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Circulation Research, ISSN 0009-7330, 09/2011, Volume 109, Issue 7, pp. 724 - 728
RATIONALE:Transplantation of human CD34 stem cells to ischemic tissues has been associated with reduced angina, improved exercise time, and reduced amputation... 
cells | CD34 | angiogenesis | exosomes | paracrine factor | CARDIAC & CARDIOVASCULAR SYSTEMS | CD34(+) cells | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Corneal Neovascularization - immunology | Exosomes - metabolism | Stem Cells - immunology | Antigens, CD34 - metabolism | Humans | Male | Stem Cells - metabolism | Antigens, CD - metabolism | DNA-Binding Proteins - metabolism | Flow Cytometry | Light | Platelet Membrane Glycoproteins - metabolism | Exosomes - immunology | Scattering, Radiation | Exosomes - ultrastructure | Biomarkers - metabolism | Microscopy, Electron, Transmission | Paracrine Communication | Endothelial Cells - metabolism | Phosphatidylserines - metabolism | Cells, Cultured | Endosomal Sorting Complexes Required for Transport - metabolism | Blotting, Western | Stem Cells - ultrastructure | Particle Size | Transcription Factors - metabolism | Animals | Corneal Neovascularization - metabolism | Tetraspanin 30 | Mice, Nude | Mice | Angiogenic Proteins - metabolism | Neovascularization, Physiologic | Culture Media, Conditioned - metabolism | CD34 antigen | Cell proliferation | Flow cytometry | Cornea | Physical training | CD63 antigen | Light scattering | Clinical trials | Paracrine signalling | Cell lineage | Data processing | Immunoblotting | Leukocytes (mononuclear) | Endothelial cells | Angiogenesis | Ischemia | Stem cells | vascularization | Index Medicus
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 08/2011, Volume 109, Issue 4, pp. 428 - 436
RATIONALE:A growing number of patients with coronary disease have refractory angina. Preclinical and early-phase clinical data suggest that intramyocardial... 
stem cells | angiogenesis | endothelial progenitor cells (EPC) myocardial ischemia | myocardial regeneration | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CELL TRANSPLANTATION | RANDOMIZED CONTROLLED-TRIAL | RESEARCH ISSUES | METASTATIC COLORECTAL-CANCER | PERCUTANEOUS CORONARY INTERVENTION | HEART-DISEASE | UNIVERSAL DEFINITION | DOUBLE-BLIND | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ARTERY-DISEASE | Antigens, CD34 - metabolism | Prospective Studies | Angina Pectoris - mortality | Angina Pectoris - physiopathology | United States | Humans | Middle Aged | Endothelial Cells - transplantation | Tomography, Emission-Computed, Single-Photon | Male | Transplantation, Autologous | Angina Pectoris - etiology | Blood Component Removal | Angina Pectoris - pathology | Microcirculation | Exercise Test | Time Factors | Hematopoietic Stem Cell Transplantation - adverse effects | Myocardial Ischemia - physiopathology | Female | Surveys and Questionnaires | Myocardial Ischemia - mortality | Hematopoietic Stem Cell Mobilization | Biomarkers - metabolism | Coronary Circulation | Double-Blind Method | Risk Assessment | Risk Factors | Myocardium - pathology | Treatment Outcome | Myocardial Ischemia - pathology | Endothelial Cells - immunology | Cardiovascular Agents - therapeutic use | Regeneration | Regression Analysis | Angina Pectoris - surgery | Myocardial Ischemia - complications | Exercise Tolerance | Least-Squares Analysis | Aged | Myocardial Ischemia - surgery | Neovascularization, Physiologic | Index Medicus
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 01/2013, Volume 112, Issue 1, pp. 165 - 173
RATIONALE:CD34 transplantation in dilated cardiomyopathy was associated with short-term improvement in left ventricular ejection fraction and exercise... 
heart failure | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | CD34(+) cells | bone marrow cells | BONE-MARROW | HEART-FAILURE | granulocyte colony-stimulating factor mobilization | TRIAL | ENDOTHELIAL PROGENITOR CELLS | DISEASES | ACUTE MYOCARDIAL-INFARCTION | IMPROVEMENT | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | dilated cardiomyopathy | Multivariate Analysis | Stem Cells - immunology | Cardiomyopathy, Dilated - pathology | Antigens, CD34 - metabolism | Myocardium - immunology | Follow-Up Studies | Ventricular Function, Left | Cardiomyopathy, Dilated - surgery | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Male | Cause of Death | Recovery of Function | Cell Tracking | Myocardial Perfusion Imaging | Exercise Test | Time Factors | Interleukin-6 - blood | Peptide Fragments - blood | Cardiomyopathy, Dilated - diagnosis | Female | Slovenia | Stem Cell Transplantation - mortality | Cardiomyopathy, Dilated - mortality | Natriuretic Peptide, Brain - blood | Biomarkers - metabolism | Coronary Circulation | Echocardiography | Cardiomyopathy, Dilated - blood | Kaplan-Meier Estimate | Proportional Hazards Models | Myocardium - pathology | Treatment Outcome | California | Chi-Square Distribution | Stroke Volume | Cardiomyopathy, Dilated - physiopathology | Texas | Cardiomyopathy, Dilated - immunology | Exercise Tolerance | Cell Movement | Injections, Intra-Arterial | Stem Cell Transplantation - adverse effects | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 04/2017, Volume 120, Issue 9, pp. 1466 - 1476
RATIONALE:Paracrine secretions seem to mediate therapeutic effects of human CD34 stem cells locally transplanted in patients with myocardial and critical limb... 
cell transplantation | stem cells | exosomes | hindlimb | Cardiovascular disease | microRNA | ischemia | CARDIAC-FUNCTION | PROGENITOR CELLS | CIRCULATING MICRORNAS | cardiovascular disease | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | RANDOMIZED PHASE-1 TRIAL | HEART | THERAPY | EXTRACELLULAR VESICLES | VASCULAR INTEGRITY | PERIPHERAL VASCULAR DISEASE | NEOVASCULARIZATION | HEMATOLOGY | Exosomes - metabolism | Angiogenic Proteins - genetics | Hindlimb | Antigens, CD34 - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | MicroRNAs - metabolism | Ischemia - genetics | Motor Activity | Recovery of Function | Transfection | RNA Interference | Time Factors | Endothelial Progenitor Cells - transplantation | Disease Models, Animal | Endothelial Progenitor Cells - metabolism | Muscle, Skeletal - blood supply | Biomarkers - metabolism | Exosomes - transplantation | Paracrine Communication | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Ischemia - metabolism | Ischemia - physiopathology | Regional Blood Flow | Phenotype | Animals | Ischemia - surgery | Mice, Inbred BALB C | MicroRNAs - genetics | Angiogenic Proteins - metabolism | Neovascularization, Physiologic | Culture Media, Conditioned - metabolism | CD34 antigen | Animal models | Angiopoietin | Secretion | MiRNA | Stem cell transplantation | Paracrine signalling | Smooth muscle | Secretions | Exosomes | Endothelial cells | Gelatinase B | Endothelium | Angiogenesis | Ischemia | Perfusion | Rodents | Amputation | Stem cells | Fibroblasts | Metalloproteinase | Vascular endothelial growth factor | Thrombospondin | Index Medicus | angiogenesis | Stem cell therapy | Cell Therapy | Stem Cells | stem cell | Cell Signaling | translational studies | CD34+ cells
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2016, Volume 213, Issue 8, pp. 1513 - 1535
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 123, Issue 2, pp. 472 - 478.e1
Journal Article