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1. Full Text Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
by Robicsek, O and Karry, R and Petit, I and Salman-Kesner, N and Müller, F.-J and Klein, E and Aberdam, D and Ben-Shachar, D
Molecular Psychiatry, ISSN 1359-4184, 10/2013, Volume 18, Issue 10, pp. 1067 - 1076
One of the prevailing hypotheses suggests schizophrenia as a neurodevelopmental disorder, involving dysfunction of dopaminergic and glutamatergic systems.... 
schizophrenia | neural differentiation | mitochondria | iPSC | SURVIVAL | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | NEUROSCIENCES | DOPAMINE NEURONS | NEURODEVELOPMENTAL DISORDERS | INHIBITION | METABOLISM | COMPLEX-I | GLUTAMATE | RESPIRATION | PSYCHIATRIC-DISORDERS | Neurons - pathology | Humans | Neurogenesis | Hair Follicle - pathology | RNA, Messenger - biosynthesis | Dopamine Agents - pharmacology | Excitatory Amino Acid Agents - pharmacology | Membrane Potential, Mitochondrial | Nerve Tissue Proteins - biosynthesis | Neurons - metabolism | Schizophrenia, Paranoid - pathology | Neurons - drug effects | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Oxygen Consumption | Mitochondria - metabolism | Nerve Tissue Proteins - genetics | Cell Lineage | Ectoderm - cytology | Antigens, Differentiation - biosynthesis | Keratinocytes - pathology | Schizophrenia, Paranoid - metabolism | Antigens, Differentiation - genetics | Models, Neurological | Physiological aspects | Schizophrenia | Genetic aspects | Mitochondrial DNA | Hair follicles | Diagnosis
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2. Full Text Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells
by Mummery, Christine and Ward-van Oostwaard, Dorien and Doevendans, Pieter and Spijker, Rene and van den Brink, Stieneke and Hassink, Rutger and van der Heyden, Marcel and Opthof, Tobias and Pera, Martin and de la Riviere, Aart Brutel and Passier, Robert and Tertoolen, Leon
Circulation, ISSN 0009-7322, 2003, Volume 107, Issue 21, pp. 2733 - 2740
Cardiomyocytes derived from human embryonic stem (hES) cells could be useful in restoring heart function after myocardial infarction or in heart failure. Here,... 
Electrophysiology | Stem cells | Myocytes | stem cells | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | VASCULOGENESIS | MOUSE | SIGNALS | myocytes | LINES | HEART | PRIMITIVE-STREAK | electrophysiology | GROWTH | PERIPHERAL VASCULAR DISEASE | Cell Line | Ion Channels - biosynthesis | Myocytes, Cardiac - cytology | Viscera - cytology | Calcium Signaling - physiology | Coculture Techniques | Heart - embryology | Humans | Cell Communication | Stem Cells - cytology | Myocardium - cytology | Action Potentials - physiology | Cell Lineage | Antigens, Differentiation - biosynthesis | Patch-Clamp Techniques | Animals | Endoderm - cytology | Myocytes, Cardiac - physiology | Mice | Cell Differentiation - physiology | Fluorescent Dyes
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3. Full Text An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile
by Pinto, Alexander R and Paolicelli, Rosa and Salimova, Ekaterina and Gospocic, Janko and Slonimsky, Esfir and Bilbao-Cortes, Daniel and Godwin, James W and Rosenthal, Nadia A
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36814
Cardiac tissue macrophages (cTMs) are a previously uncharacterised cell type that we have identified and characterise here as an abundant GFP(+) population... 
GROWTH FACTOR-I | GENE SIGNATURE | STEM-CELLS | MUSCLE REGENERATION | FRACTALKINE RECEPTOR | MONOCYTE | DENDRITIC CELLS | VIVO | MULTIDISCIPLINARY SCIENCES | DIET-INDUCED OBESITY | ADIPOSE-TISSUE | Antigens, CD - biosynthesis | Leukocyte Common Antigens - biosynthesis | Brain - metabolism | Myocardium - metabolism | Receptors, Cell Surface - biosynthesis | Macrophage Activation - physiology | Antigens, Differentiation, Myelomonocytic - biosynthesis | Brain - cytology | Insulin-Like Growth Factor I - biosynthesis | Myocytes, Cardiac - cytology | Endothelial Cells - metabolism | Mice, Transgenic | Spleen - cytology | Macrophages - cytology | Myocardium - cytology | Glycoproteins - biosynthesis | Antigens, Differentiation - biosynthesis | Macrophages - metabolism | Animals | Spleen - metabolism | Endothelial Cells - cytology | Homeostasis - physiology | Myocytes, Cardiac - metabolism | Mice | CD11b Antigen - biosynthesis | Macrophages | Gene expression | Analysis | Heart | Brain | Flow cytometry | Heart attacks | Laboratories | Insulin-like growth factor I | Homeostasis | Insulin-like growth factors | Blood | CD45 antigen | Ethics | Immunology | Transgenic animals | Bone marrow | Trends | Heart diseases | Spleen | Antigens | Enzymes | CD11b antigen | Immunomodulation | Secretion | Markers | Cardiomyocytes | Inflammation | Endothelial cells | Medicine | CD163 antigen | Cytometry | Stem cells | Myocardium | Molecular biology
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4. Full Text T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures
by Kennedy, Marion and Awong, Geneve and Sturgeon, Christopher M and Ditadi, Andrea and LaMotte-Mohs, Ross and Zúñiga-Pflücker, Juan Carlos and Keller, Gordon
Cell Reports, ISSN 2211-1247, 12/2012, Volume 2, Issue 6, pp. 1722 - 1735
The efficient generation of hematopoietic stem cells from human pluripotent stem cells is dependent on the appropriate specification of the definitive... 
PRIMITIVE STREAK | IN-VITRO | YOLK-SAC | MOUSE | GONAD-MESONEPHROS REGION | GENERATION | HUMAN EMBRYO | GROWTH-FACTOR | FATE | BLOOD | CELL BIOLOGY | Pluripotent Stem Cells - metabolism | Cell Line | Antigens, Differentiation - biosynthesis | Pluripotent Stem Cells - cytology | T-Lymphocytes - cytology | T-Lymphocytes - metabolism | Humans | Precursor Cells, T-Lymphoid - metabolism | Gene Expression Regulation - physiology | Precursor Cells, T-Lymphoid - cytology | Signal Transduction - physiology | Cell Differentiation - physiology
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5. Full Text Baicalin, a flavone, induces the differentiation of cultured osteoblasts: An action via the Wnt/βcatenin signaling pathway
by Guo, Ava J. Y and Choi, Roy C. Y and Cheung, Anna W. H and Chen, Vicky P and Xu, Sherry L and Dong, Tina T. X and Chen, Ji J and Tsim, Karl W. K
Journal of Biological Chemistry, ISSN 0021-9258, 08/2011, Volume 286, Issue 32, pp. 27882 - 27893
Flavonoids, a group of natural compounds found in a variety of vegetables and herbal medicines, have been intensively reported on regarding their estrogen-like... 
CELLS | BONE LOSS | POSTMENOPAUSAL OSTEOPOROSIS | PROTEIN | SCUTELLARIA-BAICALENSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | HORMONE-REPLACEMENT THERAPY | OSTEOPROTEGERIN | HEME OXYGENASE-1 | GENISTEIN | Phosphorylation - physiology | Transcription, Genetic - drug effects | Active Transport, Cell Nucleus - physiology | Humans | Osteoporosis, Postmenopausal - metabolism | Wnt Signaling Pathway - physiology | Glycogen Synthase Kinase 3 beta | Wnt Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - biosynthesis | Cell Nucleus - metabolism | Female | Flavonoids - pharmacology | Osteoblasts - cytology | Phosphorylation - drug effects | Cell Differentiation - physiology | Osteoporosis, Postmenopausal - prevention & control | Calcification, Physiologic - drug effects | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Calcification, Physiologic - physiology | Rats | Glycogen Synthase Kinase 3 - metabolism | beta Catenin - metabolism | Antigens, Differentiation - biosynthesis | Transcription, Genetic - physiology | Animals | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Active Transport, Cell Nucleus - drug effects | Osteoblasts - metabolism | Osteoporosis | Flavonoids | Signal Transduction | Natural Compounds | beta-Catenin | Cell Differentiation | Bone | Wnt Pathway | Baicalin | Osteogenesis
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6. Full Text MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation
by O'Loghlen, Ana and Muñoz-Cabello, Ana M and Gaspar-Maia, Alexandre and Wu, Hsan-Au and Banito, Ana and Kunowska, Natalia and Racek, Tomas and Pemberton, Helen N and Beolchi, Patrizia and Lavial, Fabrice and Masui, Osamu and Vermeulen, Michiel and Carroll, Thomas and Graumann, Johannes and Heard, Edith and Dillon, Niall and Azuara, Veronique and Snijders, Ambrosius P and Peters, Gordon and Bernstein, Emily and Gil, Jesus
Cell Stem Cell, ISSN 1934-5909, 01/2012, Volume 10, Issue 1, pp. 33 - 46
The Polycomb Group (PcG) of chromatin modifiers regulates pluripotency and differentiation. Mammalian genomes encode multiple homologs of the Polycomb... 
SKELETAL-MUSCLE | CIRCUITRY | DEVELOPMENTAL REGULATORS | EMBRYONIC STEM-CELLS | METHYLATED HISTONE H3 | GENES | SENESCENCE | INK4A | PROTEINS | PLURIPOTENT | CELL & TISSUE ENGINEERING | CELL BIOLOGY | X Chromosome Inactivation - physiology | Embryonic Stem Cells - metabolism | Chromosomes, Human, X - genetics | Embryonic Stem Cells - cytology | Humans | Repressor Proteins - genetics | MicroRNAs - metabolism | Polycomb-Group Proteins | Down-Regulation - physiology | Ubiquitin-Protein Ligases | Mitochondrial Membrane Transport Proteins | Antigens, Differentiation - biosynthesis | Animals | Polycomb Repressive Complex 1 | Repressor Proteins - biosynthesis | Ligases | Cell Line, Tumor | Antigens, Differentiation - genetics | Mice | MicroRNAs - genetics | Chromosomes, Human, X - metabolism | Cell Differentiation - physiology | Repressor Proteins - metabolism
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7. Full Text Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
by Han, Dong Wook and Tapia, Natalia and Hermann, Andreas and Hemmer, Kathrin and Höing, Susanne and Araúzo-Bravo, Marcos J and Zaehres, Holm and Wu, Guangming and Frank, Stefan and Moritz, Sören and Greber, Boris and Yang, Ji Hun and Lee, Hoon Taek and Schwamborn, Jens C and Storch, Alexander and Schöler, Hans R
Cell Stem Cell, ISSN 1934-5909, 04/2012, Volume 10, Issue 4, pp. 465 - 472
Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell... 
MOUSE FIBROBLASTS | FUNCTIONAL-NEURONS | DIRECT CONVERSION | CENTRAL-NERVOUS-SYSTEM | GENERATION | PLURIPOTENCY | DOPAMINERGIC-NEURONS | EXPRESSION | BRAIN | HOMEOBOX GENES | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Gene Expression Regulation - genetics | Cell Dedifferentiation | Transcription Factors - biosynthesis | Transcription Factors - genetics | Neural Stem Cells - cytology | Antigens, Differentiation - biosynthesis | Animals | Antigens, Differentiation - genetics | Fibroblasts - cytology | Mice | Induced Pluripotent Stem Cells - cytology | Neural Stem Cells - metabolism | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism
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8. Full Text A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry
by Zunder, Eli R and Lujan, Ernesto and Goltsev, Yury and Wernig, Marius and Nolan, Garry P
Cell Stem Cell, ISSN 1934-5909, 03/2015, Volume 16, Issue 3, pp. 323 - 337
To analyze cellular reprogramming at the single-cell level, mass cytometry was used to simultaneously measure markers of pluripotency, differentiation,... 
PLURIPOTENT STEM-CELLS | SOMATIC-CELLS | SURFACE MARKERS | PATHWAY | MOUSE | C-MYC | SELF-RENEWAL | DIFFERENTIATION | EXPRESSION | MURINE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Antigens, Differentiation - biosynthesis | Animals | Image Cytometry - methods | Cellular Reprogramming Techniques | Humans | HEK293 Cells | Transcription Factors - biosynthesis | Antigens, Differentiation - genetics | Mice | Transcription Factors - genetics | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism
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9. Full Text Directed differentiation of hippocampal stem/progenitor cells in the adult brain
by Jessberger, Sebastian and Toni, Nicolas and Clemenson Jr, Gregory D and Ray, Jasodhara and Gage, Fred H
Nature Neuroscience, ISSN 1097-6256, 08/2008, Volume 11, Issue 8, pp. 888 - 893
Adult neurogenesis is a lifelong feature of brain plasticity; however, the potency of adult neural stem/progenitor cells in vivo remains unclear. We found that... 
NEURAL STEM-CELLS | PROGENITORS | OLFACTORY-BULB | MULTIPOTENT | IN-VIVO ANALYSIS | NEWLY GENERATED NEURONS | SPINAL-CORD | NEUROGENESIS | DENTATE GYRUS | NEUROSCIENCES | OLIGODENDROCYTES | Oligodendroglia - metabolism | Species Specificity | Cell Survival - genetics | Neurons - cytology | Green Fluorescent Proteins - genetics | Stem Cells - cytology | Lateral Ventricles - cytology | Cell Differentiation - genetics | Female | Neurons - metabolism | Oligodendroglia - cytology | Cell Differentiation - physiology | Genes, Reporter | Stem Cells - virology | Gene Transfer Techniques | Moloney murine leukemia virus - genetics | Neurons - virology | Basic Helix-Loop-Helix Transcription Factors - physiology | Brain - cytology | Basic Helix-Loop-Helix Transcription Factors - genetics | Homeodomain Proteins - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Rats | Transcription Factors - biosynthesis | Oligodendroglia - virology | Transcription Factors - genetics | Hippocampus - cytology | Homeodomain Proteins - genetics | Cell Lineage | Antigens, Differentiation - biosynthesis | Dentate Gyrus - cytology | Animals | Green Fluorescent Proteins - biosynthesis | Stem Cells - physiology | Mice | Neuroplasticity | Physiological aspects | Developmental neurology | Research
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10. Full Text Transcriptome Dynamics of Developing Photoreceptors in Three‐Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
by Kaewkhaw, Rossukon and Kaya, Koray Dogan and Brooks, Matthew and Homma, Kohei and Zou, Jizhong and Chaitankar, Vijender and Rao, Mahendra and Swaroop, Anand
STEM CELLS, ISSN 1066-5099, 12/2015, Volume 33, Issue 12, pp. 3504 - 3518
The derivation of three‐dimensional (3D) stratified neural retina from pluripotent stem cells has permitted investigations of human photoreceptors. We have... 
Retina | Three‐dimensional organoid culture | Global gene profiling | Next generation sequencing | Human rod and cone photoreceptors | Stem cells | Three-dimensional organoid culture | MOUSE | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | EXPRESSION PATTERNS | LEUCINE-ZIPPER NRL | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NEURAL RETINA | HEMATOLOGY | HOMEOBOX GENE | HORMONE-RECEPTOR | PRECURSOR CELLS | EYE DEVELOPMENT | Cell Line | Human Embryonic Stem Cells - metabolism | Antigens, Differentiation - biosynthesis | Human Embryonic Stem Cells - cytology | Humans | Retinal Cone Photoreceptor Cells - cytology | Retinal Rod Photoreceptor Cells - cytology | Transcriptome | Cell Differentiation | Retinal Rod Photoreceptor Cells - metabolism | Retinal Cone Photoreceptor Cells - metabolism | Eye Proteins - biosynthesis | Immunohistochemistry | Rhodopsin | RNA | Genes | Photographic industry | Gene expression | Cell differentiation | Embryonic stem cells | Photoreceptors | Translational and Clinical Research
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11. Full Text Trop2 Identifies a Subpopulation of Murine and Human Prostate Basal Cells with Stem Cell Characteristics
by Andrew S. Goldstein and Devon A. Lawson and Donghui Cheng and Wenyi Sun and Isla P. Garraway and Owen N. Witte
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 52, pp. 20882 - 20887
The epithelium of the adult prostate contains 3 distinct cell types: basal, luminal, and neuroendocrine. Tissue-regenerative activity has been identified... 
Epithelial cells | Neurons | Stem cells | Neural stem cells | Mice | Prostate | Progenitor cells | Prostate cancer | Mesenchymal stem cells | Cancer | Neuroendocrine | Sphere assay | Progenitor | neuroendocrine | MARKER | MULTIDISCIPLINARY SCIENCES | progenitor | NEUROENDOCRINE DIFFERENTIATION | sphere assay | IN-VITRO | EPITHELIAL-CELLS | GENE | COLORECTAL-CANCER | MOUSE PROSTATE | EXPRESSION | CARCINOMA | MAMMARY-GLAND | Adult Stem Cells - cytology | Epithelial Cells - metabolism | Cell Adhesion Molecules - biosynthesis | Humans | Antigens, Neoplasm - biosynthesis | Databases, Genetic | Gene Expression Regulation - physiology | Male | Urethra - cytology | Prostate - metabolism | Adult Stem Cells - metabolism | Antigens, Differentiation - biosynthesis | Membrane Proteins - biosynthesis | Neuroendocrine Cells - cytology | Animals | Antigens, Ly - biosynthesis | Prostate - cytology | Adult | Neuroendocrine Cells - metabolism | Urethra - metabolism | Epithelial Cells - cytology | Integrin alpha6 - biosynthesis | Properties | Identification and classification | Cells | Biological Sciences
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12. Full Text BDCA-2, BDCA-3, and BDCA-4: Three Markers for Distinct Subsets of Dendritic Cells in Human Peripheral Blood
by Dzionek, Andrzej and Fuchs, Anja and Schmidt, Petra and Cremer, Sabine and Zysk, Monika and Miltenyi, Stefan and Buck, David W and Schmitz, Jurgen
The Journal of Immunology, ISSN 0022-1767, 12/2000, Volume 165, Issue 11, pp. 6037 - 6046
We have generated a panel-of mAbs that identify three presumably novel human dendritic cell Ags: BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are... 
ORIGIN | PRECURSOR | TOLERANCE INDUCTION | MONOCYTES | MATURE | RECEPTOR | ALPHA | PLASMACYTOID T-CELLS | GERMINAL-CENTERS | IMMUNOLOGY | LANGERHANS CELLS | Antibody S