATE | BIRBECK GRANULES | MICE | SELF-ANTIGENS | SKIN | IMMUNOLOGY | T-CELLS | Antigens, CD - immunology | Lectins, C-Type - immunology | Lectins, C-Type - genetics | Antigens, CD - genetics | Integrin alpha Chains - immunology | Langerhans Cells - immunology | Female | Dermis - cytology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Antigens, Surface - genetics | Gene Expression Regulation - physiology | Mice, Transgenic | Keratinocytes - cytology | Lymph Nodes - immunology | Lymph Nodes - cytology | Organ Specificity | Dermis - immunology | Keratinocytes - immunology | Gene Knock-In Techniques | Animals | Histocompatibility Antigens Class II - immunology | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - immunology | Antigens - immunology | Mice | Histocompatibility Antigens Class II - genetics | Antigens, Surface - immunology | Integrin alpha Chains - genetics | Antigen Presentation - physiology | Langerhans Cells - cytology | Antigens - genetics | Antigens | Mannose-Binding Lectins | Langerhans Cells | Lectins, C-Type | Gene Expression Regulation | Keratinocytes | Dermis | Lymph Nodes | Life Sciences | Immunology | Antigen Presentation | Histocompatibility Antigens Class II | Antigens, Surface | Integrin alpha Chains | Antigens, CD
Journal Article
The Journal of immunology (1950), ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism
Journal Article
Journal of neurovirology, ISSN 1538-2443, 2015, Volume 22, Issue 2, pp. 191 - 200
Cell-free mitochondiral DNA (mtDNA) is an immunogenic molecule associated with many inflammatory conditions. We evaluated the relationship between cell-free... 
Neurology | Neurosciences | Biomedicine | Immunology | Infectious Diseases | Pleocytosis | Mitochondrial DNA | Inflammation | Droplet digital PCR | HAND | Virology | BRAIN-INJURY | CEREBROSPINAL-FLUID | NEUROSCIENCES | IMPAIRMENT | HEART | PLASMA | VIROLOGY | NEOPTERIN | DISEASE | DNA, Mitochondrial - cerebrospinal fluid | Chemokine CCL2 - immunology | Lipopolysaccharide Receptors - cerebrospinal fluid | Humans | Memory | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Male | Antigens, CD - genetics | Learning | Neurofilament Proteins - cerebrospinal fluid | Chemokine CCL2 - cerebrospinal fluid | HIV Infections - immunology | Neurofilament Proteins - genetics | Cognitive Dysfunction - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-6 - cerebrospinal fluid | Antigens, Differentiation, Myelomonocytic - cerebrospinal fluid | HIV Infections - cerebrospinal fluid | Gene Expression | Interleukin-6 - genetics | Tumor Necrosis Factor-alpha - cerebrospinal fluid | Lipopolysaccharide Receptors - immunology | Cognitive Dysfunction - cerebrospinal fluid | Cognitive Dysfunction - pathology | Receptors, Cell Surface - immunology | Neuropsychological Tests | Antigens, CD - cerebrospinal fluid | HIV Infections - complications | Interleukin-6 - immunology | Receptors, Cell Surface - genetics | Antigens, CD - immunology | HIV-1 - physiology | HIV Infections - pathology | Chemokine CXCL10 - immunology | Adult | Female | Neopterin - immunology | Cognitive Dysfunction - complications | Neurofilament Proteins - immunology | Executive Function | Antigens, Differentiation, Myelomonocytic - immunology | Severity of Illness Index | Chemokine CXCL10 - cerebrospinal fluid | Neopterin - cerebrospinal fluid | Cross-Sectional Studies | Chemokine CCL2 - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Chemokine CXCL10 - genetics | Lipopolysaccharide Receptors - genetics
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2013, Volume 14, Issue 12, pp. 1294 - 1301
Tissue-resident memory T cells (TRM cells) provide superior protection against infection in extralymphoid tissues. Here we found that CD103(+)CD8(+) TRM cells... 
MIGRATION | EFFECTOR | INTESTINAL EPITHELIUM | NONLYMPHOID TISSUE | RM CELLS | PERIPHERAL-TISSUES | DIFFERENTIATION | IMMUNOLOGY | LYMPHOCYTE EGRESS | CD103 EXPRESSION | CUTTING EDGE | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - immunology | Oligonucleotide Array Sequence Analysis | Skin - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | Lectins, C-Type - metabolism | Herpesvirus 1, Human - physiology | Integrin alpha Chains - immunology | CD8-Positive T-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Antigens, Differentiation, T-Lymphocyte - metabolism | Mice, Transgenic | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Herpes Simplex - immunology | Mice, Knockout | Cell Differentiation - immunology | Herpes Simplex - virology | Interleukin-15 - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Antigens, CD - immunology | Lectins, C-Type - immunology | Transcriptome - immunology | Lectins, C-Type - genetics | Interleukin-15 - immunology | Cell Differentiation - genetics | Signal Transduction - immunology | Flow Cytometry | Herpesvirus 1, Human - immunology | Receptors, Immunologic - immunology | Skin - virology | Immunologic Memory - immunology | Skin - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Integrin alpha Chains - metabolism | Transcriptome - genetics | Mice, Inbred Strains | Animals | Interleukin-15 - genetics | Receptors, Transforming Growth Factor beta - metabolism | CD8-Positive T-Lymphocytes - virology | Antigens, Differentiation, T-Lymphocyte - genetics | Protein-Serine-Threonine Kinases - immunology | Integrin alpha Chains - genetics | Receptors, Immunologic - metabolism
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 517, Issue 7534, pp. 386 - 390
Journal Article